Works by Greupink, Rick

Results: 27

Non‐clinical considerations for supporting accelerated inclusion of pregnant women in pre‐licensure clinical trials with anti‐HIV agents.

Published in:

Journal of the International AIDS Society, 2022, v. 25, p. 1, doi. 10.1002/jia2.25914

By:

Greupink, Rick;
van Hove, Hedwig;
Mhlanga, Felix;
Theunissen, Peter;
Colbers, Angela

Publication type:

Article

Prediction of Moxifloxacin Concentrations in Tuberculosis Patient Populations by Physiologically Based Pharmacokinetic Modeling.

Published in:

Journal of Clinical Pharmacology, 2022, v. 62, n. 3, p. 385, doi. 10.1002/jcph.1972

By:

Litjens, Carlijn H. C.;
Verscheijden, Laurens F. M.;
Bolwerk, Celine;
Greupink, Rick;
Koenderink, Jan B.;
van den Broek, Petra H. H.;
van den Heuvel, Jeroen J. M. W.;
Svensson, Elin M.;
Boeree, Martin J.;
Magis-Escurra, Cecile;
Hoefsloot, Wouter;
van Crevel, Reinout;
van Laarhoven, Arjan;
van Ingen, Jakko;
Kuipers, Saskia;
Ruslami, Rovina;
Burger, David M.;
Russel, Frans G. M.;
Aarnoutse, Rob E.;
te Brake, Lindsey H. M.

Publication type:

Article

Evaluating darunavir/ritonavir dosing regimens for HIV-positive pregnant women using semi-mechanistic pharmacokinetic modelling.

Published in:

2019

By:

Schalkwijk, Stein;
Heine, Rob ter;
Colbers, Angela;
Capparelli, Edmund;
Best, Brookie M;
Cressey, Tim R;
Greupink, Rick;
Russel, Frans G M;
Moltó, José;
Mirochnick, Mark;
Karlsson, Mats O;
Burger, David M;
Ter Heine, Rob

Publication type:

journal article

Placental transfer of the HIV integrase inhibitor dolutegravir in an ex vivo human cotyledon perfusion model.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2016, v. 71, n. 2, p. 480, doi. 10.1093/jac/dkv358

By:

Schalkwijk, Stein;
Greupink, Rick;
Colbers, Angela P.;
Wouterse, Alfons C.;
Verweij, Vivienne G. M.;
van Drongelen, Joris;
Teulen, Marga;
van den Oetelaar, Daphne;
Burger, David M.;
Russel, Frans G. M.

Publication type:

Article

Drug Dosing in Pregnant Women: Challenges and Opportunities in Using Physiologically Based Pharmacokinetic Modeling and Simulations.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2018, v. 7, n. 2, p. 103, doi. 10.1002/psp4.12274

By:

Ke, Alice Ban;
Greupink, Rick;
Abduljalil, Khaled

Publication type:

Article

Review article: direct‐acting antivirals for the treatment of HCV during pregnancy and lactation ‐ implications for maternal dosing, foetal exposure, and safety for mother and child.

Published in:

Alimentary Pharmacology & Therapeutics, 2019, v. 50, n. 7, p. 738, doi. 10.1111/apt.15476

By:

Freriksen, Jolien J. M.;
Seyen, Minou;
Judd, Ali;
Gibb, Diana M.;
Collins, Intira J.;
Greupink, Rick;
Russel, Frans G. M.;
Drenth, Joost P. H.;
Colbers, Angela;
Burger, David M.

Publication type:

Article

Toxicity of anticancer drugs in human placental tissue explants and trophoblast cell lines.

Published in:

Archives of Toxicology, 2021, v. 95, n. 2, p. 557, doi. 10.1007/s00204-020-02925-w

By:

Eliesen, Gaby A. M.;
van Hove, Hedwig;
Meijer, Maartje H.;
van den Broek, Petra H. H.;
Pertijs, Jeanne;
Roeleveld, Nel;
van Drongelen, Joris;
Russel, Frans G. M.;
Greupink, Rick

Publication type:

Article

Rat precision-cut liver slices predict drug-induced cholestatic injury.

Published in:

Archives of Toxicology, 2017, v. 91, n. 10, p. 3403, doi. 10.1007/s00204-017-1960-7

By:

Starokozhko, Viktoriia;
Greupink, Rick;
van de Broek, Petra;
Soliman, Nashwa;
Ghimire, Samiksha;
de Graaf, Inge;
Groothuis, Geny

Publication type:

Article

POTENTIALS AND LIMITATIONS OF THE LOW-MOLECULAR-WEIGHT PROTEIN LYSOZYME AS A CARRIER FOR RENAL DRUG TARGETING.

