Works by Guedj, Jeremie

Results: 61

Ebola Virus Infection: Review of the Pharmacokinetic and Pharmacodynamic Properties of Drugs Considered for Testing in Human Efficacy Trials.

Published in:

2016

By:

Madelain, Vincent;
Nguyen, Thi;
Olivo, Anaelle;
Lamballerie, Xavier;
Guedj, Jérémie;
Taburet, Anne-Marie;
Mentré, France;
Nguyen, Thi Huyen Tram;
de Lamballerie, Xavier;
Guedj, Jérémie;
Mentré, France

Publication type:

journal article

Can we use viral kinetic models to individualize treatment?

Published in:

Liver International, 2015, v. 35, n. 2, p. 297, doi. 10.1111/liv.12736

By:

Guedj, Jeremie;
Nguyen, Thi Huyen Tram

Publication type:

Article

Neutralizing Antibody Levels as a Correlate of Protection Against SARS‐CoV‐2 Infection: A Modeling Analysis.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 1, p. 86, doi. 10.1002/cpt.3069

By:

Lingas, Guillaume;
Planas, Delphine;
Péré, Hélène;
Porrot, Françoise;
Guivel‐Benhassine, Florence;
Staropoli, Isabelle;
Duffy, Darragh;
Chapuis, Nicolas;
Gobeaux, Camille;
Veyer, David;
Delaugerre, Constance;
Le Goff, Jérôme;
Getten, Prunelle;
Hadjadj, Jérôme;
Bellino, Adèle;
Parfait, Béatrice;
Treluyer, Jean‐Marc;
Schwartz, Olivier;
Guedj, Jérémie;
Kernéis, Solen

Publication type:

Article

A Semi‐mechanistic Model to Characterize the Long‐Term Dynamics of Hepatitis B Virus Markers During Treatment With Lamivudine and Pegylated Interferon.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 2, p. 390, doi. 10.1002/cpt.2798

By:

El Messaoudi, Selma;
Lemenuel‐Diot, Annabelle;
Gonçalves, Antonio;
Guedj, Jérémie

Publication type:

Article

Modeling the Effect of DAV132, a Novel Colon‐Targeted Adsorbent, on Fecal Concentrations of Moxifloxacin and Gut Microbiota Diversity in Healthy Volunteers.

Published in:

Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1045, doi. 10.1002/cpt.1977

By:

Guk, Jinju;
Guedj, Jérémie;
Burdet, Charles;
Andremont, Antoine;
Gunzburg, Jean;
Ducher, Annie;
Mentré, France

Publication type:

Article

Dose Rationale for Favipiravir Use in Patients Infected With SARS‐CoV‐2.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 2, p. 188, doi. 10.1002/cpt.1877

By:

Eloy, Philippine;
Solas, Caroline;
Touret, Franck;
Mentré, France;
Malvy, Denis;
Lamballerie, Xavier;
Guedj, Jérémie

Publication type:

Article

Association Between Tumor Size Kinetics and Survival in Patients With Urothelial Carcinoma Treated With Atezolizumab: Implication for Patient Follow‐Up.

Published in:

Clinical Pharmacology & Therapeutics, 2019, v. 106, n. 4, p. 810, doi. 10.1002/cpt.1450

By:

Tardivon, Coralie;
Desmée, Solène;
Kerioui, Marion;
Bruno, René;
Wu, Benjamin;
Mentré, France;
Mercier, François;
Guedj, Jérémie

Publication type:

Article

Clinical trial simulation to evaluate power to compare the antiviral effectiveness of two hepatitis C protease inhibitors using nonlinear mixed effect models: a viral kinetic approach.

Published in:

BMC Medical Research Methodology, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2288-13-60

By:

Laouénan, Cédric;
Guedj, Jeremie;
Mentré, France

Publication type:

Article

Clinical trial simulation to evaluate power to compare the antiviral effectiveness of two hepatitis C protease inhibitors using nonlinear mixed effect models: a viral kinetic approach.

Published in:

2013

By:

Laouénan, Cédric;
Guedj, Jeremie;
Mentré, France

Publication type:

journal article

Survival of SARS-CoV-2 on Non-Porous Materials in an Experimental Setting Representative of Fomites.

Published in:

Coatings (2079-6412), 2021, v. 11, n. 4, p. 371, doi. 10.3390/coatings11040371

By:

Bonil, Laura;
Lingas, Guillaume;
Coupeau, Damien;
Lucet, Jean-Christophe;
Guedj, Jérémie;
Visseaux, Benoît;
Muylkens, Benoît

Publication type:

Article

Umbilical artery Doppler assessment: a clear disparity in ultrasound practice in a national survey.

