Works by Grossmann, Tom N.

Results: 69

Binding Dynamics of a Stapled Peptide Targeting the Transcription Factor NF−Y.

Published in:

ChemBioChem, 2024, v. 25, n. 9, p. 1, doi. 10.1002/cbic.202400020

By:

Durukan, Canan;
Arbore, Federica;
Klintrot, Rasmus;
Bigiotti, Carlo;
Ilie, Ioana M.;
Vreede, Jocelyne;
Grossmann, Tom N.;
Hennig, Sven

Publication type:

Article

Protein Macrocyclization for Tertiary Structure Stabilization.

Published in:

ChemBioChem, 2021, v. 22, n. 17, p. 2672, doi. 10.1002/cbic.202100111

By:

Haim, Anissa;
Neubacher, Saskia;
Grossmann, Tom N.

Publication type:

Article

Cover Feature: Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119 (ChemBioChem 24/2019).

Published in:

ChemBioChem, 2019, v. 20, n. 24, p. 2971, doi. 10.1002/cbic.201900704

By:

Cromm, Philipp M.;
Adihou, Hélène;
Kapoor, Shobhna;
Vazquez‐Chantada, Mercedes;
Davey, Paul;
Longmire, David;
Hennes, Elisabeth;
Hofer, Walter;
Küchler, Philipp;
Chiarparin, Elisabetta;
Waldmann, Herbert;
Grossmann, Tom N.

Publication type:

Article

Lipidated Stapled Peptides Targeting the Acyl Binding Protein UNC119.

Published in:

ChemBioChem, 2019, v. 20, n. 24, p. 2987, doi. 10.1002/cbic.201900615

By:

Cromm, Philipp M.;
Adihou, Hélène;
Kapoor, Shobhna;
Vazquez‐Chantada, Mercedes;
Davey, Paul;
Longmire, David;
Hennes, Elisabeth;
Hofer, Walter;
Küchler, Philipp;
Chiarparin, Elisabetta;
Waldmann, Herbert;
Grossmann, Tom N.

Publication type:

Article

Constraining an Irregular Peptide Secondary Structure through Ring-Closing Alkyne Metathesis.

Published in:

ChemBioChem, 2016, v. 17, n. 20, p. 1915, doi. 10.1002/cbic.201600362

By:

Cromm, Philipp M.;
Wallraven, Kerstin;
Glas, Adrian;
Bier, David;
Fürstner, Alois;
Ottmann, Christian;
Grossmann, Tom N.

Publication type:

Article

Reversible und kovalente Inhibition eines Zielproteins.

Published in:

Angewandte Chemie, 2012, v. 124, n. 35, p. 8829, doi. 10.1002/ange.201203341

By:

Lee, Chang-Uk;
Grossmann, Tom N.

Publication type:

Article

DNA-gesteuerte Synthese und Bioaktivität proapoptotischer Peptide.

Published in:

Angewandte Chemie, 2011, v. 123, n. 12, p. 2880, doi. 10.1002/ange.201007103

By:

Erben, Anne;
Grossmann, Tom N.;
Seitz, Oliver

Publication type:

Article

New aspects in fragmentation of peptide nucleic acids: comparison of positive and negative ions by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2009, v. 23, n. 8, p. 1132, doi. 10.1002/rcm.3979

By:

Ziehe, Matthias;
Grossmann, Tom N.;
Seitz, Oliver;
Linscheid, Michael W.

Publication type:

Article

Synergistic DNA‐ and Protein‐Based Recognition Promote an RNA‐Templated Bio‐orthogonal Reaction.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 40, p. 10477, doi. 10.1002/chem.202101103

By:

McLoughlin, Niall M.;
Kuepper, Arne;
Neubacher, Saskia;
Grossmann, Tom N.

Publication type:

Article

Environment‐Responsive Peptide Dimers Bind and Stabilize Double‐Stranded RNA.

Published in:

Angewandte Chemie, 2023, v. 135, n. 41, p. 1, doi. 10.1002/ange.202308028

By:

McLoughlin, Niall M.;
Albers, Marvin A.;
Collado Camps, Estel;
Paulus, Jannik;
Ran, Youri A.;
Neubacher, Saskia;
Hennig, Sven;
Brock, Roland;
Grossmann, Tom N.

