Works by Grotzinger, Carsten

Results: 37

ICAM1 depletion reduces spinal metastasis formation in vivo and improves neurological outcome.

Published in:

2015

By:

Broggini, Thomas;
Czabanka, Marcus;
Piffko, Andras;
Harms, Christoph;
Hoffmann, Christian;
Mrowka, Ralf;
Wenke, Frank;
Deutsch, Urban;
Grötzinger, Carsten;
Vajkoczy, Peter;
Grötzinger, Carsten

Publication type:

journal article

Knockin' on pHeaven's Door: A Fast and Reliable High-Throughput Compatible Zero-Background Cloning Procedure.

Published in:

Molecular Biotechnology, 2014, v. 56, n. 5, p. 449, doi. 10.1007/s12033-014-9736-2

By:

Schefer, Quirino;
Hallmann, Sandy;
Grötzinger, Carsten

Publication type:

Article

Transcriptomic Deconvolution of Neuroendocrine Neoplasms Predicts Clinically Relevant Characteristics.

Published in:

Cancers, 2023, v. 15, n. 3, p. 936, doi. 10.3390/cancers15030936

By:

Otto, Raik;
Detjen, Katharina M.;
Riemer, Pamela;
Fattohi, Melanie;
Grötzinger, Carsten;
Rindi, Guido;
Wiedenmann, Bertram;
Sers, Christine;
Leser, Ulf

Publication type:

Article

A Chemerin Peptide Analog Stimulates Tumor Growth in Two Xenograft Mouse Models of Human Colorectal Carcinoma.

Published in:

Cancers, 2022, v. 14, n. 1, p. 125, doi. 10.3390/cancers14010125

By:

Friebus-Kardash, Justa;
Schulz, Petra;
Reinicke, Sandy;
Karthaus, Cordula;
Schefer, Quirino;
Bandholtz, Sebastian;
Grötzinger, Carsten

Publication type:

Article

Elevated Flt3L Predicts Long-Term Survival in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms.

Published in:

Cancers, 2021, v. 13, n. 17, p. 4463, doi. 10.3390/cancers13174463

By:

Detjen, Katharina M.;
Otto, Raik;
Giesecke, Yvonne;
Geisler, Lukas;
Riemer, Pamela;
Jann, Henning;
Grötzinger, Carsten;
Sers, Christine;
Pascher, Andreas;
Lüdde, Tom;
Leser, Ulf;
Wiedenmann, Bertram;
Sigal, Michael;
Tacke, Frank;
Roderburg, Christoph;
Hammerich, Linda

Publication type:

Article

Systematic Identification of MACC1-Driven Metabolic Networks in Colorectal Cancer.

Published in:

Cancers, 2021, v. 13, n. 5, p. 978, doi. 10.3390/cancers13050978

By:

Lisec, Jan;
Kobelt, Dennis;
Walther, Wolfgang;
Mokrizkij, Margarita;
Grötzinger, Carsten;
Jaeger, Carsten;
Baum, Katharina;
Simon, Mareike;
Wolf, Jana;
Beindorff, Nicola;
Brenner, Winfried;
Stein, Ulrike;
O'Connell, Thomas M.;
Jia, Wei

Publication type:

Article

AGTR1 Is Overexpressed in Neuroendocrine Neoplasms, Regulates Secretion and May Potentially Serve as a Target for Molecular Imaging and Therapy.

Published in:

Cancers, 2020, v. 12, n. 11, p. 3138, doi. 10.3390/cancers12113138

By:

Exner, Samantha;
Schuldt, Claudia;
Sachindra, Sachindra;
Du, Jing;
Heing-Becker, Isabelle;
Licha, Kai;
Wiedenmann, Bertram;
Grötzinger, Carsten

Publication type:

Article

Secretin Receptor as a Target in Gastrointestinal Cancer: Expression Analysis and Ligand Development.

