Works by Hübner, Marc P.


Results: 65
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    Mesoporous Silica as an Alternative Vehicle to Overcome Solubility Limitations.

    Published in:
    Pharmaceutics, 2024, v. 16, n. 3, p. 386, doi. 10.3390/pharmaceutics16030386
    By:
    • Becker, Tim;
    • Heitkötter, Jan;
    • Krome, Anna K.;
    • Schiefer, Andrea;
    • Pfarr, Kenneth;
    • Ehrens, Alexandra;
    • Grosse, Miriam;
    • Sandargo, Birthe;
    • Stammberger, Ingo;
    • Stadler, Marc;
    • Hübner, Marc P.;
    • Kehraus, Stefan;
    • Hoerauf, Achim;
    • Wagner, Karl G.
    Publication type:
    Article
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    In Vitro–In Vivo Relationship in Mini-Scale—Enabling Formulations of Corallopyronin A.

    Published in:
    Pharmaceutics, 2022, v. 14, n. 8, p. 1657, doi. 10.3390/pharmaceutics14081657
    By:
    • Becker, Tim;
    • Krome, Anna K.;
    • Vahdati, Sahel;
    • Schiefer, Andrea;
    • Pfarr, Kenneth;
    • Ehrens, Alexandra;
    • Aden, Tilman;
    • Grosse, Miriam;
    • Jansen, Rolf;
    • Alt, Silke;
    • Hesterkamp, Thomas;
    • Stadler, Marc;
    • Hübner, Marc P.;
    • Kehraus, Stefan;
    • König, Gabriele M.;
    • Hoerauf, Achim;
    • Wagner, Karl G.
    Publication type:
    Article
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    Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A.

    Published in:
    Pharmaceutics, 2020, v. 12, n. 11, p. 1105, doi. 10.3390/pharmaceutics12111105
    By:
    • Krome, Anna K.;
    • Becker, Tim;
    • Kehraus, Stefan;
    • Schiefer, Andrea;
    • Steinebach, Christian;
    • Aden, Tilman;
    • Frohberger, Stefan J.;
    • López Mármol, Álvaro;
    • Kapote, Dnyaneshwar;
    • Jansen, Rolf;
    • Chaverra-Muñoz, Lillibeth;
    • Hübner, Marc P.;
    • Pfarr, Kenneth;
    • Hesterkamp, Thomas;
    • Stadler, Marc;
    • Gütschow, Michael;
    • König, Gabriele M.;
    • Hoerauf, Achim;
    • Wagner, Karl G.
    Publication type:
    Article
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    Hemophagocytic lymphohistiocytosis—how common and how severe is it as a complication of malaria? Retrospective case series and review of the literature.

    Published in:
    Infection, 2024, v. 52, n. 2, p. 471, doi. 10.1007/s15010-023-02104-w
    By:
    • Orth, Hans Martin;
    • Wiemer, Dorothea;
    • Schneitler, Sophie;
    • Schönfeld, Andreas;
    • Holtfreter, Martha Charlotte;
    • Gliga, Smaranda;
    • Fuchs, Andre;
    • Pfäfflin, Frieder;
    • Denkinger, Claudia Maria;
    • Kalbitz, Sven;
    • Fritzsche, Carlos;
    • Hübner, Marc P.;
    • Trauth, Janina;
    • Jensen, Björn-Erik Ole;
    • Luedde, Tom;
    • Feldt, Torsten
    Publication type:
    Article
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    Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode Litomosoides sigmodontis.

    Published in:
    Vaccines, 2023, v. 11, n. 5, p. 966, doi. 10.3390/vaccines11050966
    By:
    • Scheunemann, Johanna F.;
    • Risch, Frederic;
    • Reichwald, Julia J.;
    • Lenz, Benjamin;
    • Neumann, Anna-Lena;
    • Garbe, Stephan;
    • Frohberger, Stefan J.;
    • Koschel, Marianne;
    • Ajendra, Jesuthas;
    • Rothe, Maximilian;
    • Latz, Eicke;
    • Coch, Christoph;
    • Hartmann, Gunther;
    • Schumak, Beatrix;
    • Hoerauf, Achim;
    • Hübner, Marc P.
    Publication type:
    Article
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    Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis.

