Works by Grogan, Gideon

Results: 79

Comparing the Catalytic and Structural Characteristics of a 'Short' Unspecific Peroxygenase (UPO) Expressed in Pichia pastoris and Escherichia coli.

Published in:

ChemBioChem, 2023, v. 24, n. 1, p. 1, doi. 10.1002/cbic.202200558

By:

Robinson, Wendy X. Q.;
Mielke, Tamara;
Melling, Benjamin;
Cuetos, Anibal;
Parkin, Alison;
Unsworth, William P.;
Cartwright, Jared;
Grogan, Gideon

Publication type:

Article

Advanced Insights into Catalytic and Structural Features of the Zinc‐Dependent Alcohol Dehydrogenase from Thauera aromatica.

Published in:

ChemBioChem, 2022, v. 23, n. 15, p. 1, doi. 10.1002/cbic.202200149

By:

Stark, Frances;
Loderer, Christoph;
Petchey, Mark;
Grogan, Gideon;
Ansorge‐Schumacher, Marion B.

Publication type:

Article

Structure and Mutation of the Native Amine Dehydrogenase MATOUAmDH2.

Published in:

ChemBioChem, 2022, v. 23, n. 10, p. 1, doi. 10.1002/cbic.202200136

By:

Bennett, Megan;
Ducrot, Laurine;
Vergne‐Vaxelaire, Carine;
Grogan, Gideon

Publication type:

Article

An Aminocaprolactam Racemase from Ochrobactrum anthropi with Promiscuous Amino Acid Ester Racemase Activity.

Published in:

ChemBioChem, 2018, v. 19, n. 16, p. 1711, doi. 10.1002/cbic.201800265

By:

Frese, Amina;
Barrass, Sarah V.;
Sutton, Peter W.;
Adams, Joe P.;
Grogan, Gideon

Publication type:

Article

Structural Basis for Phospholyase Activity of a Class III Transaminase Homologue.

Published in:

ChemBioChem, 2016, v. 17, n. 24, p. 2308, doi. 10.1002/cbic.201600482

By:

Cuetos, Anibal;
Steffen‐Munsberg, Fabian;
Mangas Sanchez, Juan;
Frese, Amina;
Bornscheuer, Uwe T.;
Höhne, Matthias;
Grogan, Gideon

Publication type:

Article

Structure, Activity and Stereoselectivity of NADPH-Dependent Oxidoreductases Catalysing the S-Selective Reduction of the Imine Substrate 2-Methylpyrroline.

Published in:

ChemBioChem, 2015, v. 16, n. 7, p. 1052, doi. 10.1002/cbic.201402625

By:

Man, Henry;
Wells, Elizabeth;
Hussain, Shahed;
Leipold, Friedemann;
Hart, Sam;
Turkenburg, Johan P.;
Turner, Nicholas J.;
Grogan, Gideon

Publication type:

Article

Structures of the Apo and FAD-Bound Forms of 2-Hydroxybiphenyl 3-monooxygenase (HbpA) Locate Activity Hotspots Identified by Using Directed Evolution.

Published in:

ChemBioChem, 2015, v. 16, n. 6, p. 968, doi. 10.1002/cbic.201402701

By:

Jensen, Chantel N.;
Mielke, Tamara;
Farrugia, Joseph E.;
Frank, Annika;
Man, Henry;
Hart, Sam;
Turkenburg, Johan P.;
Grogan, Gideon

Publication type:

Article

Tolerance of β-diketone hydrolases as representatives of the crotonase superfamily towards organic solvents.

Published in:

Biotechnology & Bioengineering, 2011, v. 108, n. 12, p. 2815, doi. 10.1002/bit.23275

By:

Siirola, Elina;
Grischek, Barbara;
Clay, Dorina;
Frank, Annika;
Grogan, Gideon;
Kroutil, Wolfgang

Publication type:

Article

Biotransformation of β-myrcene to geraniol by a strain of Rhodococcus erythropolis isolated by selective enrichment from hop plants.