Publication type:

Article

Rücktitelbild: Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling (Angew. Chem. 25/2021).

Published in:

Angewandte Chemie, 2021, v. 133, n. 25, p. 14316, doi. 10.1002/ange.202104892

By:

Wendt, Mathias;
Bellavita, Rosa;
Gerber, Alan;
Efrém, Nina‐Louisa;
Ramshorst, Thirza;
Pearce, Nicholas M.;
Davey, Paul R. J.;
Everard, Isabel;
Vazquez‐Chantada, Mercedes;
Chiarparin, Elisabetta;
Grieco, Paolo;
Hennig, Sven;
Grossmann, Tom N.

Publication type:

Article

Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling.

Published in:

Angewandte Chemie, 2021, v. 133, n. 25, p. 14056, doi. 10.1002/ange.202102082

By:

Wendt, Mathias;
Bellavita, Rosa;
Gerber, Alan;
Efrém, Nina‐Louisa;
Ramshorst, Thirza;
Pearce, Nicholas M.;
Davey, Paul R. J.;
Everard, Isabel;
Vazquez‐Chantada, Mercedes;
Chiarparin, Elisabetta;
Grieco, Paolo;
Hennig, Sven;
Grossmann, Tom N.

Publication type:

Article

Constrained Peptides with Fine‐Tuned Flexibility Inhibit NF‐Y Transcription Factor Assembly.

Published in:

Angewandte Chemie, 2019, v. 131, n. 48, p. 17512, doi. 10.1002/ange.201907901

By:

Jeganathan, Sadasivam;
Wendt, Mathias;
Kiehstaller, Sebastian;
Brancaccio, Diego;
Kuepper, Arne;
Pospiech, Nicole;
Carotenuto, Alfonso;
Novellino, Ettore;
Hennig, Sven;
Grossmann, Tom N.

Publication type:

Article

Innenrücktitelbild: Coiled‐Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection (Angew. Chem. 52/2018).

Published in:

Angewandte Chemie, 2018, v. 130, n. 52, p. 17513, doi. 10.1002/ange.201813484

By:

Mueller, Carolin;
Grossmann, Tom N.

Publication type:

Article

Coiled‐Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection.

Published in:

Angewandte Chemie, 2018, v. 130, n. 52, p. 17325, doi. 10.1002/ange.201811515

By:

Mueller, Carolin;
Grossmann, Tom N.

Publication type:

Article

Frontispiz: In Situ Cyclization of Native Proteins: Structure‐Based Design of a Bicyclic Enzyme.

Published in:

Angewandte Chemie, 2018, v. 130, n. 35, p. 1, doi. 10.1002/ange.201883561

By:

Pelay‐Gimeno, Marta;
Bange, Tanja;
Hennig, Sven;
Grossmann, Tom N.

Publication type:

Article

In Situ Cyclization of Native Proteins: Structure‐Based Design of a Bicyclic Enzyme.

Published in:

Angewandte Chemie, 2018, v. 130, n. 35, p. 11334, doi. 10.1002/ange.201804506

By:

Pelay‐Gimeno, Marta;
Bange, Tanja;
Hennig, Sven;
Grossmann, Tom N.

Publication type:

Article

Helicity‐Dependent Enzymatic Peptide Cyclization.

Published in:

Journal of Peptide Science, 2025, v. 31, n. 6, p. 1, doi. 10.1002/psc.70024

By:

Durukan, Canan;
Faierson, Jannik;
van der Wal, Isabel;
Pérez, Juan Lizandra;
Hennig, Sven;
Grossmann, Tom N.

Publication type:

Article

Peptide‐based covalent inhibitors of protein–protein interactions.

Published in:

Journal of Peptide Science, 2023, v. 29, n. 1, p. 1, doi. 10.1002/psc.3457

By:

Paulussen, Felix M.;
Grossmann, Tom N.

Publication type:

Article

Stapling of Peptides Potentiates the Antibiotic Treatment of Acinetobacter baumannii In Vivo.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 2, p. 273, doi. 10.3390/antibiotics11020273

By:

Schouten, Gina K.;
Paulussen, Felix M.;
Kuipers, Oscar P.;
Bitter, Wilbert;
Grossmann, Tom N.;
van Ulsen, Peter

Publication type:

Article

Reversible Covalent Inhibition of a Protein Target.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 35, p. 8699, doi. 10.1002/anie.201203341

By:

Lee, Chang-Uk;
Grossmann, Tom N.

