Works by Grez, Manuel

Results: 40

Cirujano Edwards Crisp y Síndrome de Valentino.

Published in:

Revista de Cirugia, 2025, v. 77, n. 3, p. 328, doi. 10.35687/s2452-454920250032572

By:

Grez Ibáñez, Manuel Antonio;
Sandoval B., Jorge;
Ubal Castañeda, Valentina

Publication type:

Article

Trichostatin A induces 5-lipoxygenase promoter activity and mRNA expression via inhibition of histone deacetylase 2 and 3.

Published in:

Journal of Cellular & Molecular Medicine, 2012, v. 16, n. 7, p. 1461, doi. 10.1111/j.1582-4934.2011.01420.x

By:

Pufahl, Laura;
Katryniok, Careen;
Schnur, Nicole;
Sorg, Bernd L.;
Metzner, Julia;
Grez, Manuel;
Steinhilber, Dieter

Publication type:

Article

Muerte súbita cardíaca por displasia arritmogénica del ventrículo derecho en posoperatorio inmediato.

Published in:

Revista Hispanoamericana de Hernia, 2023, v. 11, n. 3, p. 139, doi. 10.20960/rhh.00304

By:

Grez Ibáñez, Manuel;
Elías Delgado, Mario A.;
Bustos Baquerizo, Vivian

Publication type:

Article

Hernioplastia con doble malla en eventración subxifoidea por esternotomía media con manutención de Aspirina<sup>®</sup>.

Published in:

Revista Hispanoamericana de Hernia, 2022, v. 10, n. 4, p. 196, doi. 10.20960/rhh.00377

By:

Grez Ibáñez, Manuel Antonio;
Sánchez Medina, Rixio Abner;
Silva Torres, Amaranda

Publication type:

Article

MiR144/451 Expression Is Repressed by RUNX1 During Megakaryopoiesis and Disturbed by RUNX1/ETO.

Published in:

PLoS Genetics, 2016, v. 12, n. 3, p. 1, doi. 10.1371/journal.pgen.1005946

By:

Kohrs, Nicole;
Kolodziej, Stephan;
Kuvardina, Olga N.;
Herglotz, Julia;
Yillah, Jasmin;
Herkt, Stefanie;
Piechatzek, Alexander;
Salinas Riester, Gabriela;
Lingner, Thomas;
Wichmann, Christian;
Bonig, Halvard;
Seifried, Erhard;
Platzbecker, Uwe;
Medyouf, Hind;
Grez, Manuel;
Lausen, Jörn

Publication type:

Article

Gene therapy on the move.

Published in:

EMBO Molecular Medicine, 2013, v. 5, n. 11, p. 1642, doi. 10.1002/emmm.201202287

By:

Kaufmann, Kerstin B.;
Büning, Hildegard;
Galy, Anne;
Schambach, Axel;
Grez, Manuel

Publication type:

Article

Dendritic cells lentivirally engineered to overexpress interleukin-10 inhibit contact hypersensitivity responses, despite their partial activation induced by transduction-associated physical stress.

Published in:

Journal of Gene Medicine, 2010, v. 12, n. 3, p. 231, doi. 10.1002/jgm.1436

By:

Besche, Verena;
Wiechmann, Nadine;
Castor, Timo;
Trojandt, Stefanie;
Höhn, Yvonne;
Kunkel, Hanna;
Grez, Manuel;
Grabbe, Stephan;
Reske-Kunz, Angelika B.;
Bros, Matthias

Publication type:

Article

Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor.

Published in:

Molecular Therapy, 2015, v. 23, n. 2, p. 330, doi. 10.1038/mt.2014.219

By:

Schönfeld, Kurt;
Sahm, Christiane;
Zhang, Congcong;
Brendel, Christian;
Köhler, Sylvia;
Grez, Manuel;
Rieger, Michael A;
Wels, Winfried S;
Naundorf, Sonja;
Kühlcke, Klaus;
Odendahl, Marcus;
Tonn, Torsten;
Nowakowska, Paulina;
Bönig, Halvard;
Seifried, Erhard;
Köhl, Ulrike;
Kloess, Stephan;
Holtgreve-Grez, Heidi;
Jauch, Anna;
Schmidt, Manfred

Publication type:

Article

CD133-targeted Gene Transfer Into Long-term Repopulating Hematopoietic Stem Cells.

