Works by Guthridge, Joel

Results: 53
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    Sjögren's Syndrome Minor Salivary Gland CD4+ Memory T Cells Associate with Glandular Disease Features and Have a Germinal Center T Follicular Helper Transcriptional Profile.

    Published in:
    Journal of Clinical Medicine, 2020, v. 9, n. 7, p. 2164, doi. 10.3390/jcm9072164
    By:
    • Joachims, Michelle L.;
    • Leehan, Kerry M.;
    • Dozmorov, Mikhail G.;
    • Georgescu, Constantin;
    • Pan, Zijian;
    • Lawrence, Christina;
    • Marlin, M. Caleb;
    • Macwana, Susan;
    • Rasmussen, Astrid;
    • Radfar, Lida;
    • Lewis, David M.;
    • Stone, Donald U.;
    • Grundahl, Kiely;
    • Scofield, R. Hal;
    • Lessard, Christopher J.;
    • Wren, Jonathan D.;
    • Thompson, Linda F.;
    • Guthridge, Joel M.;
    • Sivils, Kathy L.;
    • Moore, Jacen S.
    Publication type:
    Article
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    High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership.

    Published in:
    Rheumatology, 2022, v. 61, n. 11, p. 4335, doi. 10.1093/rheumatology/keac067
    By:
    • Carlucci, Philip M;
    • Li, Jessica;
    • Fava, Andrea;
    • Deonaraine, Kristina K;
    • Wofsy, David;
    • James, Judith A;
    • Putterman, Chaim;
    • Diamond, Betty;
    • Davidson, Anne;
    • Fine, Derek M;
    • Monroy-Trujillo, Jose;
    • Atta, Mohamed G;
    • DeJager, Wade;
    • Guthridge, Joel M;
    • Haag, Kristin;
    • Rao, Deepak A;
    • Brenner, Michael B;
    • Lederer, James A;
    • Apruzzese, William;
    • Belmont, H Michael
    Publication type:
    Article
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    Unique Sjögren's syndrome patient subsets defined by molecular features.

    Published in:
    Rheumatology, 2020, v. 59, n. 4, p. 860, doi. 10.1093/rheumatology/kez335
    By:
    • James, Judith A;
    • Guthridge, Joel M;
    • Chen, Hua;
    • Lu, Rufei;
    • Bourn, Rebecka L;
    • Bean, Krista;
    • Munroe, Melissa E;
    • Smith, Miles;
    • Chakravarty, Eliza;
    • Baer, Alan N;
    • Noaiseh, Ghaith;
    • Parke, Ann;
    • Boyle, Karen;
    • Keyes-Elstein, Lynette;
    • Coca, Andreea;
    • Utset, Tammy;
    • Genovese, Mark C;
    • Pascual, Virginia;
    • Utz, Paul J;
    • Holers, V. Michael
    Publication type:
    Article
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    Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus.

    Published in:
    Genome Biology, 2020, v. 21, n. 1, p. N.PAG, doi. 10.1186/s13059-020-02184-z
    By:
    • Raj, Prithvi;
    • Song, Ran;
    • Zhu, Honglin;
    • Riediger, Linley;
    • Jun, Dong-Jae;
    • Liang, Chaoying;
    • Arana, Carlos;
    • Zhang, Bo;
    • Gao, Yajing;
    • Wakeland, Benjamin E.;
    • Dozmorov, Igor;
    • Zhou, Jinchun;
    • Kelly, Jennifer A.;
    • Lauwerys, Bernard R.;
    • Guthridge, Joel M.;
    • Olsen, Nancy J.;
    • Nath, Swapan K.;
    • Pasare, Chandrashekhar;
    • van Oers, Nicolai;
    • Gilkeson, Gary
    Publication type:
    Article
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    Multiple Autoantibodies Display Association with Lymphopenia, Proteinuria, and Cellular Casts in a Large, Ethnically Diverse SLE Patient Cohort.

    Published in:
    Autoimmune Diseases (2090-0422), 2012, p. 1, doi. 10.1155/2012/819634
    By:
    • Lu, Rufei;
    • Robertson, Julie M.;
    • Bruner, Benjamin F.;
    • Guthridge, Joel M.;
    • Neas, Barbara R.;
    • Nath, Swapan K.;
    • Kelly, Jennifer A.;
    • Moser Sivils, Kathy L.;
    • Chakravarty, Eliza F.;
    • Kamen, Diane L.;
    • Gilkeson, Gary S.;
    • Wallace, Daniel J.;
    • Weisman, Michael H.;
    • Hal Scofield, R.;
    • Harley, John B.;
    • James, Judith A.
    Publication type:
    Article
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    Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.

