Works by Greninger, Alexander


Results: 145
    1

    SIV/SARS-CoV-2 coinfection in rhesus macaques impacts viral shedding, host immunity, the microbiome, and viral evolution.

    Published in:
    Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1587688
    By:
    • Fredericks, Megan N.;
    • Kolodner, Zohar;
    • Waalkes, Adam;
    • Sawatzki, Kaitlin;
    • Hao, Linhui;
    • Long, Dustin R.;
    • Penewit, Kelsi;
    • Midkiff, Cecily C.;
    • McCormick, Carter J.;
    • Beraki, Semira;
    • Edlefsen, Paul T.;
    • Barrow, Jeana;
    • Greninger, Alexander L.;
    • Gale, Michael;
    • Blair, Robert V.;
    • Salipante, Stephen J.;
    • Fuller, Deborah H.;
    • O'Connor, Megan A.
    Publication type:
    Article
    2

    Real-Time Use of Monkeypox Virus Genomic Surveillance, King County, Washington, USA, 2022–2024.

    Published in:
    Emerging Infectious Diseases, 2025, v. 31, p. S76, doi. 10.3201/eid3113.241242
    By:
    • Lau, Kathryn M.;
    • Banks, Michaela;
    • Bryant, Kaila;
    • Lambert, Joanie D.;
    • Marcela Torres, Laura;
    • Lunn, Stephanie M.;
    • Yun, Cory;
    • Roychoudhury, Pavitra;
    • Nunley, B. Ethan;
    • Sereewit, Jaydee;
    • Greninger, Alexander L.;
    • Black, Allison;
    • Kawakami, Vance;
    • Pogosjans, Sargis;
    • Gonzales, Elysia;
    • Chow, Eric J.
    Publication type:
    Article
    3

    Outbreak Investigation of COVID-19 Among Residents and Staff of an Independent and Assisted Living Community for Older Adults in Seattle, Washington.

    Published in:
    2020
    By:
    • Roxby, Alison C.;
    • Greninger, Alexander L.;
    • Hatfield, Kelly M.;
    • Lynch, John B.;
    • Dellit, Timothy H.;
    • James, Allison;
    • Taylor, Joanne;
    • Page, Libby C.;
    • Kimball, Anne;
    • Arons, Melissa;
    • Munanga, Albert;
    • Stone, Nimalie;
    • Jernigan, John A.;
    • Reddy, Sujan C.;
    • Lewis, James;
    • Cohen, Seth A.;
    • Jerome, Keith R.;
    • Duchin, Jeffrey S.;
    • Neme, Santiago
    Publication type:
    journal article
    4
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    SYMPTOM AND VIRAL REBOUND IN UNTREATED COVID-19 INFECTION.

    Published in:
    Topics in Antiviral Medicine, 2023, v. 31, n. 2, p. 70
    By:
    • Deo, Rinki;
    • Choudhary, Manish C.;
    • Moser, Carlee;
    • Ritz, Justin;
    • Daar, Eric S.;
    • Wohl, David A.;
    • Greninger, Alexander L.;
    • Eron, Joseph J.;
    • Currier, Judith S.;
    • Hughes, Michael D.;
    • Smith, Davey M.;
    • Chew, Kara W.;
    • Li, Jonathan Z.
    Publication type:
    Article
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    Clinical and Genomic Epidemiology of Coxsackievirus A21 and Enterovirus D68 in Homeless Shelters, King County, Washington, USA, 2019-2021.

