Works by Guedj, Jérémie

Results: 42

Ebola Virus Infection: Review of the Pharmacokinetic and Pharmacodynamic Properties of Drugs Considered for Testing in Human Efficacy Trials.

Published in:

2016

By:

Madelain, Vincent;
Nguyen, Thi;
Olivo, Anaelle;
Lamballerie, Xavier;
Guedj, Jérémie;
Taburet, Anne-Marie;
Mentré, France;
Nguyen, Thi Huyen Tram;
de Lamballerie, Xavier;
Guedj, Jérémie;
Mentré, France

Publication type:

journal article

Neutralizing Antibody Levels as a Correlate of Protection Against SARS‐CoV‐2 Infection: A Modeling Analysis.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 1, p. 86, doi. 10.1002/cpt.3069

By:

Lingas, Guillaume;
Planas, Delphine;
Péré, Hélène;
Porrot, Françoise;
Guivel‐Benhassine, Florence;
Staropoli, Isabelle;
Duffy, Darragh;
Chapuis, Nicolas;
Gobeaux, Camille;
Veyer, David;
Delaugerre, Constance;
Le Goff, Jérôme;
Getten, Prunelle;
Hadjadj, Jérôme;
Bellino, Adèle;
Parfait, Béatrice;
Treluyer, Jean‐Marc;
Schwartz, Olivier;
Guedj, Jérémie;
Kernéis, Solen

Publication type:

Article

A Semi‐mechanistic Model to Characterize the Long‐Term Dynamics of Hepatitis B Virus Markers During Treatment With Lamivudine and Pegylated Interferon.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 2, p. 390, doi. 10.1002/cpt.2798

By:

El Messaoudi, Selma;
Lemenuel‐Diot, Annabelle;
Gonçalves, Antonio;
Guedj, Jérémie

Publication type:

Article

Modeling the Effect of DAV132, a Novel Colon‐Targeted Adsorbent, on Fecal Concentrations of Moxifloxacin and Gut Microbiota Diversity in Healthy Volunteers.

Published in:

Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 1045, doi. 10.1002/cpt.1977

By:

Guk, Jinju;
Guedj, Jérémie;
Burdet, Charles;
Andremont, Antoine;
Gunzburg, Jean;
Ducher, Annie;
Mentré, France

Publication type:

Article

Dose Rationale for Favipiravir Use in Patients Infected With SARS‐CoV‐2.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 2, p. 188, doi. 10.1002/cpt.1877

By:

Eloy, Philippine;
Solas, Caroline;
Touret, Franck;
Mentré, France;
Malvy, Denis;
Lamballerie, Xavier;
Guedj, Jérémie

Publication type:

Article

Association Between Tumor Size Kinetics and Survival in Patients With Urothelial Carcinoma Treated With Atezolizumab: Implication for Patient Follow‐Up.

Published in:

Clinical Pharmacology & Therapeutics, 2019, v. 106, n. 4, p. 810, doi. 10.1002/cpt.1450

By:

Tardivon, Coralie;
Desmée, Solène;
Kerioui, Marion;
Bruno, René;
Wu, Benjamin;
Mentré, France;
Mercier, François;
Guedj, Jérémie

Publication type:

Article

Survival of SARS-CoV-2 on Non-Porous Materials in an Experimental Setting Representative of Fomites.

Published in:

Coatings (2079-6412), 2021, v. 11, n. 4, p. 371, doi. 10.3390/coatings11040371

By:

Bonil, Laura;
Lingas, Guillaume;
Coupeau, Damien;
Lucet, Jean-Christophe;
Guedj, Jérémie;
Visseaux, Benoît;
Muylkens, Benoît

Publication type:

Article

Modelling the effectiveness of antiviral treatment strategies to prevent household transmission of acute respiratory viruses.

Published in:

PLoS Computational Biology, 2024, v. 20, n. 12, p. 1, doi. 10.1371/journal.pcbi.1012573

By:

Zaaraoui, Hind;
Schumer, Clarisse;
Duval, Xavier;
Hoen, Bruno;
Opatowski, Lulla;
Guedj, Jérémie

Publication type:

Article

Modelling the association between biomarkers and clinical outcome: An introduction to nonlinear joint models.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 4, p. 1452, doi. 10.1111/bcp.15200

By:

Kerioui, Marion;
Bertrand, Julie;
Bruno, René;
Mercier, François;
Guedj, Jérémie;
Desmée, Solène

Publication type:

Article

Model Averaging in Viral Dynamic Models.

