Works by Gurke, Robert

Results: 37

Machine learning identifies right index finger tenderness as key signal of DAS28-CRP based psoriatic arthritis activity.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-49574-4

By:

Rischke, Samuel;
Poor, Sorwe Mojtahed;
Gurke, Robert;
Hahnefeld, Lisa;
Köhm, Michaela;
Ultsch, Alfred;
Geisslinger, Gerd;
Behrens, Frank;
Lötsch, Jörn

Publication type:

Article

TAM receptors mediate the Fpr2-driven pain resolution and fibrinolysis after nerve injury.

Published in:

Acta Neuropathologica, 2024, v. 149, n. 1, p. 1, doi. 10.1007/s00401-024-02840-9

By:

Hartmannsberger, Beate;
Ben-Kraiem, Adel;
Kramer, Sofia;
Guidolin, Carolina;
Kazerani, Ida;
Doppler, Kathrin;
Thomas, Dominique;
Gurke, Robert;
Sisignano, Marco;
Kalelkar, Pranav P.;
García, Andrés J.;
Monje, Paula V.;
Sammeth, Michael;
Nusrat, Asma;
Brack, Alexander;
Krug, Susanne M.;
Sommer, Claudia;
Rittner, Heike L.

Publication type:

Article

Omics and Multi-Omics Analysis for the Early Identification and Improved Outcome of Patients with Psoriatic Arthritis.

Published in:

Biomedicines, 2022, v. 10, n. 10, p. N.PAG, doi. 10.3390/biomedicines10102387

By:

Gurke, Robert;
Bendes, Annika;
Bowes, John;
Koehm, Michaela;
Twyman, Richard M.;
Barton, Anne;
Elewaut, Dirk;
Goodyear, Carl;
Hahnefeld, Lisa;
Hillenbrand, Rainer;
Hunter, Ewan;
Ibberson, Mark;
Ioannidis, Vassilios;
Kugler, Sabine;
Lories, Rik J.;
Resch, Eduard;
Rüping, Stefan;
Scholich, Klaus;
Schwenk, Jochen M.;
Waddington, James C.

Publication type:

Article

Phosphatidylethanolamine Deficiency and Triglyceride Overload in Perilesional Cortex Contribute to Non-Goal-Directed Hyperactivity after Traumatic Brain Injury in Mice.

Published in:

Biomedicines, 2022, v. 10, n. 4, p. 914, doi. 10.3390/biomedicines10040914

By:

Hahnefeld, Lisa;
Vogel, Alexandra;
Gurke, Robert;
Geisslinger, Gerd;
Schäfer, Michael K. E.;
Tegeder, Irmgard

Publication type:

Article

Sphingolipid and Endocannabinoid Profiles in Adult Attention Deficit Hyperactivity Disorder.

Published in:

Biomedicines, 2021, v. 9, n. 9, p. 1173, doi. 10.3390/biomedicines9091173

By:

Brunkhorst-Kanaan, Nathalie;
Trautmann, Sandra;
Schreiber, Yannick;
Thomas, Dominique;
Kittel-Schneider, Sarah;
Gurke, Robert;
Geisslinger, Gerd;
Reif, Andreas;
Tegeder, Irmgard

Publication type:

Article

Low brain endocannabinoids associated with persistent non-goal directed nighttime hyperactivity after traumatic brain injury in mice.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71879-x

By:

Vogel, Alexandra;
Wilken-Schmitz, Annett;
Hummel, Regina;
Lang, Manuel;
Gurke, Robert;
Schreiber, Yannick;
Schäfer, Michael K. E.;
Tegeder, Irmgard

Publication type:

Article

UGCG overexpression leads to increased glycolysis and increased oxidative phosphorylation of breast cancer cells.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65182-y

By:

Schömel, Nina;
Gruber, Lisa;
Alexopoulos, Stephanie J.;
Trautmann, Sandra;
Olzomer, Ellen M.;
Byrne, Frances L.;
Hoehn, Kyle L.;
Gurke, Robert;
Thomas, Dominique;
Ferreirós, Nerea;
Geisslinger, Gerd;
Wegner, Marthe-Susanna

Publication type:

Article

Metabolic Profiling in Rheumatoid Arthritis, Psoriatic Arthritis, and Psoriasis: Elucidating Pathogenesis, Improving Diagnosis, and Monitoring Disease Activity.

