Works by Guan, Xiangdong

Results: 41

Dynamic increase in myoglobin level is associated with poor prognosis in critically ill patients: a retrospective cohort study.

Published in:

Frontiers in Medicine, 2024, p. 1, doi. 10.3389/fmed.2023.1337403

By:

Yishan Liu;
Jinlong Jiang;
Hao Yuan;
Luhao Wang;
Wenliang Song;
Fei Pei;
Xiang Si;
Shumin Miao;
Minying Chen;
Bin Gu;
Xiangdong Guan;
Jianfeng Wu

Publication type:

Article

Mesenteric Lymph Duct Drainage Attenuates Lung Inflammatory Injury and Inhibits Endothelial Cell Apoptosis in Septic Rats.

Published in:

BioMed Research International, 2020, p. 1, doi. 10.1155/2020/3049302

By:

Liu, Yongjun;
Chen, Chuanxi;
Sun, Qing;
Sun, Huadong;
Liu, Ning;
Liu, Qier;
Ma, Jie;
Wang, Pingping;
Hu, Chunlin;
Wu, Jianfeng;
Ouyang, Bin;
Chen, Juan;
Chen, Minying;
Guan, Xiangdong

Publication type:

Article

Genetic correlations and causal associations between BMI, HDL-C, and postoperative infections: a two-sample Mendelian randomization study.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-95812-2

By:

Yang, Tao;
Chen, Zhe;
Cao, Daiyin;
Song, Wenliang;
Jiang, Jinlong;
Ma, Xiaoxun;
Mao, Zhi;
Guan, Xiangdong;
Wu, Jianfeng;
Shi, Rui;
Si, Xiang

Publication type:

Article

Correction to: Association between hospital and ICU structural factors and patient outcomes in China: a secondary analysis of the National Clinical Improvement System Data in 2019.

Published in:

2022

By:

Li, Zhen;
Ma, Xudong;
Gao, Sifa;
Li, Qi;
Luo, Hongbo;
Sun, Jianhua;
Du, Wei;
Su, Longxiang;
Wang, Lu;
Zhang, Qing;
Li, Zunzhu;
Zhou, Xiang;
Liu, Dawei;
China National Critical Care Quality Control Center Group;
Wang, Xue;
Guan, Xiangdong;
Kang, Yan;
Xiong, Bin;
Qin, Bingyu;
Qian, Kejian

Publication type:

corrected article

Association between hospital and ICU structural factors and patient outcomes in China: a secondary analysis of the National Clinical Improvement System Data in 2019.

Published in:

Critical Care, 2022, v. 26, n. 1, p. 1, doi. 10.1186/s13054-022-03892-7

By:

Li, Zhen;
Ma, Xudong;
Gao, Sifa;
Li, Qi;
Luo, Hongbo;
Sun, Jianhua;
Du, Wei;
Su, Longxiang;
Wang, Lu;
Zhang, Qing;
Li, Zunzhu;
Zhou, Xiang;
Liu, Dawei;
China National Critical Care Quality Control Center Group;
Wang, Xue;
Guan, Xiangdong;
Kang, Yan;
Xiong, Bin;
Qin, Bingyu;
Qian, Kejian

Publication type:

Article

Association between hospital and ICU structural factors and patient outcomes in China: a secondary analysis of the National Clinical Improvement System Data in 2019.

Published in:

2022

By:

Li, Zhen;
Ma, Xudong;
Gao, Sifa;
Li, Qi;
Luo, Hongbo;
Sun, Jianhua;
Du, Wei;
Su, Longxiang;
Wang, Lu;
Zhang, Qing;
Li, Zunzhu;
Zhou, Xiang;
Liu, Dawei;
China National Critical Care Quality Control Center Group;
Wang, Xue;
Guan, Xiangdong;
Kang, Yan;
Xiong, Bin;
Qin, Bingyu;
Qian, Kejian

Publication type:

journal article

Dynamic changes and prognosis value of plasma syndecan‐1 and different microcirculatory parameters in sepsis: A prospective observational study.

Published in:

World Journal of Surgery, 2025, v. 49, n. 2, p. 353, doi. 10.1002/wjs.12452

By:

Qian, Xiayan;
Lui, Ka Yin;
Hu, Xiaoguang;
Li, Shuhe;
Song, Xiaodong;
Lin, Changcheng;
Liang, Yujun;
Guan, Xiangdong;
Cai, Changjie

Publication type:

Article

Critical care crisis and some recommendations during the COVID-19 epidemic in China.

Published in:

2020

By:

Xie, Jianfeng;
Tong, Zhaohui;
Guan, Xiangdong;
Du, Bin;
Qiu, Haibo;
Slutsky, Arthur S.

