Works matching AU Guchelaar, Henk-Jan

Results: 164

Formulation, Quality Control and Shelf Life of the Experimental Cytostatic Drug Cyclopentenyl Cytosine.

Published in:

Drug Development & Industrial Pharmacy, 2006, v. 32, n. 4, p. 497, doi. 10.1080/03639040500529150

By:

Schimmel, Kirsten;
Guchelaar, Henk-Jan;
van Kan, Erik

Publication type:

Article

Phenoconversion of Cytochrome P450 Metabolism: A Systematic Review.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 9, p. 2890, doi. 10.3390/jcm9092890

By:

Klomp, Sylvia D.;
Manson, Martijn L.;
Guchelaar, Henk-Jan;
Swen, Jesse J.

Publication type:

Article

Assessing the Implementation of Pharmacogenomic Panel-Testing in Primary Care in the Netherlands Utilizing a Theoretical Framework.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 3, p. 814, doi. 10.3390/jcm9030814

By:

van der Wouden, Cathelijne H.;
Paasman, Ellen;
Teichert, Martina;
Crone, Matty R.;
Guchelaar, Henk-Jan;
Swen, Jesse J.

Publication type:

Article

First insights into the current practice, knowledge, and attitudes of community pharmacists regarding sexual adverse drug reactions: a cross-sectional survey.

Published in:

Sexual Medicine, 2023, v. 11, n. 1, p. 1, doi. 10.1093/sexmed/qfac014

By:

Gordijn, Rineke;
Nicolai, Melianthe P. J.;
Elzevier, Henk W.;
Guchelaar, Henk-Jan;
Teichert, Martina

Publication type:

Article

An estimation of patients at potential risk for drug-induced sexual dysfunction using pharmacy dispensing data.

Published in:

2021

By:

Gordijn, Rineke;
Nicolai, Melianthe P J;
Elzevier, Henk W;
Guchelaar, Henk-Jan;
Teichert, Martina

Publication type:

journal article

A computerized adverse drug event alerting system using clinical rules: a retrospective and prospective comparison with conventional medication surveillance in the Netherlands.

Published in:

2011

By:

Rommers MK;
Teepe-Twiss IM;
Guchelaar HJ;
Rommers, Mirjam K;
Teepe-Twiss, Irene M;
Guchelaar, Henk-Jan

Publication type:

journal article

Application of the Bow-Tie model in medication safety risk analysis: consecutive experience in two hospitals in the Netherlands.

Published in:

2009

By:

Wierenga PC;
Lie-A-Huen L;
de Rooij SE;
Klazinga NS;
Guchelaar HJ;
Smorenburg SM;
Wierenga, Peter C;
Lie-A-Huen, Loraine;
de Rooij, Sophia E;
Klazinga, Niek S;
Guchelaar, Henk-Jan;
Smorenburg, Susanne M

Publication type:

journal article

Pharmacogenomics decision support in the U-PGx project: Results and advice from clinical implementation across seven European countries.

Published in:

PLoS ONE, 2022, v. 17, n. 6, p. 1, doi. 10.1371/journal.pone.0268534

By:

Blagec, Kathrin;
Swen, Jesse J.;
Koopmann, Rudolf;
Cheung, Ka-Chun;
Crommentuijn - van Rhenen, Mandy;
Holsappel, Inge;
Konta, Lidija;
Ott, Simon;
Steinberger, Daniela;
Xu, Hong;
Cecchin, Erika;
Dolžan, Vita;
Dávila-Fajardo, Cristina Lucía;
Patrinos, George P.;
Sunder-Plassmann, Gere;
Turner, Richard M.;
Pirmohamed, Munir;
Guchelaar, Henk-Jan;
Samwald, Matthias

Publication type:

Article

A systematic review on pharmacogenetics in cardiovascular disease: is it ready for clinical application?