    Published in:
    Frontiers in Microbiology, 2024, p. 1, doi. 10.3389/fmicb.2024.1346068
    By:
    • Hegde, Shrilakshmi;
    • Marriott, Amy E.;
    • Pionnier, Nicolas;
    • Steven, Andrew;
    • Bulman, Christina;
    • Gunderson, Emma;
    • Voge, Ian;
    • Kosche, Marianne;
    • Ehrens, Alexandra;
    • Lustigman, Sara;
    • Voronin, Denis;
    • Tricoche, Nancy;
    • Hoerauf, Achim;
    • Hübner, Marc P.;
    • Sankanari, Judy;
    • Aljayyoussi, Ghaith;
    • Gusovsky, Fabian;
    • Dagley, Jessica;
    • Hong, David W.;
    • O'Neil, Paul
    Publication type:
    Article
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    Establishment of an in vitro culture system to study the developmental biology of Onchocerca volvulus with implications for anti-Onchocerca drug discovery and screening.

    Published in:
    PLoS Neglected Tropical Diseases, 2021, v. 15, n. 2, p. 1, doi. 10.1371/journal.pntd.0008513
    By:
    • Gandjui, Narcisse V. T.;
    • Njouendou, Abdel J.;
    • Gemeg, Eric N.;
    • Fombad, Fanny F.;
    • Ritter, Manuel;
    • Kien, Chi A.;
    • Chunda, Valerine C.;
    • Fru, Jerome;
    • Esum, Mathias E.;
    • Hübner, Marc P.;
    • Enyong, Peter A.;
    • Hoerauf, Achim;
    • Wanji, Samuel
    Publication type:
    Article
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    Genome-wide transcriptome induced by Porphyromonas gingivalis LPS supports the notion of host-derived periodontal destruction and its association with systemic diseases.

    Published in:
    Innate Immunity, 2016, v. 22, n. 1, p. 72, doi. 10.1177/1753425915616685
    By:
    • Gölz, Lina;
    • Buerfent, Benedikt C.;
    • Hofmann, Andrea;
    • Hübner, Marc P.;
    • Rühl, Heiko;
    • Fricker, Nadine;
    • Schmidt, David;
    • Johannes, Oldenburg;
    • Jepsen, Søren;
    • Deschner, James;
    • Hoerauf, Achim;
    • Nöthen, Markus M.;
    • Schumacher, Johannes;
    • Jäger, Andreas
    Publication type:
    Article
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    A qPCR to quantify Wolbachia from few Onchocerca volvulus microfilariae as a surrogate for adult worm histology in clinical trials of antiwolbachial drugs.

    Published in:
    Parasitology Research, 2022, v. 121, n. 4, p. 1199, doi. 10.1007/s00436-021-07411-5
    By:
    • Schlabe, Stefan;
    • Korir, Patricia;
    • Lämmer, Christine;
    • Landmann, Frederic;
    • Dubben, Bettina;
    • Koschel, Marianne;
    • Albers, Anna;
    • Debrah, Linda Batsa;
    • Debrah, Alexander Yaw;
    • Hübner, Marc P.;
    • Pfarr, Kenneth;
    • Klarmann-Schulz, Ute;
    • Hoerauf, Achim
    Publication type:
    Article
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    Eosinophils Suppress the Migration of T Cells Into the Brain of Plasmodium berghei -Infected Ifnar1<sup>-/-</sup> Mice and Protect Them From Experimental Cerebral Malaria.

    Published in:
    Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.711876
    By:
    • Scheunemann, Johanna F.;
    • Reichwald, Julia J.;
    • Korir, Patricia Jebett;
    • Kuehlwein, Janina M.;
    • Jenster, Lea-Marie;
    • Hammerschmidt-Kamper, Christiane;
    • Lewis, Matthew D.;
    • Klocke, Katrin;
    • Borsche, Max;
    • Schwendt, Kim E.;
    • Soun, Camille;
    • Thiebes, Stephanie;
    • Limmer, Andreas;
    • Engel, Daniel R.;
    • Mueller, Ann-Kristin;
    • Hoerauf, Achim;
    • Hübner, Marc P.;
    • Schumak, Beatrix
    Publication type:
    Article
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    Corallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections.