Published in:

Renal Failure, 2001, v. 23, n. 3/4, p. 397, doi. 10.1081/JDI-100104723

By:

Haverdings, R. Folgert G.;
Haas, Marijke;
Greupink, A. Rick;
deVries, P. A. Marcel;
Moolenaar, Frits;
de Zeeuw, Dick;
Meijer, Dirk K. F.

Publication type:

Article

Getting the dose right using physiologically-based pharmacokinetic modeling: dexamethasone to prevent post-extubation stridor in children as proof of concept.

Published in:

Frontiers in Pediatrics, 2024, p. 1, doi. 10.3389/fped.2024.1416440

By:

van der Heijden, Joyce E. M.;
de Hoop-Sommen, Marika;
Hoevenaars, Noa;
Freriksen, Jolien J. M.;
Joosten, Koen;
Greupink, Rick;
de Wildt, Saskia N.

Publication type:

Article

Pragmatic physiologically-based pharmacokinetic modeling to support clinical implementation of optimized gentamicin dosing in term neonates and infants: proof-of-concept.

Published in:

Frontiers in Pediatrics, 2023, p. 1, doi. 10.3389/fped.2023.1288376

By:

de Hoop-Sommen, Marika A.;
van der Heijden, Joyce E. M.;
Freriksen, Jolien J. M.;
Greupink, Rick;
de Wildt, Saskia N.

Publication type:

Article

Assessment of Placental Disposition of Infliximab and Etanercept in Women With Autoimmune Diseases and in the Ex Vivo Perfused Placenta.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 1, p. 99, doi. 10.1002/cpt.1827

By:

Eliesen, Gaby A. M.;
van Drongelen, Joris;
van Hove, Hedwig;
Kooijman, Nina I.;
van den Broek, Petra;
de Vries, Annick;
Roeleveld, Nel;
Russel, Frans G. M.;
Greupink, Rick

Publication type:

Article

Assessment of Maternal and Fetal Dolutegravir Exposure by Integrating Ex Vivo Placental Perfusion Data and Physiologically‐Based Pharmacokinetic Modeling.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 6, p. 1352, doi. 10.1002/cpt.1748

By:

Freriksen, Jolien J.M.;
Schalkwijk, Stein;
Colbers, Angela P.;
Abduljalil, Khaled;
Russel, Frans G.M.;
Burger, David M.;
Greupink, Rick

Publication type:

Article

Placental disposition of eculizumab, C5 and C5‐eculizumab in two pregnancies of a woman with paroxysmal nocturnal haemoglobinuria.

Published in:

British Journal of Clinical Pharmacology, 2021, v. 87, n. 4, p. 2128, doi. 10.1111/bcp.14565

By:

Eliesen, Gaby A.M.;
Drongelen, Joris;
Broek, Petra H.H.;
Sarlea, Andrei;
Heijden, Olivier W.H.;
Langemeijer, Saskia;
Greupink, Rick;
Volokhina, Elena B.;
Russel, Frans G.M.

Publication type:

Article

Free dug concentrations in pregnancy: Bound to measure unbound?

Published in:

2017

By:

Schalkwijk, Stein;
Greupink, Rick;
Burger, David

Publication type:

Editorial

Targeting 15d-Prostaglandin J<sub>2</sub> to Hepatic Stellate Cells: Two Options Evaluated.

Published in:

Pharmaceutical Research, 2007, v. 24, n. 3, p. 566, doi. 10.1007/s11095-006-9175-2

By:

Werner Hagens;
Adriana Mattos;
Rick Greupink;
Alie de Jager-Krikken;
Catharina Reker-Smit;
AnneMiek van Loenen-Weemaes;
Annette Gouw;
Klaas Poelstra;
Leonie Beljaars

Publication type:

Article

Physiologically Based Pharmacokinetic (PBPK) Model-Informed Dosing Guidelines for Pediatric Clinical Care: A Pragmatic Approach for a Special Population.

Published in:

Pediatric Drugs, 2023, v. 25, n. 1, p. 5, doi. 10.1007/s40272-022-00535-w

By:

Freriksen, Jolien J. M.;
van der Heijden, Joyce E. M.;
de Hoop-Sommen, Marika A.;
Greupink, Rick;
de Wildt, Saskia N.

Publication type:

Article

Physiologically‐Based Pharmacokinetic Modeling for Drug Dosing in Pediatric Patients: A Tutorial for a Pragmatic Approach in Clinical Care.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 5, p. 960, doi. 10.1002/cpt.3023

By:

van der Heijden, Joyce E. M.;
Freriksen, Jolien J. M.;
de Hoop‐Sommen, Marika A.;
Greupink, Rick;
de Wildt, Saskia N.

