Works matching AU Grundberg, Elin

Results: 51

Complex trait associations in rare diseases and impacts on Mendelian variant interpretation.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52407-1

By:

Smail, Craig;
Ge, Bing;
Keever-Keigher, Marissa R.;
Schwendinger-Schreck, Carl;
Cheung, Warren A.;
Johnston, Jeffrey J.;
Barrett, Cassandra;
Feldman, Keith;
Cohen, Ana S. A.;
Farrow, Emily G.;
Thiffault, Isabelle;
Grundberg, Elin;
Pastinen, Tomi

Publication type:

Article

Impact of Prior Infection and Age on Antibody Persistence After Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccine.

Published in:

Clinical Infectious Diseases, 2022, v. 75, n. 1, p. e902, doi. 10.1093/cid/ciab850

By:

Fraley, Elizabeth;
LeMaster, Cas;
Khanal, Santosh;
Banerjee, Dithi;
Pastinen, Tomi;
Grundberg, Elin;
Selvarangan, Rangaraj;
Bradley, Todd

Publication type:

Article

Mapping cis- and trans-regulatory effects across multiple tissues in twins.

Published in:

Nature Genetics, 2012, v. 44, n. 10, p. 1084, doi. 10.1038/ng.2394

By:

Grundberg, Elin;
Small, Kerrin S;
Hedman, Åsa K;
Nica, Alexandra C;
Buil, Alfonso;
Keildson, Sarah;
Bell, Jordana T;
Yang, Tsun-Po;
Meduri, Eshwar;
Barrett, Amy;
Nisbett, James;
Sekowska, Magdalena;
Wilk, Alicja;
Shin, So-Youn;
Glass, Daniel;
Travers, Mary;
Min, Josine L;
Ring, Sue;
Ho, Karen;
Thorleifsson, Gudmar

Publication type:

Article

Corrigendum: Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes.

Published in:

2011

By:

Small, Kerrin S;
Hedman, Åsa K;
Grundberg, Elin;
Nica, Alexandra C;
Thorleifsson, Gudmar;
Kong, Augustine;
Thorsteindottir, Unnur;
Shin, So-Youn;
Richards, Hannah B;
Soranzo, Nicole;
Ahmadi, Kourosh R;
Lindgren, Cecilia M;
Stefansson, Kari;
Dermitzakis, Emmanouil T;
Deloukas, Panos;
Spector, Timothy D;
McCarthy, Mark I

Publication type:

Correction Notice

Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes.

Published in:

Nature Genetics, 2011, v. 43, n. 6, p. 561, doi. 10.1038/ng.833

By:

Small, Kerrin S.;
Hedman, Åsa K.;
Grundberg, Elin;
Nica, Alexandra C.;
Thorleifsson, Gudmar;
Kong, Augustine;
Thorsteindottir, Unnur;
So-Youn Shin;
Richards, Hannah B.;
Soranzo, Nicole;
Ahmadi, Kourosh R.;
Lindgren, Cecilia M.;
Stefansson, Kari;
Dermitzakis, Emmanouil T.;
Deloukas, Panos;
Spector, Timothy D.;
McCarthy, Mark I.

Publication type:

Article

Global patterns of cis variation in human cells revealed by high-density allelic expression analysis.

Published in:

Nature Genetics, 2009, v. 41, n. 11, p. 1216, doi. 10.1038/ng.473

By:

Ge, Bing;
Pokholok, Dmitry K.;
Kwan, Tony;
Grundberg, Elin;
Morcos, Lisanne;
Verlaan, Dominique J.;
Le, Jennie;
Koka, Vonda;
Lam, Kevin C. L.;
Gagné, Vincent;
Dias, Joana;
Hoberman, Rose;
Montpetit, Alexandre;
Joly, Marie-Michele;
Harvey, Edward J.;
Sinnett, Daniel;
Beaulieu, Patrick;
Hamon, Robert;
Graziani, Alexandru;
Dewar, Ken

Publication type:

Article

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.