Published in:

European Heart Journal, 2012, v. 33, n. 2, p. 165, doi. 10.1093/eurheartj/ehr239

By:

Verschuren, Jeffrey J.W.;
Trompet, Stella;
Wessels, Judith A.M.;
Guchelaar, Henk-Jan;
de Maat, Moniek P.M.;
Simoons, Maarten L.;
Jukema, J. Wouter

Publication type:

Article

Genotypes of CYP2C8 and FGD4 and their association with peripheral neuropathy or early dose reduction in paclitaxel-treated breast cancer patients.

Published in:

2016

By:

Lam, Siu W;
Frederiks, Charlotte N;
van der Straaten, Tahar;
Honkoop, Aafke H;
Guchelaar, Henk-Jan;
Boven, Epie

Publication type:

journal article

Improved Prediction of CYP2D6 Catalyzed Drug Metabolism by Taking Variant Substrate Specificities and Novel Polymorphic Haplotypes into Account.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 118, n. 1, p. 218, doi. 10.1002/cpt.3680

By:

Johansson, Inger;
Xanthopoulou, Emmanouella M.;
Zhou, Yitian;
Sanchez‐Spitman, Anabel;
van der Lee, Maaike;
Wollmann, Birgit M.;
Størset, Elisabet;
Swen, Jesse J.;
Guchelaar, Henk‐Jan;
Molden, Espen;
Jukic, Marin M.;
Ingelman‐Sundberg, Magnus

Publication type:

Article

Mapping the Pharmacogenetic Landscape in a Ugandan Population: Implications for Personalized Medicine in an Underrepresented Population.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 4, p. 980, doi. 10.1002/cpt.3309

By:

Samarasinghe, Sumudu Rangika;
Lee, Seung‐been;
Corpas, Manuel;
Fatumo, Segun;
Guchelaar, Henk‐Jan;
Nagaraj, Shivashankar H.

Publication type:

Article

Nonlinear Mixed‐Effects Model of Z‐Endoxifen Concentrations in Tamoxifen‐Treated Patients from the CEPAM Cohort.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 3, p. 690, doi. 10.1002/cpt.3238

By:

Mc Laughlin, Anna M.;
Helland, Thomas;
Klima, Fenja;
Koolen, Stijn L.W.;
van Schaik, Ron H.N.;
Mathijssen, Ron H.J.;
Neven, Patrick;
Swen, Jesse J.;
Guchelaar, Henk‐Jan;
Dalenc, Florence;
White‐Koning, Melanie;
Michelet, Robin;
Mikus, Gerd;
Schroth, Werner;
Mürdter, Thomas;
Brauch, Hiltrud;
Schwab, Matthias;
Søiland, Håvard;
Mellgren, Gunnar;
Thomas, Fabienne

Publication type:

Article

A Genome‐Wide Association Study of Endoxifen Serum Concentrations and Adjuvant Tamoxifen Efficacy in Early‐Stage Breast Cancer Patients.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 1, p. 155, doi. 10.1002/cpt.3255

By:

Sanchez‐Spitman, Anabel Beatriz;
Böhringer, Stefan;
Dezentjé, Vincent Olaf;
Gelderblom, Hans;
Swen, Jesse Joachim;
Guchelaar, Henk‐Jan

Publication type:

Article

Personalized Chronomodulated 5‐Fluorouracil Treatment: A Physiologically‐Based Pharmacokinetic Precision Dosing Approach for Optimizing Cancer Therapy.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 6, p. 1282, doi. 10.1002/cpt.3181

By:

Marok, Fatima Zahra;
Wojtyniak, Jan‐Georg;
Selzer, Dominik;
Dallmann, Robert;
Swen, Jesse J.;
Guchelaar, Henk‐Jan;
Schwab, Matthias;
Lehr, Thorsten

Publication type:

Article

A Nomogram to Predict Severe Toxicity in DPYD Wild‐Type Patients Treated With Capecitabine‐Based Anticancer Regimens.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 2, p. 269, doi. 10.1002/cpt.3100

By:

