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Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis.
Published in:
EMBO Molecular Medicine, 2013, v. 5, n. 1, p. 105, doi. 10.1002/emmm.201201283
By:
- Saddoughi, Sahar A.;
- Gencer, Salih;
- Peterson, Yuri K.;
- Ward, Katherine E.;
- Mukhopadhyay, Archana;
- Oaks, Joshua;
- Bielawski, Jacek;
- Szulc, Zdzislaw M.;
- Thomas, Raquela J.;
- Selvam, Shanmugam P.;
- Senkal, Can E.;
- Garrett‐Mayer, Elizabeth;
- De Palma, Ryan M.;
- Fedarovich, Dzmitry;
- Liu, Angen;
- Habib, Amyn A.;
- Stahelin, Robert V.;
- Perrotti, Danilo;
- Ogretmen, Besim
Publication type:
Article
The death domain-containing kinase RIP1 regulates p27<sup>Kip1</sup> levels through the PI3K–Akt–forkhead pathway.
Published in:
EMBO Reports, 2008, v. 9, n. 8, p. 766, doi. 10.1038/embor.2008.102
By:
- Park, Seongmi;
- Ramnarain, Deepti B;
- Hatanpaa, Kimmo J;
- Mickey, Bruce E;
- Saha, Debabrata;
- Paulmurugan, Ramasamy;
- Madden, Christopher J;
- Wright, Paul S;
- Bhai, Salman;
- Ali, M Aktar;
- Puttaparthi, Krishna;
- Hu, Wei;
- Elliott, Jeffrey L;
- Stuve, Olaf;
- Habib, Amyn A
Publication type:
Article
Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27276-7
By:
- Gong, Ke;
- Guo, Gao;
- Beckley, Nicole A.;
- Yang, Xiaoyao;
- Zhang, Yue;
- Gerber, David E.;
- Minna, John D.;
- Burma, Sandeep;
- Zhao, Dawen;
- Akbay, Esra A.;
- Habib, Amyn A.
Publication type:
Article
Integrin-linked kinase is required for laminin-2-induced oligodendrocyte cell spreading and CNS myelination.
Published in:
Journal of Cell Biology, 2003, v. 163, n. 2, p. 397, doi. 10.1083/jcb.200304154
By:
- Soo Jin Chun, Eugene;
- Rasband, Matthew N.;
- Sidman, Richard L.;
- Habib, Amyn A.;
- Vartanian, Timothy
Publication type:
Article
An inhalable nanoparticulate STING agonist synergizes with radiotherapy to confer long-term control of lung metastases.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13094-5
By:
- Yang Liu;
- Crowe, William N.;
- Lulu Wang;
- Yong Lu;
- Petty, W. Jeffrey;
- Habib, Amyn A.;
- Dawen Zhao
Publication type:
Article
Exposed Phosphatidylserine as a Biomarker for Clear Identification of Breast Cancer Brain Metastases in Mouse Models.
Published in:
Cancers, 2024, v. 16, n. 17, p. 3088, doi. 10.3390/cancers16173088
By:
- Wang, Lulu;
- Zhao, Alan H.;
- Arledge, Chad A.;
- Xing, Fei;
- Chan, Michael D.;
- Brekken, Rolf A.;
- Habib, Amyn A.;
- Zhao, Dawen
Publication type:
Article
Transfer Learning Approach to Vascular Permeability Changes in Brain Metastasis Post-Whole-Brain Radiotherapy.
Published in:
Cancers, 2023, v. 15, n. 10, p. 2703, doi. 10.3390/cancers15102703
By:
- Arledge, Chad A.;
- Crowe, William N.;
- Wang, Lulu;
- Bourland, John Daniel;
- Topaloglu, Umit;
- Habib, Amyn A.;
- Zhao, Dawen
Publication type:
Article
The OMgp gene, a second growth suppressor within the NF1 gene.
Published in:
Oncogene, 1998, v. 16, n. 12, p. 1525, doi. 10.1038/sj.onc.1201683
By:
- Habib, Amyn A;
- Gulcher, Jeffrey R;
- Högnason, Thorbergur;
- Zheng, Leiya;
- Stefánsson, Kári
Publication type:
Article
Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma.
Published in:
Neuro-Oncology, 2019, v. 21, n. 12, p. 1529, doi. 10.1093/neuonc/noz127
By:
- Guo, Gao;
- Gong, Ke;
- Puliyappadamba, Vineshkumar Thidil;
- Panchani, Nishah;
- Pan, Edward;
- Mukherjee, Bipasha;
- Damanwalla, Ziba;
- Bharia, Sabrina;
- Hatanpaa, Kimmo J;
- Gerber, David E;
- Mickey, Bruce E;
- Patel, Toral R;
- Sarkaria, Jann N;
- Zhao, Dawen;
- Burma, Sandeep;
- Habib, Amyn A
Publication type:
Article
DRES-17. ACTIVATION OF FGF SIGNALING PATHWAY CONFERS RESISTANCE TO EGFR INHIBITION IN GBM.