Published in:

Applied Microbiology & Biotechnology, 2010, v. 85, n. 3, p. 721, doi. 10.1007/s00253-009-2182-6

By:

Thompson, Mark L.;
Marriott, Ray;
Dowle, Adam;
Grogan, Gideon

Publication type:

Article

A refined picture of the native amine dehydrogenase family revealed by extensive biodiversity screening.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49009-2

By:

Elisée, Eddy;
Ducrot, Laurine;
Méheust, Raphaël;
Bastard, Karine;
Fossey-Jouenne, Aurélie;
Grogan, Gideon;
Pelletier, Eric;
Petit, Jean-Louis;
Stam, Mark;
de Berardinis, Véronique;
Zaparucha, Anne;
Vallenet, David;
Vergne-Vaxelaire, Carine

Publication type:

Article

Unspecific Peroxygenase (UPO) can be Tuned for Oxygenation or Halogenation Activity by Controlling the Reaction pH.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 40, p. 1, doi. 10.1002/chem.202401706

By:

Barber, Verity;
Mielke, Tamara;
Cartwright, Jared;
Díaz‐Rodríguez, Alba;
Unsworth, William P.;
Grogan, Gideon

Publication type:

Article

Divergent Cascade Ring‐Expansion Reactions of Acryloyl Imides.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 8, p. 1, doi. 10.1002/chem.202303270

By:

Orukotan, Will E.;
Palate, Kleopas Y.;
Pogrányi, Balázs;
Bobinski, Philipp;
Epton, Ryan G.;
Duff, Lee;
Whitwood, Adrian C.;
Grogan, Gideon;
Lynam, Jason M.;
Unsworth, William P.

Publication type:

Article

Preparative‐Scale Biocatalytic Oxygenation of N‐Heterocycles with a Lyophilized Peroxygenase Catalyst.

Published in:

Angewandte Chemie, 2023, v. 135, n. 5, p. 1, doi. 10.1002/ange.202214759

By:

Pogrányi, Balázs;
Mielke, Tamara;
Díaz‐Rodríguez, Alba;
Cartwright, Jared;
Unsworth, William P.;
Grogan, Gideon

Publication type:

Article

Oxalate Oxidase for In Situ H2O2‐Generation in Unspecific Peroxygenase‐Catalysed Drug Oxyfunctionalisations**.

Published in:

Angewandte Chemie, 2022, v. 134, n. 39, p. 1, doi. 10.1002/ange.202207831

By:

Romero, Elvira;
Johansson, Magnus J.;
Cartwright, Jared;
Grogan, Gideon;
Hayes, Martin A.

Publication type:

Article

Chromoselective Photocatalysis Enables Stereocomplementary Biocatalytic Pathways**.

Published in:

Angewandte Chemie, 2021, v. 133, n. 13, p. 7041, doi. 10.1002/ange.202100164

By:

Schmermund, Luca;
Reischauer, Susanne;
Bierbaumer, Sarah;
Winkler, Christoph K.;
Diaz‐Rodriguez, Alba;
Edwards, Lee J.;
Kara, Selin;
Mielke, Tamara;
Cartwright, Jared;
Grogan, Gideon;
Pieber, Bartholomäus;
Kroutil, Wolfgang

Publication type:

Article

S‐Adenosyl Methionine Cofactor Modifications Enhance the Biocatalytic Repertoire of Small Molecule C‐Alkylation.

Published in:

Angewandte Chemie, 2019, v. 131, n. 49, p. 17747, doi. 10.1002/ange.201908681

By:

McKean, Iain J. W.;
Sadler, Joanna C.;
Cuetos, Anibal;
Frese, Amina;
Humphreys, Luke D.;
Grogan, Gideon;
Hoskisson, Paul A.;
Burley, Glenn A.

Publication type:

Article

The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides.

