Works matching AU HIGGS, D. R.

Results: 42

Sickle Cell-Hemoglobin D Iran: A Benign Sickle Cell Syndrome.

Published in:

Hemoglobin, 1982, v. 6, n. 1, p. 57, doi. 10.3109/03630268208996934

By:

Serjeant, Beryl;
Myerscough, Elizabeth;
Serjeant, G. R.;
Higgs, D. R.;
Moo-Penn, W. F.

Publication type:

Article

THE CLINICAL AND MOLECULAR HETEROGENEITY OF THE THALASSEMIA SYNDROMES *.

Published in:

Annals of the New York Academy of Sciences, 1980, v. 344, n. 1, p. 83, doi. 10.1111/j.1749-6632.1980.tb33652.x

By:

Weatherall, D. J.;
Clegg, J. B.;
Wood, W. G.;
Old, J. M.;
Higgs, D. R.;
Pressley, L.;
Darbre, P. D.

Publication type:

Article

A MUTATION IN THE POLYADENYLATION SIGNAL OF THE α2 GLOBIN GENE (AATAA→AATA-) AS A CAUSE OF α THALASSAEMIA IN ASIAN INDIANS.

Published in:

British Journal of Haematology, 1994, v. 88, n. 1, p. 225, doi. 10.1111/j.1365-2141.1994.tb05008.x

By:

Hall, G. W.;
Higgs, D. R.;
Murphy, P.;
Villegas, A.;
Miguel, A. de

Publication type:

Article

A PCR-based strategy to detect the common severe determinants of α thalassaemia.

Published in:

British Journal of Haematology, 1992, v. 81, n. 1, p. 104, doi. 10.1111/j.1365-2141.1992.tb08180.x

By:

Bowden, D. K.;
Vickers, M. A.;
Higgs, D. R.

Publication type:

Article

A NOVEL DELETION OF THE ENTIRE α-GLOBIN GENE CLUSTER IN A BRITISH INDIVIDUAL.

Published in:

British Journal of Haematology, 1989, v. 72, n. 3, p. 471, doi. 10.1111/j.1365-2141.1989.tb07736.x

By:

Vickers, M. A.;
Higgs, D. R.

Publication type:

Article

The interaction of alpha thalassaemia and sickle cell-beta° thalassaemia.

Published in:

British Journal of Haematology, 1988, v. 70, n. 4, p. 449, doi. 10.1111/j.1365-2141.1988.00449.x

By:

Vyas, P.;
Higgs, D. R.;
Weatherall, D. J.;
Dunn, D.;
Serjeant, B. E.;
Serjeant, G. R.

Publication type:

Article

Characterization of two deletions that remove the entire human ζ-α globin gene complex (-THAI and -FIL).

Published in:

British Journal of Haematology, 1988, v. 70, n. 2, p. 233, doi. 10.1111/j.1365-2141.1988.tb02469.x

By:

Fischel-Ghodsian, N.;
Vickers, M. A.;
Seip, M.;
Winichagoon, P.;
Higgs, D. R.

Publication type:

Article

α-THALASSAEMIA IN AN ASIAN INDIAN.

Published in:

British Journal of Haematology, 1988, v. 68, n. 2, p. 264, doi. 10.1111/j.1365-2141.1988.tb06201.x

By:

Drysdale, H. C.;
Higgs, D. R.

Publication type:

Article

Characterization of a new α° thalassaemia defect in the South African population.

Published in:

British Journal of Haematology, 1987, v. 66, n. 4, p. 539, doi. 10.1111/j.1365-2141.1987.tb01341.x

By:

Vandenplas, S.;
Higgs, D. R.;
Nicholls, R. D.;
Bester, A. J.;
Mathew, C. G. P.

Publication type:

Article

Haemoglobin gene frequencies in the Jamaican population: a study in 100,000 newborns.

Published in:

British Journal of Haematology, 1986, v. 64, n. 2, p. 253, doi. 10.1111/j.1365-2141.1986.tb04117.x

By:

Serjeant, G. R.;
Serjeant, B. E.;
Forbes, M.;
Hayes, R. J.;
Higgs, D. R.;
Lehmann, H.

Publication type:

Article

ALPHA GLOBIN GENOTYPES IN TWO NORTH EUROPEAN POPULATIONS.

