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Helicobacter pyloriがんタンパク質CagAが 引き起こす胃がん発症のメカニズム.
- Published in:
- Japanese Journal of Helicobacter Research, 2024, v. 26, n. 1, p. 12
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- Article
Bacterial EPIYA effectors - Where do they come from? What are they? Where are they going?
- Published in:
- Cellular Microbiology, 2013, v. 15, n. 3, p. 377, doi. 10.1111/cmi.12040
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- Publication type:
- Article
Helicobacter pylori and gastric carcinogenesis.
- Published in:
- Journal of Gastroenterology, 2009, v. 44, n. 4, p. 239, doi. 10.1007/s00535-009-0014-1
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- Article
The role of Helicobacter pylori CagA in gastric carcinogenesis.
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- 2006
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- Publication type:
- journal article
Kinase Activity of PAR1b, Which Mediates Nuclear Translocation of the BRCA1 Tumor Suppressor, Is Potentiated by Nucleic Acid-Mediated PAR1b Multimerization.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 12, p. 6634, doi. 10.3390/ijms23126634
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- Publication type:
- Article
Mouse Gastric Epithelial Cells Resist CagA Delivery by the Helicobacter pylori Type IV Secretion System.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 5, p. 2492, doi. 10.3390/ijms23052492
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- Publication type:
- Article
The H. pylori CagA Oncoprotein Induces DNA Double Strand Breaks through Fanconi Anemia Pathway Downregulation and Replication Fork Collapse.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1661, doi. 10.3390/ijms23031661
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- Publication type:
- Article
IL-2 Signaling Involves Recruitment and Activation of Multiple Protein Tyrosine Kinases by the IL-2 Receptor<sup>a</sup>.
- Published in:
- Annals of the New York Academy of Sciences, 1995, v. 766, n. 1, p. 235, doi. 10.1111/j.1749-6632.1995.tb26671.x
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- Publication type:
- Article
Response: strain-specific activation of NF-κB by Helicobacter pylori CagA.
- Published in:
- EMBO Reports, 2010, v. 11, n. 1, p. 11, doi. 10.1038/embor.2009.269
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- Publication type:
- Article
Helicobacter pylori CagA activates NF-κB by targeting TAK1 for TRAF6-mediated Lys 63 ubiquitination.
- Published in:
- EMBO Reports, 2009, v. 10, n. 11, p. 1242, doi. 10.1038/embor.2009.210
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- Publication type:
- Article
Association between Diversity in the Src Homology 2 Domain--Containing Tyrosine Phosphatase Binding Site of Helicobacter pylori CagA Protein and Gastric Atrophy and Cancer.
- Published in:
- Journal of Infectious Diseases, 2004, v. 189, n. 5, p. 820, doi. 10.1086/381782
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- Publication type:
- Article
The CagA Protein of Helicobacter pylori Is Translocated into Epithelial Cells and Binds to SHP-2 in Human Gastric Mucosa.
- Published in:
- Journal of Infectious Diseases, 2003, v. 187, n. 2, p. 334, doi. 10.1086/367807
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- Publication type:
- Article
Impact of structural polymorphism for the Helicobacter pylori CagA oncoprotein on binding to polarity-regulating kinase PAR1b.
- Published in:
- Scientific Reports, 2016, p. 30031, doi. 10.1038/srep30031
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- Publication type:
- Article
Exosomes as nanocarriers for systemic delivery of the Helicobacter pylori virulence factor CagA.
- Published in:
- Scientific Reports, 2016, p. 18346, doi. 10.1038/srep18346
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- Publication type:
- Article
Dramatic increase in SHP2 binding activity of Helicobacter pylori Western CagA by EPIYA-C duplication: its implications in gastric carcinogenesis.
- Published in:
- Scientific Reports, 2015, p. 15749, doi. 10.1038/srep15749
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- Publication type:
- Article
Helicobacter pylori CagA Triggers Expression of the Bactericidal Lectin REG3γ via Gastric STAT3 Activation.
- Published in:
- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0030786
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- Publication type:
- Article
Evolution of cagA Oncogene of Helicobacter pylori through Recombination.
- Published in:
- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023499
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- Publication type:
- Article
Helicobacter pylori-Induced Histone Modification, Associated Gene Expression in Gastric Epithelial Cells, and Its Implication in Pathogenesis.