Published in:

Angewandte Chemie, 2018, v. 130, n. 36, p. 11758, doi. 10.1002/ange.201804592

By:

Petchey, Mark;
Cuetos, Anibal;
Rowlinson, Benjamin;
Dannevald, Stephanie;
Frese, Amina;
Sutton, Peter W.;
Lovelock, Sarah;
Lloyd, Richard C.;
Fairlamb, Ian J. S.;
Grogan, Gideon

Publication type:

Article

Recent Advances in ω-Transaminase-Mediated Biocatalysis for the Enantioselective Synthesis of Chiral Amines.

Published in:

Catalysts (2073-4344), 2018, v. 8, n. 7, p. 254, doi. 10.3390/catal8070254

By:

D. Patil, Mahesh;
Grogan, Gideon;
Bommarius, Andreas;
Yun, Hyungdon

Publication type:

Article

NAD(P)H‐Dependent Enzymes for Reductive Amination: Active Site Description and Carbonyl‐Containing Compound Spectrum.

Published in:

Advanced Synthesis & Catalysis, 2021, v. 363, n. 2, p. 328, doi. 10.1002/adsc.202000870

By:

Ducrot, Laurine;
Bennett, Megan;
Grogan, Gideon;
Vergne‐Vaxelaire, Carine

Publication type:

Article

Enzyme‐Catalysed Synthesis of Secondary and Tertiary Amides.

Published in:

Advanced Synthesis & Catalysis, 2019, v. 361, n. 17, p. 3895, doi. 10.1002/adsc.201900694

By:

Petchey, Mark R.;
Grogan, Gideon

Publication type:

Article

Structure of the imine reductase from Ajellomyces dermatitidis in three crystal forms.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2023, v. 79, n. 9, p. 224, doi. 10.1107/S2053230X23006672

By:

Sharma, Mahima;
Cuetos, Anibal;
Willliams, Adam;
González-Martínez, Daniel;
Grogan, Gideon

Publication type:

Article

Structure-Guided Mechanisms Behind the Metabolism of 2,4,6-Trinitrotoluene by Glutathione Transferases U25 and U24 That Lead to Alternate Product Distribution.

Published in:

Frontiers in Plant Science, 2018, p. N.PAG, doi. 10.3389/fpls.2018.01846

By:

Tzafestas, Kyriakos;
Ahmad, Laziana;
Dani, M. Paulina;
Grogan, Gideon;
Rylott, Elizabeth L.;
Bruce, Neil C.

Publication type:

Article

Characterization and structure‐guided engineering of the novel versatile terpene monooxygenase CYP109Q5 from Chondromyces apiculatus DSM436.

Published in:

Microbial Biotechnology, 2019, v. 12, n. 2, p. 377, doi. 10.1111/1751-7915.13354

By:

Klenk, Jan M.;
Dubiel, Paulina;
Sharma, Mahima;
Grogan, Gideon;
Hauer, Bernhard

Publication type:

Article

Edited by Wolf-Dieter Fessner and Thorleif Anthonsen Modern biocatalysis: stereoselective and environmentally friendly reactions Wiley-VCH, 2008, 400 pp £110.00/€132.00 978-3-527-32071-4 (hardcover).

Published in:

Applied Organometallic Chemistry, 2009, v. 23, n. 6, p. 250, doi. 10.1002/aoc.1499

By:

Grogan, Gideon

Publication type:

Article

SilE‐R and SilE‐S—DABB Proteins Catalying Enantiospecific Hydrolysis of Organosilyl Ethers.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 25, p. 1, doi. 10.1002/anie.202404105

By:

Pick, Lisa M.;
Oehme, Viviane;
Hartmann, Julia;
Wenzlaff, Jessica;
Tang, Qingyun;
Grogan, Gideon;
Ansorge‐Schumacher, Marion B.

Publication type:

Article

Preparative‐Scale Biocatalytic Oxygenation of N‐Heterocycles with a Lyophilized Peroxygenase Catalyst.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 5, p. 1, doi. 10.1002/anie.202214759

By:

Pogrányi, Balázs;
Mielke, Tamara;
Díaz‐Rodríguez, Alba;
Cartwright, Jared;
Unsworth, William P.;
Grogan, Gideon

Publication type:

Article

Oxalate Oxidase for In Situ H2O2‐Generation in Unspecific Peroxygenase‐Catalysed Drug Oxyfunctionalisations**.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 39, p. 1, doi. 10.1002/anie.202207831

By:

Romero, Elvira;
Johansson, Magnus J.;
Cartwright, Jared;
Grogan, Gideon;
Hayes, Martin A.