Knikman, Jonathan E.;
Lopez‐Yurda, Marta;
Meulendijks, Didier;
Deenen, Maarten J.;
Schellens, Jan H.M.;
Beijnen, Jos;
Cats, Annemieke;
Guchelaar, Henk‐Jan

Publication type:

Article

Development and Bioequivalence of 3D‐Printed Medication at the Point‐of‐Care: Bridging the Gap Toward Personalized Medicine.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 5, p. 1125, doi. 10.1002/cpt.2870

By:

Lyousoufi, Maryam;
Lafeber, Iris;
Kweekel, Dinemarie;
de Winter, Brenda C. M.;
Swen, Jesse J.;
Le Brun, Paul P. H.;
Bijleveld‐Olierook, Erica C. M.;
van Gelder, Teun;
Guchelaar, Henk‐Jan;
Moes, Dirk Jan A. R.;
Schimmel, Kirsten J. M.

Publication type:

Article

Genome‐wide Association Study of Methotrexate‐Induced Liver Injury in Rheumatoid Arthritis Patients.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 4, p. 916, doi. 10.1002/cpt.2858

By:

Eektimmerman, Frank;
Swen, Jesse J.;
den Broeder, Alfons A.;
Hazes, Johanna M. W.;
Kurreeman, Fina S.;
Verstappen, Suzanne M. M.;
Nair, Nisha;
Pawlik, Andrzej;
Nurmohamed, Mike T.;
Dolžan, Vita;
Böhringer, Stefan;
Allaart, Cornelia F.;
Guchelaar, Henk‐Jan

Publication type:

Article

Response to "Plasma Uracil as a DPD Phenotyping Test: Pre‐analytical Handling Matters".

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 3, p. 473, doi. 10.1002/cpt.2775

By:

de With, Mirjam;
Knikman, Jonathan;
Schellens, Jan H. M.;
Gelderblom, Hans;
Cats, Annemieke;
Guchelaar, Henk‐Jan;
Mathijssen, Ron H. J.;
Swen, Jesse J.;
Meulendijks, Didier

Publication type:

Article

Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study.

Published in:

Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 1, p. 62, doi. 10.1002/cpt.2608

By:

de With, Mirjam;
Knikman, Jonathan;
de Man, Femke M.;
Lunenburg, Carin A. T. C.;
Henricks, Linda M.;
van Kuilenburg, André B. P.;
Maring, Jan G.;
van Staveren, Maurice C.;
de Vries, Niels;
Rosing, Hilde;
Beijnen, Jos H.;
Pluim, Dick;
Modak, Anil;
Imholz, Alex L. T.;
van Schaik, Ron H. N.;
Schellens, Jan H. M.;
Gelderblom, Hans;
Cats, Annemieke;
Guchelaar, Henk‐Jan;
Mathijssen, Ron H. J.

Publication type:

Article

Individualized Dosing of Fluoropyrimidine‐Based Chemotherapy to Prevent Severe Fluoropyrimidine‐Related Toxicity: What Are the Options?

Published in:

Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 3, p. 591, doi. 10.1002/cpt.2069

By:

Knikman, Jonathan E.;
Gelderblom, Hans;
Beijnen, Jos H.;
Cats, Annemieke;
Guchelaar, Henk‐Jan;
Henricks, Linda M.

Publication type:

Article

An Electronic Health Record Text Mining Tool to Collect Real‐World Drug Treatment Outcomes: A Validation Study in Patients With Metastatic Renal Cell Carcinoma.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 3, p. 644, doi. 10.1002/cpt.1966

By:

Laar, Sylvia A.;
Gombert‐Handoko, Kim B.;
Guchelaar, Henk‐Jan;
Zwaveling, Juliëtte

Publication type:

Article

Repurposing of Diagnostic Whole Exome Sequencing Data of 1,583 Individuals for Clinical Pharmacogenetics.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 3, p. 617, doi. 10.1002/cpt.1665

By:

Lee, Maaike;
Allard, William G.;
Bollen, Sander;
Santen, Gijs W. E.;
Ruivenkamp, Claudia A. L.;
Hoffer, Mariëtte J. V.;
Kriek, Marjolein;
Guchelaar, Henk‐Jan;
Anvar, Seyed Y.;
Swen, Jesse J.