Published in:

AAPS Journal, 2020, v. 22, n. 2, p. 1, doi. 10.1208/s12248-020-0426-7

By:

Gonçalves, Antonio;
Mentré, France;
Lemenuel-Diot, Annabelle;
Guedj, Jérémie

Publication type:

Article

Nonlinear Mixed-Effect Models for Prostate-Specific Antigen Kinetics and Link with Survival in the Context of Metastatic Prostate Cancer: a Comparison by Simulation of Two-Stage and Joint Approaches.

Published in:

AAPS Journal, 2015, v. 17, n. 3, p. 691, doi. 10.1208/s12248-015-9745-5

By:

Desmée, Solène;
Mentré, France;
Veyrat-Follet, Christine;
Guedj, Jérémie

Publication type:

Article

Early control of viral load by favipiravir promotes survival to Ebola virus challenge and prevents cytokine storm in non-human primates.

Published in:

PLoS Neglected Tropical Diseases, 2021, v. 15, n. 3, p. 1, doi. 10.1371/journal.pntd.0009300

By:

Reynard, Stéphanie;
Gloaguen, Emilie;
Baillet, Nicolas;
Madelain, Vincent;
Guedj, Jérémie;
Raoul, Hervé;
de Lamballerie, Xavier;
Mullaert, Jimmy;
Baize, Sylvain

Publication type:

Article

Modelling HIV-1 control and remission.

Published in:

NPJ Systems Biology & Applications, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41540-024-00407-8

By:

Vemparala, Bharadwaj;
Chowdhury, Shreya;
Guedj, Jérémie;
Dixit, Narendra M.

Publication type:

Article

Reply to: 'Early HBV RNA kinetics under NA treatment may reveal new insights into HBV RNA dynamics and NA mode of action'.

Published in:

Journal of Viral Hepatitis, 2021, v. 28, n. 4, p. 689, doi. 10.1111/jvh.13470

By:

Gonçalves, Antonio;
Lemenuel‐Diot, Annabelle;
Guedj, Jérémie

Publication type:

Article

What drives the dynamics of HBV RNA during treatment?

Published in:

Journal of Viral Hepatitis, 2021, v. 28, n. 2, p. 383, doi. 10.1111/jvh.13425

By:

Gonçalves, Antonio;
Lemenuel‐Diot, Annabelle;
Cosson, Valérie;
Jin, Yuyan;
Feng, Sheng;
Bo, Qingyan;
Guedj, Jérémie

Publication type:

Article

Success of prophylactic antiviral therapy for SARS-CoV-2: Predicted critical efficacies and impact of different drug-specific mechanisms of action.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 3, p. 1, doi. 10.1371/journal.pcbi.1008752

By:

Czuppon, Peter;
Débarre, Florence;
Gonçalves, Antonio;
Tenaillon, Olivier;
Perelson, Alan S.;
Guedj, Jérémie;
Blanquart, François

Publication type:

Article

Lassa viral dynamics in non-human primates treated with favipiravir or ribavirin.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.pcbi.1008535

By:

Lingas, Guillaume;
Rosenke, Kyle;
Safronetz, David;
Guedj, Jérémie

Publication type:

Article

Unified approach for extrapolation and bridging of adult information in early-phase dose-finding paediatric studies.

Published in:

2018

By:

Petit, Caroline;
Samson, Adeline;
Satoshi Morita;
Ursino, Moreno;
Guedj, Jérémie;
Jullien, Vincent;
Comets, Emmanuelle;
Zohar, Sarah;
Morita, Satoshi

Publication type:

journal article

Support to early clinical decisions in drug development and personalised medicine with checkpoint inhibitors using dynamic biomarker-overall survival models.

Published in:

British Journal of Cancer, 2023, v. 129, n. 9, p. 1383, doi. 10.1038/s41416-023-02190-5

By:

Bruno, René;
Chanu, Pascal;
Kågedal, Matts;
Mercier, Francois;
Yoshida, Kenta;
Guedj, Jérémie;
Li, Chunze;
Beyer, Ulrich;
Jin, Jin Y.

