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Vemurafenib induces senescence in acute myeloid leukemia and myelodysplastic syndrome by activating the HIPPO signaling pathway: implications for potential targeted therapy.
- Published in:
- Biology Direct, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13062-023-00451-0
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- Article
BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10658, doi. 10.3390/ijms221910658
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- Article
Rétrotransposons et cellules somatiques Parasites ou acteurs actifs du contrôle épigénétique ?
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- Médecine Sciences, 2014, v. 30, n. 6/7, p. 659, doi. 10.1051/medsci/20143006016
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- Article
Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network.
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- Nature Genetics, 2015, v. 47, n. 11, p. 1334, doi. 10.1038/ng.3420
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- Article
Regulation of Hoxb2 by APL-associated PLZF protein.
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- Oncogene, 2003, v. 22, n. 24, p. 3685, doi. 10.1038/sj.onc.1206328
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- Article
Translocations of the RARα gene in acute promyelocytic leukemia.
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- Oncogene, 2001, v. 20, n. 49, p. 7186, doi. 10.1038/sj.onc.1204766
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- Article
Protein Arginine Methyltransferases as Therapeutic Targets in Hematological Malignancies.
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- Cancers, 2022, v. 14, n. 21, p. 5443, doi. 10.3390/cancers14215443
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- Article
The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells.
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- EMBO Journal, 2013, v. 32, n. 13, p. 1941, doi. 10.1038/emboj.2013.118
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- Article
Colocalization and heteromerization between the two human oncogene POZ/zinc finger proteins, LAZ3 (BCL6) and PLZF.
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- Oncogene, 2000, v. 19, n. 54, p. 6240, doi. 10.1038/sj.onc.1203976
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- Article
Post transcriptional control of the epigenetic stem cell regulator PLZF by sirtuin and HDAC deacetylases.
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- Epigenetics & Chromatin, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13072-015-0030-8
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- Article
HDAC4 as a potential therapeutic target in neurodegenerative diseases: a summary of recent achievements.
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- Frontiers in Cellular Neuroscience, 2015, v. 8/9, p. 1, doi. 10.3389/fncel.2015.00042
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- Article
Protein arginine methyltransferase 2 controls inflammatory signaling in acute myeloid leukemia.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06453-6
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- Article
Repeat Element Activation-Driven Inflammation: Role of NFκB and Implications in Normal Development and Cancer?
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- Biomedicines, 2022, v. 10, n. 12, p. 3101, doi. 10.3390/biomedicines10123101
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- Article
A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2).
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- Scientific Reports, 2015, p. 10750, doi. 10.1038/srep10750
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- Article
GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways.
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- Journal of Hematology & Oncology, 2016, v. 9, p. 1, doi. 10.1186/s13045-016-0235-8
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- Article