Publication type:

Article

DNA-Triggered Synthesis and Bioactivity of Proapoptotic Peptides.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 12, p. 2828, doi. 10.1002/anie.201007103

By:

Erben, Anne;
Grossmann, Tom N.;
Seitz, Oliver

Publication type:

Article

Photo-Thermal Haptotropism in Cyclopentadienylcobalt Complexes of Linear Phenylenes: Intercyclobutadiene Metal Migration.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 52, p. 9853, doi. 10.1002/anie.200905088

By:

Albright, Thomas A.;
Dosa, Peter I.;
Grossmann, Tom N.;
Khrustalev, Victor N.;
Oloba, Oluwakemi A.;
Padilla, Robin;
Paubelle, Renaud;
Stanger, Amnon;
Timofeeva, Tatiana V.;
Vollhardt, K. Peter C.

Publication type:

Article

Target-Catalyzed Transfer Reactions for the Amplified Detection of RNA.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 37, p. 7119, doi. 10.1002/anie.200801355

By:

Grossmann, Tom N.;
Röglin, Lars;
Seitz, Oliver

Publication type:

Article

Triplex Molecular Beacons as Modular Probes for DNA Detection.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 27, p. 5223, doi. 10.1002/anie.200700289

By:

Grossmann, Tom N.;
Röglin, Lars;
Seitz, Oliver

Publication type:

Article

Environment‐Responsive Peptide Dimers Bind and Stabilize Double‐Stranded RNA.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 41, p. 1, doi. 10.1002/anie.202308028

By:

McLoughlin, Niall M.;
Albers, Marvin A.;
Collado Camps, Estel;
Paulus, Jannik;
Ran, Youri A.;
Neubacher, Saskia;
Hennig, Sven;
Brock, Roland;
Grossmann, Tom N.

Publication type:

Article

Back Cover: Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling (Angew. Chem. Int. Ed. 25/2021).

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 25, p. 14196, doi. 10.1002/anie.202104892

By:

Wendt, Mathias;
Bellavita, Rosa;
Gerber, Alan;
Efrém, Nina‐Louisa;
Ramshorst, Thirza;
Pearce, Nicholas M.;
Davey, Paul R. J.;
Everard, Isabel;
Vazquez‐Chantada, Mercedes;
Chiarparin, Elisabetta;
Grieco, Paolo;
Hennig, Sven;
Grossmann, Tom N.

Publication type:

Article

Bicyclic β‐Sheet Mimetics that Target the Transcriptional Coactivator β‐Catenin and Inhibit Wnt Signaling.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 25, p. 13937, doi. 10.1002/anie.202102082

By:

Wendt, Mathias;
Bellavita, Rosa;
Gerber, Alan;
Efrém, Nina‐Louisa;
Ramshorst, Thirza;
Pearce, Nicholas M.;
Davey, Paul R. J.;
Everard, Isabel;
Vazquez‐Chantada, Mercedes;
Chiarparin, Elisabetta;
Grieco, Paolo;
Hennig, Sven;
Grossmann, Tom N.

Publication type:

Article

Constrained Peptides with Fine‐Tuned Flexibility Inhibit NF‐Y Transcription Factor Assembly.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 48, p. 17351, doi. 10.1002/anie.201907901

By:

Jeganathan, Sadasivam;
Wendt, Mathias;
Kiehstaller, Sebastian;
Brancaccio, Diego;
Kuepper, Arne;
Pospiech, Nicole;
Carotenuto, Alfonso;
Novellino, Ettore;
Hennig, Sven;
Grossmann, Tom N.

Publication type:

Article

Inside Back Cover: Coiled‐Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection (Angew. Chem. Int. Ed. 52/2018).

Published in:

Angewandte Chemie International Edition, 2018, v. 57, n. 52, p. 17265, doi. 10.1002/anie.201813484

By:

Mueller, Carolin;
Grossmann, Tom N.

Publication type:

Article

Coiled‐Coil Peptide Beacon: A Tunable Conformational Switch for Protein Detection.