Publication type:

Article

High sera levels of SARS‐CoV‐2 N antigen are associated with death in hospitalized COVID‐19 patients.

Published in:

Journal of Medical Virology, 2023, v. 95, n. 11, p. 1, doi. 10.1002/jmv.29247

By:

Chenane, Houssem Redha;
Lingas, Guillaume;
Menidjel, Reyene;
Laouenan, Cédric;
Tubiana, Sarah;
Descamps, Diane;
Le Hingrat, Quentin;
Abel, Laurent;
Guedj, Jérémie;
Malhotra, Surbhi;
Kumar‐Singh, Samir;
Visseaux, Benoit;
Ghosn, Jade;
Charpentier, Charlotte;
Lebourgeois, Samuel

Publication type:

Article

Variant‐specific SARS‐CoV‐2 within‐host kinetics.

Published in:

Journal of Medical Virology, 2022, v. 94, n. 8, p. 3625, doi. 10.1002/jmv.27757

By:

Elie, Baptiste;
Roquebert, Bénédicte;
Sofonea, Mircea T.;
Trombert‐Paolantoni, Sabine;
Foulongne, Vincent;
Guedj, Jérémie;
Haim‐Boukobza, Stpéhanie;
Alizon, Samuel

Publication type:

Article

Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06215-z

By:

Madelain, Vincent;
Baize, Sylvain;
Jacquot, Frédéric;
Reynard, Stéphanie;
Fizet, Alexandra;
Barron, Stephane;
Solas, Caroline;
Lacarelle, Bruno;
Carbonnelle, Caroline;
Mentré, France;
Raoul, Hervé;
de Lamballerie, Xavier;
Guedj, Jérémie

Publication type:

Article

Nonlinear joint models for individual dynamic prediction of risk of death using Hamiltonian Monte Carlo: application to metastatic prostate cancer.

Published in:

2017

By:

Desmée, Solène;
Mentré, France;
Veyrat-Follet, Christine;
Sébastien, Bernard;
Guedj, Jérémie

Publication type:

journal article

Early administration of tecovirimat shortens the time to mpox clearance in a model of human infection.

Published in:

PLoS Biology, 2023, v. 21, n. 12, p. 1, doi. 10.1371/journal.pbio.3002249

By:

Nguyen, Bach Tran;
Marc, Aurélien;
Suñer, Clara;
Marks, Michael;
Ubals, Maria;
Hernández-Rodríguez, Águeda;
Melendez, María Ángeles;
Hruby, Dennis E.;
Russo, Andrew T.;
Mentré, France;
Mitjà, Oriol;
Grosenbach, Douglas W.;
Guedj, Jérémie

Publication type:

Article

Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21992-w

By:

Driouich, Jean-Sélim;
Cochin, Maxime;
Lingas, Guillaume;
Moureau, Grégory;
Touret, Franck;
Petit, Paul-Rémi;
Piorkowski, Géraldine;
Barthélémy, Karine;
Laprie, Caroline;
Coutard, Bruno;
Guedj, Jérémie;
de Lamballerie, Xavier;
Solas, Caroline;
Nougairède, Antoine

Publication type:

Article

Nonlinear multilevel joint model for individual lesion kinetics and survival to characterize intra‐individual heterogeneity in patients with advanced cancer.

Published in:

Biometrics, 2023, v. 79, n. 4, p. 3752, doi. 10.1111/biom.13912

By:

Kerioui, Marion;
Beaulieu, Maxime;
Desmée, Solène;
Bertrand, Julie;
Mercier, François;
Jin, Jin Y.;
Bruno, René;
Guedj, Jérémie

Publication type:

Article

Using the SAEM algorithm for mechanistic joint models characterizing the relationship between nonlinear PSA kinetics and survival in prostate cancer patients.

Published in:

Biometrics, 2017, v. 73, n. 1, p. 305, doi. 10.1111/biom.12537

By:

Desmée, Solène;
Mentré, France;
Veyrat‐Follet, Christine;
Sébastien, Bernard;
Guedj, Jérémie

Publication type:

Article

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques.

