Works by Guru, Santosh

Results: 36

Anticancer activity of RM-3-22: a TAZQ-based hydroxamic acid derivative targeting NSCLC in vitro and in vivo.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1544666

By:

Chatterjee, Essha;
Sharma, Ram;
Dey, Biswajit;
Singh, Hoshiyar;
Naik, Aliva;
Khan, Anjesh;
Basak, Santanu;
Bansode, Ankush;
Sachdeva, Ritika;
Sharma, Anamika;
Kumar, Rahul;
Naik, Pradeep;
Singh, Pankaj Kumar;
Nepali, Kunal;
Guru, Santosh Kumar

Publication type:

Article

Induction of apoptosis in human bladder cancer cells by triterpenoids isolated from Holarrhena antidysenterica through differential reactive oxygen species generation.

Published in:

Natural Product Research, 2021, v. 35, n. 24, p. 5629, doi. 10.1080/14786419.2020.1819272

By:

Ghosh, Anindita;
Roy, Rituparna;
Chatterjee, Essha;
Bankura, Biswabandhu;
Guru, Santosh;
Panda, Chinmay Kumar

Publication type:

Article

Terpenoid and flavonoid spectrum of in vitro cultures of Glycyrrhiza glabra revealed high chemical heterogeneity: platform to understand biosynthesis.

Published in:

Plant Cell, Tissue & Organ Culture, 2016, v. 124, n. 3, p. 507, doi. 10.1007/s11240-015-0910-4

By:

Khan, Saima;
Pandotra, Pankaj;
Manzoor, Malik;
Kushwaha, Manoj;
Sharma, Rajni;
Jain, Shreyansh;
Ahuja, Ashok;
Amancha, Vishal;
Bhushan, Sashi;
Guru, Santosh;
Gupta, Ajai;
Vishwakarma, Ram;
Gupta, Suphla

Publication type:

Article

Understanding the Radiobiology of Central Nervous System Diseases in the Golden Age of Radiosurgery—Does It Matter?

Published in:

Brain Sciences (2076-3425), 2025, v. 15, n. 6, p. 649, doi. 10.3390/brainsci15060649

By:

Lam, Fred C.;
Byun, John;
Guru, Santosh;
AbuReesh, Deyaldeen;
Hori, Yusuke S.;
Rahimy, Elham;
Pollom, Erqi Liu;
Soltys, Scott;
Park, David J.;
Chang, Steven D.

Publication type:

Article

Use of Carbon Fiber Implants to Improve the Safety and Efficacy of Radiation Therapy for Spine Tumor Patients.

Published in:

2025

By:

Lam, Fred C.;
Guru, Santosh;
AbuReesh, Deyaldeen;
Hori, Yusuke S.;
Chuang, Cynthia;
Liu, Lianli;
Wang, Lei;
Gu, Xuejun;
Szalkowski, Gregory A.;
Wang, Ziyi;
Wohlers, Christopher;
Tayag, Armine;
Emrich, Sara C.;
Ustrzynski, Louisa;
Zygourakis, Corinna C.;
Desai, Atman;
Hayden Gephart, Melanie;
Byun, John;
Pollom, Erqi Liu;
Rahimy, Elham

Publication type:

Literature Review

"Beyond the Knife"—Applying Theranostic Technologies to Enhance Outcomes in Neurosurgical Oncology.

Published in:

Brain Sciences (2076-3425), 2024, v. 14, n. 12, p. 1253, doi. 10.3390/brainsci14121253

By:

Guru, Santosh;
Lam, Fred C.;
Akhavan-Sigari, Amirhossein;
Hori, Yusuke S.;
AbuReesh, Deyaaldeen;
Tayag, Armine;
Emrich, Sara C.;
Ustrzynski, Louisa;
Park, David J.;
Chang, Steven D.

Publication type:

Article

Design, Fabrication and Evaluation of Stabilized Polymeric mixed micelles for Effective Management in Cancer Therapy.