Published in:

Biomedicines, 2022, v. 10, n. 3, p. 536, doi. 10.3390/biomedicines10030536

By:

Klussmeier, Anja;
Aurich, Stefan;
Niederstadt, Lars;
Wiedenmann, Bertram;
Grötzinger, Carsten

Publication type:

Article

Sodium Butyrate Increases Expression of the Coxsackie and Adenovirus Receptor in Colon Cancer Cells.

Published in:

Cancer Investigation, 2010, v. 28, n. 3, p. 268, doi. 10.3109/07357900902783195

By:

Küster, Katrin;
Grötzinger, Carsten;
Koschel, Annika;
Fischer, Andreas;
Wiedenmann, Bertram;
Anders, Mario

Publication type:

Article

SV40 large T-antigen disturbs the formation of nuclear DNA-repair foci containing MRE11.

Published in:

Oncogene, 2002, v. 21, n. 32, p. 4873, doi. 10.1038/sj.onc.1205616

By:

Digweed, Martin;
Demuth, Ilja;
Rothe, Susanne;
Scholz, Regina;
Jordan, Andreas;
Grotzinger, Carsten;
Schindler, Detlev;
Grompe, Markus;
Sperling, Karl

Publication type:

Article

Transient Receptor Potential Channel TRPM8 Agonists Stimulate Calcium Influx and Neurotensin Secretion in Neuroendocrine Tumor Cells.

Published in:

Neuroendocrinology, 2007, v. 85, n. 2, p. 81, doi. 10.1159/000101693

By:

Mergler, Stefan;
Strowski, Mathias Z.;
Kaiser, Simone;
Plath, Thomas;
Giesecke, Yvonne;
Neumann, Marleen;
Hosokawa, Hiroshi;
Kobayashi, Shigeo;
Langrehr, Jan;
Neuhaus, Peter;
Plöckinger, Ursula;
Wiedenmann, Bertram;
Grötzinger, Carsten

Publication type:

Article

Tumour Biology of Gastroenteropancreatic Neuroendocrine Tumours.

Published in:

Neuroendocrinology, 2004, v. 80, p. 8, doi. 10.1159/000080732

By:

Grötzinger, Carsten

Publication type:

Article

Octreotide Does Not Inhibit Proliferation in Five Neuroendocrine Tumor Cell Lines.

Published in:

Frontiers in Endocrinology, 2018, p. 1, doi. 10.3389/fendo.2018.00146

By:

Exner, Samantha;
Prasad, Vikas;
Wiedenmann, Bertram;
Grötzinger, Carsten

Publication type:

Article

A Cyanine‐Bridged Somatostatin Hybrid Probe for Multimodal SSTR2 Imaging in Vitro and in Vivo: Synthesis and Evaluation.

Published in:

ChemBioChem, 2021, v. 22, n. 7, p. 1307, doi. 10.1002/cbic.202000791

By:

Heing‐Becker, Isabelle;
Grötzinger, Carsten;
Beindorff, Nicola;
Prasad, Sonal;
Erdmann, Sarah;
Exner, Samantha;
Haag, Rainer;
Licha, Kai

Publication type:

Article

Near-Infrared Confocal Laser Endomicroscopy Detects Colorectal Cancer via an Integrin αvβ 3 Optical Probe.

Published in:

2015

By:

Schulz, Petra;
Dierkes, Cordula;
Wiedenmann, Bertram;
Grötzinger, Carsten

Publication type:

journal article

Near-Infrared Confocal Laser Endomicroscopy Detects Colorectal Cancer via an Integrin αβ Optical Probe.

Published in:

Molecular Imaging & Biology, 2015, v. 17, n. 4, p. 450, doi. 10.1007/s11307-015-0825-9

By:

Schulz, Petra;
Dierkes, Cordula;
Wiedenmann, Bertram;
Grötzinger, Carsten

Publication type:

Article

Increasing molar activity by HPLC purification improves 68Ga-DOTA-NAPamide tumor accumulation in a B16/F1 melanoma xenograft model.