Publication type:

Article

Development of the PGx‐Passport: A Panel of Actionable Germline Genetic Variants for Pre‐Emptive Pharmacogenetic Testing.

Published in:

Clinical Pharmacology & Therapeutics, 2019, v. 106, n. 4, p. 866, doi. 10.1002/cpt.1489

By:

Wouden, Cathelijne H.;
van Rhenen, Mandy H.;
Jama, Wafa O.M.;
Ingelman‐Sundberg, Magnus;
Lauschke, Volker M.;
Konta, Lidija;
Schwab, Matthias;
Swen, Jesse J.;
Guchelaar, Henk‐Jan

Publication type:

Article

Real-world evaluation of supportive care using an electronic health record text-mining tool: G-CSF use in breast cancer patients.

Published in:

Supportive Care in Cancer, 2022, v. 30, n. 11, p. 9181, doi. 10.1007/s00520-022-07343-5

By:

van Laar, Sylvia A.;
Gombert-Handoko, Kim B.;
Wassenaar, Sophie;
Kroep, Judith R.;
Guchelaar, Henk-Jan;
Zwaveling, Juliette

Publication type:

Article

Exposure to phototoxic NSAIDs and quinolones is associated with an increased risk of melanoma.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 7, p. 1437, doi. 10.1007/s00228-013-1476-x

By:

Siiskonen, Satu;
Koomen, Els;
Visser, Loes;
Herings, Ron;
Guchelaar, Henk-Jan;
Ch. Stricker, Bruno;
Nijsten, Tamar

Publication type:

Article

Dopamine agonists and ischemic complications in Parkinson's disease: a nested case-control study.

Published in:

European Journal of Clinical Pharmacology, 2012, v. 68, n. 1, p. 83, doi. 10.1007/s00228-011-1084-6

By:

Arbouw, Maurits;
Movig, Kris;
Guchelaar, Henk-Jan;
Neef, Cees;
Egberts, Toine

Publication type:

Article

Explaining variability in ciclosporin exposure in adult kidney transplant recipients.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 6, p. 579, doi. 10.1007/s00228-010-0810-9

By:

Press, Rogier;
Ploeger, Bart;
Hartigh, Jan;
Straaten, T.;
Pelt, Hans;
Danhof, Meindert;
Fijter, Hans;
Guchelaar, Henk-Jan

Publication type:

Article

Clinical and pharmacogenetic determinants for the discontinuation of non-ergoline dopamine agonists in Parkinson’s disease.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 12, p. 1245, doi. 10.1007/s00228-009-0708-6

By:

Arbouw, Maurits E. L.;
Movig, Kris L. L.;
Egberts, Toine C. G.;
Poels, Petra J. E.;
van Vugt, Jeroen P. P.;
Wessels, Judith A. M.;
van der Straaten, R. J. H. M.;
Neef, Cees;
Guchelaar, Henk-Jan

Publication type:

Article

Discontinuation of ropinirole and pramipexole in patients with Parkinson’s disease: clinical practice versus clinical trials.

Published in:

European Journal of Clinical Pharmacology, 2008, v. 64, n. 10, p. 1021, doi. 10.1007/s00228-008-0518-2

By:

Arbouw, Maurits;
Movig, Kris;
Guchelaar, Henk-Jan;
Poels, Petra;
Vugt, Jeroen;
Neef, Cees;
Egberts, Toine

Publication type:

Article

Influence of initial use of serotonergic antidepressants on antiparkinsonian drug use in levodopa-using patients.

Published in:

European Journal of Clinical Pharmacology, 2007, v. 63, n. 2, p. 181, doi. 10.1007/s00228-006-0233-9

By:

Arbouw, Maurits;
Movig, Kris;
Neef, Cees;
Guchelaar, Henk-Jan;
Egberts, Toine

Publication type:

Article

Assay performance and stability of uracil and dihydrouracil in clinical practice.