Published in:

Nature Genetics, 2009, v. 41, n. 11, p. 1199, doi. 10.1038/ng.446

By:

Rivadeneira, Fernando;
Styrkársdottir, Unnur;
Estrada, Karol;
Halldórsson, Bjarni V.;
Yi-Hsiang Hsu;
Richards, J. Brent;
Zillikens, M. Carola;
Kavvoura, Fotini K.;
Amin, Najaf;
Aulchenko, Yurii S.;
Cupples, L. Adrienne;
Deloukas, Panagiotis;
Demissie, Serkalem;
Grundberg, Elin;
Hofman, Albert;
Kong, Augustine;
Karasik, David;
van Meurs, Joyce B.;
Oostra, Ben;
Pastinen, Tomi

Publication type:

Article

DNA Methylation at ABCG1 and Long-term Changes in Adiposity and Fat Distribution in Response to Dietary Interventions: The POUNDS Lost Trial.

Published in:

Diabetes Care, 2023, v. 46, n. 12, p. 2201, doi. 10.2337/dc23-0748

By:

Li, Xiang;
Shao, Xiaojian;
Kou, Minghao;
Wang, Xuan;
Ma, Hao;
Grundberg, Elin;
Bazzano, Lydia A.;
Smith, Steven R.;
Bray, George A.;
Sacks, Frank M.;
Qi, Lu

Publication type:

Article

Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment.

Published in:

PLoS Genetics, 2014, v. 10, n. 6, p. 1, doi. 10.1371/journal.pgen.1004423

By:

Kemp, John P.;
Medina-Gomez, Carolina;
Estrada, Karol;
St Pourcain, Beate;
Heppe, Denise H. M.;
Warrington, Nicole M.;
Oei, Ling;
Ring, Susan M.;
Kruithof, Claudia J.;
Timpson, Nicholas J.;
Wolber, Lisa E.;
Reppe, Sjur;
Gautvik, Kaare;
Grundberg, Elin;
Ge, Bing;
van der Eerden, Bram;
van de Peppel, Jeroen;
Hibbs, Matthew A.;
Ackert-Bicknell, Cheryl L.;
Choi, Kwangbom

Publication type:

Article

Genetic Determinants of Trabecular and Cortical Volumetric Bone Mineral Densities and Bone Microstructure.

Published in:

PLoS Genetics, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.pgen.1003247

By:

Paternoster, Lavinia;
Lorentzon, Mattias;
Lehtimäki, Terho;
Eriksson, Joel;
Kähönen, Mika;
Raitakari, Olli;
Laaksonen, Marika;
Sievänen, Harri;
Viikari, Jorma;
Lyytikäinen, Leo-Pekka;
Mellström, Dan;
Karlsson, Magnus;
Ljunggren, Östen;
Grundberg, Elin;
Kemp, John P.;
Sayers, Adrian;
Nethander, Maria;
Evans, David M.;
Vandenput, Liesbeth;
Tobias, Jon H.

Publication type:

Article

Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population.

Published in:

PLoS Genetics, 2012, v. 8, n. 4, p. 1, doi. 10.1371/journal.pgen.1002629

By:

Bell, Jordana T.;
Pei-Chien Tsai;
Tsun-Po Yang;
Pidsley, Ruth;
Nisbet, James;
Glass, Daniel;
Mangino, Massimo;
Guangju Zhai;
Feng Zhang;
Valdes, Ana;
So-Youn Shin;
Dempster, Emma L.;
Murray, Robin M.;
Grundberg, Elin;
Hedman, Asa K.;
Nica, Alexandra;
Small, Kerrin S.;
Dermitzakis, Emmanouil T.;
McCarthy, Mark I.;
Mill, Jonathan

Publication type:

Article

Eight Common Genetic Variants Associated with Serum DHEAS Levels Suggest a Key Role in Ageing Mechanisms.

Published in:

PLoS Genetics, 2011, v. 7, n. 4, p. 1, doi. 10.1371/journal.pgen.1002025

By:

Guangju Zhai;
Teumer, Alexander;
Stolk, Lisette;
Perry, John R. B.;
Vandenput, Liesbeth;
Coviello, Andrea D.;
Koster, Annemarie;
Bell, Jordana T.;
Bhasin, Shalender;
Eriksson, Joel;
Eriksson, Anna;
Ernst, Florian;
Ferrucci, Luigi;
Frayling, Timothy M.;
Glass, Daniel;
Grundberg, Elin;
Haring, Robin;
Hedman, Asa K.;
Hofman, Albert;
Kiel, Douglas P.