Published in:

PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0217883

By:

von Hacht, Jan Lennart;
Erdmann, Sarah;
Niederstadt, Lars;
Prasad, Sonal;
Wagener, Asja;
Exner, Samantha;
Beindorff, Nicola;
Brenner, Winfried;
Grötzinger, Carsten

Publication type:

Article

A colorectal cancer classification system that associates cellular phenotype and responses to therapy.

Published in:

Nature Medicine, 2013, v. 19, n. 5, p. 619, doi. 10.1038/nm.3175

By:

Sadanandam, Anguraj;
Lyssiotis, Costas A;
Homicsko, Krisztian;
Collisson, Eric A;
Gibb, William J;
Wullschleger, Stephan;
Ostos, Liliane C Gonzalez;
Lannon, William A;
Grotzinger, Carsten;
Del Rio, Maguy;
Lhermitte, Benoit;
Olshen, Adam B;
Wiedenmann, Bertram;
Cantley, Lewis C;
Gray, Joe W;
Hanahan, Douglas

Publication type:

Article

Dual-wavelength 3D photoacoustic imaging of mammalian cells using a photoswitchable phytochrome reporter protein.

Published in:

Communications Physics, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42005-017-0003-2

By:

Märk, Julia;
Dortay, Hakan;
Wagener, Asja;
Zhang, Edward;
Buchmann, Jens;
Grötzinger, Carsten;
Friedrich, Thomas;
Laufer, Jan

Publication type:

Article

A complete substitutional analysis of VIP for better tumor imaging properties.

Published in:

Journal of Molecular Recognition, 2002, v. 15, n. 3, p. 145, doi. 10.1002/jmr.565

By:

Bhargava, Sarah;
Licha, Kai;
Knaute, Tobias;
Ebert, Bernd;
Becker, Andreas;
Grötzinger, Carsten;
Hessenius, Carsten;
Wiedenmann, Bertram;
Schneider-Mergener, Jens;
Volkmer-Engert, Rudolf

Publication type:

Article

The selective PI3Kα inhibitor BYL719 as a novel therapeutic option for neuroendocrine tumors: Results from multiple cell line models.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0182852

By:

Nölting, Svenja;
Rentsch, Jakob;
Freitag, Helma;
Detjen, Katharina;
Briest, Franziska;
Möbs, Markus;
Weissmann, Victoria;
Siegmund, Britta;
Auernhammer, Christoph J.;
Aristizabal Prada, Elke Tatjana;
Lauseker, Michael;
Grossman, Ashley;
Exner, Samantha;
Fischer, Christian;
Grötzinger, Carsten;
Schrader, Jörg;
Grabowski, Patricia;
null, null

Publication type:

Article

Cyanine Dye Labeled Vasoactive Intestinal Peptide and Somatostatin Analog for Optical Detection of Gastroenteropancreatic Tumors.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 921, n. 1, p. 275, doi. 10.1111/j.1749-6632.2000.tb06976.x

By:

BECKER, ANDREAS;
HESSENIUS, CARSTEN;
BHARGAVA, SARAH;
GRÖTZINGER, CARSTEN;
LICHA, KAI;
SCHNEIDER-MERGENER, JENS;
WIEDENMANN, BERTRAM;
SEMMLER, WOLFHARD

Publication type:

Article

Is the Neuropeptide PEN a Ligand of GPR83?

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 20, p. 15117, doi. 10.3390/ijms242015117

By:

Giesecke, Yvonne;
Asimi, Vahid;
Stulberg, Valentina;
Kleinau, Gunnar;
Scheerer, Patrick;
Koksch, Beate;
Grötzinger, Carsten

Publication type:

Article

Somatostatin Receptor Targeting for Tumor Imaging and Therapy.