    Published in:
    Emerging Infectious Diseases, 2024, v. 30, n. 11, p. 2251, doi. 10.3201/eid3011.240687
    By:
    • Cox, Sarah N.;
    • Casto, Amanda M.;
    • Franko, Nicholas M.;
    • Chow, Eric J.;
    • Han, Peter D.;
    • Gamboa, Luis;
    • Pfau, Brian;
    • Hong Xie;
    • Kong, Kevin;
    • Sereewit, Jaydee;
    • Rolfes, Melissa A.;
    • Mosites, Emily;
    • Uyeki, Timothy M.;
    • Greninger, Alexander L.;
    • Carone, Marco;
    • Mia Shim, M.;
    • Bedford, Trevor;
    • Shendure, Jay;
    • Boeckh, Michael;
    • Englund, Janet A.
    Publication type:
    Article
    10
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    Human Parainfluenza Virus in Homeless Shelters before and during the COVID-19 Pandemic, Washington, USA.

    Published in:
    Emerging Infectious Diseases, 2022, v. 28, n. 11, p. 2343, doi. 10.3201/eid2811.221156
    By:
    • Chow, Eric J.;
    • Casto, Amanda M.;
    • Sampoleo, Reigran;
    • Mills, Margaret G.;
    • Han, Peter D.;
    • Hong Xie;
    • Pfau, Brian;
    • Nguyen, Tien V.;
    • Sereewit, Jaydee;
    • Rogers, Julia H.;
    • Cox, Sarah N.;
    • Rolfes, Melissa A.;
    • Ogokeh, Constance;
    • Mosites, Emily;
    • Uyeki, Timothy M.;
    • Greninger, Alexander L.;
    • Hughes, James P.;
    • Shim, M. Mia;
    • Sugg, Nancy;
    • Duchin, Jeffrey S.
    Publication type:
    Article
    13
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    Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step.

    Published in:
    PLoS Biology, 2020, v. 18, n. 10, p. 1, doi. 10.1371/journal.pbio.3000896
    By:
    • Bruce, Emily A.;
    • Huang, Meei-Li;
    • Perchetti, Garrett A.;
    • Tighe, Scott;
    • Laaguiby, Pheobe;
    • Hoffman, Jessica J.;
    • Gerrard, Diana L.;
    • Nalla, Arun K.;
    • Wei, Yulun;
    • Greninger, Alexander L.;
    • Diehl, Sean A.;
    • Shirley, David J.;
    • Leonard, Debra G. B.;
    • Huston, Christopher D.;
    • Kirkpatrick, Beth D.;
    • Dragon, Julie A.;
    • Crothers, Jessica W.;
    • Jerome, Keith R.;
    • Botten, Jason W.
    Publication type:
    Article
    15

    In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age.

    Published in:
    PLoS Biology, 2020, v. 18, n. 9, p. 1, doi. 10.1371/journal.pbio.3000849
    By:
    • Lieberman, Nicole A. P.;
    • Peddu, Vikas;
    • Xie, Hong;
    • Shrestha, Lasata;
    • Huang, Meei-Li;
    • Mears, Megan C.;
    • Cajimat, Maria N.;
    • Bente, Dennis A.;
    • Shi, Pei-Yong;
    • Bovier, Francesca;
    • Roychoudhury, Pavitra;
    • Jerome, Keith R.;
    • Moscona, Anne;
    • Porotto, Matteo;
    • Greninger, Alexander L.
    Publication type:
    Article
    16
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    Ocular Mpox in a Breastfeeding Healthcare Provider.

    Published in:
    Open Forum Infectious Diseases, 2024, v. 11, n. 6, p. 1, doi. 10.1093/ofid/ofae290
    By:
    • Lovett, Sara;
    • Griffith, Jayne;
    • Lehnertz, Nick;
    • Fox, Teresa;
    • Siwek, Greg;
    • Barnes, Aaron M T;
    • Kofman, Aaron D;
    • Hufstetler, Kaitlin;
    • Greninger, Alexander L;
    • Townsend, Michael B;
    • Carson, William C;
    • Lynfield, Ruth;
    • Cash-Goldwasser, Shama
    Publication type:
    Article
    19
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    SARS-CoV-2 Viral Load on Admission Is Associated With 30-Day Mortality.

