Found: 26

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  • The genomic and transcriptional landscape of primary central nervous system lymphoma.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30050-y
    By:
    • Radke, Josefine;
    • Ishaque, Naveed;
    • Koll, Randi;
    • Gu, Zuguang;
    • Schumann, Elisa;
    • Sieverling, Lina;
    • Uhrig, Sebastian;
    • Hübschmann, Daniel;
    • Toprak, Umut H.;
    • López, Cristina;
    • Hostench, Xavier Pastor;
    • Borgoni, Simone;
    • Juraeva, Dilafruz;
    • Pritsch, Fabienne;
    • Paramasivam, Nagarajan;
    • Balasubramanian, Gnana Prakash;
    • Schlesner, Matthias;
    • Sahay, Shashwat;
    • Weniger, Marc;
    • Pehl, Debora
    Publication type:
    Article

  • Poly(ADP‐ribose) polymerase inhibition in pancreatic cancer.

    Published in:
    Genes, Chromosomes & Cancer, 2021, v. 60, n. 5, p. 373, doi. 10.1002/gcc.22932
    By:
    • Singh, Hans Martin;
    • Bailey, Peter;
    • Hübschmann, Daniel;
    • Berger, Anne Katrin;
    • Neoptolemos, John P.;
    • Jäger, Dirk;
    • Siveke, Jens;
    • Springfeld, Christoph
    Publication type:
    Article

  • Analysis of mutational signatures with yet another package for signature analysis.

    Published in:
    Genes, Chromosomes & Cancer, 2021, v. 60, n. 5, p. 314, doi. 10.1002/gcc.22918
    By:
    • Hübschmann, Daniel;
    • Jopp‐Saile, Lea;
    • Andresen, Carolin;
    • Krämer, Stephen;
    • Gu, Zuguang;
    • Heilig, Christoph E.;
    • Kreutzfeldt, Simon;
    • Teleanu, Veronica;
    • Fröhling, Stefan;
    • Eils, Roland;
    • Schlesner, Matthias
    Publication type:
    Article

  • Germline SDHB‐inactivating mutation in gastric spindle cell sarcoma.

    Published in:
    Genes, Chromosomes & Cancer, 2020, v. 59, n. 10, p. 601, doi. 10.1002/gcc.22876
    By:
    • Heilig, Christoph E.;
    • Horak, Peter;
    • Lipka, Daniel B.;
    • Mock, Andreas;
    • Uhrig, Sebastian;
    • Kreutzfeldt, Simon;
    • Richter, Susan;
    • Gieldon, Laura;
    • Fröhlich, Martina;
    • Hutter, Barbara;
    • Hübschmann, Daniel;
    • Teleanu, Veronica;
    • Schmier, Johann‐Wilhelm;
    • Philipzen, Johannes;
    • Beuthien‐Baumann, Bettina;
    • Schröck, Evelin;
    • Deimling, Andreas;
    • Bauer, Sebastian;
    • Heining, Christoph;
    • Mechtersheimer, Gunhild
    Publication type:
    Article

  • rGREAT: an R/bioconductor package for functional enrichment on genomic regions.

    Published in:
    Bioinformatics, 2023, v. 39, n. 1, p. 1, doi. 10.1093/bioinformatics/btac745
    By:
    • Gu, Zuguang;
    • Hübschmann, Daniel
    Publication type:
    Article

  • Pkgndep: a tool for analyzing dependency heaviness of R packages.

    Published in:
    Bioinformatics, 2022, v. 38, n. 17, p. 4248, doi. 10.1093/bioinformatics/btac449
    By:
    • Gu, Zuguang;
    • Hübschmann, Daniel
    Publication type:
    Article

  • Make Interactive Complex Heatmaps in R.

    Published in:
    Bioinformatics, 2022, v. 38, n. 5, p. 1460, doi. 10.1093/bioinformatics/btab806
    By:
    • Gu, Zuguang;
    • Hübschmann, Daniel
    Publication type:
    Article

  • spiralize: an R package for visualizing data on spirals.