Published in:

Journal of Personalized Medicine, 2022, v. 12, n. 6, p. 924, doi. 10.3390/jpm12060924

By:

Dorochow, Erika;
Köhm, Michaela;
Hahnefeld, Lisa;
Gurke, Robert

Publication type:

Article

High Glucosylceramides and Low Anandamide Contribute to Sensory Loss and Pain in Parkinson's Disease.

Published in:

Movement Disorders, 2020, v. 35, n. 10, p. 1822, doi. 10.1002/mds.28186

By:

Klatt‐Schreiner, Katharina;
Valek, Lucie;
Kang, Jun‐Suk;
Khlebtovsky, Alexander;
Trautmann, Sandra;
Hahnefeld, Lisa;
Schreiber, Yannick;
Gurke, Robert;
Thomas, Dominique;
Wilken‐Schmitz, Annett;
Wicker, Sabine;
Auburger, Georg;
Geisslinger, Gerd;
Lötsch, Jörn;
Pfeilschifter, Waltraud;
Djaldetti, Ruth;
Tegeder, Irmgard

Publication type:

Article

Increased Fat Taste Preference in Progranulin-Deficient Mice.

Published in:

Nutrients, 2021, v. 13, n. 11, p. 4125, doi. 10.3390/nu13114125

By:

Schumann, Lana;
Wilken-Schmitz, Annett;
Trautmann, Sandra;
Vogel, Alexandra;
Schreiber, Yannick;
Hahnefeld, Lisa;
Gurke, Robert;
Geisslinger, Gerd;
Tegeder, Irmgard

Publication type:

Article

Impact of Hyperhomocysteinemia and Different Dietary Interventions on Cognitive Performance in a Knock-in Mouse Model for Alzheimer's Disease.

Published in:

Nutrients, 2020, v. 12, n. 11, p. 3248, doi. 10.3390/nu12113248

By:

Nieraad, Hendrik;
de Bruin, Natasja;
Arne, Olga;
Hofmann, Martine C. J.;
Schmidt, Mike;
Saito, Takashi;
Saido, Takaomi C.;
Gurke, Robert;
Schmidt, Dominik;
Till, Uwe;
Parnham, Michael J.;
Geisslinger, Gerd

Publication type:

Article

Brain region specific regulation of anandamide (down) and sphingosine-1-phosphate (up) in association with anxiety (AEA) and resilience (S1P) in a mouse model of chronic unpredictable mild stress.

Published in:

Pflügers Archiv: European Journal of Physiology, 2024, v. 476, n. 12, p. 1863, doi. 10.1007/s00424-024-03012-0

By:

Fischer, Caroline;
Thomas, Dominique;
Gurke, Robert;
Tegeder, Irmgard

Publication type:

Article

Increased glucosylceramide production leads to decreased cell energy metabolism and lowered tumor marker expression in non-cancerous liver cells.

Published in:

Cellular & Molecular Life Sciences, 2021, v. 78, n. 21/22, p. 7025, doi. 10.1007/s00018-021-03958-9

By:

Wegner, Marthe-Susanna;
Schömel, Nina;
Olzomer, Ellen M.;
Trautmann, Sandra;
Olesch, Catherine;
Byrne, Frances L.;
Brüne, Bernhard;
Gurke, Robert;
Ferreirós, Nerea;
Weigert, Andreas;
Geisslinger, Gerd;
Hoehn, Kyle L.

Publication type:

Article

Endothelial Sphingosine-1-Phosphate Receptor 4 Regulates Blood-Brain Barrier Permeability and Promotes a Homeostatic Endothelial Phenotype.

Published in:

Journal of Neuroscience, 2022, v. 42, n. 10, p. 1908, doi. 10.1523/JNEUROSCI.0188-21.2021

By:

Hansen, Lena;
Lohfink, Niklas;
Vutukuri, Rajkumar;
Kestner, Roxane-Isabelle;
Trautmann, Sandra;
Hecht, Max;
Wagner, Pia Viktoria;
Spitzer, Daniel;
Khel, Maryam Ibrahim;
Macas, Jadranka;
Ferreirós, Nerea;
Gurke, Robert;
Günther, Stefan;
Pfeilschifter, Waltraud;
Devraj, Kavi

Publication type:

Article

A helminth enzyme subverts macrophage-mediated immunity by epigenetic targeting of prostaglandin synthesis.