Publication type:

journal article

Lysosome and Cytoskeleton Pathways Are Robustly Enriched in the Blood of Septic Patients: A Meta-Analysis of Transcriptomic Data.

Published in:

Mediators of Inflammation, 2015, v. 2015, p. 1, doi. 10.1155/2015/984825

By:

Ma, Jie;
Chen, Chuanxi;
Barth, Andreas S.;
Cheadle, Chris;
Guan, Xiangdong;
Gao, Li

Publication type:

Article

Systemic Corticosteroids and Mortality in Severe and Critical COVID-19 Patients in Wuhan, China.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2020, v. 105, n. 12, p. 1, doi. 10.1210/clinem/dgaa627

By:

Jianfeng Wu;
Jianqiang Huang;
Guochao Zhu;
Yihao Liu;
Han Xiao;
Qian Zhou;
Xiang Si;
Hui Yi;
Cuiping Wang;
Daya Yang;
Shuling Chen;
Xin Liu;
Zelong Liu;
Qiongya Wang;
Qingquan Lv;
Ying Huang;
Yang Yu;
Xiangdong Guan;
Yanbing Li;
Nirantharakumar, Krishnarajah

Publication type:

Article

Invasive candidiasis in intensive care units in China: a multicentre prospective observational study.

Published in:

2013

By:

Guo, Fengmei;
Yang, Yi;
Kang, Yan;
Zang, Bin;
Cui, Wei;
Qin, Bingyu;
Qin, Yingzhi;
Fang, Qiang;
Qin, Tiehe;
Jiang, Dongpo;
Li, Weiqin;
Gu, Qin;
Zhao, Hongsheng;
Liu, Dawei;
Guan, Xiangdong;
Li, Jianguo;
Ma, Xiaochun;
Yu, Kaijiang;
Chan, Dechang;
Yan, Jing

Publication type:

journal article

Invasive candidiasis in intensive care units in China: a multicentre prospective observational study.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2013, v. 68, n. 7, p. 1660

By:

Guo, Fengmei;
Yang, Yi;
Kang, Yan;
Zang, Bin;
Cui, Wei;
Qin, Bingyu;
Qin, Yingzhi;
Fang, Qiang;
Qin, Tiehe;
Jiang, Dongpo;
Li, Weiqin;
Gu, Qin;
Zhao, Hongsheng;
Liu, Dawei;
Guan, Xiangdong;
Li, Jianguo;
Ma, Xiaochun;
Yu, Kaijiang;
Chan, Dechang;
Yan, Jing

Publication type:

Article

Incidence and risk factors of Post-intensive care syndrome (PICS) in surgical ICU survivors: a prospective Chinese cohort study.

Published in:

BMC Public Health, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12889-024-20757-6

By:

Lui, Ka Yin;
Luo, Gen;
Li, Shuhe;
Song, Xiaodong;
Qian, Xiayan;
Dou, Ruoxu;
Li, Liqiong;
Guan, Xiangdong;
Cai, Changjie

Publication type:

Article

Comparison of the efficacy and safety of Landiolol and Esmolol in critically ill patients: a propensity score-matched study.

Published in:

Annals of Intensive Care, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13613-024-01418-8

By:

Si, Xiang;
Yuan, Hao;
Shi, Rui;
Song, Wenliang;
Guo, Jiayan;
Jiang, Jinlong;
Yang, Tao;
Ma, Xiaoxun;
Wang, Huiming;
Chen, Minying;
Wu, Jianfeng;
Guan, Xiangdong;
Monnet, Xavier

Publication type:

Article

Early sedation using ciprofol for intensive care unit patients requiring mechanical ventilation: a pooled post-hoc analysis of data from phase 2 and phase 3 trials.

Published in:

Annals of Intensive Care, 2024, v. 14, n. 1, p. 1, doi. 10.1186/s13613-024-01390-3

By:

Liu, Yongjun;
Zuo, Lingyun;
Li, Xiaoyun;
Nie, Yao;
Chen, Chuanxi;
Liu, Ning;
Chen, Minying;
Wu, Jianfeng;
Guan, Xiangdong

Publication type:

Article

Ferrostatin-1 improves acute sepsis-induced cardiomyopathy via inhibiting neutrophil infiltration through impaired chemokine axis.

