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  • An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans.

    Published in:
    PLoS Neglected Tropical Diseases, 2020, v. 15, n. 8, p. 1, doi. 10.1371/journal.pntd.0008517
    By:
    • Guzman, Meghan A.;
    • Rugel, Anastasia R.;
    • Tarpley, Reid S.;
    • Alwan, Sevan N.;
    • Chevalier, Frédéric D.;
    • Kovalskyy, Dmytro P.;
    • Cao, Xiaohang;
    • Holloway, Stephen P.;
    • Anderson, Timothy J. C.;
    • Taylor, Alexander B.;
    • McHardy, Stanton F.;
    • LoVerde, Philip T.
    Publication type:
    Article

  • Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment.

    Published in:
    PLoS Pathogens, 2019, v. 15, n. 10, p. 1, doi. 10.1371/journal.ppat.1007881
    By:
    • Chevalier, Frédéric D.;
    • Le Clec'h, Winka;
    • McDew-White, Marina;
    • Menon, Vinay;
    • Guzman, Meghan A.;
    • Holloway, Stephen P.;
    • Cao, Xiaohang;
    • Taylor, Alexander B.;
    • Kinung'hi, Safari;
    • Gouvras, Anouk N.;
    • Webster, Bonnie L.;
    • Webster, Joanne P.;
    • Emery, Aidan M.;
    • Rollinson, David;
    • Garba Djirmay, Amadou;
    • Al Mashikhi, Khalid M.;
    • Al Yafae, Salem;
    • Idris, Mohamed A.;
    • Moné, Hélène;
    • Mouahid, Gabriel
    Publication type:
    Article

  • Schistosome Sulfotransferases: Mode of Action, Expression and Localization.

    Published in:
    Pharmaceutics, 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/pharmaceutics14071416
    By:
    • Guzman, Meghan A.;
    • Rugel, Anastasia;
    • Alwan, Sevan N.;
    • Tarpley, Reid;
    • Taylor, Alexander B.;
    • Chevalier, Frédéric D.;
    • Wendt, George R.;
    • Collins III, James J.;
    • Anderson, Timothy J. C.;
    • McHardy, Stanton F.;
    • LoVerde, Philip T.
    Publication type:
    Article