Published in:

2018

By:

Guedj, Jérémie;
Piorkowski, Géraldine;
Jacquot, Frédéric;
Madelain, Vincent;
Nguyen, Thi Huyen Tram;
Rodallec, Anne;
Gunther, Stephan;
Carbonnelle, Caroline;
Mentré, France;
Raoul, Hervé;
de Lamballerie, Xavier

Publication type:

journal article

Tumor growth and overall survival modeling to support decision making in phase Ib/II trials: A comparison of the joint and two‐stage approaches.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 6, p. 1017, doi. 10.1002/psp4.13137

By:

Marchand, Mathilde;
Gonçalves, Antonio;
Mercier, François;
Chanu, Pascal;
Jin, Jin Y.;
Guedj, Jérémie;
Bruno, René

Publication type:

Article

Comparison of two‐stage and joint TGI‐OS modeling using data from six atezolizumab clinical studies in patients with metastatic non‐small cell lung cancer.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 1, p. 68, doi. 10.1002/psp4.13057

By:

Gonçalves, Antonio;
Marchand, Mathilde;
Chan, Phyllis;
Jin, Jin Y.;
Guedj, Jérémie;
Bruno, René

Publication type:

Article

Association between SARS‐CoV‐2 viral kinetics and clinical score evolution in hospitalized patients.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 12, p. 2027, doi. 10.1002/psp4.13051

By:

Néant, Nadège;
Lingas, Guillaume;
Gaymard, Alexandre;
Belhadi, Drifa;
Hites, Maya;
Staub, Thérèse;
Greil, Richard;
Paiva, Jose‐Artur;
Poissy, Julien;
Peiffer‐Smadja, Nathan;
Costagliola, Dominique;
Yazdanpanah, Yazdan;
Bouscambert‐Duchamp, Maude;
Gagneux‐Brunon, Amandine;
Ader, Florence;
Mentré, France;
Wallet, Florent;
Burdet, Charles;
Guedj, Jérémie

Publication type:

Article

Modeling the bacterial dynamics in the gut microbiota following an antibiotic‐induced perturbation.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 7, p. 906, doi. 10.1002/psp4.12806

By:

Guk, Jinju;
Bridier‐Nahmias, Antoine;
Magnan, Mélanie;
Grall, Nathalie;
Duval, Xavier;
Clermont, Olivier;
Ruppé, Etienne;
d'Humières, Camille;
Tenaillon, Olivier;
Denamur, Erick;
Mentré, France;
Guedj, Jérémie;
Burdet, Charles

Publication type:

Article

Timing of Antiviral Treatment Initiation is Critical to Reduce SARS‐CoV‐2 Viral Load.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 9, p. 509, doi. 10.1002/psp4.12543

By:

Gonçalves, Antonio;
Bertrand, Julie;
Ke, Ruian;
Comets, Emmanuelle;
Lamballerie, Xavier;
Malvy, Denis;
Pizzorno, Andrés;
Terrier, Olivier;
Rosa Calatrava, Manuel;
Mentré, France;
Smith, Patrick;
Perelson, Alan S.;
Guedj, Jérémie

Publication type:

Article

Modeling Favipiravir Antiviral Efficacy Against Emerging Viruses: From Animal Studies to Clinical Trials.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 5, p. 258, doi. 10.1002/psp4.12510

By:

Madelain, Vincent;
Mentré, France;
Baize, Sylvain;
Anglaret, Xavier;
Laouénan, Cédric;
Oestereich, Lisa;
Nguyen, Thi Huyen Tram;
Malvy, Denis;
Piorkowski, Géraldine;
Graw, Frederik;
Günther, Stephan;
Raoul, Hervé;
Lamballerie, Xavier;
Guedj, Jérémie

Publication type:

Article

Favipiravir pharmacokinetics in Ebola-Infected patients of the JIKI trial reveals concentrations lower than targeted.

Published in:

PLoS Neglected Tropical Diseases, 2017, v. 11, n. 2, p. 1, doi. 10.1371/journal.pntd.0005389

By:

Nguyen, Thi Huyen Tram;
Guedj, Jérémie;
Anglaret, Xavier;
Laouénan, Cédric;
Madelain, Vincent;
Taburet, Anne-Marie;
Baize, Sylvain;
Sissoko, Daouda;
Pastorino, Boris;
Rodallec, Anne;
Piorkowski, Géraldine;
Carazo, Sara;
Conde, Mamoudou N.;
Gala, Jean-Luc;
Bore, Joseph Akoi;
Carbonnelle, Caroline;
Jacquot, Frédéric;
Raoul, Hervé;
Malvy, Denis;
de Lamballerie, Xavier

Publication type:

Article

Bayesian inference using Hamiltonian Monte-Carlo algorithm for nonlinear joint modeling in the context of cancer immunotherapy.

