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Suppression of metastasis formation by a recombinant single chain antibody-toxin targeted to full-length and oncogenic variant EGF receptors.
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- Oncogene, 1999, v. 18, n. 9, p. 1711, doi. 10.1038/sj.onc.1202489
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- Article
Tumors caused by overexpression and forced activation of Stat5 in mammary epithelial cells of transgenic mice are parity-dependent and developed in aged, postestropausal females.
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- International Journal of Cancer, 2007, v. 121, n. 9, p. 1892, doi. 10.1002/ijc.22954
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- Article
Deregulation of Stat5 expression and activation causes mammary tumors in transgenic mice.
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- International Journal of Cancer, 2004, v. 112, n. 4, p. 607, doi. 10.1002/ijc.20484
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- Article
Recombinant antibody toxins specific for ErbB2 and EGF receptor inhibit the in vitro growth of human head and neck cancer cells and cause rapid tumor regression in vivo.
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- International Journal of Cancer, 2000, v. 86, n. 2, p. 269, doi. 10.1002/(SICI)1097-0215(20000415)86:2<269::AID-IJC18>3.0.CO;2-8
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Protection against mammary tumor growth by vaccination with full-length, modified human ErbB-2 DNA.
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- International Journal of Cancer, 1999, v. 81, n. 5, p. 748, doi. 10.1002/(SICI)1097-0215(19990531)81:5<748::AID-IJC14>3.0.CO;2-6
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Targeted therapy of Schwannoma cells in immunocompetent rats with an erbB2-specific antibody-toxin.
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- International Journal of Cancer, 1997, v. 73, n. 1, p. 117, doi. 10.1002/(SICI)1097-0215(19970926)73:1<117::AID-IJC18>3.0.CO;2-D
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- Article
Intra-tumoral application of a heregulin-exotoxin-A fusion protein causes rapid tumor regression without adverse systemic or local effects.
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- International Journal of Cancer, 1997, v. 70, n. 6, p. 682, doi. 10.1002/(SICI)1097-0215(19970317)70:6<682::AID-IJC10>3.0.CO;2-C
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- Article
Schannoma cells induce a tumor-cell-specific cytotoxic- T-cell response upon transplantation into syngeneic rats but escape elimination through the secretion of immunosuppressive factors.
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- International Journal of Cancer, 1997, v. 70, n. 5, p. 542, doi. 10.1002/(SICI)1097-0215(19970304)70:5<542::AID-IJC9>3.0.CO;2-Y
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- Article
Growth retardation of tumors by adoptive transfer of cytotoxic T lymphocytes reprogrammed by CD44V6-specific SCFV: ζ-chimera.
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- International Journal of Cancer, 1996, v. 68, n. 2, p. 232, doi. 10.1002/(SICI)1097-0215(19961009)68:2<232::AID-IJC16>3.0.CO;2-C
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- Article
A bivalent single-chain antibody-toxin specific for ErbB-2 and the EGF receptor.
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- International Journal of Cancer, 1996, v. 65, n. 4, p. 538, doi. 10.1002/(SICI)1097-0215(19960208)65:4<538::AID-IJC24>3.0.CO;2-4
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- Article
Targeted inhibition of tumor-cell growth by recombinant heregulin-toxin fusion proteins.
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- International Journal of Cancer, 1995, v. 60, n. 5, p. 730, doi. 10.1002/ijc.2910600527
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- Article
EGF receptor and p185.
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- International Journal of Cancer, 1995, v. 60, n. 1, p. 137, doi. 10.1002/ijc.2910600120
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Chapter III. 1. Mutations in human breast cancer cells: Dominantly-acting oncogenes and tumor suppressor genes suggest strategies for targeted interference.
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- International Journal of Cancer, 1990, v. 46, p. 40, doi. 10.1002/ijc.2910460705
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- Article
miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development.
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- Nature Genetics, 2010, v. 42, n. 12, p. 1101, doi. 10.1038/ng.709
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- Article
Expression of a carboxy terminally truncated Stat5 with no transactivation domain in the mammary glands of transgenic mice inhibits cell proliferation during pregnancy, delays onset of milk secretion, and induces apoptosis upon involution.
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- Molecular Reproduction & Development, 2006, v. 73, n. 7, p. 841, doi. 10.1002/mrd.20479
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- Article
Adaptive resistance to immunotherapy directed against p53 can be overcome by global expression of tumor-antigens in dendritic cells.