Publication type:

Article

Placental Disposition and Effects of Crizotinib: An Ex Vivo Study in the Isolated Dual-Side Perfused Human Cotyledon.

Published in:

Toxicological Sciences, 2017, v. 157, n. 2, p. 500, doi. 10.1093/toxsci/kfx063

By:

Eliesen, Gaby A. M.;
van den Broek, Petra;
van den Heuvel, Jeroen J.;
Bilos, Albert;
Pertijs, Jeanne;
van Drongelen, Joris;
Russel, Frans G. M.;
Greupink, Rick

Publication type:

Article

Interaction of Digitalis-Like Compounds with P-Glycoprotein.

Published in:

Toxicological Sciences, 2013, v. 131, n. 2, p. 502, doi. 10.1093/toxsci/kfs307

By:

Gozalpour, Elnaz;
Wittgen, Hanneke G. M.;
van den Heuvel, Jeroen J. M. W.;
Greupink, Rick;
Russel, Frans G. M.;
Koenderink, Jan B.

Publication type:

Article

In Silico Identification of Potential Cholestasis-Inducing Agents via Modeling of Na+-Dependent Taurocholate Cotransporting Polypeptide Substrate Specificity.

Published in:

Toxicological Sciences, 2012, v. 129, n. 1, p. 35, doi. 10.1093/toxsci/kfs188

By:

Greupink, Rick;
Nabuurs, Sander B.;
Zarzycka, Barbara;
Verweij, Vivienne;
Monshouwer, Mario;
Huisman, Maarten T.;
Russel, Frans G. M.

Publication type:

Article

Towards More Robust Evaluation of the Predictive Performance of Physiologically Based Pharmacokinetic Models: Using Confidence Intervals to Support Use of Model-Informed Dosing in Clinical Care.

Published in:

Clinical Pharmacokinetics, 2024, v. 63, n. 3, p. 343, doi. 10.1007/s40262-023-01326-3

By:

van Borselen, Marjolein D.;
Sluijterman, Laurens Auke Æmiel;
Greupink, Rick;
de Wildt, Saskia N.

Publication type:

Article

Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care.

Published in:

Clinical Pharmacokinetics, 2022, v. 61, n. 12, p. 1705, doi. 10.1007/s40262-022-01181-8

By:

van der Heijden, Joyce E. M.;
Freriksen, Jolien J. M.;
de Hoop-Sommen, Marika A.;
van Bussel, Lianne P. M.;
Driessen, Sander H. P.;
Orlebeke, Anne E. M.;
Verscheijden, Laurens F. M.;
Greupink, Rick;
de Wildt, Saskia N.

Publication type:

Article

Pharmacokinetics of HIV-Integrase Inhibitors During Pregnancy: Mechanisms, Clinical Implications and Knowledge Gaps.

Published in:

2019

By:

van der Galiën, Ruben;
ter Heine, Rob;
Greupink, Rick;
Schalkwijk, Stein J.;
van Herwaarden, Antonius E.;
Colbers, Angela;
Burger, David M.

Publication type:

journal article

A Mechanism-Based Population Pharmacokinetic Analysis Assessing the Feasibility of Efavirenz Dose Reduction to 400 mg in Pregnant Women.

Published in:

2018

By:

Schalkwijk, Stein;
ter Heine, Rob;
Colbers, Angela C.;
Huitema, Alwin D. R.;
Denti, Paolo;
Dooley, Kelly E.;
Capparelli, Edmund;
Best, Brookie M.;
Cressey, Tim R.;
Greupink, Rick;
Russel, Frans G. M.;
Mirochnick, Mark;
Burger, David M.

Publication type:

journal article

Prediction of Fetal Darunavir Exposure by Integrating Human Ex-Vivo Placental Transfer and Physiologically Based Pharmacokinetic Modeling.

Published in:

2018

By:

Schalkwijk, Stein;
Buaben, Aaron O.;
Freriksen, Jolien J. M.;
Colbers, Angela P.;
Burger, David M.;
Greupink, Rick;
Russel, Frans G. M.

Publication type:

journal article

Physiologically Based Modelling of Darunavir/Ritonavir Pharmacokinetics During Pregnancy.

Published in:

2016

By:

Colbers, Angela;
Greupink, Rick;
Litjens, Carlijn;
Burger, David;
Russel, Frans;
Russel, Frans G M

Publication type:

journal article