Published in:

2020

By:

Kerioui, Marion;
Mercier, Francois;
Bertrand, Julie;
Tardivon, Coralie;
Bruno, René;
Guedj, Jérémie;
Desmée, Solène

Publication type:

journal article

Antiviral effect of Evusheld in COVID-19 hospitalized patients infected with pre-omicron or omicron variants: a modelling analysis of the randomized DisCoVeRy trial—authors' response.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2025, v. 80, n. 3, p. 892, doi. 10.1093/jac/dkae447

By:

Beaulieu, Maxime;
Guedj, Jérémie

Publication type:

Article

Antiviral effect of Evusheld in COVID-19 hospitalized patients infected with pre-Omicron or Omicron variants: a modelling analysis of the randomized DisCoVeRy trial.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 11, p. 2887, doi. 10.1093/jac/dkae301

By:

Beaulieu, Maxime;
Gaymard, Alexandre;
Massonnaud, Clément;
Peiffer-Smadja, Nathan;
Bouscambert-Duchamp, Maude;
Carcelain, Guislaine;
Lingas, Guillaume;
Mentré, France;
Ader, Florence;
Hites, Maya;
Poignard, Pascal;
Guedj, Jérémie

Publication type:

Article

Effect of remdesivir on viral dynamics in COVID-19 hospitalized patients: a modelling analysis of the randomized, controlled, open-label DisCoVeRy trial.

Published in:

2022

By:

Lingas, Guillaume;
Néant, Nadège;
Gaymard, Alexandre;
Belhadi, Drifa;
Peytavin, Gilles;
Hites, Maya;
Staub, Thérèse;
Greil, Richard;
Paiva, Jose-Artur;
Poissy, Julien;
Peiffer-Smadja, Nathan;
Costagliola, Dominique;
Yazdanpanah, Yazdan;
Wallet, Florent;
Gagneux-Brunon, Amandine;
Mentré, France;
Ader, Florence;
Burdet, Charles;
Guedj, Jérémie;
Bouscambert-Duchamp, Maude

Publication type:

Journal Article

Antiviral capacity of the early CD8 T-cell response is predictive of natural control of SIV infection: Learning in vivo dynamics using ex vivo data.

Published in:

PLoS Computational Biology, 2024, v. 20, n. 9, p. 1, doi. 10.1371/journal.pcbi.1012434

By:

Vemparala, Bharadwaj;
Madelain, Vincent;
Passaes, Caroline;
Millet, Antoine;
Avettand-Fenoel, Véronique;
Djidjou-Demasse, Ramsès;
Dereuddre-Bosquet, Nathalie;
Le Grand, Roger;
Rouzioux, Christine;
Vaslin, Bruno;
Sáez-Cirión, Asier;
Guedj, Jérémie;
Dixit, Narendra M.

Publication type:

Article

Impact of variants of concern on SARS-CoV-2 viral dynamics in non-human primates.

Published in:

PLoS Computational Biology, 2023, v. 19, n. 8, p. 1, doi. 10.1371/journal.pcbi.1010721

By:

Marc, Aurélien;
Marlin, Romain;
Donati, Flora;
Prague, Mélanie;
Kerioui, Marion;
Hérate, Cécile;
Alexandre, Marie;
Dereuddre-bosquet, Nathalie;
Bertrand, Julie;
Contreras, Vanessa;
Behillil, Sylvie;
Maisonnasse, Pauline;
Van Der Werf, Sylvie;
Le Grand, Roger;
Guedj, Jérémie

Publication type:

Article

Modeling the kinetics of the neutralizing antibody response against SARS-CoV-2 variants after several administrations of Bnt162b2.

Published in:

PLoS Computational Biology, 2023, v. 19, n. 8, p. 1, doi. 10.1371/journal.pcbi.1011282

By:

Clairon, Quentin;
Prague, Mélanie;
Planas, Delphine;
Bruel, Timothée;
Hocqueloux, Laurent;
Prazuck, Thierry;
Schwartz, Olivier;
Thiébaut, Rodolphe;
Guedj, Jérémie

Publication type:

Article