Published in:

Acta Obstetricia et Gynecologica Scandinavica, 2013, v. 92, n. 9, p. 1115, doi. 10.1111/aogs.12167

By:

Cohen, Jonathan;
Guedj, Jeremie;
Fries, Nicolas

Publication type:

Article

Modelling the effectiveness of antiviral treatment strategies to prevent household transmission of acute respiratory viruses.

Published in:

PLoS Computational Biology, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pcbi.1012573

By:

Zaaraoui, Hind;
Schumer, Clarisse;
Duval, Xavier;
Hoen, Bruno;
Opatowski, Lulla;
Guedj, Jérémie

Publication type:

Article

Longitudinal analysis of organ-specific tumor lesion sizes in metastatic colorectal cancer patients receiving first line standard chemotherapy in combination with anti-angiogenic treatment.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2020, v. 47, n. 6, p. 613, doi. 10.1007/s10928-020-09714-z

By:

Mercier, Francois;
Kerioui, Marion;
Desmée, Solène;
Guedj, Jeremie;
Krieter, Oliver;
Bruno, Rene

Publication type:

Article

Quantifying the relationship between SARS-CoV-2 viral load and infectiousness.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.69302

By:

Marc, Aurélien;
Kerioui, Marion;
Blanquart, Franc¸ois;
Bertrand, Julie;
Mitjà, Oriol;
Corbacho-Monné, Marc;
Marks, Michael;
Guedj, Jeremie

Publication type:

Article

Modelling the association between biomarkers and clinical outcome: An introduction to nonlinear joint models.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 4, p. 1452, doi. 10.1111/bcp.15200

By:

Kerioui, Marion;
Bertrand, Julie;
Bruno, René;
Mercier, François;
Guedj, Jérémie;
Desmée, Solène

Publication type:

Article

Modulation of HCV replication after combination antiretroviral therapy in HCV/HIV co-infected patients.

Published in:

Science Translational Medicine, 2014, v. 6, n. 246, p. 1, doi. 10.1126/scitranslmed.3008195

By:

Sherman, Kenneth E.;
Guedj, Jeremie;
Shata, Mohamed Tarek;
Blackard, Jason T.;
Rouster, Susan D.;
Castro, Mario;
Feinberg, Judith;
Sterling, Richard K.;
Goodman, Zachary;
Aronow, Bruce J.;
Perelson, Alan S.

Publication type:

Article

Model Averaging in Viral Dynamic Models.

Published in:

AAPS Journal, 2020, v. 22, n. 2, p. 1, doi. 10.1208/s12248-020-0426-7

By:

Gonçalves, Antonio;
Mentré, France;
Lemenuel-Diot, Annabelle;
Guedj, Jérémie

Publication type:

Article

Nonlinear Mixed-Effect Models for Prostate-Specific Antigen Kinetics and Link with Survival in the Context of Metastatic Prostate Cancer: a Comparison by Simulation of Two-Stage and Joint Approaches.

Published in:

AAPS Journal, 2015, v. 17, n. 3, p. 691, doi. 10.1208/s12248-015-9745-5

By:

Desmée, Solène;
Mentré, France;
Veyrat-Follet, Christine;
Guedj, Jérémie

Publication type:

Article

Early control of viral load by favipiravir promotes survival to Ebola virus challenge and prevents cytokine storm in non-human primates.

Published in:

PLoS Neglected Tropical Diseases, 2021, v. 15, n. 3, p. 1, doi. 10.1371/journal.pntd.0009300

By:

Reynard, Stéphanie;
Gloaguen, Emilie;
Baillet, Nicolas;
Madelain, Vincent;
Guedj, Jérémie;
Raoul, Hervé;
de Lamballerie, Xavier;
Mullaert, Jimmy;
Baize, Sylvain

Publication type:

Article

Modelling HIV-1 control and remission.

Published in:

NPJ Systems Biology & Applications, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41540-024-00407-8

By:

Vemparala, Bharadwaj;
Chowdhury, Shreya;
Guedj, Jérémie;
Dixit, Narendra M.

Publication type:

Article

Reply to: 'Early HBV RNA kinetics under NA treatment may reveal new insights into HBV RNA dynamics and NA mode of action'.

Published in:

Journal of Viral Hepatitis, 2021, v. 28, n. 4, p. 689, doi. 10.1111/jvh.13470

By:

Gonçalves, Antonio;
Lemenuel‐Diot, Annabelle;
Guedj, Jérémie

Publication type:

Article

What drives the dynamics of HBV RNA during treatment?

