Works by Guthke, Reinhard

Results: 55

Rheumatoid arthritis, a complex multifactorial disease: On the way toward individualized medicine.

Published in:

Medicinal Research Reviews, 2006, v. 26, n. 1, p. 63, doi. 10.1002/med.20045

By:

Glocker, Michael O.;
Guthke, Reinhard;
Kekow, Jörn;
Thiesen, Hans-Jürgen

Publication type:

Article

FungiFun2: a comprehensive online resource for systematic analysis of gene lists from fungal species.

Published in:

Bioinformatics, 2015, v. 31, n. 3, p. 445, doi. 10.1093/bioinformatics/btu627

By:

Priebe, Steffen;
Kreisel, Christian;
Horn, Fabian;
Guthke, Reinhard;
Linde, Jörg

Publication type:

Article

Heterogeneous expression of suppressor of cytokine signalling 2 (SOCS-2) in liver tissue.

Published in:

Journal of Anatomy, 2009, v. 215, n. 2, p. 176, doi. 10.1111/j.1469-7580.2009.01085.x

By:

Zellmer, Sebastian;
Sickinger, Stephan;
Schmidt-Heck, Wolfgang;
Guthke, Reinhard;
Gebhardt, Rolf

Publication type:

Article

Novel application of multi-stimuli network inference to synovial fibroblasts of rheumatoid arthritis patients.

Published in:

BMC Medical Genomics, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1755-8794-7-40

By:

Kupfer, Peter;
Huber, René;
Weber, Michael;
Vlaic, Sebastian;
Häupl, Thomas;
Koczan, Dirk;
Guthke, Reinhard;
Kinne, Raimund W.

Publication type:

Article

Batch correction of microarray data substantially improves the identification of genes differentially expressed in Rheumatoid Arthritis and Osteoarthritis.

Published in:

BMC Medical Genomics, 2012, v. 5, n. 1, p. 23, doi. 10.1186/1755-8794-5-23

By:

Kupfer, Peter;
Guthke, Reinhard;
Pohlers, Dirk;
Huber, Rene;
Koczan, Dirk;
Kinne, Raimund W

Publication type:

Article

Hormetic effect of rotenone in primary human fibroblasts.

Published in:

Immunity & Ageing, 2015, v. 12, n. 1, p. 1, doi. 10.1186/s12979-015-0038-8

By:

Marthandan, Shiva;
Priebe, Steffen;
Groth, Marco;
Guthke, Reinhard;
Platzer, Matthias;
Hemmerich, Peter;
Diekmann, Stephan

Publication type:

Article

Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus reveals novel insights into the genome and MpkA dependent gene expression.

Published in:

BMC Genomics, 2012, v. 13, n. 1, p. 519, doi. 10.1186/1471-2164-13-519

By:

Müller, Sebastian;
Baldin, Clara;
Groth, Marco;
Guthke, Reinhard;
Kniemeyer, Olaf;
Brakhage, Axel A.;
Valiante, Vito

Publication type:

Article

Integrative analysis of the heat shock response in Aspergillus fumigatus.

Published in:

BMC Genomics, 2010, v. 11, p. 1, doi. 10.1186/1471-2164-11-32

By:

Albrecht, Daniela;
Guthke, Reinhard;
Brakhage, Axel A;
Kniemeyer, Olaf

Publication type:

Article

Dynamic network reconstruction from gene expression data applied to immune response during bacterial infection.

Published in:

Bioinformatics, 2005, v. 21, n. 8, p. 1626, doi. 10.1093/bioinformatics/bti226

By:

Reinhard Guthke;
Ulrich Möller;
Martin Hoffmann;
Frank Thies;
Susanne Töpfer

Publication type:

Article

Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/731938

By:

Marthandan, Shiva;
Priebe, Steffen;
Baumgart, Mario;
Groth, Marco;
Cellerino, Alessandro;
Guthke, Reinhard;
Hemmerich, Peter;
Diekmann, Stephan

Publication type:

Article

Increased Expression of RUNX1 in Liver Correlates with NASH Activity Score in Patients with Non-Alcoholic Steatohepatitis (NASH).