Published in:

Pharmaceutical Research, 2022, v. 39, n. 11, p. 2761, doi. 10.1007/s11095-022-03395-8

By:

Chary, Padakanti Sandeep;
Rajana, Naveen;
Devabattula, Geetanjali;
Bhavana, Valamla;
Singh, Hoshiyar;
Godugu, Chandraiah;
Guru, Santosh Kumar;
Singh, Shashi Bala;
Mehra, Neelesh Kumar

Publication type:

Article

Serotype-dependent recombinant adeno-associated vector (AAV) infection of Epstein–Barr virus-positive B-cells, towards recombinant AAV-based therapy of focal EBV + lymphoproliferative disorders.

Published in:

Virology Journal, 2021, v. 18, n. 1, p. 1, doi. 10.1186/s12985-021-01695-w

By:

Ahmadi, Elham;
Ravanshad, Mehrdad;
Xie, Jun;
Panigrahi, Rajesh;
Jubbal, Sandeep S.;
Guru, Santosh Kumar;
Guangping, Gao;
Ziyaeyan, Mazyar;
Fingeroth, Joyce

Publication type:

Article

Unveiling the healing properties of 2,3-dehydrosilychristin: a potential silymarin-derived flavonolignan from Vitex negundo.

Published in:

Natural Product Research, 2025, v. 39, n. 10, p. 2771, doi. 10.1080/14786419.2024.2312542

By:

Tripathi, Nancy;
Naik, Aliva;
Kumar, Dulla Naveen;
Bhardwaj, Nivedita;
Goel, Bharat;
Kumar, Sanjay;
Chakrabarty, Sanheeta;
Ranjan, Amit;
Guru, Santosh Kumar;
Kumar, Sanjeev;
Agrawal, Ashish;
Jain, Shreyans K.

Publication type:

Article

Mahamanalactone A, a new triterpenoid from Dysoxylum malabaricum bark: a case study for rapid identification of new metabolites via LC-HRMS profiling and database mining strategy.

Published in:

2025

By:

Bhardwaj, Nivedita;
S., Swathilakshmi;
Tripathi, Nancy;
Kumar, Sanjay;
Lal, Uma Ranjan;
G., Ravikanth;
Guru, Santosh Kumar;
Jain, Shreyans K.

Publication type:

Case Study

Isolation of a new cytotoxic colchinoid from Gloriosa superba roots.

Published in:

Natural Product Research, 2023, v. 37, n. 23, p. 3909, doi. 10.1080/14786419.2022.2158464

By:

Goel, Bharat;
Reddy, Harichander;
Cholkar, Anjali;
Kumar, Sanjeev;
Guru, Santosh Kumar;
Jain, Shreyans K.

Publication type:

Article

LCMS-DNP based dereplication of Araucaria cunninghamii Mudie gum-resin: identification of new cytotoxic labdane diterpene.

Published in:

Natural Product Research, 2022, v. 36, n. 24, p. 6207, doi. 10.1080/14786419.2021.2024530

By:

Sahu, Bharat;
Bhardwaj, Nivedita;
Chatterjee, Essha;
Dey, Biswajit;
Tripathi, Nancy;
Goel, Bharat;
Kushwaha, Manoj;
Kumar, Brijesh;
Singh, Bikarma;
Guru, Santosh Kumar;
Jain, Shreyans K.

Publication type:

Article

Synthesis, in vitro Cytotoxicity Evaluation, and Docking Studies of Gloriosine Derivatives as Potential Anticancer Agents.

Published in:

ChemistrySelect, 2023, v. 8, n. 32, p. 1, doi. 10.1002/slct.202301063

By:

Goel, Bharat;
Naik, Aliva;
Tripathi, Nancy;
Khan, Anjesh;
Bansal, Sunil;
Bansal, Shivani;
Kumar Guru, Santosh;
Jain, Shreyans K.

Publication type:

Article

Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2276665

By:

Sharma, Sachin;
Chandra, Kavya;
Naik, Aliva;
Sharma, Anamika;
Sharma, Ram;
Thakur, Amandeep;
Grewal, Ajmer Singh;
Dhingra, Ashwani K.;
Banerjee, Arnab;
Liou, Jing Ping;
Guru, Santosh Kumar;
Nepali, Kunal

Publication type:

Article

The Neoteric Paradigm of Biomolecule-Functionalized Albumin-Based Targeted Cancer Therapeutics.