    Published in:
    Bioinformatics, 2022, v. 38, n. 5, p. 1434, doi. 10.1093/bioinformatics/btab778
    By:
    • Gu, Zuguang;
    • Hübschmann, Daniel
    Publication type:
    Article

  • Defective homologous recombination DNA repair as therapeutic target in advanced chordoma.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09633-9
    By:
    • Gröschel, Stefan;
    • Hübschmann, Daniel;
    • Raimondi, Francesco;
    • Horak, Peter;
    • Warsow, Gregor;
    • Fröhlich, Martina;
    • Klink, Barbara;
    • Gieldon, Laura;
    • Hutter, Barbara;
    • Kleinheinz, Kortine;
    • Bonekamp, David;
    • Marschal, Oliver;
    • Chudasama, Priya;
    • Mika, Jagoda;
    • Groth, Marie;
    • Uhrig, Sebastian;
    • Krämer, Stephen;
    • Heining, Christoph;
    • Heilig, Christoph E.;
    • Richter, Daniela
    Publication type:
    Article

  • Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-08578-3
    By:
    • López, Cristina;
    • Kleinheinz, Kortine;
    • Aukema, Sietse M.;
    • Rohde, Marius;
    • Bernhart, Stephan H.;
    • Hübschmann, Daniel;
    • Wagener, Rabea;
    • Toprak, Umut H.;
    • Raimondi, Francesco;
    • Kreuz, Markus;
    • Waszak, Sebastian M.;
    • Huang, Zhiqin;
    • Sieverling, Lina;
    • Paramasivam, Nagarajan;
    • Seufert, Julian;
    • Sungalee, Stephanie;
    • Russell, Robert B.;
    • Bausinger, Julia;
    • Kretzmer, Helene;
    • Ammerpohl, Ole
    Publication type:
    Article

  • Detection of Structural Variants in Circulating Cell-Free DNA from Sarcoma Patients Using Next Generation Sequencing.

    Published in:
    Cancers, 2020, v. 12, n. 12, p. 3627, doi. 10.3390/cancers12123627
    By:
    • Mc Connell, Lauren;
    • Gazdova, Jana;
    • Beck, Katja;
    • Srivastava, Shambhavi;
    • Harewood, Louise;
    • Stewart, JP;
    • Hübschmann, Daniel;
    • Stenzinger, Albrecht;
    • Glimm, Hanno;
    • Heilig, Christoph E.;
    • Fröhling, Stefan;
    • Gonzalez, David
    Publication type:
    Article

  • Targeted therapy of advanced parathyroid carcinoma guided by genomic and transcriptomic profiling.

    Published in:
    Molecular Oncology, 2023, v. 17, n. 7, p. 1343, doi. 10.1002/1878-0261.13398
    By:
    • Teleanu, Maria‐Veronica;
    • Fuss, Carmina T.;
    • Paramasivam, Nagarajan;
    • Pirmann, Sebastian;
    • Mock, Andreas;
    • Terkamp, Christoph;
    • Kircher, Stefan;
    • Landwehr, Laura‐Sophie;
    • Lenschow, Christina;
    • Schlegel, Nicolas;
    • Stenzinger, Albrecht;
    • Jahn, Arne;
    • Fassnacht, Martin;
    • Glimm, Hanno;
    • Hübschmann, Daniel;
    • Fröhling, Stefan;
    • Kroiss, Matthias
    Publication type:
    Article

  • Outcome of immunotherapy in adrenocortical carcinoma: a retrospective cohort study.

    Published in:
    European Journal of Endocrinology, 2023, v. 188, n. 6, p. 485, doi. 10.1093/ejendo/lvad054
    By:
    • Remde, Hanna;
    • Schmidt-Pennington, Laura;
    • Reuter, Miriam;
    • Landwehr, Laura-Sophie;
    • Jensen, Marie;
    • Lahner, Harald;
    • Kimpel, Otilia;
    • Altieri, Barbara;
    • Laubner, Katharina;
    • Schreiner, Jochen;
    • Bojunga, Joerg;
    • Kircher, Stefan;
    • Kunze, Catarina Alisa;
    • Pohrt, Anne;
    • Teleanu, Maria-Veronica;
    • Hübschmann, Daniel;
    • Stenzinger, Albrecht;
    • Glimm, Hanno;
    • Fröhling, Stefan;
    • Fassnacht, Martin
    Publication type:
    Article

  • Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model.

    Published in:
    Neuro-Oncology, 2021, v. 23, n. 12, p. 2028, doi. 10.1093/neuonc/noab127
    By:
    • Simovic, Milena;
    • Bolkestein, Michiel;
    • Moustafa, Mahmoud;
    • Wong, John K L;
    • Körber, Verena;
    • Benedetto, Sarah;
    • Khalid, Umar;
    • Schreiber, Hannah Sophia;
    • Jugold, Manfred;
    • Korshunov, Andrey;
    • Hübschmann, Daniel;
    • Mack, Norman;
    • Brons, Stephan;
    • Wei, Pei-Chi;
    • Breckwoldt, Michael O;
    • Heiland, Sabine;
    • Bendszus, Martin;
    • Debus, Jürgen;
    • Höfer, Thomas;
    • Zapatka, Marc
    Publication type:
    Article

  • Case Report: Abdominal Lymph Node Metastases of Parathyroid Carcinoma: Diagnostic Workup, Molecular Diagnosis, and Clinical Management.

