Works by Grosveld, Gerard C

Results: 19

γ-secretase inhibitors: Notch so bad.

Published in:

Nature Medicine, 2009, v. 15, n. 1, p. 20, doi. 10.1038/nm0109-20

By:

Grosveld, Gerard C.

Publication type:

Article

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype.

Published in:

Nature Medicine, 2001, v. 7, n. 9, p. 1028, doi. 10.1038/nm0901-1028

By:

Zhou, Sheng;
Schuetz, John D.;
Bunting, Kevin D.;
Colapietro, Anne-Marie;
Sampath, Janardhan;
Morris, John J.;
Lagutina, Irina;
Grosveld, Gerard C.;
Osawa, Mitsujiro;
Nakauchi, Hiromitsu;
Sorrentino, Brian P.

Publication type:

Article

Phosphorylation of TSC2 by PKC-δ reveals a novel signaling pathway that couples protein synthesis to mTORC1 activity.

Published in:

Molecular & Cellular Biochemistry, 2019, v. 456, n. 1/2, p. 123, doi. 10.1007/s11010-019-03498-8

By:

Zhan, Jun;
Chitta, Raghu K.;
Harwood, Frank C.;
Grosveld, Gerard C.

Publication type:

Article

FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma.

Published in:

Journal of Cell Biology, 2005, v. 170, n. 6, p. 903, doi. 10.1083/jcb.200501040

By:

Bois, Philippe R. J.;
Lzeradjene, Kamel;
Houghton, Peter J.;
Cleveland, John L.;
Houghton, Janet A.;
Grosveld, Gerard C.

Publication type:

Article

IRIZIO: a novel gene cooperating with PAX3-FOXO1 in alveolar rhabdomyosarcoma (ARMS).

Published in:

Carcinogenesis, 2011, v. 32, n. 4, p. 452, doi. 10.1093/carcin/bgq273

By:

Picchione, Fabrizio;
Pritchard, Colin;
Lagutina, Irina;
Janke, Laura;
Grosveld, Gerard C.

Publication type:

Article

Mapping of MN1 Sequences Necessary for Myeloid Transformation.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061706

By:

Kandilci, Ayten;
Surtel, Jacqueline;
Janke, Laura;
Neale, Geoffrey;
Terranova, Sabrina;
Grosveld, Gerard C.

Publication type:

Article

The Leukemia-Associated Fusion Protein MN1-TEL Blocks TEL-Specific Recognition Sequences.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046085

By:

ter Haar, W. Martijn;
Meester-Smoor, Magda A.;
Van Wely, Karel H. M.;
Schot, Claudia C. M. M.;
Janssen, Marjolein J. F. W.;
Geverts, Bart;
Bonten, Jacqueline;
Grosveld, Gerard C.;
Houtsmuller, Adriaan B.;
Zwarthoff, Ellen C.;
Bunting, Kevin D.

Publication type:

Article

The MN1 oncoprotein synergizes with coactivators RAC3 and p300 in RAR-RXR-mediated transcription.

Published in:

Oncogene, 2003, v. 22, n. 5, p. 699, doi. 10.1038/sj.onc.1206124

By:

van Wely, Karel H M;
Molijn, Anco C;
Buijs, Arjan;
Meester-Smoor, Magda A;
Aarnoudse, Albert Jan;
Hellemons, Anita;
den Besten, Pim;
Grosveld, Gerard C;
Zwarthoff, Ellen C

Publication type:

Article

FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts.

Published in:

EMBO Journal, 2003, v. 22, n. 5, p. 1147, doi. 10.1093/emboj/cdg116

By:

Bois, Philippe R. J.;
Grosveld, Gerard C.

Publication type:

Article

FoxO1a-Cyclic GMP-Dependent Kinase I Interactions Orchestrate Myoblast Fusion.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 17, p. 7645, doi. 10.1128/MCB.25.17.7645-7656.2005

By:

Bois, Philippe R. J.;
Brochard, Vanessa F.;
Salin-Cantegrel, Adèle V. A.;
Cleveland, John L.;
Grosveld, Gerard C.