Published in:

Molecular Therapy, 2015, v. 23, n. 1, p. 63, doi. 10.1038/mt.2014.173

By:

Brendel, Christian;
Goebel, Benjamin;
Daniela, Abriss;
Brugman, Martijn;
Kneissl, Sabrina;
Schwäble, Joachim;
Kaufmann, Kerstin B;
Müller-Kuller, Uta;
Kunkel, Hana;
Chen-Wichmann, Linping;
Abel, Tobias;
Serve, Hubert;
Bystrykh, Leonid;
Buchholz, Christian J;
Grez, Manuel

Publication type:

Article

Dual-regulated Lentiviral Vector for Gene Therapy of X-linked Chronic Granulomatosis.

Published in:

Molecular Therapy, 2014, v. 22, n. 8, p. 1472, doi. 10.1038/mt.2014.87

By:

Chiriaco, Maria;
Farinelli, Giada;
Capo, Valentina;
Zonari, Erika;
Scaramuzza, Samantha;
Di Matteo, Gigliola;
Sergi, Lucia Sergi;
Migliavacca, Maddalena;
Hernandez, Raisa Jofra;
Bombelli, Ferdinando;
Giorda, Ezio;
Kajaste-Rudnitski, Anna;
Trono, Didier;
Grez, Manuel;
Rossi, Paolo;
Finocchi, Andrea;
Naldini, Luigi;
Gentner, Bernhard;
Aiuti, Alessandro

Publication type:

Article

Alpharetroviral Vector-mediated Gene Therapy for X-CGD: Functional Correction and Lack of Aberrant Splicing.

Published in:

Molecular Therapy, 2013, v. 21, n. 3, p. 648, doi. 10.1038/mt.2012.249

By:

Kaufmann, Kerstin B.;
Brendel, Christian;
Suerth, Julia D.;
Mueller-Kuller, Uta;
Chen-Wichmann, Linping;
Schwäble, Joachim;
Pahujani, Shweta;
Kunkel, Hana;
Schambach, Axel;
Baum, Christopher;
Grez, Manuel

Publication type:

Article

Alpharetroviral Self-inactivating Vectors: Long-term Transgene Expression in Murine Hematopoietic Cells and Low Genotoxicity.

Published in:

Molecular Therapy, 2012, v. 20, n. 5, p. 1022, doi. 10.1038/mt.2011.309

By:

Suerth, Julia D;
Maetzig, Tobias;
Brugman, Martijn H;
Heinz, Niels;
Appelt, Jens-Uwe;
Kaufmann, Kerstin B;
Schmidt, Manfred;
Grez, Manuel;
Modlich, Ute;
Baum, Christopher;
Schambach, Axel

Publication type:

Article

Insertion Sites in Engrafted Cells Cluster Within a Limited Repertoire of Genomic Areas After Gammaretroviral Vector Gene Therapy.

Published in:

Molecular Therapy, 2011, v. 19, n. 11, p. 2031, doi. 10.1038/mt.2011.178

By:

Deichmann, Annette;
Brugman, Martijn H;
Bartholomae, Cynthia C;
Schwarzwaelder, Kerstin;
Verstegen, Monique MA;
Howe, Steven J;
Arens, Anne;
Ott, Marion G;
Hoelzer, Dieter;
Seger, Reinhard;
Grez, Manuel;
Hacein-Bey-Abina, Salima;
Cavazzana-Calvo, Marina;
Fischer, Alain;
Paruzynski, Anna;
Gabriel, Richard;
Glimm, Hanno;
Abel, Ulrich;
Cattoglio, Claudia;
Mavilio, Fulvio

Publication type:

Article

Biochemical Correction of X-CGD by a Novel Chimeric Promoter Regulating High Levels of Transgene Expression in Myeloid Cells.