Published in:

Journal of Viral Hepatitis, 2021, v. 28, n. 2, p. 383, doi. 10.1111/jvh.13425

By:

Gonçalves, Antonio;
Lemenuel‐Diot, Annabelle;
Cosson, Valérie;
Jin, Yuyan;
Feng, Sheng;
Bo, Qingyan;
Guedj, Jérémie

Publication type:

Article

Design evaluation and optimization for models of hepatitis C viral dynamics.

Published in:

Statistics in Medicine, 2011, v. 30, n. 10, p. 1045, doi. 10.1002/sim.4191

By:

Guedj, Jeremie;
Bazzoli, Caroline;
Neumann, Avidan U.;
Mentré, France

Publication type:

Article

Quantifying the Diversification of Hepatitis C Virus (HCV) during Primary Infection: Estimates of the In Vivo Mutation Rate.

Published in:

PLoS Pathogens, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.ppat.1002881

By:

Ribeiro, Ruy M.;
Hui Li;
Shuyi Wang;
Stoddard, Mark B.;
Learn, Gerald H.;
Korber, Bette T.;
Bhattacharya, Tanmoy;
Guedj, Jeremie;
Parrish, Erica H.;
Hahn, Beatrice H.;
Shaw, George M.;
Perelson, Alan S.

Publication type:

Article

Success of prophylactic antiviral therapy for SARS-CoV-2: Predicted critical efficacies and impact of different drug-specific mechanisms of action.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 3, p. 1, doi. 10.1371/journal.pcbi.1008752

By:

Czuppon, Peter;
Débarre, Florence;
Gonçalves, Antonio;
Tenaillon, Olivier;
Perelson, Alan S.;
Guedj, Jérémie;
Blanquart, François

Publication type:

Article

Zika virus dynamics: Effects of inoculum dose, the innate immune response and viral interference.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.pcbi.1008564

By:

Best, Katharine;
Barouch, Dan H.;
Guedj, Jeremie;
Ribeiro, Ruy M.;
Perelson, Alan S.

Publication type:

Article

Lassa viral dynamics in non-human primates treated with favipiravir or ribavirin.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.pcbi.1008535

By:

Lingas, Guillaume;
Rosenke, Kyle;
Safronetz, David;
Guedj, Jérémie

Publication type:

Article

Long-term results of laparoscopic cytoreductive surgery and HIPEC for the curative treatment of low-grade pseudomyxoma peritonei and multicystic mesothelioma.

Published in:

2020

By:

Mercier, Frederic;
Jeremie, Guedj;
Alyami, Mohammad;
Delphine, Vaudoyer;
Vahan, Kepenekian;
Pascal, Rousset;
Sylvie, Isaac;
Guillaume, Passot;
Olivier, Glehen

Publication type:

journal article

Unified approach for extrapolation and bridging of adult information in early-phase dose-finding paediatric studies.

Published in:

2018

By:

Petit, Caroline;
Samson, Adeline;
Satoshi Morita;
Ursino, Moreno;
Guedj, Jérémie;
Jullien, Vincent;
Comets, Emmanuelle;
Zohar, Sarah;
Morita, Satoshi

Publication type:

journal article

Support to early clinical decisions in drug development and personalised medicine with checkpoint inhibitors using dynamic biomarker-overall survival models.

Published in:

British Journal of Cancer, 2023, v. 129, n. 9, p. 1383, doi. 10.1038/s41416-023-02190-5

By:

Bruno, René;
Chanu, Pascal;
Kågedal, Matts;
Mercier, Francois;
Yoshida, Kenta;
Guedj, Jérémie;
Li, Chunze;
Beyer, Ulrich;
Jin, Jin Y.

Publication type:

Article

Mathematical Modeling of Bacterial Kinetics to Predict the Impact of Antibiotic Colonic Exposure and Treatment Duration on the Amount of Resistant Enterobacteria Excreted.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 9, p. 1, doi. 10.1371/journal.pcbi.1003840

By:

Nguyen, Thu Thuy;
Guedj, Jeremie;
Chachaty, Elisabeth;
de Gunzburg, Jean;
Andremont, Antoine;
Mentré, France

Publication type:

Article

Analysis of Hepatitis C Virus Decline during Treatment with the Protease Inhibitor Danoprevir Using a Multiscale Model.

Published in:

PLoS Computational Biology, 2013, v. 9, n. 3, p. 1, doi. 10.1371/journal.pcbi.1002959

By:

Rong, Libin;
Guedj, Jeremie;
Dahari, Harel;
Coffield, Jr., Daniel J.;
Levi, Micha;
Smith, Patrick;
Perelson, Alan S.

