Works by Groll, Michael

Results: 127

Erosive Wind Characteristics and Aeolian Sediment Transport and Dune Formation in Makran Region of Baluchistan, Iran.

Published in:

Atmosphere, 2025, v. 16, n. 6, p. 650, doi. 10.3390/atmos16060650

By:

Abbasi, Hamidreza;
Gohardoust, Azadeh;
Mohammadpour, Fazeh;
Khosroshahi, Mohammad;
Groll, Michael;
Opp, Christian

Publication type:

Article

Rationales Design eines Proteasominhibitors als Anti-Malaria-Wirkstoff.

Published in:

Angewandte Chemie, 2016, v. 128, n. 22, p. 6478, doi. 10.1002/ange.201602519

By:

Le Chapelain, Camille;
Groll, Michael

Publication type:

Article

Struktur der Dioxygenase AsqJ: mechanistische Einblicke in die Eintopf-Mehrstufen-Biosynthese eines Chinolonantibiotikums.

Published in:

Angewandte Chemie, 2016, v. 128, n. 1, p. 432, doi. 10.1002/ange.201507835

By:

Bräuer, Alois;
Beck, Philipp;
Hintermann, Lukas;
Groll, Michael

Publication type:

Article

Reversible Inhibitoren arretieren ClpP in einer definierten Konformation, die durch Bindung von ClpX aufgehoben wird.

Published in:

Angewandte Chemie, 2015, v. 127, n. 52, p. 16121, doi. 10.1002/ange.201507266

By:

Pahl, Axel;
Lakemeyer, Markus;
Vielberg, Marie ‐ Theres;
Hackl, Mathias W.;
Vomacka, Jan;
Korotkov, Vadim S.;
Stein, Martin L.;
Fetzer, Christian;
Lorenz ‐ Baath, Katrin;
Richter, Klaus;
Waldmann, Herbert;
Groll, Michael;
Sieber, Stephan A.

Publication type:

Article

Selektive Hemmung des Immunproteasoms durch strukturbasierte Wahl eines nichtkatalytischen Cysteins als Angriffspunkt.

Published in:

Angewandte Chemie, 2015, v. 127, n. 52, p. 16116, doi. 10.1002/ange.201506631

By:

Dubiella, Christian;
Baur, Regina;
Cui, Haissi;
Huber, Eva M.;
Groll, Michael

Publication type:

Article

Identifizierung eines Sulfonamids als β1/β2-spezifischer Proteasomligand durch kristallographisches Screening.

Published in:

Angewandte Chemie, 2015, v. 127, n. 38, p. 11428, doi. 10.1002/ange.201505054

By:

Beck, Philipp;
Reboud ‐ Ravaux, Michèle;
Groll, Michael

Publication type:

Article

Ein minimales β-Lacton-Gerüst für selektive β5c- oder β5i-Proteasominhibitoren.

Published in:

Angewandte Chemie, 2015, v. 127, n. 27, p. 7921, doi. 10.1002/ange.201502931

By:

Groll, Michael;
Korotkov, Vadim S.;
Huber, Eva M.;
de Meijere, Armin;
Ludwig, Antje

Publication type:

Article

Struktur und Mechanismus des Heterokomplexes der caseinolytischen Protease ClpP1/2 aus Listeria monocytogenes.

Published in:

Angewandte Chemie, 2015, v. 127, n. 12, p. 3668, doi. 10.1002/ange.201409325

By:

Dahmen, Maria;
Vielberg, Marie-Theres;
Groll, Michael;
Sieber, Stephan A.

Publication type:

Article

Indolo-Phakelline als β5-spezifische nichtkovalente Proteasom-Inhibitoren.

Published in:

Angewandte Chemie, 2015, v. 127, n. 9, p. 2872, doi. 10.1002/ange.201410168

By:

Beck, Philipp;
Lansdell, Theresa A.;
Hewlett, Nicole M.;
Tepe, Jetze J.;
Groll, Michael

Publication type:

Article

Selektive Inhibition des Immunoproteasoms durch ligandeninduzierte Vernetzung des katalytischen Zentrums.