    Published in:
    Open Forum Infectious Diseases, 2020, v. 7, n. 12, p. 1, doi. 10.1093/ofid/ofaa535
    By:
    • Bryan, Andrew;
    • Fink, Susan L;
    • Gattuso, Meghan A;
    • Pepper, Gregory;
    • Chaudhary, Anu;
    • Wener, Mark H;
    • Morishima, Chihiro;
    • Jerome, Keith R;
    • Mathias, Patrick C;
    • Greninger, Alexander L
    Publication type:
    Article
    22
    23

    Host–pathogen dynamics in longitudinal clinical specimens from patients with COVID-19.

    Published in:
    Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09752-2
    By:
    • Lin, Michelle J.;
    • Rachleff, Victoria M.;
    • Xie, Hong;
    • Shrestha, Lasata;
    • Lieberman, Nicole A. P.;
    • Peddu, Vikas;
    • Addetia, Amin;
    • Casto, Amanda M.;
    • Breit, Nathan;
    • Mathias, Patrick C.;
    • Huang, Meei-Li;
    • Jerome, Keith R.;
    • Greninger, Alexander L.;
    • Roychoudhury, Pavitra
    Publication type:
    Article
    24

    SARS-CoV-2 VOC type and biological sex affect molnupiravir efficacy in severe COVID-19 dwarf hamster model.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32045-1
    By:
    • Lieber, Carolin M.;
    • Cox, Robert M.;
    • Sourimant, Julien;
    • Wolf, Josef D.;
    • Juergens, Kate;
    • Phung, Quynh;
    • Saindane, Manohar T.;
    • Smith, Meghan K.;
    • Sticher, Zachary M.;
    • Kalykhalov, Alexander A.;
    • Natchus, Michael G.;
    • Painter, George R.;
    • Sakamoto, Kaori;
    • Greninger, Alexander L.;
    • Plemper, Richard K.
    Publication type:
    Article
    25

    De novo emergence of a remdesivir resistance mutation during treatment of persistent SARS-CoV-2 infection in an immunocompromised patient: a case report.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29104-y
    By:
    • Gandhi, Shiv;
    • Klein, Jonathan;
    • Robertson, Alexander J.;
    • Peña-Hernández, Mario A.;
    • Lin, Michelle J.;
    • Roychoudhury, Pavitra;
    • Lu, Peiwen;
    • Fournier, John;
    • Ferguson, David;
    • Mohamed Bakhash, Shah A. K.;
    • Catherine Muenker, M.;
    • Srivathsan, Ariktha;
    • Wunder Jr, Elsio A.;
    • Kerantzas, Nicholas;
    • Wang, Wenshuai;
    • Lindenbach, Brett;
    • Pyle, Anna;
    • Wilen, Craig B.;
    • Ogbuagu, Onyema;
    • Greninger, Alexander L.
    Publication type:
    Article
    26

    Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26760-4
    By:
    • Cox, Robert M.;
    • Wolf, Josef D.;
    • Lieber, Carolin M.;
    • Sourimant, Julien;
    • Lin, Michelle J.;
    • Babusis, Darius;
    • DuPont, Venice;
    • Chan, Julie;
    • Barrett, Kim T.;
    • Lye, Diane;
    • Kalla, Rao;
    • Chun, Kwon;
    • Mackman, Richard L.;
    • Ye, Chengjin;
    • Cihlar, Tomas;
    • Martinez-Sobrido, Luis;
    • Greninger, Alexander L.;
    • Bilello, John P.;
    • Plemper, Richard K.
    Publication type:
    Article
    27

    Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26096-z
    By:
    • Ferren, Marion;
    • Favède, Valérie;
    • Decimo, Didier;
    • Iampietro, Mathieu;
    • Lieberman, Nicole A. P.;
    • Weickert, Jean-Luc;
    • Pelissier, Rodolphe;
    • Mazelier, Magalie;
    • Terrier, Olivier;
    • Moscona, Anne;
    • Porotto, Matteo;
    • Greninger, Alexander L.;
    • Messaddeq, Nadia;
    • Horvat, Branka;
    • Mathieu, Cyrille
    Publication type:
    Article
    28

    Discovery of a Novel Polyomavirus in Acute Diarrheal Samples from Children.