Publication type:

Article

High sera levels of SARS‐CoV‐2 N antigen are associated with death in hospitalized COVID‐19 patients.

Published in:

Journal of Medical Virology, 2023, v. 95, n. 11, p. 1, doi. 10.1002/jmv.29247

By:

Chenane, Houssem Redha;
Lingas, Guillaume;
Menidjel, Reyene;
Laouenan, Cédric;
Tubiana, Sarah;
Descamps, Diane;
Le Hingrat, Quentin;
Abel, Laurent;
Guedj, Jérémie;
Malhotra, Surbhi;
Kumar‐Singh, Samir;
Visseaux, Benoit;
Ghosn, Jade;
Charpentier, Charlotte;
Lebourgeois, Samuel

Publication type:

Article

Variant‐specific SARS‐CoV‐2 within‐host kinetics.

Published in:

Journal of Medical Virology, 2022, v. 94, n. 8, p. 3625, doi. 10.1002/jmv.27757

By:

Elie, Baptiste;
Roquebert, Bénédicte;
Sofonea, Mircea T.;
Trombert‐Paolantoni, Sabine;
Foulongne, Vincent;
Guedj, Jérémie;
Haim‐Boukobza, Stpéhanie;
Alizon, Samuel

Publication type:

Article

Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06215-z

By:

Madelain, Vincent;
Baize, Sylvain;
Jacquot, Frédéric;
Reynard, Stéphanie;
Fizet, Alexandra;
Barron, Stephane;
Solas, Caroline;
Lacarelle, Bruno;
Carbonnelle, Caroline;
Mentré, France;
Raoul, Hervé;
de Lamballerie, Xavier;
Guedj, Jérémie

Publication type:

Article

Nonlinear joint models for individual dynamic prediction of risk of death using Hamiltonian Monte Carlo: application to metastatic prostate cancer.

Published in:

2017

By:

Desmée, Solène;
Mentré, France;
Veyrat-Follet, Christine;
Sébastien, Bernard;
Guedj, Jérémie

Publication type:

journal article

Early administration of tecovirimat shortens the time to mpox clearance in a model of human infection.

Published in:

PLoS Biology, 2023, v. 21, n. 12, p. 1, doi. 10.1371/journal.pbio.3002249

By:

Nguyen, Bach Tran;
Marc, Aurélien;
Suñer, Clara;
Marks, Michael;
Ubals, Maria;
Hernández-Rodríguez, Águeda;
Melendez, María Ángeles;
Hruby, Dennis E.;
Russo, Andrew T.;
Mentré, France;
Mitjà, Oriol;
Grosenbach, Douglas W.;
Guedj, Jérémie

Publication type:

Article

Using vaccine Immunostimulation/Immunodynamic modelling methods to inform vaccine dose decision-making.

Published in:

NPJ Vaccines, 2018, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41541-018-0075-3

By:

Rhodes, Sophie J.;
Guedj, Jeremie;
Fletcher, Helen A.;
Lindenstrøm, Thomas;
Scriba, Thomas J.;
Evans, Thomas G.;
Knight, Gwenan M.;
White, Richard G.

Publication type:

Article

A New Age-Structured Multiscale Model of the Hepatitis C Virus Life-Cycle During Infection and Therapy With Direct-Acting Antiviral Agents.

Published in:

Frontiers in Microbiology, 2018, p. 1, doi. 10.3389/fmicb.2018.00601

By:

Quintela, Barbara de M.;
Conway, Jessica M.;
Hyman, James M.;
Guedj, Jeremie;
dos Santos, Rodrigo W.;
Lobosco, Marcelo;
Perelson, Alan S.

Publication type:

Article

Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21992-w

By:

Driouich, Jean-Sélim;
Cochin, Maxime;
Lingas, Guillaume;
Moureau, Grégory;
Touret, Franck;
Petit, Paul-Rémi;
Piorkowski, Géraldine;
Barthélémy, Karine;
Laprie, Caroline;
Coutard, Bruno;
Guedj, Jérémie;
de Lamballerie, Xavier;
Solas, Caroline;
Nougairède, Antoine

Publication type:

Article

Nonlinear multilevel joint model for individual lesion kinetics and survival to characterize intra‐individual heterogeneity in patients with advanced cancer.

Published in:

Biometrics, 2023, v. 79, n. 4, p. 3752, doi. 10.1111/biom.13912

By:

Kerioui, Marion;
Beaulieu, Maxime;
Desmée, Solène;
Bertrand, Julie;
Mercier, François;
Jin, Jin Y.;
Bruno, René;
Guedj, Jérémie

Publication type:

Article

Using the SAEM algorithm for mechanistic joint models characterizing the relationship between nonlinear PSA kinetics and survival in prostate cancer patients.