Published in:

AAPS PharmSciTech, 2024, v. 25, n. 8, p. 1, doi. 10.1208/s12249-024-02977-6

By:

Gunjkar, Swati;
Gupta, Ujala;
Nair, Rahul;
Paul, Priti;
Aalhate, Mayur;
Mahajan, Srushti;
Maji, Indrani;
Chourasia, Manish K.;
Guru, Santosh Kumar;
Singh, Pankaj Kumar

Publication type:

Article

Chitosan-Stearic Acid Based Polymeric Micelles for the Effective Delivery of Tamoxifen: Cytotoxic and Pharmacokinetic Evaluation.

Published in:

AAPS PharmSciTech, 2017, v. 18, n. 3, p. 759, doi. 10.1208/s12249-016-0563-6

By:

Thotakura, Nagarani;
Dadarwal, Mukesh;
Kumar, Pramod;
Sharma, Gajanand;
Guru, Santosh;
Bhushan, Shashi;
Raza, Kaisar;
Katare, Om

Publication type:

Article

The reactivity of indole-[3,4-b]-azepin-1,5-dione for halogenations and synthesis of alkylamine substituted indole-[3,4-b]-azepine derivatives.

Published in:

Synthetic Communications, 2025, v. 55, n. 2, p. 166, doi. 10.1080/00397911.2024.2438716

By:

Negi, Aakansha;
Gupta, Anup A.;
Kikon, Chichanbemo E.;
S., Swathilakshmi;
Guru, Santosh Kumar;
Kaki, Venkata Rao

Publication type:

Article

The anti-angiogenic and cytotoxic effects of the boswellic acid analog BA145 are potentiated by autophagy inhibitors.

Published in:

Molecular Cancer, 2015, v. 14, n. 1, p. 1, doi. 10.1186/1476-4598-14-6

By:

Pathania, Anup S.;
Wani, Zahoor A.;
Guru, Santosh K.;
Kumar, Suresh;
Bhushan, Shashi;
Korkaya, Hasan;
Seals, Darren F.;
Kumar, Ajay;
Mondhe, Dilip M.;
Ahmed, Zabeer;
Chandan, Bal K.;
Malik, Fayaz

Publication type:

Article

The anti-angiogenic and cytotoxic effects of the boswellic acid analog BA145 are potentiated by autophagy inhibitors.

Published in:

Molecular Cancer, 2015, v. 14, n. 1, p. 115, doi. 10.1186/1476-4598-14-6

By:

Pathania, Anup S.;
Wani, Zahoor A.;
Guru, Santosh K.;
Kumar, Suresh;
Bhushan, Shashi;
Korkaya, Hasan;
Seals, Darren F.;
Kumar, Ajay;
Mondhe, Dilip M.;
Ahmed, Zabeer;
Chandan, Bal K.;
Malik, Fayaz

Publication type:

Article

Fascaplysin Induces Caspase Mediated Crosstalk Between Apoptosis and Autophagy Through the Inhibition of PI3K/AKT/mTOR Signaling Cascade in Human Leukemia HL-60 Cells.

Published in:

Journal of Cellular Biochemistry, 2015, v. 116, n. 6, p. 985, doi. 10.1002/jcb.25053

By:

Kumar, Suresh;
Guru, Santosh Kumar;
Pathania, Anup Singh;
Manda, Sudhakar;
Kumar, Ajay;
Bharate, Sandip B.;
Vishwakarma, Ram A.;
Malik, Fayaz;
Bhushan, Shashi

Publication type:

Article

Two new amides with cytotoxic activity from the fruits of Piper longum.

Published in:

Journal of Asian Natural Products Research, 2011, v. 13, n. 2, p. 143, doi. 10.1080/10286020.2010.546789

By:

Mishra, Priyanka;
Sinha, Sadhna;
Guru, Santosh Kumar;
Bhushan, Shashi;
Vishwakarma, R.A.;
Ghosal, Sabari

Publication type:

Article

Reversal of boswellic acid analog BA145 induced caspase dependent apoptosis by PI3K inhibitor LY294002 and MEK inhibitor PD98059.