Published in:

Cancer Chemotherapy & Pharmacology, 2023, v. 91, n. 3, p. 257, doi. 10.1007/s00280-023-04518-7

By:

Knikman, Jonathan E.;
Rosing, Hilde;
Guchelaar, Henk-Jan;
Cats, Annemieke;
Beijnen, Jos H.

Publication type:

Article

Detecting DPD deficiency: when perfect is the enemy of good.

Published in:

2021

By:

Ciccolini, Joseph;
Milano, Gérard;
Guchelaar, Henk-Jan

Publication type:

Letter

Prediction of Flucytosine-Induced Thrombocytopenia Using Creatinine Clearance.

Published in:

Chemotherapy (0009-3157), 2000, v. 46, n. 5, p. 335, doi. 10.1159/000007307

By:

Vermes, Andras;
Guchelaar, Henk-Jan;
Dankert, Jacob

Publication type:

Article

Flucytosine: Correlation between Toxicity and Pharmacokinetic Parameters.

Published in:

Chemotherapy (0009-3157), 2000, v. 46, n. 2, p. 86, doi. 10.1159/000007260

By:

Vermes, Andras;
van der Sijs, Heleen;
Guchelaar, Henk-Jan

Publication type:

Article

RAINFOREST: a random forest approach to predict treatment benefit in data from (failed) clinical drug trials.

Published in:

Bioinformatics, 2020, v. 36, p. i601, doi. 10.1093/bioinformatics/btaa799

By:

Ubels, Joske;
Schaefers, Tilman;
Punt, Cornelis;
Guchelaar, Henk-Jan;
Ridder, Jeroen de

Publication type:

Article

Lapatinib for Advanced or Metastatic Breast Cancer.

Published in:

Oncologist, 2012, v. 17, n. 4, p. 536, doi. 10.1634/theoncologist.2011-0461

By:

OPDAM, FRANS L.;
GUCHELAAR, HENK-JAN;
BEIJNEN, JOS H.;
SCHELLENS, JAN H. M.

Publication type:

Article

Concordance of Predictive Markers for EGFR Inhibitors in Primary Tumors and Metastases in Colorectal Cancer: A Review.

Published in:

Oncologist, 2011, v. 16, n. 9, p. 1239, doi. 10.1634/theoncologist.2011-0024

By:

BAAS, JARA M.;
KRENS, LISANNE L.;
GUCHELAAR, HENK-JAN;
MORREAU, HANS;
GELDERBLOM, HANS

Publication type:

Article

Medication Errors: Hospital Pharmacist Perspective.

Published in:

Drugs, 2005, v. 65, n. 13, p. 1735, doi. 10.2165/00003495-200565130-00001

By:

Guchelaar, Henk-Jan;
Colen, Hadewig B. B.;
Kalmeijer, Mathijs D.;
Hudson, Patrick T. W.;
Teepe-Twiss, Irene M.

Publication type:

Article

3D Printing of Pediatric Medication: The End of Bad Tasting Oral Liquids?—A Scoping Review.

Published in:

Pharmaceutics, 2022, v. 14, n. 2, p. 416, doi. 10.3390/pharmaceutics14020416

By:

Lafeber, Iris;
Ruijgrok, Elisabeth J.;
Guchelaar, Henk-Jan;
Schimmel, Kirsten J. M.

Publication type:

Article

The Potential Application of Extracellular Vesicles from Liquid Biopsies for Determination of Pharmacogene Expression.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 2, p. 252, doi. 10.3390/ph15020252

By:

Habtemariam, Henok D.;
Guchelaar, Henk-Jan

Publication type:

Article

Genotyping for HLA Risk Alleles to Prevent Drug Hypersensitivity Reactions: Impact Analysis.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 1, p. 4, doi. 10.3390/ph15010004

By:

Manson, Lisanne E. N.;
van den Hout, Wilbert B.;
Guchelaar, Henk-Jan

Publication type:

Article

Alternative methods to a TaqMan assay to detect a tri-allelic single nucleotide polymorphism rs757210 in the HNF1β gene.