Published in:

British Journal of Haematology, 1986, v. 63, n. 4, p. 796, doi. 10.1111/j.1365-2141.1986.tb07564.x

By:

Flint, J.;
Hill, A. V. S.;
Weatherall, D. J.;
Clegg, J. B.;
Higgs, D. R.

Publication type:

Article

Alpha thalassaemia in an Italian population.

Published in:

British Journal of Haematology, 1986, v. 63, n. 3, p. 497, doi. 10.1111/j.1365-2141.1986.tb07526.x

By:

Velati, C.;
Sampietro, M.;
Biassoni, M.;
Cappellini., M. D.;
Wainscoat, J. S.;
Higgs, D. R.;
Fiorelli, G.

Publication type:

Article

A genetic marker for elevated levels of haemoglobin F in homozygous sickle cell disease?

Published in:

British Journal of Haematology, 1985, v. 60, n. 2, p. 261, doi. 10.1111/j.1365-2141.1985.tb07412.x

By:

Wainscoat, J. S.;
Thein, S. L.;
Higgs, D. R.;
Bell, J. I.;
Weatherall, D. J.;
Al-Awamy, B. H.;
Serjeant, G. R.

Publication type:

Article

Interaction of the ααα globin gene haplotype and sickle haemoglobin.

Published in:

British Journal of Haematology, 1984, v. 57, n. 4, p. 671, doi. 10.1111/j.1365-2141.1984.tb02944.x

By:

Higgs, D. R.;
Clegg, J. B.;
Weatherall, D. J.;
Serjeant, B. E.;
Serjeant, G. R.

Publication type:

Article

Effect of alpha thalassaemia on the rheology of homozygous sickle cell disease.

Published in:

British Journal of Haematology, 1983, v. 55, n. 3, p. 479, doi. 10.1111/j.1365-2141.1983.tb02163.x

By:

Serjeant, B. E.;
Mason, K. P.;
Kenny, M. W.;
Stuart, J.;
Higgs, D. R.;
Weatherall, D. J.;
Hayes, R. J.;
Serjeant, G. R.

Publication type:

Article

Thalassaemia intermedia in Cyprus: the interaction of α and β thalassaemia.

Published in:

British Journal of Haematology, 1983, v. 53, n. 3, p. 411, doi. 10.1111/j.1365-2141.1983.00353.x-i1

By:

Wainscoat, J. S.;
Kanavakis, E.;
Wood, W. G.;
Letsky, E. A.;
Huehns, E. R.;
Marsh, G. W.;
Higgs, D. R.;
Clegg, J. B.;
Weatherall, D. J.

Publication type:

Article

THE SIGNIFICANCE OF HAEMOGLOBIN H IN PATIENTS WITH MENTAL RETARDATION OR MYELOPROLIFERATIVE DISEASE.

Published in:

British Journal of Haematology, 1982, v. 52, n. 3, p. 351, doi. 10.1111/j.1365-2141.1982.tb03904.x

By:

Weatherall, D. J.;
Higgs, D. R.;
Clegg, J. B.;
Wood, W. G.

Publication type:

Article

Haemoglobin Constant Spring has an unstable α chain messenger RNA.

Published in:

British Journal of Haematology, 1982, v. 51, n. 3, p. 405, doi. 10.1111/j.1365-2141.1982.tb02796.x

By:

Hunt, D. M.;
Higgs, D. R.;
Winichagoon, P.;
Clegg, J. B.;
Weatherall, D. J.

Publication type:

Article

α-Globin gene deletions associated with Hb J Tongariki.

Published in:

British Journal of Haematology, 1982, v. 51, n. 2, p. 243, doi. 10.1111/j.1365-2141.1982.tb02777.x

By:

Bowden, D. K.;
Pressley, L.;
Higgs, D. R.;
Clegg, J. B.;
Weatherall, D. J.

Publication type:

Article

INADEQUACY OF Hb BART'S AS AN INDICATOR OF α THALASSAEMIA.

Published in:

British Journal of Haematology, 1982, v. 51, n. 1, p. 177, doi. 10.1111/j.1365-2141.1982.tb07303.x

By:

Higgs, D. R.;
Lamb, J.;
Aldridge, B. E.;
Clegg, J. B.;
Weatherall, D. J.;
Serjeant, B. E.;
Serjeant, G. R.

Publication type:

Article

A NEW TRIPLICATED α-GLOBIN GENE ARRANGEMENT IN MAN.