Published in:

Angewandte Chemie International Edition, 2018, v. 57, n. 52, p. 17079, doi. 10.1002/anie.201811515

By:

Mueller, Carolin;
Grossmann, Tom N.

Publication type:

Article

Structure‐Based Design of Bicyclic Helical Peptides That Target the Oncogene β‐Catenin.

Published in:

Angewandte Chemie, 2024, v. 136, n. 47, p. 1, doi. 10.1002/ange.202411749

By:

Yeste‐Vázquez, Alejandro;
Paulussen, Felix M.;
Wendt, Mathias;
Klintrot, Rasmus;
Schulte, Clemens;
Wallraven, Kerstin;
van Gijzel, Lieke;
Simeonov, Boris;
van der Gaag, Maurice;
Gerber, Alan;
Maric, Hans M.;
Hennig, Sven;
Grossmann, Tom N.

Publication type:

Article

Frontispiece: Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction.

Published in:

2018

By:

Schmidtgall, Boris;
Kuepper, Arne;
Meng, Melissa;
Grossmann, Tom N.;
Ducho, Christian

Publication type:

Image

Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 7, p. 1544, doi. 10.1002/chem.201704338

By:

Schmidtgall, Boris;
Kuepper, Arne;
Meng, Melissa;
Grossmann, Tom N.;
Ducho, Christian

Publication type:

Article

Increased Conformational Flexibility of a Macrocycle-Receptor Complex Contributes to Reduced Dissociation Rates.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 64, p. 16157, doi. 10.1002/chem.201702776

By:

Glas, Adrian;
Wamhoff, Eike‐Christian;
Krüger, Dennis M.;
Rademacher, Christoph;
Grossmann, Tom N.

Publication type:

Article

Cover Feature: Increased Conformational Flexibility of a Macrocycle-Receptor Complex Contributes to Reduced Dissociation Rates (Chem. Eur. J. 64/2017).

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 64, p. 16105, doi. 10.1002/chem.201704109

By:

Glas, Adrian;
Wamhoff, Eike‐Christian;
Krüger, Dennis M.;
Rademacher, Christoph;
Grossmann, Tom N.

Publication type:

Article

Chemical Biology 2012: From Drug Targets to Biological Systems and Back.

Published in:

ChemBioChem, 2013, v. 14, n. 1, p. 23, doi. 10.1002/cbic.201200697

By:

Socher, Elke;
Grossmann, Tom N.

Publication type:

Article

Achieving Turnover in DNA-Templated Reactions.

Published in:

ChemBioChem, 2008, v. 9, n. 14, p. 2185, doi. 10.1002/cbic.200800290

By:

Grossmann, Tom N.;
Strohbach, Anne;
Seitz, Oliver

Publication type:

Article

Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets.

Published in:

Nature Communications, 2017, v. 8, n. 3, p. 14690, doi. 10.1038/ncomms14690

By:

White, Mark D.;
Klecker, Maria;
Hopkinson, Richard J.;
Weits, Daan A.;
Mueller, Carolin;
Naumann, Christin;
O'Neill, Rebecca;
Wickens, James;
Yang, Jiayu;
Brooks-Bartlett, Jonathan C.;
Garman, Elspeth F.;
Grossmann, Tom N.;
Dissmeyer, Nico;
Flashman, Emily

Publication type:

Article

Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides.

Published in:

Nature Communications, 2016, v. 7, n. 4, p. 11300, doi. 10.1038/ncomms11300

By:

Cromm, Philipp M.;
Schaubach, Sebastian;
Spiegel, Jochen;
Fürstner, Alois;
Grossmann, Tom N.;
Waldmann, Herbert

Publication type:

Article

Neue Modalitäten für schwierige Zielstrukturen in der Wirkstoffentwicklung.

Published in:

Angewandte Chemie, 2017, v. 129, n. 35, p. 10428, doi. 10.1002/ange.201611914

By:

Valeur, Eric;
Guéret, Stéphanie M.;
Adihou, Hélène;
Gopalakrishnan, Ranganath;
Lemurell, Malin;
Waldmann, Herbert;
Grossmann, Tom N.;
Plowright, Alleyn T.