Publication type:

Article

The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study.

Published in:

PLoS Genetics, 2011, v. 7, n. 2, p. 1, doi. 10.1371/journal.pgen.1002003

By:

Nica, Alexandra C.;
Parts, Leopold;
Glass, Daniel;
Nisbet, James;
Barrett, Amy;
Sekowska, Magdalena;
Travers, Mary;
Potter, Simon;
Grundberg, Elin;
Small, Kerrin;
Hedman, Asa K.;
Bataille, Veronique;
Bell, Jordana Tzenova;
Surdulescu, Gabriela;
Dimas, Antigone S.;
Ingle, Catherine;
Nestle, Frank O.;
di Meglio, Paola;
Min, Josine L.;
Wilk, Alicja

Publication type:

Article

Global Analysis of the Impact of Environmental Perturbation on cis-Regulation of Gene Expression.

Published in:

PLoS Genetics, 2011, v. 7, n. 1, p. 1, doi. 10.1371/journal.pgen.1001279

By:

Grundberg, Elin;
Adoue, Veronique;
Kwan, Tony;
Bing Ge;
Qing Ling Duan;
Lam, Kevin C. L.;
Koka, Vonda;
Kindmark, Andreas;
Weiss, Scott T.;
Tantisira, Kelan;
Mallmin, Hans;
Raby, Benjamin A.;
Nilsson, Olle;
Pastinen, Tomi

Publication type:

Article

An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits.

Published in:

PLoS Genetics, 2010, v. 6, n. 6, p. 1, doi. 10.1371/journal.pgen.1000977

By:

Yi-Hsiang Hsu;
Zillikens, M. Carola;
Wilson, Scott G.;
Farber, Charles R.;
Demissie, Serkalem;
Soranzo, Nicole;
Bianchi, Estelle N.;
Grundberg, Elin;
Liming Liang;
Richards, J. Brent;
Estrada, Karol;
Yanhua Zhou;
van Nas, Atila;
Moffatt, Miriam F.;
Guangju Zhai;
Hofman, Albert;
van Meurs, Joyce B.;
Pols, Huibert A. P.;
Price, Roger I.;
Nilsson, Olle

Publication type:

Article

A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels.

Published in:

PLoS Genetics, 2009, v. 5, n. 12, p. 1, doi. 10.1371/journal.pgen.1000768

By:

Richards, J. Brent;
Waterworth, Dawn;
O'Rahilly, Stephen;
Hivert, Marie-France;
Loos, Ruth J. F.;
Perry, John R. B.;
Tanaka, Toshiko;
Timpson, Nicholas John;
Semple, Robert K.;
Soranzo, Nicole;
Kijoung Song;
Rocha, Nuno;
Grundberg, Elin;
Dupuis, Josée;
Florez, Jose C.;
Langenberg, Claudia;
Prokopenko, Inga;
Saxena, Richa;
Sladek, Robert;
Aulchenko, Yurii

Publication type:

Article

Tissue Effect on Genetic Control of Transcript Isoform Variation.

Published in:

PLoS Genetics, 2009, v. 5, n. 8, p. 1, doi. 10.1371/journal.pgen.1000608

By:

Kwan, Tony;
Grundberg, Elin;
Koka, Vonda;
Bing Ge;
Lam, Kevin C. L.;
Dias, Christel;
Kindmark, Andreas;
Mallmin, Hans;
Ljunggren, Östen;
Rivadeneira, Fernando;
Estrada, Karol;
van Meurs, Joyce B.;
Uitterlinden, Andre;
Karlsson, Magnus;
Ohlsson, Claes;
Mellström, Dan;
Nilsson, Olle;
Pastinen, Tomi;
Majewski, Jacek

Publication type:

Article

Large-scale analysis of circulating glutamate and adipose gene expression in relation to abdominal obesity.