Published in:

British Journal of Haematology, 1981, v. 49, n. 1, p. 149, doi. 10.1111/j.1365-2141.1981.tb07207.x

By:

Trent, R. J.;
Higgs, D. R.;
Clegg, J. B.;
Weatherall, D. J.

Publication type:

Article

The Genetics and Molecular Basis of Alpha Thalassaemia in Association with Hb S in Jamaican Negroes.

Published in:

British Journal of Haematology, 1981, v. 47, n. 1, p. 43, doi. 10.1111/j.1365-2141.1981.tb02760.x

By:

Higgs, D. R.;
Pressley, L.;
Serjeant, G. R.;
Clegg, J. B.;
Weatherall, D. J.

Publication type:

Article

THE MOLECULAR BASIS FOR THE HAEMOGLOBIN BART'S HYDROPS FETALIS SYNDROME IN CYPRUS.

Published in:

British Journal of Haematology, 1981, v. 47, n. 1, p. 153, doi. 10.1111/j.1365-2141.1981.tb02770.x

By:

Sophocleous, T.;
Higgs, D. R.;
Aldridge, B.;
Trent, R.J.;
Pressley, L.;
Clegg, J. B.;
Weatherall, D. J.

Publication type:

Article

The Genetic Basis of Hb Q-H Disease.

Published in:

British Journal of Haematology, 1980, v. 46, n. 3, p. 387, doi. 10.1111/j.1365-2141.1980.tb05985.x

By:

Higgs, D. R.;
Hunt, D. M.;
Drysdale, H. C.;
Clegg, J. B.;
Pressley, L.;
Weatherall, D. J.

Publication type:

Article

Detection of Alpha Thalassaemia in Negro Infants.

Published in:

British Journal of Haematology, 1980, v. 46, n. 1, p. 39, doi. 10.1111/j.1365-2141.1980.tb05933.x

By:

Higgs, D. R.;
Pressley, L.;
Clegg, J. B.;
Weatherall, D. J.;
Higgs, S.;
Carey, P.;
Serjeant, G. R.

Publication type:

Article

Determination of Alpha Thalassaemia Phenotypes by Messenger RNA Analysis.

Published in:

British Journal of Haematology, 1980, v. 45, n. 1, p. 53, doi. 10.1111/j.1365-2141.1980.tb03810.x

By:

Hunt, D. M.;
Higgs, D. R.;
Old, J. M.;
Clegg, J. B.;
Weatherall, D.J.;
Marsh, G. W.

Publication type:

Article

A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16.

Published in:

Nature, 1985, v. 317, n. 6037, p. 542, doi. 10.1038/317542a0

By:

Reeders, S. T.;
Breuning, M. H.;
Davies, K. E.;
Nicholls, R. D.;
Jarman, A. P.;
Higgs, D. R.;
Pearson, P. L.;
Weatherall, D. J.

Publication type:

Article

α-Thalassaemia caused by a polyadenylation signal mutation.

Published in:

Nature, 1983, v. 306, n. 5941, p. 398, doi. 10.1038/306398a0

By:

Higgs, D. R.;
Goodbourn, S. E. Y.;
Lamb, J.;
Clegg, J. B.;
Weatherall, D. J.;
Proudfoot, N. J.

Publication type:

Article

The changing face of homozygous sickle cell disease: 102 patients over 60 years.

Published in:

International Journal of Laboratory Hematology, 2009, v. 31, n. 6, p. 585, doi. 10.1111/j.1751-553X.2008.01089.x

By:

SERJEANT, G. R.;
SERJEANT, B. E.;
MASON, K. P.;
HAMBLETON, I. R.;
FISHER, C.;
HIGGS, D. R.

Publication type:

Article

α Thalassaemia in two Spanish families.

Published in:

European Journal of Haematology, 1990, v. 44, n. 2, p. 110, doi. 10.1111/j.1600-0609.1990.tb00360.x

By:

Villegas, A.;
Calero, F.;
Vickers, M. A.;
Ayyub, H.;
Higgs, D. R.

Publication type:

Article

Alpha-thalassaemia in Nigeria: Its interaction with sickle-cell disease.

Published in:

European Journal of Haematology, 1987, v. 38, n. 4, p. 370, doi. 10.1111/j.1600-0609.1987.tb00013.x

By:

Falusi, A. G.;
Esan, G. J. F.;
Ayyub, H.;
Higgs, D. R.