    Published in:
    PLoS Neglected Tropical Diseases, 2020, v. 14, n. 12, p. 1, doi. 10.1371/journal.pntd.0008930
    By:
    • Schiefer, Andrea;
    • Hübner, Marc P.;
    • Krome, Anna;
    • Lämmer, Christine;
    • Ehrens, Alexandra;
    • Aden, Tilman;
    • Koschel, Marianne;
    • Neufeld, Helene;
    • Chaverra-Muñoz, Lillibeth;
    • Jansen, Rolf;
    • Kehraus, Stefan;
    • König, Gabriele M.;
    • Pogorevc, Domen;
    • Müller, Rolf;
    • Stadler, Marc;
    • Hüttel, Stephan;
    • Hesterkamp, Thomas;
    • Wagner, Karl;
    • Pfarr, Kenneth;
    • Hoerauf, Achim
    Publication type:
    Article
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    Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro.

    Published in:
    PLoS Neglected Tropical Diseases, 2020, v. 14, n. 7, p. 1, doi. 10.1371/journal.pntd.0008427
    By:
    • Hübner, Marc P.;
    • Martin, Coralie;
    • Specht, Sabine;
    • Koschel, Marianne;
    • Dubben, Bettina;
    • Frohberger, Stefan J.;
    • Ehrens, Alexandra;
    • Fendler, Martina;
    • Struever, Dominique;
    • Mitre, Edward;
    • Vallarino-Lhermitte, Nathaly;
    • Gokool, Suzanne;
    • Lustigman, Sara;
    • Schneider, Manfred;
    • Townson, Simon;
    • Hoerauf, Achim;
    • Scandale, Ivan
    Publication type:
    Article
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    S100A8/S100A9 deficiency increases neutrophil activation and protective immune responses against invading infective L3 larvae of the filarial nematode Litomosoides sigmodontis.

    Published in:
    PLoS Neglected Tropical Diseases, 2020, v. 14, n. 2, p. 1, doi. 10.1371/journal.pntd.0008119
    By:
    • Frohberger, Stefan J.;
    • Fercoq, Frederic;
    • Neumann, Anna-Lena;
    • Surendar, Jayagopi;
    • Stamminger, Wiebke;
    • Ehrens, Alexandra;
    • Karunakaran, Indulekha;
    • Remion, Estelle;
    • Vogl, Thomas;
    • Hoerauf, Achim;
    • Martin, Coralie;
    • Hübner, Marc P.
    Publication type:
    Article
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    In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis.

    Published in:
    PLoS Neglected Tropical Diseases, 2020, v. 14, n. 1, p. 1, doi. 10.1371/journal.pntd.0007957
    By:
    • Ehrens, Alexandra;
    • Lunde, Christopher S.;
    • Jacobs, Robert T.;
    • Struever, Dominique;
    • Koschel, Marianne;
    • Frohberger, Stefan J.;
    • Lenz, Franziska;
    • Fendler, Martina;
    • Turner, Joseph D.;
    • Ward, Stephen A.;
    • Taylor, Mark J.;
    • Freund, Yvonne R.;
    • Stefanakis, Rianna;
    • Easom, Eric;
    • Li, Xianfeng;
    • Plattner, Jacob J.;
    • Hoerauf, Achim;
    • Hübner, Marc P.
    Publication type:
    Article
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    The design and development of a study protocol to investigate Onchocerca volvulus, Loa loa and Mansonella perstans-mediated modulation of the metabolic and immunological profile in lean and obese individuals in Cameroon.

    Published in:
    PLoS ONE, 2023, v. 18, n. 6, p. 1, doi. 10.1371/journal.pone.0285689
    By:
    • Lenz, Benjamin;
    • Andrew, Beng Amuam;
    • Ritter, Manuel;
    • Karunakaran, Indulekha;
    • Gandjui, Narcisse Victor Tchamatchoua;
    • Nchang, Lucy Cho;
    • Surendar, Jayagopi;
    • Ebob, Anita Obi Bate;
    • Ehrens, Alexandra;
    • Klarmann-Schulz, Ute;
    • Ricchiuto, Arcangelo;
    • Kuehlwein, Janina M.;
    • Fombad, Fanny Fri;
    • Ngwa, Ambe Marius;
    • Katcho, Tatiana Djikeussi;
    • Hoerauf, Achim;
    • Wanji, Samuel;
    • Hübner, Marc P.
    Publication type:
    Article
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    Filarial extract of Litomosoides sigmodontis induces a type 2 immune response and attenuates plaque development in hyperlipidemic ApoE-knockout mice.