Published in:

Clinical Chemistry & Laboratory Medicine, 2012, v. 50, n. 2, p. 279, doi. 10.1515/cclm.2011.758

By:

Swen, Jesse J.;
Baak-Pablo, Renee F.;
Guchelaar, Henk-Jan;
van der Straaten, Tahar

Publication type:

Article

Translating Pharmacogenomics: Challenges on the Road to the Clinic.

Published in:

PLoS Medicine, 2007, v. 4, n. 8, p. e209, doi. 10.1371/journal.pmed.0040209

By:

Swen, Jesse J.;
Huizinga, Tom W.;
Gelderblom, Hans;
De Vries, Elisabeth G. E.;
Assendelft, Willem J. J.;
Kirchheiner, Julia;
Guchelaar, Henk-Jan

Publication type:

Article

Exposure-response analysis of endoxifen serum concentrations in early-breast cancer.

Published in:

2020

By:

Sanchez-Spitman, Anabel Beatriz;
Moes, Dirk-Jan A. R.;
Swen, Jesse J.;
Dezentjé, Vincent O.;
Lambrechts, Diether;
Neven, Patrick;
Gelderblom, Hans;
Guchelaar, Henk-Jan

Publication type:

journal article

Population pharmacokinetics of lenalidomide in multiple myeloma patients.

Published in:

2017

By:

Guglieri-López, Beatriz;
Pérez-Pitarch, Alejandro;
Moes, Dirk;
Porta-Oltra, Begoña;
Climente-Martí, Mónica;
Guchelaar, Henk;
Merino-Sanjuán, Matilde;
Guglieri-López, Beatriz;
Pérez-Pitarch, Alejandro;
Moes, Dirk Jan A R;
Porta-Oltra, Begoña;
Climente-Martí, Mónica;
Guchelaar, Henk Jan;
Merino-Sanjuán, Matilde

Publication type:

journal article

Influence of metastatic disease on the usefulness of uracil pharmacokinetics as a screening tool for DPD activity in colorectal cancer patients.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 76, n. 1, p. 47, doi. 10.1007/s00280-015-2746-3

By:

Staveren, Maurice;
Opdam, Frans;
Guchelaar, Henk-Jan;
Kuilenburg, André;
Maring, Jan;
Gelderblom, Hans

Publication type:

Article

Pharmacokinetics of orally administered uracil in healthy volunteers and in DPD-deficient patients, a possible tool for screening of DPD deficiency.

Published in:

2011

By:

van Staveren MC;
Theeuwes-Oonk B;
Guchelaar HJ;
van Kuilenburg AB;
Maring JG;
van Staveren, Maurice C;
Theeuwes-Oonk, Barbara;
Guchelaar, Henk Jan;
van Kuilenburg, André B P;
Maring, Jan Gerard

Publication type:

journal article

Marginal increase of sunitinib exposure by grapefruit juice.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 3, p. 695, doi. 10.1007/s00280-010-1367-0

By:

Erp, Nielka;
Baker, Sharyn;
Zandvliet, Anthe;
Ploeger, Bart;
Hollander, Margaret;
Chen, Zhaoyuan;
Hartigh, Jan;
König-Quartel, Jacqueline;
Guchelaar, Henk-Jan;
Gelderblom, Hans

Publication type:

Article

Is rectal administration an alternative route for imatinib?

Published in:

Cancer Chemotherapy & Pharmacology, 2007, v. 60, n. 4, p. 623, doi. 10.1007/s00280-006-0409-0

By:

Erp, Nielka;
Oostendorp, Roos;
Guchelaar, Henk-Jan;
Schellens, Jan;
Gelderblom, Hans

Publication type:

Article