Published in:

Cells (2073-4409), 2019, v. 8, n. 10, p. 1277, doi. 10.3390/cells8101277

By:

Kaur, Savneet;
Rawal, Preety;
Siddiqui, Hamda;
Rohilla, Sumati;
Sharma, Shvetank;
Tripathi, Dinesh M;
Baweja, Sukriti;
Hassan, Mohsin;
Vlaic, Sebastian;
Guthke, Reinhard;
Thomas, Maria;
Dayoub, Rania;
Bihari, Chaggan;
Sarin, Shiv K.;
Weiss, Thomas S.

Publication type:

Article

Global epithelial cell transcriptional responses reveal Streptococcus pyogenes Fas regulator activity association with bacterial aggressiveness.

Published in:

Cellular Microbiology, 2005, v. 7, n. 9, p. 1237, doi. 10.1111/j.1462-5822.2005.00548.x

By:

Klenk, Michael;
Koczan, Dirk;
Guthke, Reinhard;
Nakata, Masanobu;
Thiesen, Hans-Jürgen;
Podbielski, Andreas;
Kreikemeyer, Bernd

Publication type:

Article

Regulatory Networks Controlling Nitrogen Sensing and Uptake in <i>Candida albicans</i>.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0092734

By:

Ramachandra, Shruthi;
Linde, Jörg;
Brock, Matthias;
Guthke, Reinhard;
Hube, Bernhard;
Brunke, Sascha

Publication type:

Article

Extension of Life Span by Impaired Glucose Metabolism in <i>Caenorhabditis elegans</i> Is Accompanied by Structural Rearrangements of the Transcriptomic Network.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077776

By:

Priebe, Steffen;
Menzel, Uwe;
Zarse, Kim;
Groth, Marco;
Platzer, Matthias;
Ristow, Michael;
Guthke, Reinhard

Publication type:

Article

Automated Image Analysis of the Host-Pathogen Interaction between Phagocytes and Aspergillus fumigatus.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019591

By:

Mech, Franziska;
Thywißen, Andreas;
Guthke, Reinhard;
Brakhage, Axel A.;
Figge, Marc Thilo

Publication type:

Article

Optimal regulatory strategies for metabolic pathways in Escherichia coli depending on protein costs.

Published in:

Molecular Systems Biology, 2011, v. 7, n. 1, p. 1, doi. 10.1038/msb.2011.46

By:

Wessely, Frank;
Bartl, Martin;
Guthke, Reinhard;
Li, Pu;
Schuster, Stefan;
Kaleta, Christoph

Publication type:

Article

Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease.

Published in:

Archives of Toxicology, 2020, v. 94, n. 1, p. 205, doi. 10.1007/s00204-019-02630-3

By:

Campos, Gisela;
Schmidt-Heck, Wolfgang;
De Smedt, Jonathan;
Widera, Agata;
Ghallab, Ahmed;
Pütter, Larissa;
González, Daniela;
Edlund, Karolina;
Cadenas, Cristina;
Marchan, Rosemarie;
Guthke, Reinhard;
Verfaillie, Catherine;
Hetz, Claudio;
Sachinidis, Agapios;
Braeuning, Albert;
Schwarz, Michael;
Weiß, Thomas S.;
Banhart, Benjamin K.;
Hoek, Jan;
Vadigepalli, Rajanikanth

Publication type:

Article

The novel globin protein fungoglobin is involved in low oxygen adaptation of A spergillus fumigatus.