Publication type:

Article

The Novel ETS Factor TEL2 Cooperates with Myc in B Lymphomagenesis.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 6, p. 2395, doi. 10.1128/MCB.25.6.2395-2405.2005

By:

Monica Cardone;
Ayten Kandilci;
Cintia Carella;
Jonas A. Nilsson;
Jennifer A. Brennan;
Sema Sirma;
Ugur Ozbek;
Kelli Boyd;
John L. Cleveland;
Gerard C. Grosveld

Publication type:

Article

Haploinsufficiency of the lysosomal sialidase NEU1 results in a model of pleomorphic rhabdomyosarcoma in mice.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03968-8

By:

Machado, Eda R.;
van de Vlekkert, Diantha;
Sheppard, Heather S.;
Perry, Scott;
Downing, Susanna M.;
Laxton, Jonathan;
Ashmun, Richard;
Finkelstein, David B.;
Neale, Geoffrey A.;
Hu, Huimin;
Harwood, Frank C.;
Koo, Selene C.;
Grosveld, Gerard C.;
d'Azzo, Alessandra

Publication type:

Article

Establishment of a transgenic mouse to model ETV7 expressing human tumors.

Published in:

Transgenic Research, 2019, v. 28, n. 1, p. 115, doi. 10.1007/s11248-018-0104-z

By:

Numata, Masashi;
Klein Geltink, R. I.;
Grosveld, Gerard C.

Publication type:

Article

MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11568-0

By:

Annunziata, Ida;
van de Vlekkert, Diantha;
Machado, Eda;
Mosca, Rosario;
Campos, Yvan;
Qiu, Xiaohui;
Grosveld, Gerard C.;
d'Azzo, Alessandra;
Andrew Weesner, Jason;
Ellen Fremuth, Leigh;
Wolf, Elmar;
Finkelstein, David;
Neale, Geoffrey;
Tillman, Heather;
Roussel, Martine F.;
Han, Min-Joon

Publication type:

Article

Assembly of mTORC3 Involves Binding of ETV7 to Two Separate Sequences in the mTOR Kinase Domain.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 18, p. 10042, doi. 10.3390/ijms251810042

By:

Zhan, Jun;
Harwood, Frank;
Have, Sara Ten;
Lamond, Angus;
Phillips, Aaron H.;
Kriwacki, Richard W.;
Halder, Priyanka;
Cardone, Monica;
Grosveld, Gerard C.

Publication type:

Article

PAX3-FOXO1 and FGFR4 in alveolar rhabdomyosarcoma.

Published in:

Molecular Carcinogenesis, 2012, v. 51, n. 10, p. 807, doi. 10.1002/mc.20848

By:

Marshall, Amy D.;
van der Ent, Martijn A.;
Grosveld, Gerard C.

Publication type:

Article

MN1 affects expression of genes involved in hematopoiesis and can enhance as well as inhibit RAR/RXR-induced gene expression.

Published in:

Carcinogenesis, 2008, v. 29, n. 10, p. 2025, doi. 10.1093/carcin/bgn168

By:

Magda A. Meester-Smoor;
Marjolein J.F.W. Janssen;
Gerard C. Grosveld;
Annelies de Klein;
Wilfred F.J. van IJcken;
Hannie Douben;
Ellen C. Zwarthoff

Publication type:

Article

Alveolar rhabdomyosarcoma - The molecular drivers of PAX3/7-FOXO1-induced tumorigenesis.

Published in:

Skeletal Muscle, 2012, v. 2, n. 1, p. 1, doi. 10.1186/2044-5040-2-25

By:

Marshall, Amy D.;
Grosveld, Gerard C.

Publication type:

Article

Modeling of the Human Alveolar Rhabdomyosarcoma Pax3-Foxo1 Chromosome Translocation in Mouse Myoblasts Using CRISPR-Cas9 Nuclease.

Published in:

PLoS Genetics, 2015, v. 11, n. 2, p. 1, doi. 10.1371/journal.pgen.1004951

By:

Lagutina, Irina V.;
Valentine, Virginia;
Picchione, Fabrizio;
Harwood, Frank;
Valentine, Marcus B.;
Villarejo-Balcells, Barbara;
Carvajal, Jaime J.;
Grosveld, Gerard C.

Publication type:

Article