    Published in:
    PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049449
    By:
    • Guixia Yu;
    • Greninger, Alexander L.;
    • Isa, Pavel;
    • Phan, Tung G.;
    • Martínez, Miguel Angel;
    • Sanchez, Maria de la Luz;
    • Contreras, Juan Francisco;
    • Santos-Preciado, José Ignacio;
    • Parsonnet, Julie;
    • Miller, Steve;
    • DeRisi, Joseph L.;
    • Delwart, Eric;
    • Arias, Carlos F.;
    • Chiu, Charles Y.
    Publication type:
    Article
    29
    30

    A human coronavirus evolves antigenically to escape antibody immunity.

    Published in:
    PLoS Pathogens, 2021, v. 17, n. 4, p. 1, doi. 10.1371/journal.ppat.1009453
    By:
    • Eguia, Rachel T.;
    • Crawford, Katharine H. D.;
    • Stevens-Ayers, Terry;
    • Kelnhofer-Millevolte, Laurel;
    • Greninger, Alexander L.;
    • Englund, Janet A.;
    • Boeckh, Michael J.;
    • Bloom, Jesse D.
    Publication type:
    Article
    31
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    Detection of SARS-CoV-2 Among Residents and Staff Members of an Independent and Assisted Living Community for Older Adults -- Seattle, Washington, 2020.

    Published in:
    MMWR: Morbidity & Mortality Weekly Report, 2020, v. 69, n. 14, p. 416, doi. 10.15585/mmwr.mm6914e2
    By:
    • Roxby, Alison C.;
    • Greninger, Alexander L.;
    • Hatfield, Kelly M.;
    • Lynch, John B.;
    • Dellit, Timothy H.;
    • James, Allison;
    • Taylor, Joanne;
    • Page, Libby C.;
    • Kimball, Anne;
    • Arons, Melissa;
    • Schieve, Laura A.;
    • Munanga, Albert;
    • Stone, Nimalie;
    • Jernigan, John A.;
    • Reddy, Sujan C.;
    • Lewis, James;
    • Cohen, Seth A.;
    • Jerome, Keith R.;
    • Duchin, Jeffrey S.;
    • Neme, Santiago
    Publication type:
    Article
    34

    Nebulized fusion inhibitory peptide protects cynomolgus macaques from measles virus infection.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33832-6
    By:
    • Reynard, Olivier;
    • Gonzalez, Claudia;
    • Dumont, Claire;
    • Iampietro, Mathieu;
    • Ferren, Marion;
    • Le Guellec, Sandrine;
    • Laurie, Lajoie;
    • Mathieu, Cyrille;
    • Carpentier, Gabrielle;
    • Roseau, Georges;
    • Bovier, Francesca T.;
    • Zhu, Yun;
    • Le Pennec, Deborah;
    • Montharu, Jérome;
    • Addetia, Amin;
    • Greninger, Alexander L.;
    • Alabi, Christopher A.;
    • Brisebard, Elise;
    • Moscona, Anne;
    • Vecellio, Laurent
    Publication type:
    Article
    35

    Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia.

    Published in:
    Science Translational Medicine, 2019, v. 11, n. 515, p. 1, doi. 10.1126/scitranslmed.aax5866
    By:
    • Toots, Mart;
    • Yoon, Jeong-Joong;
    • Cox, Robert M.;
    • Hart, Michael;
    • Sticher, Zachary M.;
    • Makhsous, Negar;
    • Plesker, Roland;
    • Barrena, Alec H.;
    • Reddy, Prabhakar G.;
    • Mitchell, Deborah G.;
    • Shean, Ryan C.;
    • Bluemling, Gregory R.;
    • Kolykhalov, Alexander A.;
    • Greninger, Alexander L.;
    • Natchus, Michael G.;
    • Painter, George R.;
    • Plemper, Richard K.
    Publication type:
    Article
    36
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    40

    Intranasally administrated fusion-inhibitory lipopeptides block SARS-CoV-2 infection in mice and enable long-term protective immunity.