Published in:
Neuro-Oncology, 2018, v. 20, p. vi79, doi. 10.1093/neuonc/noy148.324
By:
- Guo, Gao;
- Gong, Ke;
- Sarkaria, Jann;
- Habib, Amyn
Publication type:
Article
Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks.
Published in:
Carcinogenesis, 2010, v. 31, n. 10, p. 1889, doi. 10.1093/carcin/bgq153
By:
- Camacho, Cristel V.;
- Mukherjee, Bipasha;
- McEllin, Brian;
- Liang-Hao Ding;
- Burong Hu;
- Habib, Amyn A.;
- Xian-Jin Xie;
- Nirodi, Chaitanya S.;
- Saha, Debabrata;
- Story, Michael D.;
- Balajee, Adayabalam S.;
- Bachoo, Robert M.;
- Boothman, David A.;
- Burma, Sandeep
Publication type:
Article
Constitutive and ligand-induced EGFR signalling triggers distinct and mutually exclusive downstream signalling networks.
Published in:
Nature Communications, 2014, v. 5, n. 12, p. 5811, doi. 10.1038/ncomms6811
By:
- Chakraborty, Sharmistha;
- Li, Li;
- Puliyappadamba, Vineshkumar Thidil;
- Guo, Gao;
- Hatanpaa, Kimmo J.;
- Mickey, Bruce;
- Souza, Rhonda F.;
- Vo, Peggy;
- Herz, Joachim;
- Chen, Mei-Ru;
- Boothman, David A.;
- Pandita, Tej K.;
- Wang, David H.;
- Sen, Ganes C.;
- Habib, Amyn A.
Publication type:
Article
Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01392-9
By:
- Newman, Jennifer P.;
- Wang, Grace Y.;
- Arima, Kazuhiko;
- Guan, Shou P.;
- Waters, Michael R.;
- Cavenee, Webster K.;
- Pan, Edward;
- Aliwarga, Edita;
- Chong, Siao T.;
- Kok, Catherine Y. L.;
- Endaya, Berwini B.;
- Habib, Amyn A.;
- Horibe, Tomohisa;
- Ng, Wai H.;
- Ho, Ivy A. W.;
- Hui, Kam M.;
- Kordula, Tomasz;
- Lam, Paula Y. P.
Publication type:
Article
Rapid progression to glioblastoma in a subset of IDH-mutated astrocytomas: a genome-wide analysis.
Published in:
Journal of Neuro-Oncology, 2017, v. 133, n. 1, p. 183, doi. 10.1007/s11060-017-2431-y
By:
- Richardson, Timothy;
- Snuderl, Matija;
- Serrano, Jonathan;
- Karajannis, Matthias;
- Heguy, Adriana;
- Oliver, Dwight;
- Raisanen, Jack;
- Maher, Elizabeth;
- Pan, Edward;
- Barnett, Samuel;
- Cai, Chunyu;
- Habib, Amyn;
- Bachoo, Robert;
- Hatanpaa, Kimmo
Publication type:
Article
High expression of the stem cell marker nestin is an adverse prognostic factor in WHO grade II-III astrocytomas and oligoastrocytomas.
Published in:
Journal of Neuro-Oncology, 2014, v. 117, n. 1, p. 183, doi. 10.1007/s11060-014-1376-7
By:
- Hatanpaa, Kimmo;
- Hu, Tianshen;
- Vemireddy, Vamsidhara;
- Foong, Chan;
- Raisanen, Jack;
- Oliver, Dwight;
- Hiemenz, Matthew;
- Burns, Dennis;
- White, Charles;
- Whitworth, L.;
- Mickey, Bruce;
- Stegner, Martha;
- Habib, Amyn;
- Fink, Karen;
- Maher, Elizabeth;
- Bachoo, Robert
Publication type:
Article
Expression of the Oligodendrocyte-Myelin Glycoprotein by Neurons in the Mouse Central Nervous System.
Published in:
Journal of Neurochemistry, 1998, v. 70, n. 4, p. 1704, doi. 10.1046/j.1471-4159.1998.70041704.x
By:
- Habib, Amyn A.;
- Marton, Linda S.;
- Allwardt, Brenda;
- Gulcher, Jeffrey R.;
- Mikol, Daniel D.;
- Högnason, Thorbergur;
- Chattopadhyay, Naibedya;
- Stefansson, Kári
Publication type:
Article
Phosphatidylserine-Targeted Nanotheranostics for Brain Tumor Imaging and Therapeutic Potential.
Published in:
Molecular Imaging, 2017, v. 16, p. 1, doi. 10.1177/1536012117708722
By:
- Wang, Lulu;
- Habib, Amyn A.;
- Mintz, Akiva;
- Li, King C.;
- Zhao, Dawen
Publication type:
Article
Aerosolized immunotherapeutic nanoparticle inhalation potentiates PD-L1 blockade for locally advanced lung cancer.
Published in:
Nano Research, 2023, v. 16, n. 4, p. 5300, doi. 10.1007/s12274-022-5205-6
By:
- Liu, Yang;
- Crowe, William N.;
- Wang, Lulu;
- Petty, W. Jeffrey;
- Habib, Amyn A.;
- Zhao, Dawen
Publication type:
Article

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