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- Frontiers in Oncology, 2014, v. 4, p. 1, doi. 10.3389/fonc.2014.00270
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- Article
FOXA1 mutations in hormone-dependent cancers.
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- Frontiers in Oncology, 2013, v. 3, p. 1, doi. 10.3389/fonc.2013.00020
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Targeting Survivin in Cancer: Novel Drug Development Approaches.
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- BioDrugs, 2014, v. 28, n. 1, p. 27, doi. 10.1007/s40259-013-0058-x
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- Article
Murine amniotic fluid stem cells contribute mesenchymal but not epithelial components to reconstituted mammary ducts.
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- Stem Cell Research & Therapy, 2010, v. 1, n. 3, p. 1, doi. 10.1186/scrt20
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- Article
Oncogene expression in mammary epithelial cells.
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- Journal of Cellular Biochemistry, 1992, v. 49, n. 2, p. 128, doi. 10.1002/jcb.240490205
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- Article
Overexpression of the c-erbB-2 protein in human breast tumor cell lines.
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- Journal of Cellular Biochemistry, 1989, v. 39, n. 2, p. 167, doi. 10.1002/jcb.240390208
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- Article
Mammary Epithelial Reconstitution with Gene-Modified Stem Cells Assigns Roles to Stat5 in Luminal Alveolar Cell Fate Decisions, Differentiation, Involution, and Mammary Tumor Formation.
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- Stem Cells, 2010, v. 28, n. 5, p. 928, doi. 10.1002/stem.407
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Comparison of the nuclear proteomes of mammary epithelial cells at different stages of functional differentiation.
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- Proteomics, 2007, v. 7, n. 12, p. 2019, doi. 10.1002/pmic.200600994
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- Article
The histone deacetylases HDAC1 and HDAC2 are required for the growth and survival of renal carcinoma cells.
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- Archives of Toxicology, 2018, v. 92, n. 7, p. 2227, doi. 10.1007/s00204-018-2229-5
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Peptide Drug Discovery and Development: Translational Research in Academia and Industry. Edited by Miguel Castanho and Nuno C. Santos.
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- ChemMedChem, 2012, v. 7, n. 6, p. 1123, doi. 10.1002/cmdc.201200178
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- Article
Survivin inhibition by an interacting recombinant peptide, derived from the human ferritin heavy chain, impedes tumor cell growth.
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- Journal of Cancer Research & Clinical Oncology, 2012, v. 138, n. 7, p. 1205, doi. 10.1007/s00432-012-1195-1
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DNA vaccination with a mutated p53 allele induces specific cytolytic T cells and protects against tumor cell growth and the formation of metastasis.
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- Journal of Cancer Research & Clinical Oncology, 2009, v. 135, n. 4, p. 567, doi. 10.1007/s00432-008-0491-2
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- Article
Bifunctional recombinant proteins in cancer therapy: cell penetrating peptide aptamers as inhibitors of growth factor signaling.
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- Journal of Cancer Research & Clinical Oncology, 2003, v. 129, n. 12, p. 669, doi. 10.1007/s00432-003-0489-8
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- Article
Three-dimensional structure of the STAT3Beta homodimer bound to DNA.
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- Nature, 1998, v. 394, n. 6689, p. 145, doi. 10.1038/28101
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Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine.
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- Journal of Innate Immunity, 2016, v. 8, n. 2, p. 111, doi. 10.1159/000443526
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- Article
STAT3 Induction of miR-146b Forms a Feedback Loop to Inhibit the NF-κB to IL-6 Signaling Axis and STAT3-Driven Cancer Phenotypes.
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- Science Signaling, 2014, v. 7, n. 310, p. 1, doi. 10.1126/scisignal.2004497
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p300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6.
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- Nucleic Acids Research, 1999, v. 27, n. 13, p. 2722, doi. 10.1093/nar/27.13.2722
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Current strategies for the development of peptide-based anti-cancer therapeutics.
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- Journal of Peptide Science, 2005, v. 11, n. 11, p. 713, doi. 10.1002/psc.717
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Stat5 Exerts Distinct, Vital Functions in the Cytoplasm and Nucleus of Bcr-Abl<sup>+</sup> K562 and Jak2(V617F)<sup>+</sup> HEL Leukemia Cells.