Published in:

Annals of the New York Academy of Sciences, 2004, v. 1014, n. 1, p. 258, doi. 10.1196/annals.1294.028

By:

GRÖTZINGER, CARSTEN;
WIEDENMANN, BERTRAM

Publication type:

Article

Ring Finger Protein 11 Inhibits Melanocortin 3 and 4 Receptor Signaling.

Published in:

Frontiers in Endocrinology, 2016, p. 1, doi. 10.3389/fendo.2016.00109

By:

Müller, Anne;
Niederstadt, Lars;
Jonas, Wenke;
Chun-Xia Yi;
Meyer, Franziska;
Wiedmer, Petra;
Fischer, Jana;
Grötzinger, Carsten;
Schürmann, Annette;
Tschöp, Matthias;
Kleinau, Gunnar;
Grüters, Annette;
Krude, Heiko;
Biebermann, Heike

Publication type:

Article

The Application of Dual‐Layer, Mussel‐Inspired, Antifouling Polyglycerol‐Based Coatings in Ventricular Assist Devices.

Published in:

Advanced Materials Interfaces, 2020, v. 7, n. 21, p. 1, doi. 10.1002/admi.202000272

By:

Kulka, Michaël W.;
Smatty, Sarah;
Hehnen, Felix;
Bierewirtz, Tim;
Silberreis, Kim;
Nie, Chuanxiong;
Kerkhoff, Yannic;
Grötzinger, Carsten;
Friedrich, Sebastian;
Dahms, Lars Ingemar;
Dernedde, Jens;
Grunwald, Ingo;
Schirner, Michael;
Kertzscher, Ulrich;
Affeld, Klaus;
Haag, Rainer

Publication type:

Article

mTOR Inhibitors as Radiosensitizers in Neuroendocrine Neoplasms.

Published in:

Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2020.578380

By:

Exner, Samantha;
Arrey, Gerard;
Prasad, Vikas;
Grötzinger, Carsten

Publication type:

Article

Non‐invasive metastasis prognosis from plasma metabolites in stage II colorectal cancer patients: The DACHS study.

Published in:

International Journal of Cancer, 2019, v. 145, n. 1, p. 221, doi. 10.1002/ijc.32076

By:

Zaimenko, Inna;
Jaeger, Carsten;
Brenner, Hermann;
Chang‐Claude, Jenny;
Hoffmeister, Michael;
Grötzinger, Carsten;
Detjen, Katharina;
Burock, Susen;
Schmitt, Clemens A.;
Stein, Ulrike;
Lisec, Jan

Publication type:

Article

Molecular Evolution of a Peptide GPCR Ligand Driven by Artificial Neural Networks.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036948

By:

Bandholtz, Sebastian;
Wichard, Jörg;
Kühne, Ronald;
Grötzinger, Carsten

Publication type:

Article

Multimodal imaging of two-cycle PRRT with 177Lu-DOTA-JR11 and 177Lu-DOTATOC in an orthotopic neuroendocrine xenograft tumor mouse model.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 12, p. 1, doi. 10.2967/jnumed.120.250274

By:

Albrecht, Jakob;
Exner, Samantha;
Grötzinger, Carsten;
Prasad, Sonal;
Konietschke, Frank;
Beindorff, Nicola;
Kühl, Anja A.;
Prasad, Vikas;
Brenner, Winfried;
Koziolek, Eva J.

Publication type:

Article

Multimodal imaging of two-cycle PRRT with 177Lu-DOTA-JR11 and 177Lu-DOTATOC in an orthotopic neuroendocrine xenograft tumor mouse model.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 11, p. 1, doi. 10.2967/jnumed.120.250274

By:

Albrecht, Jakob;
Exner, Samantha;
Grötzinger, Carsten;
Prasad, Sonal;
Konietschke, Frank;
Beindorff, Nicola;
Kühl, Anja A.;
Prasad, Vikas;
Brenner, Winfried;
Koziolek, Eva J.