Published in:

Amino Acids, 2022, v. 54, n. 9, p. 1287, doi. 10.1007/s00726-022-03181-1

By:

Maltais-Payette, Ina;
Vijay, Jinchu;
Simon, Marie-Michelle;
Corbeil, Jacques;
Brière, Francis;
Grundberg, Elin;
Tchernof, André

Publication type:

Article

A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.

Published in:

Human Molecular Genetics, 2008, v. 17, n. 18, p. 2868, doi. 10.1093/hmg/ddn184

By:

Sigurdsson, Snaevar;
Nordmark, Gunnel;
Garnier, Sophie;
Grundberg, Elin;
Kwan, Tony;
Nilsson, Olof;
Eloranta, Maija-Leena;
Gunnarsson, Iva;
Svenungsson, Elisabet;
Sturfelt, Gunnar;
Bengtsson, Anders A.;
Jönsen, Andreas;
Truedsson, Lennart;
Rantapää-Dahlqvist, Solbritt;
Eriksson, Catharina;
Alm, Gunnar;
Göring, Harald H.H.;
Pastinen, Tomi;
Syvänen, Ann-Christine;
Rönnblom, Lars

Publication type:

Article

Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers.

Published in:

Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01077-z

By:

Christiansen, Colette;
Tomlinson, Max;
Eliot, Melissa;
Nilsson, Emma;
Costeira, Ricardo;
Xia, Yujing;
Villicaña, Sergio;
Mompeo, Olatz;
Wells, Philippa;
Castillo-Fernandez, Juan;
Potier, Louis;
Vohl, Marie-Claude;
Tchernof, Andre;
Moustafa, Julia El-Sayed;
Menni, Cristina;
Steves, Claire J.;
Kelsey, Karl;
Ling, Charlotte;
Grundberg, Elin;
Small, Kerrin S.

Publication type:

Article

Vitamin D Receptor 3' Haplotypes Are Unequally Expressed in Primary Human Bone Cells and Associated With Increased Fracture Risk: The MrOS Study in Sweden and Hong Kong.

Published in:

Journal of Bone & Mineral Research, 2007, v. 22, n. 6, p. 832, doi. 10.1359/JBMR.070317

By:

Grundberg, Elin;
M. C.^ Lau, Edith;
Pastinen, Tomi;
Kindmark, Andreas;
Nilsson, Olof;
Ljunggren, Östen;
Mellstrom, Dan;
Orwoll, Eric;
Redlund-Johnell, Inga;
Holmberg, Anna;
Gurd, Scott;
Ping Chung Leung;
Kwok, Timothy;
Ohlsson, Claes;
Mallmin, Hans;
Brändstrom, Helena

Publication type:

Article

The Impact of Estradiol on Bone Mineral Density Is Modulated by the Specific Estrogen Receptor-α Cofactor Retinoblastoma-Interacting Zinc Finger Protein-1 Insertion/Deletion Polymorphism.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2007, v. 92, n. 6, p. 2300, doi. 10.1210/jc.2006-1572

By:

Grundberg, Elin;
Åkesson, Kristina;
Kindmark, Andreas;
Gerdhem, Paul;
Holmberg, Anna;
Mellström, Dan;
Ljunggren, Östen;
Orwoll, Eric;
Mallmin, Hans;
Ohlsson, Claes;
Brändström, Helena

Publication type:

Article

Extravillous trophoblast cell lineage development is associated with active remodeling of the chromatin landscape.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40424-5

By:

Varberg, Kaela M.;
Dominguez, Esteban M.;
Koseva, Boryana;
Varberg, Joseph M.;
McNally, Ross P.;
Moreno-Irusta, Ayelen;
Wesley, Emily R.;
Iqbal, Khursheed;
Cheung, Warren A.;
Schwendinger-Schreck, Carl;
Smail, Craig;
Okae, Hiroaki;
Arima, Takahiro;
Lydic, Michael;
Holoch, Kristin;
Marsh, Courtney;
Soares, Michael J.;
Grundberg, Elin

Publication type:

Article

Spectrum of mutations in MMACHC, allelic expression, and evidence for genotype-phenotype correlations.