Published in:

Angewandte Chemie, 2014, v. 126, n. 44, p. 12163, doi. 10.1002/ange.201406964

By:

Dubiella, Christian;
Cui, Haissi;
Gersch, Malte;
Brouwer, Arwin J.;
Sieber, Stephan A.;
Krüger, Achim;
Liskamp, Rob M. J.;
Groll, Michael

Publication type:

Article

Pyrrolysin-Synthase (PylD) katalysiert die Bildung von Pyrrolin- und Tetrahydropyridinringen in Aminosäuren.

Published in:

Angewandte Chemie, 2014, v. 126, n. 31, p. 8289, doi. 10.1002/ange.201402595

By:

Quitterer, Felix;
Beck, Philipp;
Bacher, Adelbert;
Groll, Michael

Publication type:

Article

Substratinduzierte Konformationsänderungen in Klasse-I-Terpencyclasen.

Published in:

Angewandte Chemie, 2014, v. 126, n. 29, p. 7783, doi. 10.1002/ange.201403648

By:

Baer, Philipp;
Rabe, Patrick;
Fischer, Katrin;
Citron, Christian A.;
Klapschinski, Tim A.;
Groll, Michael;
Dickschat, Jeroen S.

Publication type:

Article

Analyse von Protease-Inhibitor-Interaktionen unter Nutzung evolvierbarer tricyclischer Microviridine.

Published in:

Angewandte Chemie, 2014, v. 126, n. 14, p. 3810, doi. 10.1002/ange.201309721

By:

Weiz, Annika R.;
Ishida, Keishi;
Quitterer, Felix;
Meyer, Sabine;
Kehr, Jan ‐ Christoph;
Müller, Kristian M.;
Groll, Michael;
Hertweck, Christian;
Dittmann, Elke

Publication type:

Article

Pseudiline: halogenierte, allosterische Inhibitoren des Enzyms IspD aus dem Mevalonat‐unabhängigen Biosyntheseweg.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2267, doi. 10.1002/ange.201309557

By:

Kunfermann, Andrea;
Witschel, Matthias;
Illarionov, Boris;
Martin, René;
Rottmann, Matthias;
Höffken, H. Wolfgang;
Seet, Michael;
Eisenreich, Wolfgang;
Knölker, Hans‐Joachim;
Fischer, Markus;
Bacher, Adelbert;
Groll, Michael;
Diederich, François

Publication type:

Article

Flavoenzym‐katalysierte Bildung von Disulfidbrücken in Naturstoffen.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2253, doi. 10.1002/ange.201309302

By:

Scharf, Daniel H.;
Groll, Michael;
Habel, Andreas;
Heinekamp, Thorsten;
Hertweck, Christian;
Brakhage, Axel A.;
Huber, Eva M.

Publication type:

Article

Flavoenzym-katalysierte Bildung von Disulfidbrücken in Naturstoffen.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2253, doi. 10.1002/ange.201309302

By:

Scharf, Daniel H.;
Groll, Michael;
Habel, Andreas;
Heinekamp, Thorsten;
Hertweck, Christian;
Brakhage, Axel A.;
Huber, Eva M.

Publication type:

Article

Pseudiline: halogenierte, allosterische Inhibitoren des Enzyms IspD aus dem Mevalonat-unabhängigen Biosyntheseweg.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2267, doi. 10.1002/ange.201309557

By:

Kunfermann, Andrea;
Witschel, Matthias;
Illarionov, Boris;
Martin, René;
Rottmann, Matthias;
Höffken, H. Wolfgang;
Seet, Michael;
Eisenreich, Wolfgang;
Knölker, Hans ‐ Joachim;
Fischer, Markus;
Bacher, Adelbert;
Groll, Michael;
Diederich, François

Publication type:

Article

Ein systematischer Vergleich peptidischer Proteasominhibitoren unterstreicht α-Ketoamid als vielversprechende elektrophile Leitstruktur.

Published in:

Angewandte Chemie, 2014, v. 126, n. 6, p. 1705, doi. 10.1002/ange.201308984

By:

Stein, Martin L.;
Cui, Haissi;
Beck, Philipp;
Dubiella, Christian;
Voss, Constantin;
Krüger, Achim;
Schmidt, Boris;
Groll, Michael

Publication type:

Article

Omuralid und Vibralacton: Unterschiede im Proteasom-β-Lacton-γ-Lactamgerüst verändern die Zielmolekülpräferenz.