    Published in:
    Nature Genetics, 2011, v. 43, n. 3, p. 253, doi. 10.1038/ng.766
    By:
    • Adrianto, Indra;
    • Feng Wen;
    • Templeton, Amanda;
    • Wiley, Graham;
    • King, Jarrod B.;
    • Lessard, Christopher J.;
    • Bates, Jared S.;
    • Yanqing Hu;
    • Kelly, Jennifer A.;
    • Kaufman, Kenneth M.;
    • Guthridge, Joel M.;
    • Alarcón-Riquelme, Marta E.;
    • Anaya, Juan-Manuel;
    • Sang-Cheol Bae;
    • So-Young Bang;
    • Boackle, Susan A.;
    • Brown, Elizabeth E.;
    • Petri, Michelle A.;
    • Gallant, Caroline;
    • Ramsey-Goldman, Rosalind
    Publication type:
    Article
    13

    A nonsynonymous functional variant in integrin-α<sub>M</sub> (encoded by ITGAM) is associated with systemic lupus erythematosus.

    Published in:
    Nature Genetics, 2008, v. 40, n. 2, p. 152, doi. 10.1038/ng.71
    By:
    • Nath, Swapan K.;
    • Shizhong Han;
    • Kim-Howard, Xana;
    • Kelly, Jennifer A.;
    • Viswanathan, Parvathi;
    • Gilkeson, Gary S.;
    • Wei Chen;
    • Cheng Zhu;
    • McEver, Rodger P.;
    • Kimberly, Robert P.;
    • Alarcón-Riquelme, Marta E.;
    • Vyse, Timothy J.;
    • Quan-Zhen Li;
    • Wakeland, Edward K.;
    • Merrill, Joan T.;
    • James, Judith A.;
    • Kaufman, Kenneth M.;
    • Guthridge, Joel M.;
    • Harley, John B.
    Publication type:
    Article
    14

    Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

    Published in:
    Nature Genetics, 2008, v. 40, n. 2, p. 204, doi. 10.1038/ng.81
    By:
    • Harley, John B.;
    • Alarcón-Riquelme, Marta E.;
    • Criswell, Lindsey A.;
    • Jacob, Chaim O.;
    • Kimberly, Robert P.;
    • Moser, Kathy L.;
    • Tsao, Betty P.;
    • Vyse, Timothy J.;
    • Langefeld, Carl D.;
    • Nath, Swapan K.;
    • Guthridge, Joel M.;
    • Cobb, Beth L.;
    • Mirel, Daniel B.;
    • Marion, Miranda C.;
    • Williams, Adrienne H.;
    • Divers, Jasmin;
    • Wei Wang;
    • Frank, Summer G.;
    • Namjou, Bahram;
    • Gabriel, Stacey B.
    Publication type:
    Article
    15

    Trans-Ancestral Studies Fine Map the SLE-Susceptibility Locus <i>TNFSF4</i>.

    Published in:
    PLoS Genetics, 2013, v. 9, n. 7, p. 1, doi. 10.1371/journal.pgen.1003554
    By:
    • Manku, Harinder;
    • Langefeld, Carl D.;
    • Guerra, Sandra G.;
    • Malik, Talat H.;
    • Alarcon-Riquelme, Marta;
    • Anaya, Juan-Manuel;
    • Bae, Sang-Cheol;
    • Boackle, Susan A.;
    • Brown, Elizabeth E.;
    • Criswell, Lindsey A.;
    • Freedman, Barry I.;
    • Gaffney, Patrick M.;
    • Gregersen, Peter A.;
    • Guthridge, Joel M.;
    • Han, Sang-Hoon;
    • Harley, John B.;
    • Jacob, Chaim O.;
    • James, Judith A.;
    • Kamen, Diane L.;
    • Kaufman, Kenneth M.
    Publication type:
    Article
    16

    Ethical and Practical Issues Associated with Aggregating Databases.