Publication type:

Article

Chromoselective Photocatalysis Enables Stereocomplementary Biocatalytic Pathways**.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 13, p. 6965, doi. 10.1002/anie.202100164

By:

Schmermund, Luca;
Reischauer, Susanne;
Bierbaumer, Sarah;
Winkler, Christoph K.;
Diaz‐Rodriguez, Alba;
Edwards, Lee J.;
Kara, Selin;
Mielke, Tamara;
Cartwright, Jared;
Grogan, Gideon;
Pieber, Bartholomäus;
Kroutil, Wolfgang

Publication type:

Article

S‐Adenosyl Methionine Cofactor Modifications Enhance the Biocatalytic Repertoire of Small Molecule C‐Alkylation.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 49, p. 17583, doi. 10.1002/anie.201908681

By:

McKean, Iain J. W.;
Sadler, Joanna C.;
Cuetos, Anibal;
Frese, Amina;
Humphreys, Luke D.;
Grogan, Gideon;
Hoskisson, Paul A.;
Burley, Glenn A.

Publication type:

Article

Engineered Biocatalyst for Enantioselective Hydrazone Reduction.

Published in:

Angewandte Chemie, 2025, v. 137, n. 26, p. 1, doi. 10.1002/ange.202424350

By:

Hutton, Amy E.;
Zhao, Fei;
Ho, Elizabeth;
Domenech, Jack;
Harawa, Vanessa;
Brown, Murray J. B.;
Grogan, Gideon;
Clayman, Phillip D.;
Turner, Nicholas J.;
Green, Anthony P.

Publication type:

Article

Divergent Oxidation Reactions of E‐ and Z‐Allylic Primary Alcohols by an Unspecific Peroxygenase.

Published in:

Angewandte Chemie, 2025, v. 137, n. 12, p. 1, doi. 10.1002/ange.202422241

By:

Li, Jiacheng;
Duran, Cristina;
Pogrányi, Balázs;
Cornish, Katy A. S.;
Cartwright, Jared;
Osuna, Sílvia;
Unsworth, William P.;
Grogan, Gideon

Publication type:

Article

SilE−R und SilE−S – DABB‐Proteine mit der Fähigkeit zur enantiospezifischen Hydrolyse von Organosilylethern.

Published in:

Angewandte Chemie, 2024, v. 136, n. 25, p. 1, doi. 10.1002/ange.202404105

By:

Pick, Lisa M.;
Oehme, Viviane;
Hartmann, Julia;
Wenzlaff, Jessica;
Tang, Qingyun;
Grogan, Gideon;
Ansorge‐Schumacher, Marion B.

Publication type:

Article

Identification and characterization of cytochrome P450 1232A24 and 1232F1 from Arthrobacter sp. and their role in the metabolic pathway of papaverine.

Published in:

Journal of Biochemistry, 2019, v. 166, n. 1, p. 51, doi. 10.1093/jb/mvz010

By:

Klenk, Jan M;
Fischer, Max-Philipp;
Dubiel, Paulina;
Sharma, Mahima;
Rowlinson, Benjamin;
Grogan, Gideon;
Hauer, Bernhard

Publication type:

Article

Structure and Activity of NADPH-Dependent Reductase Q1EQE0 from Streptomyces kanamyceticus, which Catalyses the R-Selective Reduction of an Imine Substrate.

Published in:

ChemBioChem, 2013, v. 14, n. 11, p. 1372, doi. 10.1002/cbic.201300321

By:

Rodríguez‐Mata, María;
Frank, Annika;
Wells, Elizabeth;
Leipold, Friedemann;
Turner, Nicholas J.;
Hart, Sam;
Turkenburg, Johan P.;
Grogan, Gideon

Publication type:

Article

A Gene-Fusion Approach to Enabling Plant Cytochromes P450 for Biocatalysis.