Published in:

Frontiers in Cell & Developmental Biology, 2024, p. 1, doi. 10.3389/fcell.2024.1510232

By:

Li, Jialin;
Xiao, Fang;
Lin, Bingsen;
Huang, Zhilei;
Wu, Mingyue;
Ma, Huan;
Dou, Ruoxu;
Song, Xiaodong;
Wang, Zhongxing;
Cai, Changjie;
Guan, Xiangdong;
Xu, Jie;
Xiang, Fu-Li

Publication type:

Article

Developing an Interpretable Machine Learning Model to Predict in-Hospital Mortality in Sepsis Patients: A Retrospective Temporal Validation Study.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 3, p. 915, doi. 10.3390/jcm12030915

By:

Li, Shuhe;
Dou, Ruoxu;
Song, Xiaodong;
Lui, Ka Yin;
Xu, Jinghong;
Guo, Zilu;
Hu, Xiaoguang;
Guan, Xiangdong;
Cai, Changjie

Publication type:

Article

Identifying early blood glucose trajectories in sepsis linked to distinct long-term outcomes: a K-means clustering study with external validation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1610519

By:

Ma, Huan;
Qian, Xiayan;
Song, Xiaodong;
Jiang, Rongjie;
Li, Jialin;
Xiao, Fang;
Dou, Ruoxu;
Guan, Xiangdong;
Lui, Ka Yin;
Li, Shuhe;
Cai, Changjie

Publication type:

Article

Use of extracorporeal membrane oxygenation in adult trauma patients with refractory acute cardiopulmonary failure: guideline from the Chinese society of extracorporeal life support 2025.

Published in:

Critical Care, 2025, v. 29, n. 1, p. 1, doi. 10.1186/s13054-025-05504-6

By:

Wang, Hua;
Cen, Zhongran;
Liu, Xingxing;
Liu, Zhanguo;
Hou, Xiaotong;
Guan, Xiangdong;
Wu, Jianfeng;
Li, Yimin;
Xu, Yonghao;
Zhou, Chengbin;
Peng, Zhiyong;
Zhou, Fachun;
Sun, Tongwen;
Qin, Bingyu;
Lin, Jiandong;
Zhang, Lina;
Li, Jinghui;
Shang, You;
Liu, Songqiao;
Zeng, Zhenhua

Publication type:

Article

Performance of broad-spectrum targeted next-generation sequencing in lower respiratory tract infections in ICU patients: a prospective observational study.

Published in:

Critical Care, 2025, v. 29, n. 1, p. 1, doi. 10.1186/s13054-025-05470-z

By:

Chen, Chuanxi;
Wang, Ruizhi;
Wei, Bilin;
Chen, Yili;
Gu, Dejian;
Xu, Jiangze;
Zheng, Huifang;
Xu, Zimeng;
Ding, Linfang;
Chen, Xiaonan;
Xiao, Lihua;
Bai, Liping;
Liu, Zimeng;
Liu, Yongjun;
Chen, Minying;
Chen, Peisong;
Guan, Xiangdong;
Wu, Jianfeng

Publication type:

Article

Upregulation of the microRNA rno-miR-146b-5p may be involved in the development of intestinal injury through inhibition of Kruppel-like factor 4 in intestinal sepsis.

Published in:

Bioengineered, 2020, v. 11, n. 1, p. 1334, doi. 10.1080/21655979.2020.1851476

By:

Tong, Li;
Tang, Chaoxia;
Cai, Changjie;
Guan, Xiangdong

Publication type:

Article

The efficacy of thymosin alpha 1 for severe sepsis (ETASS): a multicenter, single-blind, randomized and controlled trial.

Published in:

Critical Care, 2013, v. 17, n. 1, p. 1, doi. 10.1186/cc11932

By:

Jianfeng Wu;
Lixin Zhou;
Jiyun Liu;
Gang Ma;
Qiuye Kou;
Zhijie He;
Juan Chen;
Bin Ou-Yang;
Minying Chen;
Yinan Li;
Xiaoqin Wu;
Baochun Gu;
Lei Chen;
Zijun Zou;
Xinhua Qiang;
Yuanyuan Chen;
Aihua Lin;
Guanrong Zhang;
Xiangdong Guan

Publication type:

Article

The efficacy of thymosin alpha 1 for severe sepsis (ETASS): a multicenter, single-blind, randomized and controlled trial.

Published in:

2013

By:

Wu, Jianfeng;
Zhou, Lixin;
Liu, Jiyun;
Ma, Gang;
Kou, Qiuye;
He, Zhijie;
Chen, Juan;
Ou-Yang, Bin;
Chen, Minying;
Li, Yinan;
Wu, Xiaoqin;
Gu, Baochun;
Chen, Lei;
Zou, Zijun;
Qiang, Xinhua;
Chen, Yuanyuan;
Lin, Aihua;
Zhang, Guanrong;
Guan, Xiangdong

Publication type:

journal article

Study Protocol of a Multicenter, Randomized, Single-Blind Trial: Efficacy and Safety of Remimazolam Tosylate for Sedation in ICU Patients.