    Published in:
    PLoS Medicine, 2008, v. 5, n. 9, p. e190, doi. 10.1371/journal.pmed.0050190
    By:
    • Karp, David R.;
    • Carlin, Shelley;
    • Cook-Deegan, Robert;
    • Ford, Daniel E.;
    • Geller, Gail;
    • Glass, David N.;
    • Greely, Hank;
    • Guthridge, Joel;
    • Kahn, Jeffrey;
    • Kaslow, Richard;
    • Kraft, Cheryl;
    • MacQueen, Kathleen;
    • Malin, Bradley;
    • Scheuerman, Richard H.;
    • Sugarman, Jeremy
    Publication type:
    Article
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    Immune profiling in Puerto Rican injection drug users with and without HIV-1 infection.

    Published in:
    Journal of Leukocyte Biology, 2023, v. 114, n. 2, p. 142, doi. 10.1093/jleuko/qiad045
    By:
    • Bennett, Sydney J;
    • Davila, Carmen Ana;
    • Reyes, Zahiraliz;
    • Valentín-Acevedo, Aníbal;
    • Gocchi Carrasco, Kim;
    • Abadie, Roberto;
    • Marlin, M Caleb;
    • Beel, Marci;
    • Chapple, Andrew G;
    • Fernando, Samodha;
    • Guthridge, Joel M;
    • Chiou, Kathy S;
    • Dombrowski, Kirk;
    • West, John T;
    • Wood, Charles
    Publication type:
    Article
    20

    Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.

    Published in:
    Nature Genetics, 2013, v. 45, n. 11, p. 1284, doi. 10.1038/ng.2792
    By:
    • Lessard, Christopher J;
    • Li, He;
    • Adrianto, Indra;
    • Ice, John A;
    • Rasmussen, Astrid;
    • Grundahl, Kiely M;
    • Kelly, Jennifer A;
    • Dozmorov, Mikhail G;
    • Miceli-Richard, Corinne;
    • Bowman, Simon;
    • Lester, Sue;
    • Eriksson, Per;
    • Eloranta, Maija-Leena;
    • Brun, Johan G;
    • Gøransson, Lasse G;
    • Harboe, Erna;
    • Guthridge, Joel M;
    • Kaufman, Kenneth M;
    • Kvarnström, Marika;
    • Jazebi, Helmi
    Publication type:
    Article
    21

    Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.

    Published in:
    Nature Genetics, 2013, v. 45, n. 6, p. 664, doi. 10.1038/ng.2614
    By:
    • Hinks, Anne;
    • Cobb, Joanna;
    • Marion, Miranda C;
    • Prahalad, Sampath;
    • Sudman, Marc;
    • Bowes, John;
    • Martin, Paul;
    • Comeau, Mary E;
    • Sajuthi, Satria;
    • Andrews, Robert;
    • Brown, Milton;
    • Chen, Wei-Min;
    • Concannon, Patrick;
    • Deloukas, Panos;
    • Edkins, Sarah;
    • Eyre, Stephen;
    • Gaffney, Patrick M;
    • Guthery, Stephen L;
    • Guthridge, Joel M;
    • Hunt, Sarah E
    Publication type:
    Article
    22

    Obexelimab in Systemic Lupus Erythematosus With Exploration of Response Based on Gene Pathway Co‐Expression Patterns: A Double‐Blind, Randomized, Placebo‐Controlled, Phase 2 Trial.

    Published in:
    Arthritis & Rheumatology, 2023, v. 75, n. 12, p. 2185, doi. 10.1002/art.42652
    By:
    • Merrill, Joan T.;
    • Guthridge, Joel;
    • Smith, Miles;
    • June, Joshua;
    • Koumpouras, Fotios;
    • Machua, Wambui;
    • Askanase, Anca;
    • Khosroshahi, Arezou;
    • Sheikh, Saira Z.;
    • Rathi, Gaurav;
    • Burington, Bart;
    • Foster, Paul;
    • Matijevic, Mark;
    • Arora, Sujata;
    • Wang, Xiaodong;
    • Gao, Minggeng;
    • Wax, Stephen;
    • James, Judith A.;
    • Zack, Debra J.
    Publication type:
    Article
    23

    A Flare Risk Index Informed by Select Immune Mediators in Systemic Lupus Erythematosus.