Published in:

ChemBioChem, 2012, v. 13, n. 18, p. 2758, doi. 10.1002/cbic.201200572

By:

Schückel, Julia;
Rylott, Elizabeth L.;
Grogan, Gideon;
Bruce, Neil C.

Publication type:

Article

A Flavoprotein Monooxygenase that Catalyses a Baeyer-Villiger Reaction and Thioether Oxidation Using NADH as the Nicotinamide Cofactor.

Published in:

ChemBioChem, 2012, v. 13, n. 6, p. 872, doi. 10.1002/cbic.201200006

By:

Jensen, Chantel N.;
Cartwright, Jared;
Ward, Jonathan;
Hart, Sam;
Turkenburg, Johan P.;
Ali, Sohail T.;
Allen, Michael J.;
Grogan, Gideon

Publication type:

Article

LICRED: A Versatile Drop-In Vector for Rapid Generation of Redox-Self-Sufficient Cytochrome P450s.

Published in:

ChemBioChem, 2010, v. 11, n. 7, p. 987, doi. 10.1002/cbic.201000104

By:

Sabbadin, Federico;
Hyde, Ralph;
Robin, Aelig;
Hilgarth, Eva-Maria;
Delenne, Marie;
Flitsch, Sabine;
Turner, Nicholas;
Grogan, Gideon;
Bruce, Neil C.

Publication type:

Article

Insights into Sequence-Activity Relationships amongst Baeyer-Villiger Monooxygenases as Revealed by the Intragenomic Complement of Enzymes from Rhodococcus jostii RHA1.

Published in:

ChemBioChem, 2009, v. 10, n. 7, p. 1208, doi. 10.1002/cbic.200900011

By:

Szolkowy, Claudia;
Eltis, Lindsay D.;
Bruce, Neil C.;
Grogan, Gideon

Publication type:

Article

The Right Light: De Novo Design of a Robust Modular Photochemical Reactor for Optimum Batch and Flow Chemistry.

Published in:

ChemPhotoChem, 2020, v. 4, n. 1, p. 45, doi. 10.1002/cptc.201900203

By:

Bonfield, Holly E.;
Mercer, Kayleigh;
Diaz‐Rodriguez, Alba;
Cook, Gemma C.;
McKay, Blandine S. J.;
Slade, Pawel;
Taylor, George M.;
Ooi, Wei Xiang;
Williams, Jason D.;
Roberts, Jack P. M.;
Murphy, John A.;
Schmermund, Luca;
Kroutil, Wolfgang;
Mielke, Tamara;
Cartwright, Jared;
Grogan, Gideon;
Edwards, Lee J.

Publication type:

Article

An Asymmetric Enzyme-Catalyzed Retro-Claisen Reaction for the Desymmetrization of Cyclic β-Diketones.

Published in:

Angewandte Chemie International Edition, 2001, v. 40, n. 6, p. 1111, doi. 10.1002/1521-3773(20010316)40:6<1111::AID-ANIE11110>3.0.CO;2-2

By:

Grogan, Gideon;
Graf, Jürgen;
Jones, Aileen;
Parsons, Simon;
Turner, Nicholas J.;
Flitsch, Sabine L.

Publication type:

Article

InspIRED by Nature: NADPH-Dependent Imine Reductases (IREDs) as Catalysts for the Preparation of Chiral Amines.

Published in:

Chemistry - A European Journal, 2016, v. 22, n. 6, p. 1900, doi. 10.1002/chem.201503954

By:

Grogan, Gideon;
Turner, Nicholas J.

Publication type:

Article

Biocatalytic Conversion of Cyclic Ketones Bearing α‐Quaternary Stereocenters into Lactones in an Enantioselective Radical Approach to Medium‐Sized Carbocycles.