Publication type:

Article

Multimodal imaging of two-cycle PRRT with 177Lu-DOTA-JR11 and 177Lu-DOTATOC in an orthotopic neuroendocrine xenograft tumor mouse model.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 10, p. 1, doi. 10.2967/jnumed.120.250274

By:

Albrecht, Jakob;
Exner, Samantha;
Grötzinger, Carsten;
Prasad, Sonal;
Konietschke, Frank;
Beindorff, Nicola;
Kühl, Anja A.;
Prasad, Vikas;
Brenner, Winfried;
Koziolek, Eva J.

Publication type:

Article

Multimodal imaging of two-cycle PRRT with 177Lu-DOTA-JR11 and 177Lu-DOTATOC in an orthotopic neuroendocrine xenograft tumor mouse model.

Published in:

Journal of Nuclear Medicine, 2020, v. 61, n. 9, p. 1, doi. 10.2967/jnumed.120.250274

By:

Albrecht, Jakob;
Exner, Samantha;
Grötzinger, Carsten;
Prasad, Sonal;
Konietschke, Frank;
Beindorff, Nicola;
Kühl, Anja A.;
Prasad, Vikas;
Brenner, Winfried;
Koziolek, Eva J.

Publication type:

Article

miR-223 and Chromogranin A Affect Inflammatory Immune Cell Activation in Liver Metastasis of Neuroendocrine Neoplasms.

Published in:

Cells (2073-4409), 2025, v. 14, n. 2, p. 111, doi. 10.3390/cells14020111

By:

Geisler, Lukas;
Detjen, Katharina;
Hellberg, Teresa;
Kohlhepp, Marlene;
Grötzinger, Carsten;
Knorr, Jana;
Eichhorn, Ines;
Mohr, Raphael;
Holtmann, Theresa;
Wiedenmann, Bertram;
Tacke, Frank;
Roderburg, Christoph;
Wree, Alexander

Publication type:

Article

SPECT/CT Imaging, Biodistribution and Radiation Dosimetry of a 177Lu-DOTA-Integrin αvβ6 Cystine Knot Peptide in a Pancreatic Cancer Xenograft Model.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.684713

By:

Sachindra, Sachindra;
Hellberg, Teresa;
Exner, Samantha;
Prasad, Sonal;
Beindorff, Nicola;
Rogalla, Stephan;
Kimura, Richard;
Gambhir, Sanjiv Sam;
Wiedenmann, Bertram;
Grötzinger, Carsten

Publication type:

Article

Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands.

Published in:

Nature Biotechnology, 2001, v. 19, n. 4, p. 327, doi. 10.1038/86707

By:

Becker, Andreas;
Hessenius, Carsten;
Licha, Kai;
Ebert, Bernd;
Sukowski, Uwe;
Semmler, Wolfhard;
Wiedenmann, Bertram;
Grötzinger, Carsten

Publication type:

Article

Orexin-a Inhibits Glucagon Secretion and Gene Expression.

Published in:

Diabetes, 2007, v. 56, p. A379

By:

Göncz, Eva;
Grötzinger, Carsten;
Mergler, Stefan;
El-Zayat, Bilal F.;
Theodoropoulou, Marily;
Stalla, Günter K.;
Wiedenmann, Bertram;
Strowski, Mathias Z.;
Plöckinger, Ursula

Publication type:

Article

Works by Grotzinger, Carsten

ICAM1 depletion reduces spinal metastasis formation in vivo and improves neurological outcome.

Knockin' on pHeaven's Door: A Fast and Reliable High-Throughput Compatible Zero-Background Cloning Procedure.

Transcriptomic Deconvolution of Neuroendocrine Neoplasms Predicts Clinically Relevant Characteristics.

A Chemerin Peptide Analog Stimulates Tumor Growth in Two Xenograft Mouse Models of Human Colorectal Carcinoma.

Elevated Flt3L Predicts Long-Term Survival in Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms.

Systematic Identification of MACC1-Driven Metabolic Networks in Colorectal Cancer.