Published in:

Human Mutation, 2009, v. 30, n. 7, p. 1072, doi. 10.1002/humu.21001

By:

Lerner-Ellis, Jordan P.;
Anastasio, Natascia;
Liu, Junhui;
Coelho, David;
Suormala, Terttu;
Stucki, Martin;
Loewy, Amanda D.;
Gurd, Scott;
Grundberg, Elin;
Morel, Chantal F.;
Watkins, David;
Baumgartner, Matthias R.;
Pastinen, Tomi;
Rosenblatt, David S.;
Fowler, Brian

Publication type:

Article

Dominant gut Prevotella copri in gastrectomised non-obese diabetic Goto–Kakizaki rats improves glucose homeostasis through enhanced FXR signalling.

Published in:

Diabetologia, 2020, v. 63, n. 6, p. 1223, doi. 10.1007/s00125-020-05122-7

By:

Péan, Noémie;
Le Lay, Aurelie;
Brial, Francois;
Wasserscheid, Jessica;
Rouch, Claude;
Vincent, Mylène;
Myridakis, Antonis;
Hedjazi, Lyamine;
Dumas, Marc-Emmanuel;
Grundberg, Elin;
Lathrop, Mark;
Magnan, Christophe;
Dewar, Ken;
Gauguier, Dominique

Publication type:

Article

Genomic insights into pediatric intestinal inflammatory and eosinophilic disorders using single-cell RNA-sequencing.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1420208

By:

Keever-Keigher, Marissa R.;
Harvey, Lisa;
Williams, Veronica;
Vyhlidal, Carrie A.;
Ahmed, Atif A.;
Johnston, Jeffery J.;
Louiselle, Daniel A.;
Grundberg, Elin;
Pastinen, Tomi;
Friesen, Craig A.;
Chevalier, Rachel;
Smail, Craig;
Shakhnovich, Valentina

Publication type:

Article

Erratum: Whole-genome sequence-based analysis of thyroid function.

Published in:

Nature Communications, 2015, v. 6, n. 5, p. 7172, doi. 10.1038/ncomms8172

By:

Taylor, Peter N.;
Porcu, Eleonora;
Chew, Shelby;
Campbell, Purdey J.;
Traglia, Michela;
Brown, Suzanne J.;
Mullin, Benjamin H.;
Shihab, Hashem A.;
Min, Josine;
Walter, Klaudia;
Memari, Yasin;
Huang, Jie;
Barnes, Michael R.;
Beilby, John P.;
Charoen, Pimphen;
Danecek, Petr;
Dudbridge, Frank;
Forgetta, Vincenzo;
Greenwood, Celia;
Grundberg, Elin

Publication type:

Article

Whole-genome sequence-based analysis of thyroid function.

Published in:

Nature Communications, 2015, v. 6, n. 3, p. 5681, doi. 10.1038/ncomms6681

By:

Taylor, Peter N.;
Porcu, Eleonora;
Chew, Shelby;
Campbell, Purdey J.;
Traglia, Michela;
Brown, Suzanne J.;
Mullin, Benjamin H.;
Shihab, Hashem A.;
Min, Josine;
Walter, Klaudia;
Memari, Yasin;
Huang, Jie;
Barnes, Michael R.;
Beilby, John P.;
Charoen, Pimphen;
Danecek, Petr;
Dudbridge, Frank;
Forgetta, Vincenzo;
Greenwood, Celia;
Grundberg, Elin

Publication type:

Article

Customized MethylC-Capture Sequencing to Evaluate Variation in the Human Sperm DNA Methylome Representative of Altered Folate Metabolism.

Published in:

Environmental Health Perspectives, 2019, v. 127, n. 8, p. 1, doi. 10.1289/EHP4812

By:

Chan, Donovan;
Xiaojian Shao;
Dumargne, Marie-Charlotte;
Aarabi, Mahmoud;
Simon, Marie-Michelle;
Kwan, Tony;
Bailey, Janice L.;
Robaire, Bernard;
Kimmins, Sarah;
San Gabriel, Maria C.;
Zini, Armand;
Librach, Clifford;
Moskovtsev, Sergey;
Grundberg, Elin;
Bourque, Guillaume;
Pastinen, Tomi;
Trasler, Jacquetta M.