Published in:

Science Immunology, 2024, v. 9, n. 102, p. 1, doi. 10.1126/sciimmunol.adl1467

By:

Bohnacker, Sina;
Henkel, Fiona D. R.;
Hartung, Franziska;
Geerlof, Arie;
Riemer, Sandra;
Prodjinotho, Ulrich F.;
Salah, Eya Ben;
Mourão, André Santos Dias;
Bohn, Stefan;
Teder, Tarvi;
Thomas, Dominique;
Gurke, Robert;
Boeckel, Christiane;
Ud-Dean, Minhaz;
König, Ann-Christine;
Quaranta, Alessandro;
Alessandrini, Francesca;
Lechner, Antonie;
Spitzlberger, Benedikt;
Kabat, Agnieszka M.

Publication type:

Article

Visually guided preprocessing of bioanalytical laboratory data using an interactive R notebook (pguIMP).

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 11, p. 1371, doi. 10.1002/psp4.12704

By:

Malkusch, Sebastian;
Hahnefeld, Lisa;
Gurke, Robert;
Lötsch, Jörn

Publication type:

Article

A Data Science-Based Analysis Points at Distinct Patterns of Lipid Mediator Plasma Concentrations in Patients With Dementia.

Published in:

Frontiers in Psychiatry, 2019, p. N.PAG, doi. 10.3389/fpsyt.2019.00041

By:

Gurke, Robert;
Etyemez, Semra;
Prvulovic, David;
Thomas, Dominique;
Fleck, Stefanie C.;
Reif, Andreas;
Geisslinger, Gerd;
Lötsch, Jörn

Publication type:

Article

Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inflammatory reactions.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1148806

By:

Neb, Holger;
Roth, Verena;
Roos, Jessica;
Bauer, Tom;
Urbschat, Anja;
Heinicke, Ulrike;
Angioni, Carlo;
Steinhilber, Dieter;
Piesche, Matthias;
Ferreirós, Nerea;
Gurke, Robert;
Geisslinger, Gerd;
Utech, Edith;
Zacharowski, Kai;
Meybohm, Patrick;
Paulus, Patrick;
Schmitt, Elke;
Maier, Thorsten Jürgen

Publication type:

Article

Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inflammatory reactions.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1148806

By:

Neb, Holger;
Roth, Verena;
Roos, Jessica;
Bauer, Tom;
Urbschat, Anja;
Heinicke, Ulrike;
Angioni, Carlo;
Steinhilber, Dieter;
Piesche, Matthias;
Ferreirós, Nerea;
Gurke, Robert;
Geisslinger, Gerd;
Utech, Edith;
Zacharowski, Kai;
Meybohm, Patrick;
Paulus, Patrick;
Schmitt, Elke;
Maier, Thorsten Jürgen

Publication type:

Article

The Roles of Long-Term Hyperhomocysteinemia and Micronutrient Supplementation in the App<sup>NL–G–F</sup> Model of Alzheimer's Disease.

Published in:

Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.876826

By:

Nieraad, Hendrik;
de Bruin, Natasja;
Arne, Olga;
Hofmann, Martine C. J.;
Pannwitz, Nina;
Resch, Eduard;
Luckhardt, Sonja;
Schneider, Ann-Kathrin;
Trautmann, Sandra;
Schreiber, Yannick;
Gurke, Robert;
Parnham, Michael J.;
Till, Uwe;
Geisslinger, Gerd

Publication type:

Article

Knock-Out of IKKepsilon Ameliorates Atherosclerosis and Fatty Liver Disease by Alterations of Lipid Metabolism in the PCSK9 Model in Mice.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 19, p. 10721, doi. 10.3390/ijms251910721

By:

Weiss, Ulrike;
Mungo, Eleonora;
Haß, Michelle;
Benning, Denis;
Gurke, Robert;
Hahnefeld, Lisa;
Dorochow, Erika;
Schlaudraff, Jessica;
Schmid, Tobias;
Kuntschar, Silvia;
Meyer, Sofie;
Medert, Rebekka;
Freichel, Marc;
Geisslinger, Gerd;
Niederberger, Ellen

Publication type:

Article

Differential Lipidomics, Metabolomics and Immunological Analysis of Alcoholic and Non-Alcoholic Steatohepatitis in Mice.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 12, p. 10351, doi. 10.3390/ijms241210351

By:

Dorochow, Erika;
Kraus, Nico;
Chenaux-Repond, Nicolas;
Pierre, Sandra;
Kolbinger, Anja;
Geisslinger, Gerd;
Ortiz, Cristina;
Welsch, Christoph;
Trebicka, Jonel;
Gurke, Robert;
Hahnefeld, Lisa;
Klein, Sabine;
Scholich, Klaus