AGTR1 Is Overexpressed in Neuroendocrine Neoplasms, Regulates Secretion and May Potentially Serve as a Target for Molecular Imaging and Therapy.

Secretin Receptor as a Target in Gastrointestinal Cancer: Expression Analysis and Ligand Development.

Sodium Butyrate Increases Expression of the Coxsackie and Adenovirus Receptor in Colon Cancer Cells.

SV40 large T-antigen disturbs the formation of nuclear DNA-repair foci containing MRE11.

Transient Receptor Potential Channel TRPM8 Agonists Stimulate Calcium Influx and Neurotensin Secretion in Neuroendocrine Tumor Cells.

Tumour Biology of Gastroenteropancreatic Neuroendocrine Tumours.

Octreotide Does Not Inhibit Proliferation in Five Neuroendocrine Tumor Cell Lines.

A Cyanine‐Bridged Somatostatin Hybrid Probe for Multimodal SSTR2 Imaging in Vitro and in Vivo: Synthesis and Evaluation.

Near-Infrared Confocal Laser Endomicroscopy Detects Colorectal Cancer via an Integrin αvβ 3 Optical Probe.

Near-Infrared Confocal Laser Endomicroscopy Detects Colorectal Cancer via an Integrin αβ Optical Probe.

Increasing molar activity by HPLC purification improves <sup>68</sup>Ga-DOTA-NAPamide tumor accumulation in a B16/F1 melanoma xenograft model.

A colorectal cancer classification system that associates cellular phenotype and responses to therapy.

Dual-wavelength 3D photoacoustic imaging of mammalian cells using a photoswitchable phytochrome reporter protein.

A complete substitutional analysis of VIP for better tumor imaging properties.

The selective PI3Kα inhibitor BYL719 as a novel therapeutic option for neuroendocrine tumors: Results from multiple cell line models.

Cyanine Dye Labeled Vasoactive Intestinal Peptide and Somatostatin Analog for Optical Detection of Gastroenteropancreatic Tumors.

Is the Neuropeptide PEN a Ligand of GPR83?

Somatostatin Receptor Targeting for Tumor Imaging and Therapy.

Ring Finger Protein 11 Inhibits Melanocortin 3 and 4 Receptor Signaling.

The Application of Dual‐Layer, Mussel‐Inspired, Antifouling Polyglycerol‐Based Coatings in Ventricular Assist Devices.

mTOR Inhibitors as Radiosensitizers in Neuroendocrine Neoplasms.

Non‐invasive metastasis prognosis from plasma metabolites in stage II colorectal cancer patients: The DACHS study.

Molecular Evolution of a Peptide GPCR Ligand Driven by Artificial Neural Networks.

Multimodal imaging of two-cycle PRRT with <sup>177</sup>Lu-DOTA-JR11 and <sup>177</sup>Lu-DOTATOC in an orthotopic neuroendocrine xenograft tumor mouse model.

Multimodal imaging of two-cycle PRRT with <sup>177</sup>Lu-DOTA-JR11 and <sup>177</sup>Lu-DOTATOC in an orthotopic neuroendocrine xenograft tumor mouse model.

Multimodal imaging of two-cycle PRRT with 177Lu-DOTA-JR11 and <sup>177</sup>Lu-DOTATOC in an orthotopic neuroendocrine xenograft tumor mouse model.

Multimodal imaging of two-cycle PRRT with <sup>177</sup>Lu-DOTA-JR11 and <sup> 177</sup>Lu-DOTATOC in an orthotopic neuroendocrine xenograft tumor mouse model.

miR-223 and Chromogranin A Affect Inflammatory Immune Cell Activation in Liver Metastasis of Neuroendocrine Neoplasms.

SPECT/CT Imaging, Biodistribution and Radiation Dosimetry of a <sup>177</sup>Lu-DOTA-Integrin αvβ6 Cystine Knot Peptide in a Pancreatic Cancer Xenograft Model.

Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands.

Orexin-a Inhibits Glucagon Secretion and Gene Expression.