Publication type:

Article

Selective Protein Hyperpolarization in Cell Lysates Using Targeted Dynamic Nuclear Polarization.

Published in:

Angewandte Chemie, 2016, v. 128, n. 36, p. 10904, doi. 10.1002/ange.201603205

By:

Viennet, Thibault;
Viegas, Aldino;
Kuepper, Arne;
Arens, Sabine;
Gelev, Vladimir;
Petrov, Ognyan;
Grossmann, Tom N.;
Heise, Henrike;
Etzkorn, Manuel

Publication type:

Article

Innentitelbild: Selective Protein Hyperpolarization in Cell Lysates Using Targeted Dynamic Nuclear Polarization (Angew. Chem. 36/2016).

Published in:

Angewandte Chemie, 2016, v. 128, n. 36, p. 10682, doi. 10.1002/ange.201606093

By:

Viennet, Thibault;
Viegas, Aldino;
Kuepper, Arne;
Arens, Sabine;
Gelev, Vladimir;
Petrov, Ognyan;
Grossmann, Tom N.;
Heise, Henrike;
Etzkorn, Manuel

Publication type:

Article

Redox-Modulation der PTEN-Phosphataseaktivität durch Wasserstoffperoxid und Bisperoxidovanadium-Komplexe.

Published in:

Angewandte Chemie, 2015, v. 127, n. 46, p. 14001, doi. 10.1002/ange.201506338

By:

Lee, Chang ‐ Uk;
Hahne, Gernot;
Hanske, Jonas;
Bange, Tanja;
Bier, David;
Rademacher, Christoph;
Hennig, Sven;
Grossmann, Tom N.

Publication type:

Article

Direkte Modulation von Aktivität und Funktion kleiner GTPasen.

Published in:

Angewandte Chemie, 2015, v. 127, n. 46, p. 13718, doi. 10.1002/ange.201504357

By:

Cromm, Philipp M.;
Spiegel, Jochen;
Grossmann, Tom N.;
Waldmann, Herbert

Publication type:

Article

Strukturbasierte Entwicklung von Protein-Protein-Interaktionsinhibitoren: Stabilisierung und Nachahmung von Peptidliganden.

Published in:

Angewandte Chemie, 2015, v. 127, n. 31, p. 9022, doi. 10.1002/ange.201412070

By:

Pelay-Gimeno, Marta;
Glas, Adrian;
Koch, Oliver;
Grossmann, Tom N.

Publication type:

Article

Protein-vermittelte Peptidverknüpfung.

Published in:

Angewandte Chemie, 2014, v. 126, n. 17, p. 4425, doi. 10.1002/ange.201400681

By:

Brauckhoff, Nicolas;
Hahne, Gernot;
Yeh, Johannes T. ‐ H.;
Grossmann, Tom N.

Publication type:

Article

Rücktitelbild: Makrocyclische Peptide mit dem Zielprotein angepassten Kohlenwasserstoffbrücken: Inhibitoren einer pathogenen Protein-Protein-Wechselwirkung (Angew. Chem. 9/2014).

Published in:

Angewandte Chemie, 2014, v. 126, n. 9, p. 2544, doi. 10.1002/ange.201400778

By:

Glas, Adrian;
Bier, David;
Hahne, Gernot;
Rademacher, Christoph;
Ottmann, Christian;
Grossmann, Tom N.

Publication type:

Article

Makrocyclische Peptide mit dem Zielprotein angepassten Kohlenwasserstoffbrücken: Inhibitoren einer pathogenen Protein-Protein-Wechselwirkung.

Published in:

Angewandte Chemie, 2014, v. 126, n. 9, p. 2522, doi. 10.1002/ange.201310082

By:

Glas, Adrian;
Bier, David;
Hahne, Gernot;
Rademacher, Christoph;
Ottmann, Christian;
Grossmann, Tom N.

Publication type:

Article

Direkte Modulation von Rab-GTPase-Effektor-Wechselwirkungen.

Published in:

Angewandte Chemie, 2014, v. 126, n. 9, p. 2531, doi. 10.1002/ange.201308568

By:

Spiegel, Jochen;
Cromm, Philipp M.;
Itzen, Aymelt;
Goody, Roger S.;
Grossmann, Tom N.;
Waldmann, Herbert

Publication type:

Article