Published in:

Molecular Therapy, 2011, v. 19, n. 1, p. 122, doi. 10.1038/mt.2010.226

By:

Santilli, Giorgia;
Almarza, Elena;
Brendel, Christian;
Choi, Uimook;
Beilin, Chiara;
Blundell, Michael P.;
Haria, Sneha;
Parsley, Kathryn L.;
Kinnon, Christine;
Malech, Harry L.;
Bueren, Juan A.;
Grez, Manuel;
Thrasher, Adrian J.

Publication type:

Article

Gene Therapy of Chronic Granulomatous Disease: The Engraftment Dilemma.

Published in:

Molecular Therapy, 2011, v. 19, n. 1, p. 28, doi. 10.1038/mt.2010.232

By:

Grez, Manuel;
Reichenbach, Janine;
Schwäble, Joachim;
Seger, Reinhard;
Dinauer, Mary C.;
Thrasher, Adrian J.

Publication type:

Article

An Improved Bicistronic CD20/tCD34 Vector for Efficient Purification and In Vivo Depletion of Gene-Modified T Cells for Adoptive Immunotherapy.

Published in:

Molecular Therapy, 2010, v. 18, n. 7, p. 1330, doi. 10.1038/mt.2010.83

By:

Vogler, Isabel;
Newrzela, Sebastian;
Hartmann, Sylvia;
Schneider, Nadine;
von Laer, Dorothee;
Koehl, Ulrike;
Grez, Manuel

Publication type:

Article

Targeted Cell Entry of Lentiviral Vectors.

Published in:

Molecular Therapy, 2008, v. 16, n. 8, p. 1427, doi. 10.1038/mt.2008.128

By:

Funke, Sabrina;
Maisner, Andrea;
Mühlebach, Michael D.;
Koehl, Ulrike;
Grez, Manuel;
Cattaneo, Roberto;
Cichutek, Klaus;
Buchholz, Christian J.

Publication type:

Article

723. In Vivo Expansion of MDS1/EVI1, PRDM16 and SETBP1 Integration Clones in Successful Chronic Granulomatous Disease (CGD) Gene Therapy Trial.

Published in:

Molecular Therapy, 2006, v. 13, p. S279, doi. 10.1016/j.ymthe.2006.08.803

By:

Schwarzwaelder, Kerstin;
Schmidt, Manfred;
Ott, Marion G.;
Stein, Stefan;
Glimm, Hanno;
Deichmann, Annette;
Siler, Ulrich;
Hoelzer, Dieter;
Seger, Reinhard;
Grez, Manuel;
von Kalle, Christof

Publication type:

Article

1076. Stable Polyclonal Hematopoietic Repopulation after Successful Clinical Gene Therapy of Chronic Granulomatous Disease (CGD)

Published in:

2005

By:

Schmidt, Manfred;
Schwarzwaelder, Kerstin;
Ott, Marion G.;
Stein, Stefan;
Glimm, Hanno;
Deichmann, Annette;
Sieler, Ulrich;
Hoelzer, Dieter;
Seger, Reinhard;
Grez, Manuel;
von Kalle, Christof

Publication type:

Abstract

1045. Overexpression of an ABCG2 Multidrug Transporter Variant Does Not Effect Proliferation or Differentiation of Hematopoetic Stem Cells

Published in:

2005

By:

Ujhelly, Olga;
Kucsma, Nora;
Cervenak, Judith;
Chen, Linping;
Grez, Manuel;
Sarkadi, Balazs;
Nemet, Katalin

Publication type:

Abstract

336. Correction of Chronic Granulomatous Disease by Gene Therapy

Published in:

2005

By:

Grez, Manuel;
Ott, Marion G.;
Stein, Stefan;
Siler, Ulrich;
Koehl, Ulrike;
Kunkel, Hana;
Schilz, Andrea;
Kuehlcke, Klaus;
Hoelzer, Dieter;
Seger, Reinhard

Publication type:

Abstract

332. Chronic Granulomatous Disease Gene Therapy Functionally Corrects the Phenotype of Polymorphonuclear Leukocytes (PMN)

Published in:

2005

By:

Siler, Ulrich;
Ott, Marion G.;
Stein, Stefan;
Karaus, Elke;
Rutishauser, Maja;
Wenk, Corinne;
Hoelzer, Dieter;
Grez, Manuel;
Seger, Reinhard

Publication type:

Abstract

The Twelfth Annual Meeting of the European Society of Gene Therapy

Published in:

2005

By:

Grez, Manuel;
Galun, Eithan;
Moullier, Philippe

Publication type:

Proceeding

A bispecific transmembrane antibody simultaneously targeting intra- and extracellular epitopes of the epidermal growth factor receptor inhibits receptor activation and tumor cell growth.