- Published in:
- PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0009875
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- Publication type:
- Article
Pathogenesis of Helicobacter pylori Infection.
- Published in:
- Helicobacter, 2006, v. 11, p. 14, doi. 10.1111/j.1478-405X.2006.00424.x
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- Publication type:
- Article
Paired-like homeoprotein ESXR1 acts as a sequence-specific transcriptional repressor of the human K-ras gene.
- Published in:
- Oncogene, 2005, v. 24, n. 38, p. 5878, doi. 10.1038/sj.onc.1208736
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- Publication type:
- Article
Paired-like homeodomain protein ESXR1 possesses a cleavable C-terminal region that inhibits cyclin degradation.
- Published in:
- Oncogene, 2004, v. 23, n. 39, p. 6590, doi. 10.1038/sj.onc.1207884
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- Publication type:
- Article
Effects of Helicobacter pylori CagA protein on the growth and survival of B lymphocytes, the origin of MALT lymphoma.
- Published in:
- Oncogene, 2003, v. 22, n. 51, p. 8337, doi. 10.1038/sj.onc.1207028
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- Publication type:
- Article
Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity.
- Published in:
- Nature, 2007, v. 447, n. 7142, p. 330, doi. 10.1038/nature05765
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- Publication type:
- Article
Granulocytic differentiation of myeloid progenitor cells by p130, the retinoblastoma tumor suppressor homologue.
- Published in:
- Oncogene, 1999, v. 18, n. 46, p. 6209, doi. 10.1038/sj.onc.1203044
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- Publication type:
- Article
Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis.
- Published in:
- Cancer Science, 2005, v. 96, n. 12, p. 835, doi. 10.1111/j.1349-7006.2005.00130.x
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- Publication type:
- Article
Conditional gene silencing utilizing the lac repressor reveals a role of SHP-2 in cagA-positive Helicobacter pylori pathogenicity.
- Published in:
- Cancer Science, 2004, v. 95, n. 5, p. 442, doi. 10.1111/j.1349-7006.2004.tb03229.x
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- Publication type:
- Article
Ras and Signal Transducer and Activator of Transcription (STAT) Are Essential and Sufficient Downstream Components of Janus Kinases in Cell Proliferation.
- Published in:
- Cancer Science, 2000, v. 91, n. 5, p. 527, doi. 10.1111/j.1349-7006.2000.tb00977.x
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- Publication type:
- Article
DYSREGULATION OF GROWTH FACTOR-RECEPTOR SYSTEM IN CELLULAR TRANSFORMATION.
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- Cancer Science, 1988, v. 79, n. 8, p. 885, doi. 10.1111/j.1349-7006.1988.tb00052.x
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- Publication type:
- Article
Deregulation of β-catenin signal by Helicobacter pylori CagA requires the CagA-multimerization sequence.
- Published in:
- International Journal of Cancer, 2008, v. 122, n. 4, p. 823, doi. 10.1002/ijc.23190
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- Publication type:
- Article
Helicobacter pylori CagA-a bacterial intruder conspiring gastric carcinogenesis.
- Published in:
- International Journal of Cancer, 2006, v. 119, n. 6, p. 1217, doi. 10.1002/ijc.21831
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- Publication type:
- Article
Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways.
- Published in:
- Nature Communications, 2016, v. 7, n. 9, p. 12887, doi. 10.1038/ncomms12887
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- Publication type:
- Article
Development of a Novel Method to Detect Helicobacter pyloricagA Genotype from Paraffin-Embedded Materials: Comparison between Patients with Duodenal Ulcer and Gastric Cancer in Young Japanese.
- Published in:
- Digestion, 2006, v. 73, n. 1, p. 47, doi. 10.1159/000092014
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- Article
Differential oncogenic potential of geographically distinct Helicobacter pylori CagA isoforms in mice.
- Published in:
- International Journal of Cancer, 2009, v. 125, n. 11, p. 2497, doi. 10.1002/ijc.24740
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- Publication type:
- Article
Sequence Polymorphism and Intrinsic Structural Disorder as Related to Pathobiological Performance of the Helicobacter pylori CagA Oncoprotein.