    Published in:
    Arthritis & Rheumatology, 2023, v. 75, n. 5, p. 723, doi. 10.1002/art.42389
    By:
    • Munroe, Melissa E.;
    • Blankenship, Derek;
    • DeFreese, Daniele;
    • Purushothaman, Mohan;
    • DeJager, Wade;
    • Macwana, Susan;
    • Guthridge, Joel M.;
    • Kamp, Stan;
    • Redinger, Nancy;
    • Aberle, Teresa;
    • Chakravarty, Eliza F.;
    • Arriens, Cristina;
    • Li, Yanfeng;
    • Zeng, Hu;
    • McCarthy‐Fruin, Kathleen A.;
    • Osei‐Onomahm, Shirley‐Ann;
    • Thanarajasingam, Uma;
    • James, Judith A.;
    • Jupe, Eldon
    Publication type:
    Article
    24

    Lupus Susceptibility Region Containing CDKN1B rs34330 Mechanistically Influences Expression and Function of Multiple Target Genes, Also Linked to Proliferation and Apoptosis.

    Published in:
    Arthritis & Rheumatology, 2021, v. 73, n. 12, p. 2303, doi. 10.1002/art.41799
    By:
    • Singh, Bhupinder;
    • Maiti, Guru P.;
    • Zhou, Xujie;
    • Fazel‐Najafabadi, Mehdi;
    • Bae, Sang‐Cheol;
    • Sun, Celi;
    • Terao, Chikashi;
    • Okada, Yukinori;
    • Heng Chua, Kek;
    • Kochi, Yuta;
    • Guthridge, Joel M.;
    • Zhang, Hong;
    • Weirauch, Matthew;
    • James, Judith A.;
    • Harley, John B.;
    • Varshney, Gaurav K.;
    • Looger, Loren L.;
    • Nath, Swapan K.
    Publication type:
    Article
    25

    Clinical Efficacy and Safety of Baminercept, a Lymphotoxin β Receptor Fusion Protein, in Primary Sjögren's Syndrome.

    Published in:
    Arthritis & Rheumatology, 2018, v. 70, n. 9, p. 1470, doi. 10.1002/art.40513
    By:
    • St.Clair, E. William;
    • Baer, Alan N.;
    • Wei, Chungwen;
    • Noaiseh, Ghaith;
    • Parke, Anne;
    • Coca, Andreea;
    • Utset, Tammy O.;
    • Genovese, Mark C.;
    • Wallace, Daniel J.;
    • McNamara, James;
    • Boyle, Karen;
    • Keyes‐Elstein, Lynette;
    • Browning, Jeffrey L.;
    • Franchimont, Nathalie;
    • Smith, Kira;
    • Guthridge, Joel M.;
    • Sanz, Ignacio;
    • James, Judith A.;
    • the Autoimmunity Centers of Excellence
    Publication type:
    Article
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    Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features.

    Published in:
    Arthritis & Rheumatology, 2017, v. 69, n. 3, p. 630, doi. 10.1002/art.40004
    By:
    • Munroe, Melissa E.;
    • Young, Kendra A.;
    • Kamen, Diane L.;
    • Guthridge, Joel M.;
    • Niewold, Timothy B.;
    • Costenbader, Karen H.;
    • Weisman, Michael H.;
    • Ishimori, Mariko L.;
    • Wallace, Daniel J.;
    • Gilkeson, Gary S.;
    • Karp, David R.;
    • Harley, John B.;
    • Norris, Jill M.;
    • James, Judith A.
    Publication type:
    Article
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    PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes.

    Published in:
    PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0069404
    By:
    • Namjou, Bahram;
    • Kim-Howard, Xana;
    • Sun, Celi;
    • Adler, Adam;
    • Chung, Sharon A.;
    • Kaufman, Kenneth M.;
    • Kelly, Jennifer A.;
    • Glenn, Stuart B.;
    • Guthridge, Joel M.;
    • Scofield, Robert H.;
    • Kimberly, Robert P.;
    • Brown, Elizabeth E.;
    • Alarcón, Graciela S.;
    • Edberg, Jeffrey C.;
    • Kim, Jae-Hoon;
    • Choi, Jiyoung;
    • Ramsey-Goldman, Rosalind;
    • Petri, Michelle A.;
    • Reveille, John D.;
    • Vilá, Luis M.
    Publication type:
    Article
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    Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.