Published in:

Apoptosis, 2013, v. 18, n. 12, p. 1561, doi. 10.1007/s10495-013-0889-4

By:

Pathania, Anup S.;
Joshi, Amit;
Kumar, Suresh;
Guru, Santosh K.;
Bhushan, Shashi;
Sharma, Parduman R.;
Bhat, Wajid W.;
Saxena, Ajit K.;
Singh, Jaswant;
Shah, Bhahwal A.;
Andotra, Samar S.;
Taneja, Subhash C.;
Malik, Fayaz A.;
Kumar, Ajay

Publication type:

Article

Tiron and trolox potentiate the autophagic cell death induced by magnolol analog Ery5 by activation of Bax in HL-60 cells.

Published in:

Apoptosis, 2013, v. 18, n. 5, p. 605, doi. 10.1007/s10495-013-0805-y

By:

Kumar, Suresh;
Kumar, Ajay;
Pathania, Anup;
Guru, Santosh;
Jada, Srinivas;
Sharma, Parduman;
Bhushan, Shashi;
Saxena, Ajit;
Kumar, H.;
Malik, Fayaz

Publication type:

Article

Chitosan functionalized PCL nanoparticles bearing tyrosine kinase inhibitor osimertinib mesylate for effective lung cancer therapy.

Published in:

Pharmaceutical Development & Technology, 2023, v. 28, n. 5, p. 460, doi. 10.1080/10837450.2023.2206668

By:

Dhuri, Anish;
Sriram, Anitha;
Aalhate, Mayur;
Mahajan, Srushti;
Parida, Kishan Kumar;
Singh, Hoshiyar;
Gupta, Ujala;
Maji, Indrani;
Guru, Santosh Kumar;
Singh, Pankaj Kumar

Publication type:

Article

Antiproliferative activity and induction of apoptosis by Annona muricata (Annonaceae) extract on human cancer cells.

Published in:

BMC Complementary & Alternative Medicine, 2014, v. 14, n. 1, p. 1070, doi. 10.1186/1472-6882-14-516

By:

Pieme, Constant Anatole;
Kumar, Santosh Guru;
Dongmo, Mireille Sylviane;
Moukette, Bruno Moukette;
Boyoum, Fabrice Fekam;
Ngogang, Jeanne Yonkeu;
Saxena, Ajit Kumar

Publication type:

Article

Induction of mitochondrial dependent apoptosis and cell cycle arrest in human promyelocytic leukemia HL-60 cells by an extract from Dorstenia psilurus: a spice from Cameroon.

Published in:

BMC Complementary & Alternative Medicine, 2013, v. 13, n. 1, p. 223, doi. 10.1186/1472-6882-13-223

By:

Pieme, Constant Anatole;
Guru, Santosh Kumar;
Ambassa, Pantaleon;
Kumar, Suresh;
Ngameni, Bathelemy;
Ngogang, Jeanne Yonkeu;
Bhushan, Shashi;
Saxena, Ajit Kumar

Publication type:

Article

Cytotoxic and antimicrobial activity of selected Cameroonian edible plants.

Published in:

BMC Complementary & Alternative Medicine, 2013, v. 13, n. 1, p. 78, doi. 10.1186/1472-6882-13-78

By:

Dzoyem, Jean Paul;
Guru, Santosh Kumar;
Pieme, Constant Anatole;
Kuete, Victor;
Sharma, Akash;
Ali Khan, Inshad;
Saxena, Ajit Kumar;
Vishwakarma, Ram Anuj

Publication type:

Article

Emerging In Vitro and In Vivo Models: Hope for the Better Understanding of Cancer Progression and Treatment.

Published in:

Advanced Biology, 2024, v. 8, n. 6, p. 1, doi. 10.1002/adbi.202300487

By:

Yadav, Rachana;
Mahajan, Srushti;
Singh, Hoshiyar;
Mehra, Neelesh Kumar;
Madan, Jitender;
Doijad, Nandkumar;
Singh, Pankaj Kumar;
Guru, Santosh Kumar

Publication type:

Article

VEGF-neuropilin-2 signaling promotes stem-like traits in breast cancer cells by TAZ-mediated repression of the Rac GAP β2-chimaerin.

Published in:

Science Signaling, 2018, v. 11, n. 528, p. 1, doi. 10.1126/scisignal.aao6897

By:

Elaimy, Ameer L.;
Guru, Santosh;
Chang, Cheng;
Ou, Jianhong;
Amante, John J.;
Zhu, Lihua Julie;
Goel, Hira Lal;
Mercurio, Arthur M.

