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TRAIL-Based Therapies Efficacy in Pediatric Bone Tumors Models Is Modulated by TRAIL Non-Apoptotic Pathway Activation via RIPK1 Recruitment.
Published in:
Cancers, 2022, v. 14, n. 22, p. 5627, doi. 10.3390/cancers14225627
By:
- Brion, Régis;
- Gantier, Malika;
- Biteau, Kevin;
- Taurelle, Julien;
- Brounais-Le Royer, Bénédicte;
- Verrecchia, Franck;
- Rédini, Françoise;
- Guiho, Romain
Publication type:
Article
Recurrent adamantinomatous craniopharyngiomas show MAPK pathway activation, clonal evolution and rare TP53-loss-mediated malignant progression.
Published in:
Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01838-4
By:
- Apps, John R.;
- Gonzalez-Meljem, Jose Mario;
- Guiho, Romain;
- Pickles, Jessica C.;
- Prince, Eric;
- Schwalbe, Edward;
- Joshi, Nikhil;
- Stone, Thomas J.;
- Ogunbiyi, Olumide;
- Chalker, Jane;
- Bassey, Akang;
- Otto, Georg;
- Davies, Rosalind;
- Hughes, Debbie;
- Brandner, Sebastian;
- Tan, Enrica;
- Lee, Victoria;
- Hayhurst, Caroline;
- Kline, Cassie;
- Castellano, Sergi
Publication type:
Article
Cell senescence in neuropathology: A focus on neurodegeneration and tumours.
Published in:
Neuropathology & Applied Neurobiology, 2021, v. 47, n. 3, p. 359, doi. 10.1111/nan.12689
By:
- Carreno, Gabriela;
- Guiho, Romain;
- Martinez‐Barbera, Juan Pedro
Publication type:
Article
TRAIL delivered by mesenchymal stromal/stem cells counteracts tumor development in orthotopic Ewing sarcoma models.
Published in:
International Journal of Cancer, 2016, v. 139, n. 12, p. 2802, doi. 10.1002/ijc.30402
By:
- Guiho, Romain;
- Biteau, Kevin;
- Grisendi, Giulia;
- Taurelle, Julien;
- Chatelais, Mathias;
- Gantier, Malika;
- Heymann, Dominique;
- Dominici, Massimo;
- Redini, Françoise
Publication type:
Article
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.
Published in:
Acta Neuropathologica, 2018, v. 135, n. 5, p. 757, doi. 10.1007/s00401-018-1830-2
By:
- Apps, John R.;
- Carreno, Gabriela;
- Gonzalez-Meljem, Jose Mario;
- Haston, Scott;
- Guiho, Romain;
- Cooper, Julie E.;
- Manshaei, Saba;
- Jani, Nital;
- Hölsken, Annett;
- Pettorini, Benedetta;
- Beynon, Robert J.;
- Simpson, Deborah M.;
- Fraser, Helen C.;
- Hong, Ying;
- Hallang, Shirleen;
- Stone, Thomas J.;
- Virasami, Alex;
- Donson, Andrew M.;
- Jones, David;
- Aquilina, Kristian
Publication type:
Article
Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines.
Published in:
Journal of Neuro-Oncology, 2024, v. 168, n. 2, p. 317, doi. 10.1007/s11060-024-04672-9
By:
- Kocher, Daniela;
- Cao, Lei;
- Guiho, Romain;
- Langhammer, Melanie;
- Lai, Yun-Lu;
- Becker, Pauline;
- Hamdi, Hiba;
- Friedel, Dennis;
- Selt, Florian;
- Vonhören, David;
- Zaman, Julia;
- Valinciute, Gintvile;
- Herter, Sonja;
- Picard, Daniel;
- Rettenmeier, Johanna;
- Maass, Kendra K.;
- Pajtler, Kristian W.;
- Remke, Marc;
- von Deimling, Andreas;
- Pusch, Stefan
Publication type:
Article
Zoledronic acid enhances tumor growth and metastatic spread in a mouse model of jaw osteosarcoma.
Published in:
Oral Diseases, 2024, v. 30, n. 7, p. 4209, doi. 10.1111/odi.14897
By:
- Nham, Than‐Thuy;
- Guiho, Romain;
- Brion, Régis;
- Amiaud, Jérôme;
- Le Royer, Bénédicte Brounais;
- Gomez‐Brouchet, Anne;
- Rédini, Françoise;
- Bertin, Hélios
Publication type:
Article
BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma.
Published in:
Neuro-Oncology, 2023, v. 25, n. 4, p. 735, doi. 10.1093/neuonc/noac199
By:
- Selt, Florian;
- Sigaud, Romain;
- Valinciute, Gintvile;
- Sievers, Philipp;
- Zaman, Julia;
- Alcon, Clara;
- Schmid, Simone;
- Peterziel, Heike;
- Tsai, Jessica W;
- Guiho, Romain;
- Martínez-Barbera, Juan Pedro;
- Pusch, Stefan;
- Deng, Jing;
- Zhai, Yifan;
- Tilburg, Cornelis M van;
- Schuhman, Martin U;
- Damaty, Ahmed El;
- Bandopadhayay, Pratiti;
- Herold-Mende, Christel;
- Deimling, Andreas von
Publication type:
Article
Galactose‐modified duocarmycin prodrugs as senolytics.
Published in:
Aging Cell, 2020, v. 19, n. 4, p. 1, doi. 10.1111/acel.13133
By:
- Guerrero, Ana;
- Guiho, Romain;
- Herranz, Nicolás;
- Uren, Anthony;
- Withers, Dominic J.;
- Martínez‐Barbera, Juan Pedro;
- Tietze, Lutz F.;
- Gil, Jesús
Publication type:
Article

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