Publication type:

Article

The α-Thalassemias.

Published in:

Annals of the New York Academy of Sciences, 1990, v. 612, n. 1, p. 15, doi. 10.1111/j.1749-6632.1990.tb24286.x

By:

HIGGS, D. R.;
WOOD, W. G.;
JARMAN, A. P.;
VICKERS, M. A.;
WILKIE, A. O. M.;
LAMB, J.;
VYAS, P.;
BENNETT, J. P.

Publication type:

Article

Genetic and Molecular Analysis of Mild Forms of Homozygous β-Thalassemia.

Published in:

Annals of the New York Academy of Sciences, 1985, v. 445, n. 1, p. 68, doi. 10.1111/j.1749-6632.1985.tb17176.x

By:

WEATHERALL, D. J.;
WAINSCOAT, J. S.;
THEIN, S. L.;
OLD, J. M.;
WOOD, W. G.;
HIGGS, D. R.;
CLEGG, J. B.

Publication type:

Article

Molecular Rearrangements of the Human α-Globin Gene Cluster.

Published in:

Annals of the New York Academy of Sciences, 1985, v. 445, n. 1, p. 45, doi. 10.1111/j.1749-6632.1985.tb17174.x

By:

HIGGS, D. R.;
HILL, A. V. S.;
NICHOLLS, R.;
GOODBOURN, S. E. Y.;
AYYUB, H.;
TEAL, H.;
CLEGG, J. B.;
WEATHERALL, D. J.

Publication type:

Article

A novel α-globin gene arrangement in man.

Published in:

Nature, 1980, v. 284, n. 5757, p. 632, doi. 10.1038/284632a0

By:

Higgs, D. R.;
Old, J. M.;
Pressley, L.;
Clegg, J. B.;
Weatherall, D. J.

Publication type:

Article

Sequence Comparison of Human and Yeast Telomeres Identifies Structurally Distinct Subtelomeric Domains.

Published in:

Human Molecular Genetics, 1997, v. 6, n. 8, p. 1305, doi. 10.1093/hmg/6.8.1305

By:

Flint, J.;
Bates, G. P.;
Clark, K.;
Dorman, A.;
Willingham, D.;
Roe, B. A.;
Micklem, G.;
Higgs, D. R.;
Louis, E. J.

Publication type:

Article

Chromosomal Stabilisation by a Subtelomeric Rearrangement Involving Two Closely Related Alu Elements.

Published in:

Human Molecular Genetics, 1996, v. 5, n. 8, p. 1163, doi. 10.1093/hmg/5.8.1163

By:

Flint, J.;
Rochette, J.;
Craddock, C. F.;
Dodé, C.;
Vignes, B.;
Horsley, S. W.;
Kearney, L.;
Buckle, V. J.;
Ayyub, H.;
Higgs, D. R.

Publication type:

Article

On-microscope staging of live cells reveals changes in the dynamics of transcriptional bursting during differentiation.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33977-4

By:

Jeziorska, D. M.;
Tunnacliffe, E. A. J.;
Brown, J. M.;
Ayyub, H.;
Sloane-Stanley, J.;
Sharpe, J. A.;
Lagerholm, B. C.;
Babbs, C.;
Smith, A. J. H.;
Buckle, V. J.;
Higgs, D. R.

Publication type:

Article

Function of a new globin gene.

Published in:

Nature, 1987, v. 329, n. 6138, p. 397, doi. 10.1038/329397b0

By:

FISCHEL-GHODSIAN, N.;
HIGGS, D. R.;
BEYER, E.C.

Publication type:

Article

Put in the picture.

Published in:

Nature, 1986, v. 323, n. 6090, p. 679, doi. 10.1038/323679a0

By:

Higgs, D. R.

Publication type:

Article

1990 MACK FORSTER PRIZE LECTURE REVIEW: The Molecular Genetics of the a globin gene family.

Published in:

European Journal of Clinical Investigation, 1990, v. 20, n. 4, p. 340, doi. 10.1111/j.1365-2362.1990.tb01868.x

By:

HIGGS, D. R.

Publication type:

Article

The Alpha Thalassaemias.

Published in:

Cellular & Molecular Life Sciences, 2009, v. 66, n. 7, p. 1154, doi. 10.1007/s00018-008-8529-9

By:

Higgs, D. R.;
Weatherall, D. J.

Publication type:

Article