Publication type:

Article

Non-Reproducibility of Oral Rotenone as a Model for Parkinson's Disease in Mice.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12658, doi. 10.3390/ijms232012658

By:

Niederberger, Ellen;
Wilken-Schmitz, Annett;
Manderscheid, Christine;
Schreiber, Yannick;
Gurke, Robert;
Tegeder, Irmgard

Publication type:

Article

Effects of Alzheimer-Like Pathology on Homocysteine and Homocysteic Acid Levels—An Exploratory In Vivo Kinetic Study.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 2, p. 927, doi. 10.3390/ijms22020927

By:

Nieraad, Hendrik;
de Bruin, Natasja;
Arne, Olga;
Hofmann, Martine C. J.;
Gurke, Robert;
Schmidt, Dominik;
Ritter, Marcel;
Parnham, Michael J.;
Geisslinger, Gerd

Publication type:

Article

Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-38865-4

By:

Grill, Magdalena;
Högenauer, Christoph;
Blesl, Andreas;
Haybaeck, Johannes;
Golob-Schwarzl, Nicole;
Ferreirós, Nerea;
Thomas, Dominique;
Gurke, Robert;
Trötzmüller, Martin;
Köfeler, Harald C.;
Gallé, Birgit;
Schicho, Rudolf

Publication type:

Article

Effects of Different Storage Conditions on Lipid Stability in Mice Tissue Homogenates.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 4, p. 504, doi. 10.3390/metabo13040504

By:

Dorochow, Erika;
Gurke, Robert;
Rischke, Samuel;
Geisslinger, Gerd;
Hahnefeld, Lisa

Publication type:

Article

Repetitive and compulsive behavior after Early-Life-Pain associated with reduced long-chain sphingolipid species.

Published in:

Cell & Bioscience, 2023, v. 13, n. 1, p. 1, doi. 10.1186/s13578-023-01106-3

By:

Vogel, Alexandra;
Ueberbach, Timo;
Wilken-Schmitz, Annett;
Hahnefeld, Lisa;
Franck, Luisa;
Weyer, Marc-Philipp;
Jungenitz, Tassilo;
Schmid, Tobias;
Buchmann, Giulia;
Freudenberg, Florian;
Brandes, Ralf P.;
Gurke, Robert;
Schwarzacher, Stephan W.;
Geisslinger, Gerd;
Mittmann, Thomas;
Tegeder, Irmgard

Publication type:

Article

Inhibition of DYRK1B BY C81 impedes inflammatory processes in leukocytes by reducing STAT3 activity.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05579-y

By:

Ciurus, Sarah;
Elewa, Mohammed A. F.;
Palmer, Megan A.;
Wolf, Anne;
Hector, Mandy;
Fuhrmann, Dominik C.;
Thomas, Dominique;
Gurke, Robert;
Schwalm, Martin P.;
Berger, Lena;
Zech, Thomas J.;
Burgers, Luisa D.;
Marschalek, Rolf;
Geisslinger, Gerd;
Knapp, Stefan;
Langmann, Thomas;
Bracher, Franz;
Weigert, Andreas;
Fürst, Robert

Publication type:

Article

Antibiotikaeintrag in das urbane Abwasser.

Published in:

Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, 2016, v. 59, n. 2, p. 274, doi. 10.1007/s00103-015-2288-1

By:

Timpel, Patrick;
Gurke, Robert;
Marx, Conrad;
Knoth, Holger;
Fauler, Joachim

Publication type:

Article

The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells.

Published in:

Basic Research in Cardiology, 2020, v. 115, n. 3, p. 1, doi. 10.1007/s00395-020-0793-3

By:

Pflüger-Müller, Beatrice;
Oo, James A.;
Heering, Jan;
Warwick, Timothy;
Proschak, Ewgenij;
Günther, Stefan;
Looso, Mario;
Rezende, Flávia;
Fork, Christian;
Geisslinger, Gerd;
Thomas, Dominique;
Gurke, Robert;
Steinhilber, Dieter;
Schulz, Marcel;
Leisegang, Matthias S.;
Brandes, Ralf P.

Publication type:

Article

Valproic Acid Treatment after Traumatic Brain Injury in Mice Alleviates Neuronal Death and Inflammation in Association with Increased Plasma Lysophosphatidylcholines.