Publication type:

Article

Genetic variation in the human vitamin D receptor is associated with muscle strength, fat mass and body weight in Swedish women.

Published in:

European Journal of Endocrinology, 2004, v. 150, n. 3, p. 0323

By:

Elin Grundberg;
Helena Brandstrom;
Eva L Ribom;
Osten Ljunggren;
Hans Mallmin;
Andreas Kindmark

Publication type:

Article

A genome-wide approach to identifying novel-imprinted genes.

Published in:

Human Genetics, 2008, v. 122, n. 6, p. 625, doi. 10.1007/s00439-007-0440-1

By:

Pollard, Katherine;
Serre, David;
Xu Wang;
Heng Tao;
Grundberg, Elin;
Hudson, Thomas;
Clark, Andrew;
Frazer, Kelly

Publication type:

Article

IL6 and IL1B Polymorphisms are Associated With Fat Mass in Older Men: The MrOS Study Sweden.

Published in:

Obesity (19307381), 2008, v. 16, n. 3, p. 710, doi. 10.1038/oby.2007.95

By:

Strandberg, Louise;
Mellström, Dan;
Ljunggren, Östen;
Grundberg, Elin;
Karlsson, Magnus K.;
Holmberg, Anna H.;
Orwoll, Eric S.;
Eriksson, Anna L.;
Svedberg, Johan;
Bengtsson, Magnus;
Ohlsson, Claes;
Jansson, John-Olov

Publication type:

Article

Black community member perceptions and ethics recommendations on epigenomic research.

Published in:

Clinical Epigenetics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13148-025-01840-0

By:

Berrios, Courtney;
Basey, Tammy;
Bradley-Ewing, Andrea;
Daniels-Young, Stacey;
Lewis, Daysha;
Feldman, Keith;
Moffatt, Mary E.;
Pastinen, Tomi;
Grundberg, Elin

Publication type:

Article

Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation.

Published in:

Genome Biology, 2015, v. 16, p. 1, doi. 10.1186/s13059-015-0856-1

By:

Busche, Stephan;
Xiaojian Shao;
Caron, Maxime;
Kwan, Tony;
Allum, Fiona;
Cheung, Warren A.;
Bing Ge;
Westfall, Susan;
Simon, Marie-Michelle;
Barrett, Amy;
Bell, Jordana T.;
McCarthy, Mark I.;
Deloukas, Panos;
Blanchette, Mathieu;
Bourque, Guillaume;
Spector, Timothy D.;
Lathrop, Mark;
Pastinen, Tomi;
Grundberg, Elin

Publication type:

Article

Gene expression changes with age in skin, adipose tissue, blood and brain.

Published in:

Genome Biology, 2013, v. 14, n. 7, p. R75, doi. 10.1186/gb-2013-14-7-r75

By:

Glass, Daniel;
Viñuela, Ana;
Davies, Matthew N;
Ramasamy, Adaikalavan;
Parts, Leopold;
Knowles, David;
Brown, Andrew A;
Hedman, Åsa K;
Small, Kerrin S;
Buil, Alfonso;
Grundberg, Elin;
Nica, Alexandra C;
Nestle, Frank O;
Ryten, Mina;
the UK Brain Expression consortium;
the MuTHER consortium;
Durbin, Richard;
McCarthy, Mark I;
Deloukas, Panagiotis;
Dermitzakis, Emmanouil T

Publication type:

Article

Methylation patterns of the nasal epigenome of hospitalized SARS-CoV-2 positive patients reveal insights into molecular mechanisms of COVID-19.

Published in:

BMC Medical Genomics, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s12920-025-02125-4

By:

Spector, Benjamin L;
Koseva, Boryana;
McLennan, Rebecca;
Banerjee, Dithi;
Lankachandra, Kamani;
Bradley, Todd;
Selvarangan, Rangaraj;
Grundberg, Elin

Publication type:

Article

Rare and Common Variants in GALNT3 May Affect Bone Mass Independently of Phosphate Metabolism.