- Published in:
- Toxins, 2017, v. 9, n. 4, p. 136, doi. 10.3390/toxins9040136
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- Publication type:
- Article
The Helicobacter pylori CagA oncoprotein disrupts Wnt/PCP signaling and promotes hyperproliferation of pyloric gland base cells.
- Published in:
- Science Signaling, 2023, v. 16, n. 794, p. 1, doi. 10.1126/scisignal.abp9020
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- Publication type:
- Article
Structure and function of Helicobacter pylori CagA, the first-identified bacterial protein involved in human cancer.
- Published in:
- Proceedings of the Japan Academy, Series A: Mathematical Sciences, 2017, v. 93, n. 4b, p. 196, doi. 10.2183/pjab.93.013
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- Publication type:
- Article
Stability of Helicobacter pylori CagA oncoprotein in human gastric epithelial cells
- Published in:
- FEBS Letters, 2009, v. 583, n. 14, p. 2414, doi. 10.1016/j.febslet.2009.06.043
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- Publication type:
- Article
Evaluating the origin and virulence of a Helicobacter pylori cagA-positive strain isolated from a non-human primate.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-34425-4
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- Publication type:
- Article
Hyaluronan Degradation Promotes Cancer via Hippo‐YAP Signaling: An Intervention Point for Cancer Therapy.
- Published in:
- BioEssays, 2020, v. 42, n. 7, p. 1, doi. 10.1002/bies.202000005
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- Publication type:
- Article
Helicobacter pylori‐induced DNA double‐stranded break in the development of gastric cancer.
- Published in:
- Cancer Science, 2022, v. 113, n. 6, p. 1909, doi. 10.1111/cas.15357
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- Publication type:
- Article
Helicobacter pylori CagA oncoprotein interacts with SHIP2 to increase its delivery into gastric epithelial cells.
- Published in:
- Cancer Science, 2020, v. 111, n. 5, p. 1596, doi. 10.1111/cas.14391
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- Publication type:
- Article
Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.
- Published in:
- Cancer Science, 2017, v. 108, n. 5, p. 931, doi. 10.1111/cas.13211
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- Publication type:
- Article
C-terminal Src kinase-mediated EPIYA phosphorylation of Pragmin creates a feed-forward C-terminal Src kinase activation loop that promotes cell motility.
- Published in:
- Cancer Science, 2016, v. 107, n. 7, p. 972, doi. 10.1111/cas.12962
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- Publication type:
- Article
Natural variant of the Helicobacter pylori CagA oncoprotein that lost the ability to interact with PAR1.
- Published in:
- Cancer Science, 2014, v. 105, n. 3, p. 245, doi. 10.1111/cas.12342
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- Publication type:
- Article
Anthropological and clinical implications for the structural diversity of the Helicobacter pylori CagA oncoprotein.
- Published in:
- Cancer Science, 2011, v. 102, n. 1, p. 36, doi. 10.1111/j.1349-7006.2010.01743.x
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- Publication type:
- Article
Structural and functional diversity in the PAR1b/MARK2-binding region of Helicobacter pylori CagA.
- Published in:
- Cancer Science, 2008, v. 99, n. 10, p. 2004, doi. 10.1111/j.1349-7006.2008.00950.x
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- Publication type:
- Article
Oncogenic mechanisms of the Helicobacter pylori CagA protein.
- Published in:
- Nature Reviews Cancer, 2004, v. 4, n. 9, p. 688, doi. 10.1038/nrc1433
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- Publication type:
- Article
Role of interleukin 2 receptor β chain in initiating anti-CD3 and interleukin 2-induced proliferation of human resting T cells.
- Published in:
- European Journal of Immunology, 1990, v. 20, n. 9, p. 1981, doi. 10.1002/eji.1830200916
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- Publication type:
- Article
Human interleukin 2 (IL 2) receptor β chain allows transduction of IL 2-induced proliferation signal(s) in a murine cell line.
- Published in:
- European Journal of Immunology, 1989, v. 19, n. 12, p. 2375, doi. 10.1002/eji.1830191229
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- Publication type:
- Article
Functional interleukin 2 receptors on B cells lacking Tac antigens.
- Published in:
- European Journal of Immunology, 1987, v. 17, n. 9, p. 1379, doi. 10.1002/eji.1830170925
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- Article