Published in:

Cells (2073-4409), 2024, v. 13, n. 9, p. 734, doi. 10.3390/cells13090734

By:

Hummel, Regina;
Dorochow, Erika;
Zander, Sonja;
Ritter, Katharina;
Hahnefeld, Lisa;
Gurke, Robert;
Tegeder, Irmgard;
Schäfer, Michael K. E.

Publication type:

Article

Proteomic, metabolomic and lipidomic profiles in community acquired pneumonia for differentiating viral and bacterial infections.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-85229-2

By:

Rischke, Samuel;
Gurke, Robert;
Zielbauer, Ann-Sophie;
Ziegler, Nicole;
Hahnefeld, Lisa;
Köhm, Michaela;
Kannt, Aimo;
Vehreschild, Maria JGT;
Geisslinger, Gerd;
Rohde, Gernot;
Bellinghausen, Carla;
Behrens, Frank;
Study group, CAPNETZ

Publication type:

Article

The endocannabinoid anandamide mediates anti‐inflammatory effects through activation of NR4A nuclear receptors.

Published in:

British Journal of Pharmacology, 2025, v. 182, n. 5, p. 1164, doi. 10.1111/bph.17366

By:

Teichmann, Tom;
Pflüger‐Müller, Beatrice;
Giménez, Virna Margarita Martín;
Sailer, Fiona;
Dirks, Henrik;
Zehr, Simonida;
Warwick, Timothy;
Brettner, Felix;
Munoz‐Tello, Paola;
Zimmer, Andreas;
Tegeder, Irmgard;
Thomas, Dominique;
Gurke, Robert;
Günther, Stefan;
Heering, Jan;
Proschak, Ewgenij;
Geisslinger, Gerd;
Bibli, Iris‐S.;
Heringdorf, Dagmar Meyer zu;
Manucha, Walter

Publication type:

Article

Meloxicam treatment disrupts the regional structure of innate inflammation sites by targeting the pro‐inflammatory effects of prostanoids.

Published in:

British Journal of Pharmacology, 2024, v. 181, n. 7, p. 1051, doi. 10.1111/bph.16261

By:

Schäufele, Tim J.;
Kolbinger, Anja;
Friedel, Joschua;
Gurke, Robert;
Geisslinger, Gerd;
Weigert, Andreas;
Pierre, Sandra;
Scholich, Klaus

Publication type:

Article

Application of clinical and molecular profiling data to improve patient outcomes in psoriatic arthritis.

Published in:

Therapeutic Advances in Musculoskeletal Disease, 2023, p. 1, doi. 10.1177/1759720X231192315

By:

FitzGerald, Oliver;
Behrens, Frank;
Barton, Anne;
Bertheussen, Heidi;
Boutouyrie-Dumont, Bruno;
Coates, Laura;
Davies, Owen;
de Wit, Maarten;
Fagni, Filippo;
Goodyear, Carl S.;
Gurke, Robert;
Hahnefeld, Lisa;
Huppertz, Christine;
Ioannidis, Vassilios;
Ibberson, Mark;
Katz, Arnon;
Klippstein, Maximilian;
Koehm, Michaela;
Korish, Shimon;
Mackay, Sina

Publication type:

Article

Application of clinical and molecular profiling data to improve patient outcomes in psoriatic arthritis.

Published in:

Therapeutic Advances in Musculoskeletal Disease, 2023, v. 15, p. 1, doi. 10.1177/1759720X231192315

By:

FitzGerald, Oliver;
Behrens, Frank;
Barton, Anne;
Bertheussen, Heidi;
Boutouyrie-Dumont, Bruno;
Coates, Laura;
Davies, Owen;
de Wit, Maarten;
Fagni, Filippo;
Goodyear, Carl S.;
Gurke, Robert;
Hahnefeld, Lisa;
Huppertz, Christine;
Ioannidis, Vassilios;
Ibberson, Mark;
Katz, Arnon;
Klippstein, Maximilian;
Koehm, Michaela;
Korish, Shimon;
Mackay, Sina

Publication type:

Article

Top soil removal reduces water pollution from phosphorus and dissolved organic matter and lowers methane emissions from rewetted peatlands.

Published in:

Journal of Applied Ecology, 2018, v. 55, n. 1, p. 311, doi. 10.1111/1365-2664.12931

By:

Zak, Dominik;
Goldhammer, Tobias;
Cabezas, Alavaro;
Gelbrecht, Jörg;
Gurke, Robert;
Wagner, Carola;
Reuter, Hendrik;
Augustin, Jürgen;
Klimkowska, Agata;
McInnes, Robert

Publication type:

Article