Published in:

International Journal of Cancer, 2014, v. 134, n. 11, p. 2547, doi. 10.1002/ijc.28585

By:

Müller, Nina;
Hartmann, Cord;
Genßler, Sabrina;
Koch, Joachim;
Kinner, Andrea;
Grez, Manuel;
Wels, Winfried S.

Publication type:

Article

Inhibition of HIV-1 by a Peptide Ligand of the Genomic RNA Packaging Signal Ψ.

Published in:

ChemMedChem, 2008, v. 3, n. 5, p. 749, doi. 10.1002/cmdc.200700194

By:

Dietz, Julia;
Koch, Joachim;
Kaur, Ajit;
Raja, Chinnappan;
Stein, Stefan;
Grez, Manuel;
Pustowka, Anette;
Mensch, Sarah;
Ferner, Jan;
Möller, Lars;
Bannert, Norbert;
Tampé, Robert;
Divita, Gilles;
Mély, Yves;
Schwalbe, Harald;
Dietrich, Ursula

Publication type:

Article

Carcinomatosis peritoneal diagnosticada tan solo por imagenología.

Published in:

Revista de Cirugia, 2024, v. 76, n. 5, p. 411, doi. 10.35687/s2452-454920240052144

By:

Grez Ibáñez, Manuel Antonio;
Rojas Villa, Víctor Hugo

Publication type:

Article

Trauma penetrante cardíaco con permanencia inadvertida intraventricular de hoja metálica del cuchillo.

Published in:

Revista de Cirugia, 2024, v. 76, n. 5, p. 409, doi. 10.35687/s2452-454920240052110

By:

Grez I., Manuel;
Sánchez M., Rixio

Publication type:

Article

Abscedación y fistulización de antiguo oblitoma intraperitoneal a la pared abdominal anterior.

Published in:

Revista de Cirugia, 2024, v. 76, n. 4, p. 309, doi. 10.35687/s2452-454920240042109

By:

Grez I., Manuel;
Antequera V., Luis

Publication type:

Article

A small, portable RNA device for the control of exon skipping in mammalian cells.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 8, p. 1, doi. 10.1093/nar/gky062

By:

Vogel, Marc;
Weigand, Julia E;
Kluge, Britta;
Grez, Manuel;
Suess, Beatrix

Publication type:

Article

A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 3, p. 1577, doi. 10.1093/nar/gkv019

By:

Müller-Kuller, Uta;
Ackermann, Mania;
Kolodziej, Stephan;
Brendel, Christian;
Fritsch, Jessica;
Lachmann, Nico;
Kunkel, Hana;
Lausen, Jörn;
Schambach, Axel;
Moritz, Thomas;
Grez, Manuel

Publication type:

Article

A new level of regulation in gluconeogenesis: metabolic state modulates the intracellular localization of aldolase B and its interaction with liver fructose-1,6-bisphosphatase.

Published in:

Biochemical Journal, 2015, v. 472, n. 2, p. 225, doi. 10.1042/BJ20150269

By:

Droppelmann, Cristian A.;
Sáez, Doris E.;
Asenjo, Joel L.;
Yáñez, Alejandro J.;
García-Rocha, Mar;
Concha, Ilona I.;
Grez, Manuel;
Guinovart, Joan J.;
Slebe, Juan C.

Publication type:

Article

Interference with RUNX1/ETO Leukemogenic Function by Cell-Penetrating Peptides Targeting the NHR2 Oligomerization Domain.

Published in:

BioMed Research International, 2013, v. 2013, p. 1, doi. 10.1155/2013/297692

By:

Bartel, Yvonne;
Grez, Manuel;
Wichmann, Christian

Publication type:

Article

Advantages and applications of CAR-expressing natural killer cells.