    Published in:
    FASEB Journal, 2019, v. 33, n. 5, p. 6497, doi. 10.1096/fj.201800947RR
    By:
    • Kuehn, Constanze;
    • Miyuki Tauchi;
    • Furtmair, Roman;
    • Urschel, Katharina;
    • Raaz-Schrauder, Dorette;
    • Neumann, Anna-Lena;
    • Frohberger, Stefan J.;
    • Hoerauf, Achim;
    • Regus, Susanne;
    • Lang, Werner;
    • Sagban, Tolga Atilla;
    • Stumpfe, Florian Matthias;
    • Achenbach, Stephan;
    • Hübner, Marc P.;
    • Dietel, Barbara
    Publication type:
    Article
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    Revision of the "Guideline of the German Medical Association on Quality Assurance in Medical Laboratory Examinations – Rili-BAEK".

    Published in:
    Journal of Laboratory Medicine, 2024, v. 48, n. 6, p. 263, doi. 10.1515/labmed-2024-0131
    By:
    • Ahmad-Nejad, Parviz;
    • Bauersfeld, Walter;
    • Baum, Hannsjörg;
    • Behre, Hermann M.;
    • Burkhardt, Ralph;
    • Cassens, Uwe;
    • Ceglarek, Uta;
    • Christmann, Martin;
    • Cremers, Jann-Frederik;
    • Diedrich, Sabine;
    • Döring, Sybille;
    • Gässler, Norbert;
    • Haase, Gerhard;
    • Haselmann, Verena;
    • Hofmann, Jörg;
    • Holdenrieder, Stefan;
    • Hübner, Marc P.;
    • Hunfeld, Klaus-Peter;
    • Huzly, Daniela;
    • Kohlschmidt, Nicolai
    Publication type:
    Article
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    In vivo kinetics of Wolbachia depletion by ABBV-4083 in L. sigmodontis adult worms and microfilariae.

    Published in:
    PLoS Neglected Tropical Diseases, 2019, v. 13, n. 8, p. 1, doi. 10.1371/journal.pntd.0007636
    By:
    • Hübner, Marc P.;
    • Koschel, Marianne;
    • Struever, Dominique;
    • Nikolov, Venelin;
    • Frohberger, Stefan J.;
    • Ehrens, Alexandra;
    • Fendler, Martina;
    • Johannes, Iliana;
    • von Geldern, Thomas W.;
    • Marsh, Kennan;
    • Turner, Joseph D.;
    • Taylor, Mark J.;
    • Ward, Stephen A.;
    • Pfarr, Kenneth;
    • Kempf, Dale J.;
    • Hoerauf, Achim
    Publication type:
    Article
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    Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity.

    Published in:
    PLoS Neglected Tropical Diseases, 2019, v. 13, n. 2, p. 1, doi. 10.1371/journal.pntd.0007159
    By:
    • von Geldern, Thomas W.;
    • Morton, Howard E.;
    • Clark, Rick F.;
    • Brown, Brian S.;
    • Johnston, Kelly L.;
    • Ford, Louise;
    • Specht, Sabine;
    • Carr, Robert A.;
    • Stolarik, Deanne F.;
    • Ma, Junli;
    • Rieser, Matthew J.;
    • Struever, Dominique;
    • Frohberger, Stefan J.;
    • Koschel, Marianne;
    • Ehrens, Alexandra;
    • Turner, Joseph D.;
    • Hübner, Marc P.;
    • Hoerauf, Achim;
    • Taylor, Mark J.;
    • Ward, Stephen A.
    Publication type:
    Article
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    Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds.

    Published in:
    PLoS Neglected Tropical Diseases, 2019, v. 13, n. 1, p. 1, doi. 10.1371/journal.pntd.0006320
    By:
    • Hübner, Marc P.;
    • Ehrens, Alexandra;
    • Koschel, Marianne;
    • Dubben, Bettina;
    • Lenz, Franziska;
    • Frohberger, Stefan J.;
    • Specht, Sabine;
    • Hoerauf, Achim;
    • Quirynen, Ludo;
    • Lachau-Durand, Sophie;
    • Tekle, Fetene;
    • Baeten, Benny;
    • Engelen, Marc;
    • Mackenzie, Charles D.
    Publication type:
    Article