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- Cancers, 2015, v. 7, n. 1, p. 503, doi. 10.3390/cancers7010503
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Mammary gland biology and breast cancer. Conference on Common Molecular Mechanisms of Mammary Gland Development and Breast Cancer Progression.
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- EMBO Reports, 2006, v. 7, n. 11, p. 1084, doi. 10.1038/sj.embor.7400839
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- Article
Protein interactions at the carboxyl terminus of p53 result in the induction of its in vitro transactivation potential.
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- Oncogene, 1997, v. 15, n. 2, p. 237, doi. 10.1038/sj.onc.1201174
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- Article
Expression of reprogramming factors in breast cancer cell lines and the regulation by activated Stat3.
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- Hormone Molecular Biology & Clinical Investigation, 2012, v. 10, n. 2, p. 241, doi. 10.1515/hmbci-2012-0003
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- Article
Inhibition of Stat3 by peptide aptamer rS3-PA enhances growth suppressive effects of irinotecan on colorectal cancer cells.
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- Hormone Molecular Biology & Clinical Investigation, 2012, v. 10, n. 2, p. 273, doi. 10.1515/hmbci-2012-0014
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- Article
Stat3 inhibition in neural lineage cells.
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- Hormone Molecular Biology & Clinical Investigation, 2012, v. 10, n. 2, p. 255, doi. 10.1515/hmbci-2012-0005
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- Article
Stat3 is activated in skin lesions by the local application of imiquimod, a ligand of TLR7, and inhibited by the recombinant peptide aptamer rS3-PA.
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- Hormone Molecular Biology & Clinical Investigation, 2012, v. 10, n. 2, p. 265, doi. 10.1515/hmbci-2012-0007
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- Article
The versatile regulation of cellular events by Jak-Stat signaling: from transcriptional control to microtubule dynamics and energy metabolism.
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- Hormone Molecular Biology & Clinical Investigation, 2012, v. 10, n. 1, p. 193, doi. 10.1515/hmbci-2012-0010
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- Article
Transforming growth factor β signaling regulates the invasiveness of normal mammary epithelial cells and the metastasis formation of tumor cells.
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- Hormone Molecular Biology & Clinical Investigation, 2012, v. 10, n. 1, p. 227, doi. 10.1515/hmbci-2012-0016
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- Article
Cytokine receptors and their Stat-mediated mechanisms of action.
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- Hormone Molecular Biology & Clinical Investigation, 2012, v. 10, n. 1, p. 191, doi. 10.1515/hmbci-2012-0017
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- Article
The integration of a Stat3 specific peptide aptamer into the thioredoxin scaffold protein strongly enhances its inhibitory potency.
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- Hormone Molecular Biology & Clinical Investigation, 2011, v. 5, n. 1, p. 1, doi. 10.1515/HMBCI.2011.013
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- Article
Visualization of Stat3 and Stat5 transactivation activity with specific response element dependent reporter constructs integrated into lentiviral gene transfer vectors.
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- Hormone Molecular Biology & Clinical Investigation, 2010, v. 1, n. 3, p. 127, doi. 10.1515/HMBCI.2010.017
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- Article
Breast Cancer Patients Have Greatly Benefited from the Progress in Molecular Oncology.
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- PLoS Biology, 2016, v. 14, n. 9, p. 1, doi. 10.1371/journal.pbio.2000314
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Delimitation of a DNA sequence which confers inducibility by glucocorticoid hormones.
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- Journal of Cellular Biochemistry, 1982, v. 20, n. 4, p. 349, doi. 10.1002/jcb.240200405
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- Article
STAT3 silencing inhibits glioma single cell infiltration and tumor growth.
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- Neuro-Oncology, 2013, v. 15, n. 7, p. 840, doi. 10.1093/neuonc/not025
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Expression of the mi R-302/367 cluster in glioblastoma cells suppresses tumorigenic gene expression patterns and abolishes transformation related phenotypes.
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- International Journal of Cancer, 2015, v. 137, n. 10, p. 2296, doi. 10.1002/ijc.29606
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- Article
The Inhibition of Stat5 by a Peptide Aptamer Ligand Specific for the DNA Binding Domain Prevents Target Gene Transactivation and the Growth of Breast and Prostate Tumor Cells.
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- Pharmaceuticals (14248247), 2013, v. 6, n. 8, p. 960, doi. 10.3390/ph6080960
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- Article