Published in:

Journal of Bone & Mineral Research, 2023, v. 38, n. 5, p. 678, doi. 10.1002/jbmr.4795

By:

Hassan, Neelam;
Gregson, Celia L.;
Tang, Haotian;
van der Kamp, Marc;
Leo, Paul;
McInerney‐Leo, Aideen M.;
Zheng, Jie;
Brandi, Maria Luisa;
Tang, Jonathan C. Y.;
Fraser, William;
Stone, Michael D.;
Grundberg, Elin;
Brown, Matthew A.;
Duncan, Emma L.;
Tobias, Jonathan H.

Publication type:

Article

Common Sequence Variation in FLNB Regulates Bone Structure in Women in the General Population and FLNB mRNA Express in Osteoblasts In Vitro.

Published in:

Journal of Bone & Mineral Research, 2009, v. 24, n. 12, p. 1989, doi. 10.1359/JBMR.090530

By:

Wilson, Scott G.;
Jones, Michelle R.;
Mullin, Ben H.;
Dick, Ian M.;
Richards, J. Brent;
Pastinen, Tomi M.;
Grundberg, Elin;
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Surdulescu, Gabriela L.;
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Elliott, Katherine S.;
Cervino, Alessandra C. L.;
Spector, Timothy D.;
Prince, Richard L.

Publication type:

Article

Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity.

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Diabetes, 2014, v. 63, n. 3, p. 1154, doi. 10.2337/db13-1301

By:

Keildson, Sarah;
Fadista, Joao;
Ladenvall, Claes;
Hedman, Åsa K.;
Elgzyri, Targ;
Small, Kerrin S.;
Grundberg, Elin;
Nica, Alexandra C.;
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Richards, J. Brent;
Barrett, Amy;
Nisbet, James;
Hou-Feng Zheng;
Rönn, Tina;
Ström, Kristoffer;
Eriksson, Karl-Fredrik;
Prokopenko, Inga;
Spector, Timothy D.;
Dermitzakis, Emmanouil T.;
Deloukas, Panos

Publication type:

Article

Humoral immune responses during SARS-CoV-2 mRNA vaccine administration in seropositive and seronegative individuals.

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2021

By:

Fraley, Elizabeth;
LeMaster, Cas;
Geanes, Eric;
Banerjee, Dithi;
Khanal, Santosh;
Grundberg, Elin;
Selvarangan, Rangaraj;
Bradley, Todd

Publication type:

journal article

The Presence of Methylation Quantitative Trait Loci Indicates a Direct Genetic Influence on the Level of DNA Methylation in Adipose Tissue.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0055923

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Drong, Alexander W.;
Nicholson, George;
Hedman, Åsa K.;
Meduri, Eshwar;
Grundberg, Elin;
Small, Kerrin S.;
Shin, So-Youn;
Bell, Jordana T.;
Karpe, Fredrik;
Soranzo, Nicole;
Spector, Tim D.;
McCarthy, Mark I.;
Deloukas, Panos;
Rantalainen, Mattias;
Lindgren, Cecilia M.

Publication type:

Article

A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targeted Approach of the Infinium HumanMethylation450 BeadChip® for Methylome Profiling.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0050233

By:

Clark, Christine;
Palta, Priit;
Joyce, Christopher J.;
Scott, Carol;
Grundberg, Elin;
Deloukas, Panos;
Palotie, Aarno;
Coffey, Alison J.

Publication type:

Article

Human metabolic individuality in biomedical and pharmaceutical research.

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Nature, 2011, v. 477, n. 7362, p. 54, doi. 10.1038/nature10354

By:

Suhre, Karsten;
Shin, So-Youn;
Petersen, Ann-Kristin;
Mohney, Robert P.;
Meredith, David;
Wägele, Brigitte;
Altmaier, Elisabeth;
CARDIoGRAM;
Deloukas, Panos;
Erdmann, Jeanette;
Grundberg, Elin;
Hammond, Christopher J.;
de Angelis, Martin Hrabé;
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Köttgen, Anna;
Kronenberg, Florian;
Mangino, Massimo;
Meisinger, Christa;
Meitinger, Thomas;
Mewes, Hans-Werner

Publication type:

Article

Leveraging osteoclast genetic regulatory data to identify genes with a role in osteoarthritis.