Published in:

Angewandte Chemie, 2014, v. 126, n. 2, p. 582, doi. 10.1002/ange.201308567

By:

List, Anja;
Zeiler, Evelyn;
Gallastegui, Nerea;
Rusch, Marion;
Hedberg, Christian;
Sieber, Stephan A.;
Groll, Michael

Publication type:

Article

Struktur und Reaktionsmechanismus der Pyrrolysinsynthase (PylD).

Published in:

Angewandte Chemie, 2013, v. 125, n. 27, p. 7171, doi. 10.1002/ange.201301164

By:

Quitterer, Felix;
Beck, Philipp;
Bacher, Adelbert;
Groll, Michael

Publication type:

Article

Fluor-, Amino- und Thiolinhibitoren im Komplex mit dem [Fe<sub>4</sub>S<sub>4</sub>]-Protein IspH.

Published in:

Angewandte Chemie, 2013, v. 125, n. 7, p. 2172, doi. 10.1002/ange.201208469

By:

Span, Ingrid;
Wang, Ke;
Wang, Weixue;
Jauch, Johann;
Eisenreich, Wolfgang;
Bacher, Adelbert;
Oldfield, Eric;
Groll, Michael

Publication type:

Article

Inhibitoren für das konstitutive Proteasom und das Immunoproteasom: aktuelle und zukünftige Tendenzen in der Medikamentenentwicklung.

Published in:

Angewandte Chemie, 2012, v. 124, n. 35, p. 8838, doi. 10.1002/ange.201201616

By:

Huber, Eva Maria;
Groll, Michael

Publication type:

Article

Titelbild: Kristallstruktur der Methylornithin-Synthase (PylB): Einblicke in die Biosynthese von Pyrrolysin (Angew. Chem. 6/2012).

Published in:

Angewandte Chemie, 2012, v. 124, n. 6, p. 1309, doi. 10.1002/ange.201107547

By:

Quitterer, Felix;
List, Anja;
Eisenreich, Wolfgang;
Bacher, Adelbert;
Groll, Michael

Publication type:

Article

Kristallstruktur der Methylornithin-Synthase (PylB): Einblicke in die Biosynthese von Pyrrolysin.

Published in:

Angewandte Chemie, 2012, v. 124, n. 6, p. 1367, doi. 10.1002/ange.201106765

By:

Quitterer, Felix;
List, Anja;
Eisenreich, Wolfgang;
Bacher, Adelbert;
Groll, Michael

Publication type:

Article

Hydroxyharnstoffe als nichtkovalente Proteasom-Inhibitoren.

Published in:

Angewandte Chemie, 2012, v. 124, n. 1, p. 251, doi. 10.1002/ange.201106010

By:

Gallastegui, Nerea;
Beck, Philipp;
Arciniega, Marcelino;
Huber, Robert;
Hillebrand, Stefan;
Groll, Michael

Publication type:

Article

α-Keto-Aldehyd-Peptide: ein Leitmotiv für die Entwicklung reversibler Proteasominhibitoren.

Published in:

Angewandte Chemie, 2011, v. 123, n. 2, p. 563, doi. 10.1002/ange.201005488

By:

Gräwert, Melissa Ann;
Gallastegui, Nerea;
Stein, Martin;
Schmidt, Boris;
Kloetzel, Peter-Michael;
Huber, Robert;
Groll, Michael

Publication type:

Article

PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72.

Published in:

Biochemical Journal, 2020, v. 477, n. 9, p. 1651, doi. 10.1042/BCJ20190664

By:

Vieweg, Sophie;
Mulholland, Katie;
Bräuning, Bastian;
Kachariya, Nitin;
Yu-Chiang Lai;
Toth, Rachel;
Singh, Pawan Kishor;
Volpi, Ilaria;
Sattler, Michael;
Groll, Michael;
Itzen, Aymelt;
Muqit, Miratul M. K.

Publication type:

Article

Polyketide Trimming Shapes Dihydroxynaphthalene‐Melanin and Anthraquinone Pigments.