Published in:

Advances in Therapy, 2023, v. 40, n. 5, p. 2524, doi. 10.1007/s12325-023-02456-7

By:

Liu, Ning;
Jiang, Zhiyi;
Nie, Yao;
Zuo, Lingyun;
Chen, Chuanxi;
Si, Xiang;
Liu, Qin;
Chen, Minying;
Guan, Xiangdong

Publication type:

Article

Efficacy and Safety of Ciprofol Sedation in ICU Patients with Mechanical Ventilation: A Clinical Trial Study Protocol.

Published in:

Advances in Therapy, 2021, v. 38, n. 10, p. 5412, doi. 10.1007/s12325-021-01877-6

By:

Liu, Yongjun;
Chen, Chuanxi;
Liu, Ning;
Tong, Li;
Nie, Yao;
Wu, Jianfeng;
Liu, Xiao;
Gao, Wei;
Tang, Lei;
Guan, Xiangdong

Publication type:

Article

Chinese critical care certified course in intensive care unit: a nationwide-based analysis.

Published in:

BMC Medical Education, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12909-023-04534-4

By:

Li, Li;
Xu, Qianghong;
Cai, Guolong;
Gong, Shijin;
Liu, Dawei;
Qiu, Haibo;
Yu, Kaijiang;
Chen, Dechang;
Guan, Xiangdong;
Yan, Jing

Publication type:

Article

Clinical Characteristics of Patients Who Died of Coronavirus Disease 2019 in China.

Published in:

JAMA Network Open, 2020, v. 3, n. 4, p. e205619, doi. 10.1001/jamanetworkopen.2020.5619

By:

Xie, Jianfeng;
Tong, Zhaohui;
Guan, Xiangdong;
Du, Bin;
Qiu, Haibo

Publication type:

Article

Evaluation of the Puritan Bennett™ 980 Ventilator System Safety and Performance in the Real-World Setting.

Published in:

Medical Devices: Evidence & Research, 2024, v. 17, p. 37, doi. 10.2147/MDER.S433900

By:

Roshon, Michael;
Khandhar, Paras B;
Biniwale, Manoj;
Ramanathan, Rangasamy;
Frazier, T Patrick;
Xu, Feng;
Zhang, Linlin;
Guan, Xiangdong;
Wenling, Dai;
Lambermont, Bernard

Publication type:

Article

Clinical features of 375 COVID-19 cases imported from Russia through the Suifenhe port and countermeasures.

Published in:

PLoS ONE, 2021, v. 16, n. 12, p. 1, doi. 10.1371/journal.pone.0261437

By:

Kang, Kai;
Yang, Yi;
Guan, Xiangdong;
Kang, Yan;
Zhao, Mingyan;
Yu, Jianbo;
Zeng, Xiqiu;
Xie, Fengjie;
Chen, Guolin;
Yu, Kaijiang

Publication type:

Article

Fat-Modified Enteral Formula Improves Feeding Tolerance in Critically Ill Patients: A Multicenter, Single-Blind, Randomized Controlled Trial.

Published in:

2017

By:

Qiu, Chunfang;
Chen, Chuanxi;
Zhang, Weixing;
Kou, Qiuye;
Wu, Shengnan;
Zhou, Lixin;
Liu, Jiyun;
Ma, Gang;
Chen, Juan;
Chen, Minying;
Luo, Hua;
Zhang, Xiaofei;
Lai, Jianbo;
Yu, Zhihui;
Yu, Xiaochun;
Liao, Wei;
Guan, Xiangdong;
Ouyang, Bin

Publication type:

journal article

Carbapenem is not always the best choice in the treatment of septic shock.

Published in:

European Journal of Medical Research, 2023, v. 28, n. 1, p. 1, doi. 10.1186/s40001-023-01341-x

By:

Wang, Lu;
Ma, Xudong;
Chen, Yujie;
Gao, Sifa;
He, Huaiwu;
Su, Longxiang;
Guo, Yanhong;
Shan, Guangliang;
Hu, Yaoda;
Zhou, Xiang;
Liu, Dawei;
China National Critical Care Quality Control Centre Group (China-NCCQC);
Wang, Xue;
Guan, Xiangdong;
Kang, Yan;
Xiong, Bin;
Qin, Bingyu;
Qian, Kejian;
Wang, Chunting;
Zhao, Mingyan

Publication type:

Article

Molecular mechanisms and cellular functions of liquid-liquid phase separation during antiviral immune responses.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1162211