Published in:

Molecular Microbiology, 2014, v. 93, n. 3, p. 539, doi. 10.1111/mmi.12679

By:

Hillmann, Falk;
Linde, Jörg;
Beckmann, Nicola;
Cyrulies, Michael;
Strassburger, Maria;
Heinekamp, Thorsten;
Haas, Hubertus;
Guthke, Reinhard;
Kniemeyer, Olaf;
Brakhage, Axel A.

Publication type:

Article

DATA- AND KNOWLEDGE-BASED MODELING OF GENE REGULATORY NETWORKS: AN UPDATE.

Published in:

EXCLI Journal, 2015, v. 14, p. 346, doi. 10.17179/excli2015-168

By:

Linde, Jörg;
Schulze, Sylvie;
Henkel, Sebastian G.;
Guthke, Reinhard

Publication type:

Article

DeltaMS: a tool to track isotopologues in GC- and LC-MS data.

Published in:

Metabolomics, 2018, v. 14, n. 4, p. 1, doi. 10.1007/s11306-018-1336-x

By:

Baumeister, Tim U. H.;
Ueberschaar, Nico;
Schmidt-Heck, Wolfgang;
Mohr, J. Frieder;
Deicke, Michael;
Wichard, Thomas;
Guthke, Reinhard;
Pohnert, Georg

Publication type:

Article

Dynamic modelling of microRNA regulation during mesenchymal stem cell differentiation.

Published in:

BMC Systems Biology, 2013, v. 7, n. 1, p. 1, doi. 10.1186/1752-0509-7-124

By:

Weber, Michael;
Sotoca, Ana M.;
Kupfer, Peter;
Guthke, Reinhard;
van Zoelen, Everardus J.

Publication type:

Article

Inference of dynamical gene-regulatory networks based on time-resolved multi-stimuli multi-experiment data applying NetGenerator V2.0.

Published in:

BMC Systems Biology, 2013, v. 7, n. 1, p. 1, doi. 10.1186/1752-0509-7-1

By:

Weber, Michael;
Henkel, Sebastian G.;
Vlaic, Sebastian;
Guthke, Reinhard;
Zoelen, Everardus J van;
Driesch, Dominik

Publication type:

Article

The extended TILAR approach: a novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes.

Published in:

BMC Systems Biology, 2012, v. 6, n. 1, p. 1, doi. 10.1186/1752-0509-6-147

By:

Vlaic, Sebastian;
Schmidt-Heck, Wolfgang;
Matz-Soja, Madlen;
Marbach, Eugenia;
Linde, Jörg;
Meyer-Baese, Anke;
Zellmer, Sebastian;
Guthke, Reinhard;
Gebhardt, Rolf

Publication type:

Article

Integrative inference of gene-regulatory networks in Escherichia coli using information theoretic concepts and sequence analysis.

Published in:

BMC Systems Biology, 2010, v. 4, p. 116, doi. 10.1186/1752-0509-4-116

By:

Kaleta, Christoph;
Göhler, Anna;
Schuster, Stefan;
Jahreis, Knut;
Guthke, Reinhard;
Nikolajewa, Swetlana

Publication type:

Article

Regulatory network modelling of iron acquisition by a fungal pathogen in contact with epithelial cells.

Published in:

BMC Systems Biology, 2010, v. 4, p. 148, doi. 10.1186/1752-0509-4-148

By:

Linde, Jörg;
Wilson, Duncan;
Hube, Bernhard;
Guthke, Reinhard

Publication type:

Article

Data-based Reconstruction of Gene Regulatory Networks of Fungal Pathogens.

Published in:

Frontiers in Microbiology, 2016, p. 1, doi. 10.3389/fmicb.2016.00570

By:

Guthke, Reinhard;
Gerber, Silvia;
Conrad, Theresia;
Vlaic, Sebastian;
Shelest, Ekaterina;
Linde, Jörg;
Durmuş, Saliha;
Çakır, Tunahan;
Seviigen, F. E.

Publication type:

Article

How to Predict Molecular Interactions between Species?