Published in:

Advanced Science, 2024, v. 11, n. 22, p. 1, doi. 10.1002/advs.202400184

By:

Schmalhofer, Maximilian;
Vagstad, Anna L.;
Zhou, Qiuqin;
Bode, Helge B.;
Groll, Michael

Publication type:

Article

Structure of Active IspH Enzyme from Escherichia coli Provides Mechanistic Insights into Substrate Reduction.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 31, p. 5756, doi. 10.1002/anie.200900548

By:

Gräwert, Tobias;
Rohdich, Felix;
Span, Ingrid;
Bacher, Adelbert;
Eisenreich, Wolfgang;
Eppinger, Jörg;
Groll, Michael

Publication type:

Article

Gonadotropic patterns in psychogenic amenorrhea.

Published in:

1978

By:

Groll, Michael;
Groll, M

Publication type:

journal article

The persisting challenge of selective and specific proteasome inhibition.

Published in:

Journal of Peptide Science, 2009, v. 15, n. 2, p. 58, doi. 10.1002/psc.1107

By:

Groll, Michael;
Huber, Robert;
Moroder, Luis

Publication type:

Article

Mapping of Major Land-Use Changes in the Kolleru Lake Freshwater Ecosystem by Using Landsat Satellite Images in Google Earth Engine.

Published in:

Water (20734441), 2020, v. 12, n. 9, p. 2493, doi. 10.3390/w12092493

By:

Kolli, Meena Kumari;
Opp, Christian;
Karthe, Daniel;
Groll, Michael

Publication type:

Article

System Dynamics Modeling of Water Level Variations of Lake Issyk-Kul, Kyrgyzstan.

Published in:

Water (20734441), 2017, v. 9, n. 12, p. 989, doi. 10.3390/w9120989

By:

Yilinuer Alifujiang;
Abuduwaili, Jilili;
Long Ma;
Samat, Alim;
Groll, Michael

Publication type:

Article

Structural and Mechanistic Features of ClyA-Like α-Pore-Forming Toxins.

Published in:

Toxins, 2018, v. 10, n. 9, p. 343, doi. 10.3390/toxins10090343

By:

Bräuning, Bastian;
Groll, Michael

Publication type:

Article

Receptor-Bound Conformation of Cilengitide Better Represented by Its Solution-State Structure than the Solid-State Structure.

Published in:

Chemistry - A European Journal, 2014, v. 20, n. 44, p. 14201, doi. 10.1002/chem.201403839

By:

Marelli, Udaya Kiran;
Frank, Andreas O.;
Wahl, Bernhard;
La Pietra, Valeria;
Novellino, Ettore;
Marinelli, Luciana;
Herdtweck, Eberhardt;
Groll, Michael;
Kessler, Horst

Publication type:

Article

Immunoproteasom: drug development for xenotransplantation.

Published in:

Xenotransplantation, 2013, v. 20, n. 1, p. 57, doi. 10.1111/xen.12014_14

By:

Groll, Michael

Publication type:

Article

Immunoproteasome: Drug development for xenotransplantation.

Published in:

Xenotransplantation, 2012, v. 19, n. 1, p. 20, doi. 10.1111/j.1399-3089.2011.00680_15.x

By:

Groll, Michael

Publication type:

Article

Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37621-7

By:

Kaspers, Marietta S.;
Pogenberg, Vivian;
Pett, Christian;
Ernst, Stefan;
Ecker, Felix;
Ochtrop, Philipp;
Groll, Michael;
Hedberg, Christian;
Itzen, Aymelt

Publication type:

Article

Isofunctional but Structurally Different Methyltransferases for Dithiolopyrrolone Diversification.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 49, p. 1, doi. 10.1002/anie.202410799

By:

Su, Li;
Huber, Eva M.;
Westphalen, Margaretha;
Gellner, Jonas;
Bode, Edna;
Köbel, Tania;
Grün, Peter;
Alanjary, Mohammad M.;
Glatter, Timo;
Cirnski, Katarina;
Müller, Rolf;
Schindler, Daniel;
Groll, Michael;
Bode, Helge B.

Publication type:

Article

Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 8, p. 1, doi. 10.1002/anie.202314791

By:

Morstein, Johannes;
Amatuni, Alexander;
Shuster, Anton;
Kuttenlochner, Wolfgang;
Ko, Tongil;
Abegg, Daniel;
Groll, Michael;
Adibekian, Alexander;
Renata, Hans;
Trauner, Dirk H.