    Published in:
    Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.643328
    By:
    • Lenschow, Christina;
    • Fuss, Carmina Teresa;
    • Kircher, Stefan;
    • Buck, Andreas;
    • Kickuth, Ralph;
    • Reibetanz, Joachim;
    • Wiegering, Armin;
    • Stenzinger, Albrecht;
    • Hübschmann, Daniel;
    • Germer, Christoph Thomas;
    • Fassnacht, Martin;
    • Fröhling, Stefan;
    • Schlegel, Nicolas;
    • Kroiss, Matthias
    Publication type:
    Article

  • Improve consensus partitioning via a hierarchical procedure.

    Published in:
    Briefings in Bioinformatics, 2022, v. 23, n. 3, p. 1, doi. 10.1093/bib/bbac048
    By:
    • Gu, Zuguang;
    • Hübschmann, Daniel
    Publication type:
    Article

  • Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity.

    Published in:
    Nature Communications, 2016, v. 7, n. 6, p. 11845, doi. 10.1038/ncomms11845
    By:
    • Hoefflin, Rouven;
    • Lahrmann, Bernd;
    • Warsow, Gregor;
    • Hübschmann, Daniel;
    • Spath, Cathleen;
    • Walter, Britta;
    • Chen, Xin;
    • Hofer, Luisa;
    • Macher-Goeppinger, Stephan;
    • Tolstov, Yanis;
    • Korzeniewski, Nina;
    • Duensing, Anette;
    • Grüllich, Carsten;
    • Jäger, Dirk;
    • Perner, Sven;
    • Schönberg, Gita;
    • Nyarangi-Dix, Joanne;
    • Isaac, Sanjay;
    • Hatiboglu, Gencay;
    • Teber, Dogu
    Publication type:
    Article

  • Precision oncology based on omics data: The NCT Heidelberg experience.

    Published in:
    International Journal of Cancer, 2017, v. 141, n. 5, p. 877, doi. 10.1002/ijc.30828
    By:
    • Horak, Peter;
    • Klink, Barbara;
    • Heining, Christoph;
    • Gröschel, Stefan;
    • Hutter, Barbara;
    • Fröhlich, Martina;
    • Uhrig, Sebastian;
    • Hübschmann, Daniel;
    • Schlesner, Matthias;
    • Eils, Roland;
    • Richter, Daniela;
    • Pfütze, Katrin;
    • Geörg, Christina;
    • Meißburger, Bettina;
    • Wolf, Stephan;
    • Schulz, Angela;
    • Penzel, Roland;
    • Herpel, Esther;
    • Kirchner, Martina;
    • Lier, Amelie
    Publication type:
    Article

  • Mutational patterns and regulatory networks in epigenetic subgroups of meningioma.

    Published in:
    Acta Neuropathologica, 2019, v. 138, n. 2, p. 295, doi. 10.1007/s00401-019-02008-w
    By:
    • Paramasivam, Nagarajan;
    • Hübschmann, Daniel;
    • Toprak, Umut H;
    • Ishaque, Naveed;
    • Neidert, Marian;
    • Schrimpf, Daniel;
    • Stichel, Damian;
    • Reuss, David;
    • Sievers, Philipp;
    • Reinhardt, Annekathrin;
    • Wefers, Annika K.;
    • Jones, David T. W.;
    • Gu, Zuguang;
    • Werner, Johannes;
    • Uhrig, Sebastian;
    • Wirsching, Hans-Georg;
    • Schick, Matthias;
    • Bewerunge-Hudler, Melanie;
    • Beck, Katja;
    • Brehmer, Stephanie
    Publication type:
    Article

  • Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature.