Published in:

Frontiers in Microbiology, 2016, p. 1, doi. 10.3389/fmicb.2016.00442

By:

Schulze, Sylvie;
Schleicher, Jana;
Guthke, Reinhard;
Linde, Jörg

Publication type:

Article

Genome-Wide Expression Profiling Reveals S100B as Biomarker for Invasive Aspergillosis.

Published in:

Frontiers in Microbiology, 2016, p. 1, doi. 10.3389/fmicb.2016.00320

By:

Dix, Andreas;
Czakai, Kristin;
Springer, Jan;
Fliesser, Mirjam;
Bonin, Michael;
Guthke, Reinhard;
Schmitt, Anna L.;
Einsele, Hermann;
Linde, Jörg;
Löffler, Jürgen

Publication type:

Article

Editorial: Computational Systems Biology of Pathogen-Host Interactions.

Published in:

2016

By:

Durmuş, Saliha;
Çakır, Tunahan;
Guthke, Reinhard

Publication type:

Editorial

A review on computational systems biology of pathogen-host interactions.

Published in:

Frontiers in Microbiology, 2015, p. 1, doi. 10.3389/fmicb.2015.00235

By:

Durmuş, Saliha;
Çakır, Tunahan;
Özgür, Arzucan;
Guthke, Reinhard

Publication type:

Article

Biomarker-based classification of bacterial and fungal whole-blood infections in a genome-wide expression study.

Published in:

Frontiers in Microbiology, 2015, v. 6, p. 1, doi. 10.3389/fmicb.2015.00171

By:

Dix, Andreas;
Guthke, Reinhard;
Linde, Jörg;
Hünniger, Kerstin;
Weber, Michael;
Kurzai, Oliver

Publication type:

Article

Computational prediction of molecular pathogen-host interactions based on dual transcriptome data.

Published in:

Frontiers in Microbiology, 2015, v. 6, p. 1, doi. 10.3389/fmicb.2015.00065

By:

Schulze, Sylvie;
Henkel, Sebastian G.;
Driesch, Dominik;
Guthke, Reinhard;
Linde, Jörg

Publication type:

Article

MS characterization of apheresis samples from rheumatoid arthritis patients for the improvement of immunoadsorption therapy - a pilot study.

Published in:

Proteomics - Clinical Applications, 2009, v. 3, n. 7, p. 797, doi. 10.1002/prca.200800232

By:

Kienbaum, Mike;
Koy, Cornelia;
Montgomery, Helen V.;
Drynda, Susanne;
Lorenz, Peter;
Illges, Harald;
Tanaka, Koichi;
Kekow, Joern;
Guthke, Reinhard;
Thiesen, Hans-Juergen;
Glocker, Michael O.

Publication type:

Article

Cross-hybridizations - corrupting and enhancing microarray probe designs.

Published in:

Biomedical Engineering / Biomedizinische Technik, 2012, v. 57, n. S1, p. 1, doi. 10.1515/bmt-2012-4226

By:

Horn, Fabian;
Guthke, Reinhard

Publication type:

Article

In Silico Evidence for Gluconeogenesis from Fatty Acids in Humans.

Published in:

PLoS Computational Biology, 2011, v. 7, n. 7, p. 1, doi. 10.1371/journal.pcbi.1002116

By:

Kaleta, Christoph;
de Figueiredo, Luís F.;
Werner, Sarah;
Guthke, Reinhard;
Ristow, Michael;
Schuster, Stefan

Publication type:

Article

Missing values in gel-based proteomics.

Published in:

Proteomics, 2010, v. 10, n. 6, p. 1202, doi. 10.1002/pmic.200800576

By:

Albrecht, Daniela;
Kniemeyer, Olaf;
Brakhage, Axel A.;
Guthke, Reinhard

Publication type:

Article

Two-dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus.