Publication type:

Article

Structure of Staphylococcus aureus ClpP Bound to the Covalent Active‐Site Inhibitor Cystargolide A.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 3, p. 1, doi. 10.1002/anie.202314028

By:

Illigmann, Astrid;
Vielberg, Marie‐Theres;
Lakemeyer, Markus;
Wolf, Felix;
Dema, Taulant;
Stange, Patrik;
Kuttenlochner, Wolfgang;
Liebhart, Elisa;
Kulik, Andreas;
Staudt, Nicole D.;
Malik, Imran;
Grond, Stephanie;
Sieber, Stephan A.;
Kaysser, Leonard;
Groll, Michael;
Brötz‐Oesterhelt, Heike

Publication type:

Article

A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 31, p. 1, doi. 10.1002/anie.202304533

By:

Dienemann, Jan‐Niklas;
Chen, Shu‐Yu;
Hitzenberger, Manuel;
Sievert, Montana L.;
Hacker, Stephan M.;
Prigge, Sean T.;
Zacharias, Martin;
Groll, Michael;
Sieber, Stephan A.

Publication type:

Article

A Specialized Polythioamide‐Binding Protein Confers Antibiotic Self‐Resistance in Anaerobic Bacteria.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 37, p. 1, doi. 10.1002/anie.202206168

By:

Gude, Finn;
Molloy, Evelyn M.;
Horch, Therese;
Dell, Maria;
Dunbar, Kyle L.;
Krabbe, Jana;
Groll, Michael;
Hertweck, Christian

Publication type:

Article

Crystal Structure and Active Site Engineering of a Halophilic γ-Carbonic Anhydrase.

Published in:

Frontiers in Microbiology, 2020, v. 11, p. 1, doi. 10.3389/fmicb.2020.00742

By:

Vogler, Malvina;
Karan, Ram;
Renn, Dominik;
Vancea, Alexandra;
Vielberg, Marie-Theres;
Grötzinger, Stefan W.;
DasSarma, Priya;
DasSarma, Shiladitya;
Eppinger, Jörg;
Groll, Michael;
Rueping, Magnus

Publication type:

Article

Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04139-2

By:

Bräuning, Bastian;
Bertosin, Eva;
Praetorius, Florian;
Ihling, Christian;
Schatt, Alexandra;
Adler, Agnes;
Richter, Klaus;
Sinz, Andrea;
Dietz, Hendrik;
Groll, Michael

Publication type:

Article

Catalytic mechanism and molecular engineering of quinolone biosynthesis in dioxygenase AsqJ.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03442-2

By:

Mader, Sophie L.;
Bräuer, Alois;
Groll, Michael;
Kaila, Ville R. I.

Publication type:

Article

The protease GtgE from Salmonella exclusively targets inactive Rab GTPases.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02110-1

By:

Wachtel, Rudolf;
Bräuning, Bastian;
Mader, Sophie L.;
Ecker, Felix;
Kaila, Ville R. I.;
Groll, Michael;
Itzen, Aymelt

Publication type:

Article

Estimation of soil erosion and sediment yield concentration across the Kolleru Lake catchment using GIS.

Published in:

Environmental Earth Sciences, 2021, v. 80, n. 4, p. 1, doi. 10.1007/s12665-021-09443-7

By:

Kolli, Meena Kumari;
Opp, Christian;
Groll, Michael

Publication type:

Article

TMC-95A Analogues with Endocyclic Biphenyl Ether Group as Proteasome Inhibitors.

Published in:

Chemistry & Biodiversity, 2004, v. 1, n. 1, p. 161, doi. 10.1002/cbdv.200490008

By:

Kaiser, Markus;
Milbradt, Alexander G.;
Siciliano, Carlo;
Assfalg-Machleidt, Irmgard;
Machleidt, Werner;
Groll, Michael;
Renner, Christian;
Moroder, Luis

Publication type:

Article

Molecular Machines for Protein Degradation.

Published in:

ChemBioChem, 2005, v. 6, n. 2, p. 222, doi. 10.1002/cbic.200400313

By:

Michael Groll;
Matthias Bochtler;
Hans Brandstetter;
Tim Clausen;
Robert Huber

Publication type:

Article