Published in:

Angewandte Chemie, 2018, v. 130, n. 14, p. 3754, doi. 10.1002/ange.201800121

By:

Morrill, Charlotte;
Jensen, Chantel;
Just‐Baringo, Xavier;
Grogan, Gideon;
Turner, Nicholas J.;
Procter, David J.

Publication type:

Article

Biocatalytic Routes to Enantiomerically Enriched Dibenz[ c, e]azepines.

Published in:

Angewandte Chemie, 2017, v. 129, n. 49, p. 15795, doi. 10.1002/ange.201708453

By:

France, Scott P.;
Aleku, Godwin A.;
Sharma, Mahima;
Mangas‐Sanchez, Juan;
Howard, Roger M.;
Steflik, Jeremy;
Kumar, Rajesh;
Adams, Ralph W.;
Slabu, Iustina;
Crook, Robert;
Grogan, Gideon;
Wallace, Timothy W.;
Turner, Nicholas J.

Publication type:

Article

Catalytic Promiscuity of Transaminases: Preparation of Enantioenriched β-Fluoroamines by Formal Tandem Hydrodefluorination/Deamination.

Published in:

Angewandte Chemie, 2016, v. 128, n. 9, p. 3196, doi. 10.1002/ange.201510554

By:

Cuetos, Aníbal;
García ‐ Ramos, Marina;
Fischereder, Eva ‐ Maria;
Díaz ‐ Rodríguez, Alba;
Grogan, Gideon;
Gotor, Vicente;
Kroutil, Wolfgang;
Lavandera, Iván

Publication type:

Article

Inversion of Enantioselectivity of a Mononuclear Non-Heme Iron(II)-dependent Hydroxylase by Tuning the Interplay of Metal-Center Geometry and Protein Structure.

Published in:

Angewandte Chemie, 2013, v. 125, n. 37, p. 9859, doi. 10.1002/ange.201304633

By:

Pratter, Sarah M.;
Konstantinovics, Cornelia;
Di Giuro, Cristiana M. L.;
Leitner, Erich;
Kumar, Devesh;
de Visser, Sam P.;
Grogan, Gideon;
Straganz, Grit D.

Publication type:

Article

Enzymatic esterification of lavandulol – a partial kinetic resolution of (S)-lavandulol and preparation of optically enriched (R)-lavandulyl acetate.

Published in:

Biotechnology Letters, 2004, v. 26, n. 5, p. 457, doi. 10.1023/B:BILE.0000018268.42802.d0

By:

Cross, Hannah;
Marriott, Ray;
Grogan, Gideon

Publication type:

Article

Diastereoselective hydroxylation and reduction of derivatised tetrahydrofurans by Beauveria bassiana.

Published in:

Biotechnology Letters, 2001, v. 23, n. 2, p. 119, doi. 10.1023/A:1010393216458

By:

Grogan, Gideon;
Sime, John T.;
Turner, Nicholas J.

Publication type:

Article

Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands.

Published in:

FEBS Open Bio, 2017, v. 7, n. 2, p. 122, doi. 10.1002/2211-5463.12168

By:

Ahmad, Laziana;
Rylott, Elizabeth L.;
Bruce, Neil C.;
Edwards, Robert;
Grogan, Gideon

Publication type:

Article

Mutations of an NAD(P)H-dependent flavoprotein monooxygenase that influence cofactor promiscuity and enantioselectivity.

Published in:

FEBS Open Bio, 2013, v. 3, p. 473, doi. 10.1016/j.fob.2013.09.008

By:

Jensen, Chantel N.;
Ali, Sohail T.;
Allen, Michael J.;
Grogan, Gideon

Publication type:

Article

Mutations of an NAD(P)H‐dependent flavoprotein monooxygenase that influence cofactor promiscuity and enantioselectivity.

Published in:

FEBS Open Bio, 2013, v. 3, n. 1, p. 473, doi. 10.1016/j.fob.2013.09.008

By:

Jensen, Chantel N.;
Ali, Sohail T.;
Allen, Michael J.;
Grogan, Gideon

Publication type:

Article