Published in:

Proteomics, 2009, v. 9, n. 5, p. 1407, doi. 10.1002/pmic.200800394

By:

Vödisch, Martin;
Albrecht, Daniela;
Leßing, Franziska;
Schmidt, André D.;
Winkler, Robert;
Guthke, Reinhard;
Brakhage, Axel A.;
Kniemeyer, Olaf

Publication type:

Article

4-Hydroxyphenylglycine biosynthesis in Herpetosiphon aurantiacus: a case of gene duplication and catalytic divergence.

Published in:

Archives of Microbiology, 2012, v. 194, n. 6, p. 557, doi. 10.1007/s00203-012-0789-y

By:

Kastner, Stephan;
Müller, Sebastian;
Natesan, Lavanya;
König, Gabriele;
Guthke, Reinhard;
Nett, Markus

Publication type:

Article

Verticillium dahliae-Arabidopsis Interaction Causes Changes in Gene Expression Profiles and Jasmonate Levels on Different Time Scales.

Published in:

Frontiers in Microbiology, 2018, p. 1, doi. 10.3389/fmicb.2018.00217

By:

Scholz, Sandra S.;
Schmidt-Heck, Wolfgang;
Guthke, Reinhard;
Furch, Alexandra C. U.;
Reichelt, Michael;
Gershenzon, Jonathan;
Oelmüller, Ralf

Publication type:

Article

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.

Published in:

Nature Communications, 2015, v. 6, n. 12, p. 10043, doi. 10.1038/ncomms10043

By:

Mansfeld, Johannes;
Urban, Nadine;
Priebe, Steffen;
Groth, Marco;
Frahm, Christiane;
Hartmann, Nils;
Gebauer, Juliane;
Ravichandran, Meenakshi;
Dommaschk, Anne;
Schmeisser, Sebastian;
Kuhlow, Doreen;
Monajembashi, Shamci;
Bremer-Streck, Sibylle;
Hemmerich, Peter;
Kiehntopf, Michael;
Zamboni, Nicola;
Englert, Christoph;
Guthke, Reinhard;
Kaleta, Christoph;
Platzer, Matthias

Publication type:

Article

D-Glucosamine supplementation extends life span of nematodes and of ageing mice.

Published in:

Nature Communications, 2014, v. 5, n. 4, p. 3563, doi. 10.1038/ncomms4563

By:

Weimer, Sandra;
Priebs, Josephine;
Kuhlow, Doreen;
Groth, Marco;
Priebe, Steffen;
Mansfeld, Johannes;
Merry, Troy L.;
Dubuis, Sébastien;
Laube, Beate;
Pfeiffer, Andreas F.;
Schulz, Tim J.;
Guthke, Reinhard;
Platzer, Matthias;
Zamboni, Nicola;
Zarse, Kim;
Ristow, Michael

Publication type:

Article

Facing the challenges of multiscale modelling of bacterial and fungal pathogen-host interactions.

Published in:

Briefings in Functional Genomics, 2017, v. 16, n. 2, p. 57, doi. 10.1093/bfgp/elv064

By:

Schleicher, Jana;
Conrad, Theresia;
Gustafsson, Mika;
Cedersund, Gunnar;
Guthke, Reinhard;
Linde, Jörg

Publication type:

Article

Network Modeling Reveals Cross Talk of MAP Kinases during Adaptation to Caspofungin Stress in Aspergillus fumigatus.

Published in:

PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0136932

By:

Altwasser, Robert;
Baldin, Clara;
Weber, Jakob;
Guthke, Reinhard;
Kniemeyer, Olaf;
Brakhage, Axel A.;
Linde, Jörg;
Valiante, Vito

Publication type:

Article

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.