By:

Shuai Yang;
Weishan Shen;
Jiajia Hu;
Sihui Cai;
Chenqiu Zhang;
Shouheng Jin;
Xiangdong Guan;
Jianfeng Wu;
Yaoxing Wu;
Jun Cui

Publication type:

Article

PKR inhibition mediates endotoxin tolerance in macrophages through inactivation of PI3K/AKT signaling.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 6, p. 8548, doi. 10.3892/mmr.2018.8869

By:

Xu, Hailin;
ChEN, Juan;
Si, Xiang;
ChEN, Minying;
Pei, Fei;
Qiu, Chunfang;
Wu, JianfENg;
Guan, Xiangdong

Publication type:

Article

Human trypsin inhibitor reduces the apoptosis of lipopolysaccharide‑induced human kidney‑2 cells by promoting mitochondrial fusion.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 3, p. 2899, doi. 10.3892/mmr.2017.6927

By:

NING LIU;
ZHIYI JIANG;
YONGJUN LIU;
YAO NIE;
JUAN CHEN;
BIN OUYANG;
XIANGDONG GUAN;
MINYING CHEN

Publication type:

Article

Improving Intestinal Barrier Function in Sepsis by Partially Hydrolysed Guar Gum via the Suppression of the NF-κB/MLCK Pathway.

Published in:

Molecular Biotechnology, 2025, v. 67, n. 5, p. 2035, doi. 10.1007/s12033-024-01180-z

By:

Tang, Zhaoxia;
Zhu, Yanping;
Hu, Xiaoguang;
Lui, Kayin;
Li, Shuhe;
Song, Xiaodong;
Cai, Changjie;
Guan, Xiangdong

Publication type:

Article

Autophagy Activation Induces p62-Dependent Autophagic Degradation of Dengue Virus Capsid Protein During Infection.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.889693

By:

Yaoxing Wu;
Tao Zhou;
Jiajia Hu;
Yishan Liu;
Shouheng Jin;
Jianfeng Wu;
Xiangdong Guan;
Jun Cui

Publication type:

Article

Targeting Selective Autophagy as a Therapeutic Strategy for Viral Infectious Diseases.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.889835

By:

Liu, Yishan;
Zhou, Tao;
Hu, Jiajia;
Jin, Shouheng;
Wu, Jianfeng;
Guan, Xiangdong;
Wu, Yaoxing;
Cui, Jun

Publication type:

Article

Effect of ICU quality control indicators on VAP incidence rate and mortality: a retrospective study of 1267 hospitals in China.

Published in:

Critical Care, 2022, v. 26, n. 1, p. 1, doi. 10.1186/s13054-022-04285-6

By:

Ding, Xin;
Ma, Xudong;
Gao, Sifa;
Su, Longxiang;
Shan, Guangliang;
Hu, Yaoda;
Chen, Jieqing;
Ma, Dandan;
Zhang, Feng;
Zhu, Wen;
Sun, Guoqiang;
Meng, Xiaoyang;
Ma, Lian;
Zhou, Xiang;
Liu, Dawei;
Du, Bin;
China National Critical Care Quality Control Center Group;
Wang, Xue;
Guan, Xiangdong;
Kang, Yan

Publication type:

Article

N-Acetylcysteine Inhibits Ventilation-Induced Collagen Accumulation in the Rat Lung.

Published in:

Tohoku Journal of Experimental Medicine, 2015, v. 236, n. 4, p. 255, doi. 10.1620/tjem.236.255

By:

Chuanxi Chen;
Xiangdong Guan;
Quinn, Deborah A.;
Bin Ouyang

Publication type:

Article

Effects of sedatives on diaphragm activity monitored by ultrasound: a systematic review and meta-analysis.

Published in:

BMC Anesthesiology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12871-025-03187-8

By:

Luo, Jiaren;
Wang, Luhao;
Wei, Bilin;
Huang, Zhikun;
Zheng, Huifang;
Gu, Bin;
Pei, Fei;
Chang, Zenan;
Liu, Yang;
Guan, Xiangdong;
Zhang, Xuyu;
Liu, Zimeng

Publication type:

Article

Comparison of noninvasive electrical cardiometry and transpulmonary thermodilution for cardiac output measurement in critically ill patients: a prospective observational study.

Published in:

BMC Anesthesiology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12871-025-03005-1

By:

Song, Wenliang;
Guo, Jiayan;
Cao, Daiyin;
Jiang, Jinlong;
Yang, Tao;
Ma, Xiaoxun;
Yuan, Hao;
Wu, Jianfeng;
Guan, Xiangdong;
Si, Xiang

Publication type:

Article