    Published in:
    PLoS Genetics, 2017, v. 13, n. 6, p. 1, doi. 10.1371/journal.pgen.1006820
    By:
    • Li, He;
    • Reksten, Tove Ragna;
    • Ice, John A.;
    • Kelly, Jennifer A.;
    • Adrianto, Indra;
    • Rasmussen, Astrid;
    • Wang, Shaofeng;
    • He, Bo;
    • Grundahl, Kiely M.;
    • Glenn, Stuart B.;
    • Miceli-Richard, Corinne;
    • Bowman, Simon;
    • Lester, Sue;
    • Eriksson, Per;
    • Eloranta, Maija-Leena;
    • Brun, Johan G.;
    • Gøransson, Lasse G.;
    • Harboe, Erna;
    • Guthridge, Joel M.;
    • Kaufman, Kenneth M.
    Publication type:
    Article
    47

    Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus.

    Published in:
    Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.881332
    By:
    • Vanderlinden, Lauren A.;
    • Bemis, Elizabeth A.;
    • Seifert, Jennifer;
    • Guthridge, Joel M.;
    • Young, Kendra A.;
    • Demoruelle, Mary Kristen;
    • Feser, Marie;
    • DeJager, Wade;
    • Macwana, Susan;
    • Mikuls, Ted R.;
    • O'Dell, James R.;
    • Weisman, Michael H.;
    • Buckner, Jane;
    • Keating, Richard M.;
    • Gaffney, Patrick M.;
    • Kelly, Jennifer A.;
    • Langefeld, Carl D.;
    • Deane, Kevin D.;
    • James, Judith A.;
    • Holers, Vernon Michael
    Publication type:
    Article
    48

    Pre-Clinical Autoimmunity in Lupus Relatives: Self-Reported Questionnaires and Immune Dysregulation Distinguish Relatives Who Develop Incomplete or Classified Lupus From Clinically Unaffected Relatives and Unaffected, Unrelated Individuals.

    Published in:
    Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.866181
    By:
    • Munroe, Melissa E.;
    • Young, Kendra A.;
    • Guthridge, Joel M.;
    • Kamen, Diane L.;
    • Gilkeson, Gary S.;
    • Weisman, Michael H.;
    • Ishimori, Mariko L.;
    • Wallace, Daniel J.;
    • Karp, David R.;
    • Harley, John B.;
    • Norris, Jill M.;
    • James, Judith A.
    Publication type:
    Article
    49

    Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations.

    Published in:
    Human Molecular Genetics, 2014, v. 23, n. 6, p. 1656
    By:
    • Kim-Howard, Xana;
    • Sun, Celi;
    • Molineros, Julio E.;
    • Maiti, Amit K.;
    • Chandru, Hema;
    • Adler, Adam;
    • Wiley, Graham B.;
    • Kaufman, Kenneth M.;
    • Kottyan, Leah;
    • Guthridge, Joel M.;
    • Rasmussen, Astrid;
    • Kelly, Jennifer;
    • Sánchez, Elena;
    • Raj, Prithvi;
    • Li, Quan-Zhen;
    • Bang, So-Young;
    • Lee, Hye-Soon;
    • Kim, Tae-Hwan;
    • Kang, Young Mo;
    • Suh, Chang-Hee
    Publication type:
    Article
    50

    Evaluation of imputation-based association in and around the integrin-α-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).

    Published in:
    Human Molecular Genetics, 2009, v. 18, n. 6, p. 1171, doi. 10.1093/hmg/ddp007
    By:
    • Han, Shizhong;
    • Kim-Howard, Xana;
    • Deshmukh, Harshal;
    • Kamatani, Yoichiro;
    • Viswanathan, Parvathi;
    • Guthridge, Joel M.;
    • Thomas, Kenaz;
    • Kaufman, Kenneth M.;
    • Ojwang, Joshua;
    • Rojas-Villarraga, Adriana;
    • Baca, Vicente;
    • Orozco, Lorena;
    • Rhodes, Benjamin;
    • Choi, Chan-Bum;
    • Gregersen, Peter K.;
    • Merrill, Joan T.;
    • James, Judith A.;
    • Gaffney, Patrick M.;
    • Moser, Kathy L.;
    • Jacob, Chaim O.
    Publication type:
    Article