Works by Gruber, Karl

Results: 152
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    A Biocatalytic Henry Reaction—The Hydroxynitrile Lyase from Hevea brasiliensis Also Catalyzes Nitroaldol ReactionsWe thank Prof. Bernard Golding, University of Newcastle, for his fruitful contributions to this project. The Österreichische Forschungsförderungsgesellschaft (FFG), the Province of Styria and the Styrian Business Promotion Agency (SFG), and the city of Graz—within the framework of the Kplus programme—are acknowledged for financial support.

    Published in:
    Angewandte Chemie International Edition, 2006, v. 45, n. 21, p. 3454, doi. 10.1002/anie.200504230
    By:
    • Thomas Purkarthofer;
    • Karl Gruber;
    • Mandana Gruber-Khadjawi;
    • Kerstin Waich;
    • Wolfgang Skranc;
    • Daniel Mink;
    • Herfried Griengl
    Publication type:
    Article
    16

    Vitamin B12: A Methyl Group without a Job?We thank K.-H. Ongania for measuring FAB mass spectra. We are grateful to Hoffmann-LaRoche for a gift of vitamin B12. The project was supported by grants from the European Commission (Proj. No. HPRN-CT-2002-00195), the Austrian National Science Foundation (FWF, projects P-13595 and P-17132). X-ray diffraction data were collected at the EMBL beamline BW7b at DESY in Hamburg (Germany).

    Published in:
    Angewandte Chemie International Edition, 2006, v. 45, n. 6, p. 989, doi. 10.1002/anie.200502638
    By:
    • Philip Butler;
    • Marc-Olivier Ebert;
    • Andrzej Lyskowski;
    • Karl Gruber;
    • Christoph Kratky;
    • Bernhard Kräutler
    Publication type:
    Article
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    Carving the Active Site of Almond R-HNL for Increased EnantioselectivityThis research was supported by DSM, the FFG, the province of Styria, the SFG, and the city of Graz. We thank H. Mandl from the Research Centre Applied Biocatalysis, I. Wirth and O. Maurer from DSM for excellent technical support, and K. Faber, C. Kratky, and W. Kroutil for valuable comments on the manuscript, and P. Naggl for the color artwork.

    Published in:
    Angewandte Chemie International Edition, 2005, v. 44, n. 30, p. 4700, doi. 10.1002/anie.200500435
    By:
    • Roland Weis;
    • Richard Gaisberger;
    • Wolfgang Skranc;
    • Karl Gruber;
    • Anton Glieder
    Publication type:
    Article
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    B12-retro-Riboswitches: Constitutional Switching of B12 Coenzymes Induced by NucleotidesWe would like to thank Prof. K.-H. Ongania for mass spectrometric analyses, Mag. Tea Pavkov for assistance in X-ray data collection, Dr. M. Fasching, Prof. R. Micura, and Dr. C. Hbartner for helpful discussions, and F. Hoffmann-La Roche & Co., Basel, for a generous gift of vitamin B12. We are also grateful to the Austrian National Science Foundation (FWF, project P13595), and the European Union (project EU-HPRN-CT-2002-00195) for support of our work.

    Published in:
    Angewandte Chemie International Edition, 2005, v. 44, n. 15, p. 2284
    By:
    • Sigrid Gschsser;
    • Karl Gruber;
    • Christoph Kratky;
    • Christian Eichmller;
    • Bernhard Krutler
    Publication type:
    Article
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    Structural Studies of an Anti-Inflammatory Lectin from <i>Canavalia boliviana</i> Seeds in Complex with Dimannosides.

    Published in:
    PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0097015
    By:
    • Bezerra, Gustavo Arruda;
    • Viertlmayr, Roland;
    • Moura, Tales Rocha;
    • Delatorre, Plínio;
    • Rocha, Bruno Anderson Matias;
    • do Nascimento, Kyria Santiago;
    • Figueiredo, Jozi Godoy;
    • Bezerra, Ingrid Gonçalves;
    • Teixeira, Cicero Silvano;
    • Simões, Rafael Conceição;
    • Nagano, Celso Shiniti;
    • de Alencar, Nylane Maria Nunes;
    • Gruber, Karl;
    • Cavada, Benildo Sousa
    Publication type:
    Article
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    Structures of Human DPP7 Reveal the Molecular Basis of Specific Inhibition and the Architectural Diversity of Proline-Specific Peptidases.

    Published in:
    PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043019
    By:
    • Bezerra, Gustavo Arruda;
    • Dobrovetsky, Elena;
    • Dong, Aiping;
    • Seitova, Almagul;
    • Crombett, Lissete;
    • Shewchuk, Lisa M.;
    • Hassell, Annie M.;
    • Sweitzer, Sharon M.;
    • Sweitzer, Thomas D.;
    • Mcdevitt, Patrick J.;
    • Johanson, Kyung O.;
    • Kennedy-Wilson, Karen M.;
    • Cossar, Doug;
    • Bochkarev, Alexey;
    • Gruber, Karl;
    • Dhe-Paganon, Sirano;
    • Van Veen, Hendrik W.
    Publication type:
    Article
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    Disruption of the methyltransferase-like 23 gene METTL23 causes mild autosomal recessive intellectual disability.

    Published in:
    Human Molecular Genetics, 2014, v. 23, n. 15, p. 4015, doi. 10.1093/hmg/ddu115
    By:
    • Bernkopf, Marie;
    • Webersinke, Gerald;
    • Tongsook, Chanakan;
    • Koyani, Chintan N.;
    • Rafiq, Muhammad A.;
    • Ayaz, Muhammad;
    • Müller, Doris;
    • Enzinger, Christian;
    • Aslam, Muhammad;
    • Naeem, Farooq;
    • Schmidt, Kurt;
    • Gruber, Karl;
    • Speicher, Michael R.;
    • Malle, Ernst;
    • Macheroux, Peter;
    • Ayub, Muhammad;
    • Vincent, John B.;
    • Windpassinger, Christian;
    • Duba, Hans-Christoph
    Publication type:
    Article
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    Enzyme discovery beyond homology: a unique hydroxynitrile lyase in the Bet v1 superfamily.

    Published in:
    Scientific Reports, 2017, p. 46738, doi. 10.1038/srep46738
    By:
    • Lanfranchi, Elisa;
    • Pavkov-Keller, Tea;
    • Koehler, Eva-Maria;
    • Diepold, Matthias;
    • Steiner, Kerstin;
    • Darnhofer, Barbara;
    • Hartler, Jürgen;
    • Van Den Bergh, Tom;
    • Joosten, Henk-Jan;
    • Gruber-Khadjawi, Mandana;
    • Thallinger, Gerhard G.;
    • Birner-Gruenberger, Ruth;
    • Gruber, Karl;
    • Winkler, Margit;
    • Glieder, Anton
    Publication type:
    Article
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