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Genetics, 2023, v. 225, n. 2, p. 1, doi. 10.1093/genetics/iyad150

By:

Mullin, Benjamin H.;
Kun Zhu;
Brown, Suzanne J.;
Mullin, Shelby;
Dudbridge, Frank;
Pavlos, Nathan J.;
Richards, J. Brent;
Grundberg, Elin;
Bell, Jordana T.;
Zeggini, Eleftheria;
Walsh, John P.;
Jiake Xu;
Wilson, Scott G.

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Article

Cross-reactive antibodies elicited to conserved epitopes on SARS-CoV-2 spike protein after infection and vaccination.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-10230-y

By:

Geanes, Eric S.;
LeMaster, Cas;
Fraley, Elizabeth R.;
Khanal, Santosh;
McLennan, Rebecca;
Grundberg, Elin;
Selvarangan, Rangaraj;
Bradley, Todd

Publication type:

Article

Cross-reactive antibodies elicited to conserved epitopes on SARS-CoV-2 spike protein after infection and vaccination.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-10230-y

By:

Geanes, Eric S.;
LeMaster, Cas;
Fraley, Elizabeth R.;
Khanal, Santosh;
McLennan, Rebecca;
Grundberg, Elin;
Selvarangan, Rangaraj;
Bradley, Todd

Publication type:

Article

Immune cell residency in the nasal mucosa may partially explain respiratory disease severity across the age range.

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Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95532-3

By:

Winkley, Konner;
Banerjee, Dithi;
Bradley, Todd;
Koseva, Boryana;
Cheung, Warren A.;
Selvarangan, Rangaraj;
Pastinen, Tomi;
Grundberg, Elin

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Article

An epigenome-wide association study of total serum immunoglobulin E concentration.

Published in:

Nature, 2015, v. 520, n. 7549, p. 670, doi. 10.1038/nature14125

By:

Liang, Liming;
Willis-Owen, Saffron A. G.;
Laprise, Catherine;
Wong, Kenny C. C.;
Davies, Gwyneth A.;
Hudson, Thomas J.;
Binia, Aristea;
Hopkin, Julian M.;
Yang, Ivana V.;
Grundberg, Elin;
Busche, Stephan;
Hudson, Marie;
Rönnblom, Lars;
Pastinen, Tomi M.;
Schwartz, David A.;
Lathrop, G. Mark;
Moffatt, Miriam F.;
Cookson, William O. C. M.

Publication type:

Article

Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-09184-z

By:

Allum, Fiona;
Hedman, Åsa K.;
Shao, Xiaojian;
Cheung, Warren A.;
Vijay, Jinchu;
Guénard, Frédéric;
Kwan, Tony;
Simon, Marie-Michelle;
Ge, Bing;
Moura, Cristiano;
Boulier, Elodie;
Rönnblom, Lars;
Bernatsky, Sasha;
Lathrop, Mark;
McCarthy, Mark I.;
Deloukas, Panos;
Tchernof, André;
Pastinen, Tomi;
Vohl, Marie-Claude;
Grundberg, Elin

Publication type:

Article

Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation.

Published in:

Epigenetics, 2014, v. 9, n. 10, p. 1382, doi. 10.4161/15592294.2014.969637

By:

Tsaprouni, Loukia G;
Yang, Tsun-Po;
Bell, Jordana;
Dick, Katherine J;
Kanoni, Stavroula;
Nisbet, James;
Viñuela, Ana;
Grundberg, Elin;
Nelson, Christopher P;
Meduri, Eshwar;
Buil, Alfonso;
Cambien, Francois;
Hengstenberg, Christian;
Erdmann, Jeanette;
Schunkert, Heribert;
Goodall, Alison H;
Ouwehand, Willem H;
Dermitzakis, Emmanouil;
Spector, Tim D;
Samani, Nilesh J

Publication type:

Article