Published in:

Nature Chemical Biology, 2013, v. 9, n. 11, p. 693, doi. 10.1038/nchembio.1352

By:

Schmeisser, Kathrin;
Mansfeld, Johannes;
Kuhlow, Doreen;
Weimer, Sandra;
Priebe, Steffen;
Heiland, Ines;
Birringer, Marc;
Groth, Marco;
Segref, Alexandra;
Kanfi, Yariv;
Price, Nathan L;
Schmeisser, Sebastian;
Schuster, Stefan;
Pfeiffer, Andreas F H;
Guthke, Reinhard;
Platzer, Matthias;
Hoppe, Thorsten;
Cohen, Haim Y;
Zarse, Kim;
Sinclair, David A

Publication type:

Article

Specific and Novel microRNAs Are Regulated as Response to Fungal Infection in Human Dendritic Cells.

Published in:

Frontiers in Microbiology, 2017, v. 8, p. 1, doi. 10.3389/fmicb.2017.00270

By:

Dix, Andreas;
Czakai, Kristin;
Leonhardt, Ines;
Schäferhoff, Karin;
Bonin, Michael;
Guthke, Reinhard;
Einsele, Hermann;
Kurzai, Oliver;
Löffler, Jürgen;
Linde, Jörg

Publication type:

Article

Differential Biphasic Transcriptional Host Response Associated with Coevolution of Hemagglutinin Quasispecies of Influenza A Virus.

Published in:

Frontiers in Microbiology, 2016, p. 1, doi. 10.3389/fmicb.2016.01167

By:

Manchanda, Himanshu;
Seide, Nora;
Blaess, Markus F.;
Claus, Ralf A.;
Linde, Joerg;
Slevogt, Hortense;
Sauerbrei, Andreas;
Guthke, Reinhard;
Schmidtke, Michaela;
McAuley, Julie;
Fabrizio, Thomas Paul

Publication type:

Article

Dietary.

Published in:

Molecular Nutrition & Food Research, 2011, v. 55, n. 3, p. 419, doi. 10.1002/mnfr.201000293

By:

Keller, Janine;
Ringseis, Robert;
Priebe, Steffen;
Guthke, Reinhard;
Kluge, Holger;
Eder, Klaus

Publication type:

Article

Cadmium, cobalt and lead cause stress response, cell cycle deregulation and increased steroid as well as xenobiotic metabolism in primary normal human bronchial epithelial cells which is coordinated by at least nine transcription factors.

Published in:

Archives of Toxicology, 2008, v. 82, n. 8, p. 513, doi. 10.1007/s00204-008-0331-9

By:

Glahn, Felix;
Schmidt-Heck, Wolfgang;
Zellmer, Sebastian;
Guthke, Reinhard;
Wiese, Jan;
Golka, Klaus;
Hergenröder, Roland;
Degen, Gisela H.;
Lehmann, Thomas;
Hermes, Matthias;
Schormann, Wiebke;
Brulport, Marc;
Bauer, Alexander;
Bedawy, Essam;
Gebhardt, Rolf;
Hengstler, Jan G.;
Foth, Heidi

Publication type:

Article

Candida albicans infection leads to barrier breakdown and a MAPK/NF-κB mediated stress response in the intestinal epithelial cell line C2BBe1.

Published in:

Cellular Microbiology, 2016, v. 18, n. 7, p. 889, doi. 10.1111/cmi.12566

By:

Böhringer, Michael;
Pohlers, Susann;
Schulze, Sylvie;
Albrecht‐Eckardt, Daniela;
Piegsa, Judith;
Weber, Michael;
Martin, Ronny;
Hünniger, Kerstin;
Linde, Jörg;
Guthke, Reinhard;
Kurzai, Oliver

Publication type:

Article

Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation.

Published in:

Arthritis Research & Therapy, 2014, v. 16, n. 2, p. 84, doi. 10.1186/ar4526

By:

Woetzel, Dirk;
Huber, Rene;
Kupfer, Peter;
Pohlers, Dirk;
Pfaff, Michael;
Driesch, Dominik;
Häupl, Thomas;
Koczan, Dirk;
Stiehl, Peter;
Guthke, Reinhard;
Kinne, Raimund W.

Publication type:

Article