Works by Grimes, Graeme R.

Results: 15

Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60655-y

By:

Ewing, Ailith;
Meynert, Alison;
Silk, Ryan;
Aitken, Stuart;
Bendixsen, Devin P.;
Churchman, Michael;
Brown, Stuart L.;
Hamdan, Alhafidz;
Mattocks, Joanne;
Grimes, Graeme R.;
Ballinger, Tracy;
Hollis, Robert L.;
Simon Herrington, C.;
Thomson, John P.;
Sherwood, Kitty;
Parry, Thomas;
Esiri-Bloom, Edward;
Bartos, Clare;
Croy, Ian;
Ferguson, Michelle

Publication type:

Article

Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia.

Published in:

PLoS ONE, 2022, v. 17, n. 11, p. 1, doi. 10.1371/journal.pone.0268149

By:

Hall, Hildegard Nikki;
Bengani, Hemant;
Hufnagel, Robert B.;
Damante, Giuseppe;
Ansari, Morad;
Marsh, Joseph A.;
Grimes, Graeme R.;
Kriegsheim, Alex von;
Moore, David;
McKie, Lisa;
Rahmat, Jamalia;
Mio, Catia;
Blyth, Moira;
Keng, Wee Teik;
Islam, Lily;
McEntargart, Meriel;
Mannens, Marcel M.;
Heyningen, Veronica Van;
Rainger, Joe;
Brooks, Brian P.

Publication type:

Article

Correction: Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops.

Published in:

Life Science Alliance, 2024, v. 7, n. 1, p. 1, doi. 10.26508/lsa.202302436

By:

Williamson, Iain;
Boyle, Shelagh;
Grimes, Graeme R.;
Friman, Elias T.;
Bickmore, Wendy A.

Publication type:

Article

Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops.

Published in:

Life Science Alliance, 2023, v. 6, n. 10, p. 1, doi. 10.26508/lsa.202302101

By:

Williamson, Iain;
Boyle, Shelagh;
Grimes, Graeme R.;
Friman, Elias T.;
Bickmore, Wendy A.

Publication type:

Article

Characterisation of a nucleo-adhesome.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30556-5

By:

Byron, Adam;
Griffith, Billie G. C.;
Herrero, Ana;
Loftus, Alexander E. P.;
Koeleman, Emma S.;
Kogerman, Linda;
Dawson, John C.;
McGivern, Niamh;
Culley, Jayne;
Grimes, Graeme R.;
Serrels, Bryan;
von Kriegsheim, Alex;
Brunton, Valerie G.;
Frame, Margaret C.

Publication type:

Article

Cornelia de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23500-6

By:

Olley, Gabrielle;
Pradeepa, Madapura M.;
Grimes, Graeme R.;
Piquet, Sandra;
Polo, Sophie E.;
FitzPatrick, David R.;
Bickmore, Wendy A.;
Boumendil, Charlene

Publication type:

Article

Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing.

Published in:

PLoS Genetics, 2012, v. 8, n. 5, p. 1, doi. 10.1371/journal.pgen.1002717

By:

Pradeepa, Madapura M.;
Sutherland, Heidi G.;
Ule, Jernej;
Grimes, Graeme R.;
Bickmore, Wendy A.

Publication type:

Article

Human centromere repositioning activates transcription and opens chromatin fibre structure.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33426-2

By:

Naughton, Catherine;
Huidobro, Covadonga;
Catacchio, Claudia R.;
Buckle, Adam;
Grimes, Graeme R.;
Nozawa, Ryu-Suke;
Purgato, Stefania;
Rocchi, Mariano;
Gilbert, Nick

Publication type:

Article

Identifying and overcoming a mechanism of resistance to WEE1 kinase inhibitor AZD1775 in high grade serous ovarian cancer cells.

Published in:

European Journal of Gynaecological Oncology, 2022, v. 43, n. 2, p. 183, doi. 10.31083/j.ejgo4302024

By:

Gomez, Miriam K.;
Thomson, John P.;
Grimes, Graeme R.;
Wang, Anderson T.;
Churchman, Michael;
O'Connor, Mark J.;
Gourley, Charlie;
Melton, David W.

Publication type:

Article

Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 14, p. 9021, doi. 10.1093/nar/gku647

By:

Pradeepa, Madapura M.;
Grimes, Graeme R.;
Taylor, Gillian C.A.;
Sutherland, Heidi G.;
Bickmore, Wendy A.

Publication type:

Article

FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80111-9

By:

Griffith, Billie G. C.;
Upstill-Goddard, Rosanna;
Brunton, Holly;
Grimes, Graeme R.;
Biankin, Andrew V.;
Serrels, Bryan;
Byron, Adam;
Frame, Margaret C.

Publication type:

Article

PRC1 and PRC2 Are Not Required for Targeting of H2A.Z to Developmental Genes in Embryonic Stem Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034848

By:

Illingworth, Robert S.;
Botting, Catherine H.;
Grimes, Graeme R.;
Bickmore, Wendy A.;
Eskeland, Ragnhild

Publication type:

Article

Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip.

Published in:

PLoS Genetics, 2017, v. 13, n. 4, p. 1, doi. 10.1371/journal.pgen.1006677

By:

Pradeepa, Madapura M.;
McKenna, Fionnuala;
Taylor, Gillian C. A.;
Bengani, Hemant;
Grimes, Graeme R.;
Wood, Andrew J.;
Bhatia, Shipra;
Bickmore, Wendy A.

Publication type:

Article

Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF.

Published in:

European Journal of Immunology, 2011, v. 41, n. 11, p. 3291, doi. 10.1002/eji.201141648

By:

Semple, Fiona;
MacPherson, Heather;
Webb, Sheila;
Cox, Sarah L.;
Mallin, Lucy J.;
Tyrrell, Christine;
Grimes, Graeme R.;
Semple, Colin A.;
Nix, Matthew A.;
Millhauser, Glenn L.;
Dorin, Julia R.

Publication type:

Article

GPX-Macrophage Expression Atlas: A database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insults.

Published in:

BMC Genomics, 2005, v. 6, p. 178, doi. 10.1186/1471-2164-6-178

By:

Grimes, Graeme R;
Moodie, Stuart;
Beattie, John S;
Craigon, Marie;
Dickinson, Paul;
Forster, Thorsten;
Livingston, Andrew D;
Mewissen, Muriel;
Robertson, Kevin A;
Ross, Alan J;
Sing, Garwin;
Ghazal, Peter

Publication type:

Article