Publication type:

Article

The Synthetic Tryptanthrin Analogue Suppresses STAT3 Signaling and Induces Caspase Dependent Apoptosis via ERK Up Regulation in Human Leukemia HL-60 Cells.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0110411

By:

Pathania, Anup S.;
Kumar, Suresh;
Guru, Santosh K.;
Bhushan, Shashi;
Sharma, Parduman R.;
Aithagani, Sravan K.;
Singh, Parvinder P.;
Vishwakarma, Ram A.;
Kumar, Ajay;
Malik, Fayaz

Publication type:

Article

Ionic Liquid Assisted Green Synthesis of Quinoxaline Based Bisspirooxindoles: Anticancer Evaluation and Molecular Dynamics.

Published in:

ChemistrySelect, 2024, v. 9, n. 42, p. 1, doi. 10.1002/slct.202403608

By:

Kanchrana, Madhu;
Krishna, Gamidi Rama;
Dey, Biswajit;
Pandey, Nandita;
Guru, Santosh Kumar;
Sangolkar, Akanksha Ashok;
Pawar, Ravinder;
Basavoju, Srinivas

Publication type:

Article

Antiproliferative and antimicrobial activities of alkylbenzoquinone derivatives from Ardisia kivuensis.

Published in:

Pharmaceutical Biology, 2014, v. 52, n. 3, p. 392, doi. 10.3109/13880209.2013.837076

By:

Paul, Dzoyem J.;
Laure, Ndontsa B.;
Guru, Santosh K.;
Khan, Inshad A.;
Ajit, Saxena K.;
Vishwakarma, Ram A.;
Pierre, Tane

Publication type:

Article

Acalabrutinib as a novel hope for the treatment of breast and lung cancer: an in-silico proof of concept.

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 3, p. 1469, doi. 10.1080/07391102.2023.2217923

By:

Khaparkhuntikar, Kedar;
Maji, Indrani;
Gupta, Sunil Kumar;
Mahajan, Srushti;
Aalhate, Mayur;
Sriram, Anitha;
Gupta, Ujala;
Guru, Santosh Kumar;
Kulkarni, Prachi;
Singh, Pankaj Kumar

Publication type:

Article

Chemometric-Based Analysis of Metabolomics Studies of Bioactive Fractions of Pleurotus osteratus and Their Correlation with In Vitro Anti-Cancer Activity.

Published in:

Applied Biochemistry & Biotechnology, 2023, v. 195, n. 7, p. 4602, doi. 10.1007/s12010-023-04325-z

By:

Shreya, Singh;
Kasote, Deepak;
Mohapatra, Debadatta;
Naik, Gaurav Gopal;
Guru, Santosh Kumar;
Sreenivasulu, Nese;
Sharma, Yashpal;
Sahu, Alakh N.

Publication type:

Article

Tracing the Anti-cancer Mechanism of Pleurotus osteratus by the Integrative Approach of Network Pharmacology and Experimental Studies.

Published in:

Applied Biochemistry & Biotechnology, 2023, v. 195, n. 1, p. 152, doi. 10.1007/s12010-022-04111-3

By:

Shreya, Singh;
Kumar, Dulla Naveen;
Mohapatra, Debadatta;
Jaiswal, Shivani;
Naik, Gaurav Gopal;
Guru, Santosh Kumar;
Agarwal, Ashish Kumar;
Ayyannan, Senthil Raja;
Sahu, Alakh N.

Publication type:

Article

Interplay between cell cycle and autophagy induced by boswellic acid analog.

Published in:

Scientific Reports, 2016, p. 33146, doi. 10.1038/srep33146

By:

Pathania, Anup S.;
Guru, Santosh K.;
Kumar, Suresh;
Kumar, Ashok;
Ahmad, Masroor;
Bhushan, Shashi;
Sharma, Parduman R.;
Mahajan, Priya;
Shah, Bhahwal A.;
Sharma, Simmi;
Nargotra, Amit;
Vishwakarma, Ram;
Korkaya, Hasan;
Malik, Fayaz

Publication type:

Article