Published in:

Biometrics, 2017, v. 73, n. 1, p. 305, doi. 10.1111/biom.12537

By:

Desmée, Solène;
Mentré, France;
Veyrat‐Follet, Christine;
Sébastien, Bernard;
Guedj, Jérémie

Publication type:

Article

Joint Modeling of the Clinical Progression and of the Biomarkers' Dynamics Using a Mechanistic Model.

Published in:

Biometrics, 2011, v. 67, n. 1, p. 59, doi. 10.1111/j.1541-0420.2010.01418.x

By:

Guedj, Jeremie;
Thiébaut, Rodolphe;
Commenges, Daniel

Publication type:

Article

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques.

Published in:

2018

By:

Guedj, Jérémie;
Piorkowski, Géraldine;
Jacquot, Frédéric;
Madelain, Vincent;
Nguyen, Thi Huyen Tram;
Rodallec, Anne;
Gunther, Stephan;
Carbonnelle, Caroline;
Mentré, France;
Raoul, Hervé;
de Lamballerie, Xavier

Publication type:

journal article

Tumor growth and overall survival modeling to support decision making in phase Ib/II trials: A comparison of the joint and two‐stage approaches.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 6, p. 1017, doi. 10.1002/psp4.13137

By:

Marchand, Mathilde;
Gonçalves, Antonio;
Mercier, François;
Chanu, Pascal;
Jin, Jin Y.;
Guedj, Jérémie;
Bruno, René

Publication type:

Article

Comparison of two‐stage and joint TGI‐OS modeling using data from six atezolizumab clinical studies in patients with metastatic non‐small cell lung cancer.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 1, p. 68, doi. 10.1002/psp4.13057

By:

Gonçalves, Antonio;
Marchand, Mathilde;
Chan, Phyllis;
Jin, Jin Y.;
Guedj, Jérémie;
Bruno, René

Publication type:

Article

Association between SARS‐CoV‐2 viral kinetics and clinical score evolution in hospitalized patients.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 12, p. 2027, doi. 10.1002/psp4.13051

By:

Néant, Nadège;
Lingas, Guillaume;
Gaymard, Alexandre;
Belhadi, Drifa;
Hites, Maya;
Staub, Thérèse;
Greil, Richard;
Paiva, Jose‐Artur;
Poissy, Julien;
Peiffer‐Smadja, Nathan;
Costagliola, Dominique;
Yazdanpanah, Yazdan;
Bouscambert‐Duchamp, Maude;
Gagneux‐Brunon, Amandine;
Ader, Florence;
Mentré, France;
Wallet, Florent;
Burdet, Charles;
Guedj, Jérémie

Publication type:

Article

Modeling the bacterial dynamics in the gut microbiota following an antibiotic‐induced perturbation.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 7, p. 906, doi. 10.1002/psp4.12806

By:

Guk, Jinju;
Bridier‐Nahmias, Antoine;
Magnan, Mélanie;
Grall, Nathalie;
Duval, Xavier;
Clermont, Olivier;
Ruppé, Etienne;
d'Humières, Camille;
Tenaillon, Olivier;
Denamur, Erick;
Mentré, France;
Guedj, Jérémie;
Burdet, Charles

Publication type:

Article

Timing of Antiviral Treatment Initiation is Critical to Reduce SARS‐CoV‐2 Viral Load.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 9, p. 509, doi. 10.1002/psp4.12543

By:

Gonçalves, Antonio;
Bertrand, Julie;
Ke, Ruian;
Comets, Emmanuelle;
Lamballerie, Xavier;
Malvy, Denis;
Pizzorno, Andrés;
Terrier, Olivier;
Rosa Calatrava, Manuel;
Mentré, France;
Smith, Patrick;
Perelson, Alan S.;
Guedj, Jérémie

Publication type:

Article

Modeling Favipiravir Antiviral Efficacy Against Emerging Viruses: From Animal Studies to Clinical Trials.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 5, p. 258, doi. 10.1002/psp4.12510

By:

Madelain, Vincent;
Mentré, France;
Baize, Sylvain;
Anglaret, Xavier;
Laouénan, Cédric;
Oestereich, Lisa;
Nguyen, Thi Huyen Tram;
Malvy, Denis;
Piorkowski, Géraldine;
Graw, Frederik;
Günther, Stephan;
Raoul, Hervé;
Lamballerie, Xavier;
Guedj, Jérémie

Publication type:

Article