Published in:

Frontiers in Pharmacology, 2015, v. 6, p. 1, doi. 10.3389/fphar.2015.00021

By:

Glienke, Wolfgang;
Esser, Ruth;
Priesner, Christoph;
Suerth, Julia D.;
Schambach, Axel;
Wels, Winfried S.;
Grez, Manuel;
Kloess, Stephan;
Arseniev, Lubomir;
Koehl, Ulrike;
German, Nadezhda A.;
Saudemont, Aurore;
Masaki Yasukawa

Publication type:

Article

Post-Transcriptional Regulation of 5-Lipoxygenase mRNA Expression via Alternative Splicing and Nonsense-Mediated mRNA Decay.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031363

By:

Ochs, Meike J.;
Sorg, Bernd L.;
Pufahl, Laura;
Grez, Manuel;
Suess, Beatrix;
Steinhilber, Dieter

Publication type:

Article

A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny.

Published in:

Stem Cells, 2013, v. 31, n. 3, p. 488, doi. 10.1002/stem.1316

By:

Pfaff, Nils;
Lachmann, Nico;
Ackermann, Mania;
Kohlscheen, Saskia;
Brendel, Christian;
Maetzig, Tobias;
Niemann, Heiner;
Antoniou, Michael N.;
Grez, Manuel;
Schambach, Axel;
Cantz, Tobias;
Moritz, Thomas

Publication type:

Article

Mammary Epithelial Reconstitution with Gene-Modified Stem Cells Assigns Roles to Stat5 in Luminal Alveolar Cell Fate Decisions, Differentiation, Involution, and Mammary Tumor Formation.

Published in:

Stem Cells, 2010, v. 28, n. 5, p. 928, doi. 10.1002/stem.407

By:

Vafaizadeh, Vida;
Klemmt, Petra;
Brendel, Christian;
Weber, Kristoffer;
Doebele, Carmen;
Britt, Kara;
Grez, Manuel;
Fehse, Boris;
Desriviéres, Sylvane;
Groner, Bernd

Publication type:

Article

Rho Inhibition Induces Migration of Mesenchymal Stromal Cells.

Published in:

Stem Cells, 2007, v. 25, n. 8, p. 1966, doi. 10.1634/stemcells.2007-0167

By:

Bithiah Grace Jaganathan;
Ruester, Brigitte;
Dressel, Lars;
Stein, Stefan;
Grez, Manuel;
Seifried, Erhard;
Henschler, Reinhard

Publication type:

Article

Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.13909

By:

Coutandin, Daniel;
Osterburg, Christian;
Srivastav, Ratnesh Kumar;
Sumyk, Manuela;
Kehrloesser, Sebastian;
Gebel, Jakob;
Tuppi, Marcel;
Hannewald, Jens;
Schäfer, Birgit;
Salah, Eidarus;
Mathea, Sebastian;
Müller-Kuller, Uta;
Doutch, James;
Grez, Manuel;
Knapp, Stefan;
Dötsch, Volker

Publication type:

Article

ERBB2/HER2-SPECIFIC NATURAL KILLER CELLS FOR ADOPTIVE IMMUNOTHERAPY OF GLIOBLASTOMA.

Published in:

Neuro-Oncology, 2014, v. 16, n. suppl_3, p. iii44, doi. 10.1093/neuonc/nou209.9

By:

Steinbach, Joachim P.;
Zhang, Congcong;
Burger, Michael;
Jennewein, Lukas;
Schönfeld, Kurt;
Genßler, Sabrina;
Sahm, Christiane;
Brendel, Christian;
Naundorf, Sonja;
Odendahl, Marcus;
Köhl, Ulrike;
Nowakowska, Paulina;
Seifried, Erhard;
Bönig, Halvard;
Tonn, Torsten;
Grez, Manuel;
Mittelbronn, Michel;
Wels, Winfried S.

Publication type:

Article

UPF1 regulates myeloid cell functions and S100A9 expression by the hnRNP E2/miRNA-328 balance.

Published in:

Scientific Reports, 2016, p. 31995, doi. 10.1038/srep31995

By:

Saul, Meike J.;
Stein, Stefan;
Grez, Manuel;
Jakobsson, Per-Johan;
Steinhilber, Dieter;
Suess, Beatrix

Publication type:

Article