    Published in:
    2017
    By:
    • Sahm, Felix;
    • Toprak, Umut;
    • Hübschmann, Daniel;
    • Kleinheinz, Kortine;
    • Buchhalter, Ivo;
    • Sill, Martin;
    • Stichel, Damian;
    • Schick, Matthias;
    • Bewerunge-Hudler, Melanie;
    • Schrimpf, Daniel;
    • Zadeh, Gelareh;
    • Aldape, Ken;
    • Herold-Mende, Christel;
    • Beck, Katja;
    • Staszewski, Ori;
    • Prinz, Marco;
    • Harosh, Carmit;
    • Eils, Roland;
    • Sturm, Dominik;
    • Jones, David
    Publication type:
    Letter

  • cola: an R/Bioconductor package for consensus partitioning through a general framework.

    Published in:
    Nucleic Acids Research, 2021, v. 49, n. 3, p. e15, doi. 10.1093/nar/gkaa1146
    By:
    • Gu, Zuguang;
    • Schlesner, Matthias;
    • Hübschmann, Daniel
    Publication type:
    Article

  • Integrative genomic and transcriptomic analysis of leiomyosarcoma.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02602-0
    By:
    • Chudasama, Priya;
    • Mughal, Sadaf S.;
    • Sanders, Mathijs A.;
    • Hübschmann, Daniel;
    • Inn Chung;
    • Deeg, Katharina I.;
    • Siao-Han Wong;
    • Rabe, Sophie;
    • Hlevnjak, Mario;
    • Zapatka, Marc;
    • Ernst, Aurélie;
    • Kleinheinz, Kortine;
    • Schlesner, Matthias;
    • Sieverling, Lina;
    • Klink, Barbara;
    • Schröck, Evelin;
    • Hoogenboezem, Remco M.;
    • Kasper, Bernd;
    • Heilig, Christoph E.;
    • Egerer, Gerlinde
    Publication type:
    Article

  • ShinyButchR: Interactive NMF-based decomposition workflow of genome-scale datasets.

    Published in:
    Biology Methods & Protocols, 2020, v. 5, n. 1, p. 1, doi. 10.1093/biomethods/bpaa022
    By:
    • Quintero, Andres;
    • Hübschmann, Daniel;
    • Kurzawa, Nils;
    • Steinhauser, Sebastian;
    • Rentzsch, Philipp;
    • Krämer, Stephen;
    • Andresen, Carolin;
    • Park, Jeongbin;
    • Eils, Roland;
    • Schlesner, Matthias;
    • Herrmann, Carl
    Publication type:
    Article

  • An AI-based segmentation and analysis pipeline for high-field MR monitoring of cerebral organoids.

    Published in:
    Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-48343-7
    By:
    • Deininger, Luca;
    • Jung-Klawitter, Sabine;
    • Mikut, Ralf;
    • Richter, Petra;
    • Fischer, Manuel;
    • Karimian-Jazi, Kianush;
    • Breckwoldt, Michael O.;
    • Bendszus, Martin;
    • Heiland, Sabine;
    • Kleesiek, Jens;
    • Opladen, Thomas;
    • Hübschmann, Oya Kuseyri;
    • Hübschmann, Daniel;
    • Schwarz, Daniel
    Publication type:
    Article

  • Framework for quality assessment of whole genome cancer sequences.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18688-y
    By:
    • Whalley, Justin P.;
    • Buchhalter, Ivo;
    • Rheinbay, Esther;
    • Raine, Keiran M.;
    • Stobbe, Miranda D.;
    • Kleinheinz, Kortine;
    • Werner, Johannes;
    • Beltran, Sergi;
    • Gut, Marta;
    • Hübschmann, Daniel;
    • Hutter, Barbara;
    • Livitz, Dimitri;
    • Perry, Marc D.;
    • Rosenberg, Mara;
    • Saksena, Gordon;
    • Trotta, Jean-Rémi;
    • Eils, Roland;
    • Gerhard, Daniela S.;
    • Campbell, Peter J.;
    • Schlesner, Matthias
    Publication type:
    Article

  • The landscape of chromothripsis across adult cancer types.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16134-7
    By:
    • Voronina, Natalia;
    • Wong, John K. L.;
    • Hübschmann, Daniel;
    • Hlevnjak, Mario;
    • Uhrig, Sebastian;
    • Heilig, Christoph E.;
    • Horak, Peter;
    • Kreutzfeldt, Simon;
    • Mock, Andreas;
    • Stenzinger, Albrecht;
    • Hutter, Barbara;
    • Fröhlich, Martina;
    • Brors, Benedikt;
    • Jahn, Arne;
    • Klink, Barbara;
    • Gieldon, Laura;
    • Sieverling, Lina;
    • Feuerbach, Lars;
    • Chudasama, Priya;
    • Beck, Katja
    Publication type:
    Article