    Published in:
    Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07491-4
    By:
    • Mougari, Said;
    • Favède, Valérie;
    • Predella, Camilla;
    • Reynard, Olivier;
    • Durand, Stephanie;
    • Mazelier, Magalie;
    • Pizzioli, Edoardo;
    • Decimo, Didier;
    • Bovier, Francesca T.;
    • Lapsley, Lauren M.;
    • Castagna, Candace;
    • Lieberman, Nicole A. P.;
    • Noel, Guillaume;
    • Mathieu, Cyrille;
    • Malissen, Bernard;
    • Briese, Thomas;
    • Greninger, Alexander L.;
    • Alabi, Christopher A.;
    • Dorrello, N. Valerio;
    • Marot, Stéphane
    Publication type:
    Article
    41

    Digital detection of endonuclease mediated gene disruption in the HIV provirus.

    Published in:
    Scientific Reports, 2016, p. 20064, doi. 10.1038/srep20064
    By:
    • Sedlak, Ruth Hall;
    • Liang, Shu;
    • Niyonzima, Nixon;
    • De Silva Feelixge, Harshana S.;
    • Roychoudhury, Pavitra;
    • Greninger, Alexander L.;
    • Weber, Nicholas D.;
    • Boissel, Sandrine;
    • Scharenberg, Andrew M.;
    • Cheng, Anqi;
    • Magaret, Amalia;
    • Bumgarner, Roger;
    • Stone, Daniel;
    • Jerome, Keith R.
    Publication type:
    Article
    42

    Symptom and Viral Rebound in Untreated SARS-CoV-2 Infection.

    Published in:
    Annals of Internal Medicine, 2023, v. 176, n. 3, p. 348, doi. 10.7326/M22-2381
    By:
    • Deo, Rinki;
    • Choudhary, Manish C.;
    • Moser, Carlee;
    • Ritz, Justin;
    • Daar, Eric S.;
    • Wohl, David A.;
    • Greninger, Alexander L.;
    • Eron, Joseph J.;
    • Currier, Judith S.;
    • Hughes, Michael D.;
    • Smith, Davey M.;
    • Chew, Kara W.;
    • Li, Jonathan Z.;
    • Javan, Arzhang Cyrus;
    • Giganti, Mark;
    • Hosey, Lara;
    • Roa, Jhoanna;
    • Patel, Nilam;
    • Colsh, Kelly;
    • Rwakazina, Irene
    Publication type:
    Article
    43
    44

    Safety and Efficacy of Combined Tixagevimab and Cilgavimab Administered Intramuscularly or Intravenously in Nonhospitalized Patients With COVID-19: 2 Randomized Clinical Trials.

    Published in:
    JAMA Network Open, 2023, v. 6, n. 4, p. e2310039, doi. 10.1001/jamanetworkopen.2023.10039
    By:
    • Bender Ignacio, Rachel A.;
    • Chew, Kara W.;
    • Moser, Carlee;
    • Currier, Judith S.;
    • Eron, Joseph J.;
    • Javan, Arzhang Cyrus;
    • Giganti, Mark J.;
    • Aga, Evgenia;
    • Gibbs, Michael;
    • Tchouakam Kouekam, Hervé;
    • Johnsson, Eva;
    • Esser, Mark T.;
    • Hoover, Keila;
    • Neytman, Gene;
    • Newell, Matthew;
    • Daar, Eric S.;
    • Fischer, William;
    • Fletcher, Courtney V.;
    • Li, Jonathan Z.;
    • Greninger, Alexander L.
    Publication type:
    Article
    45

    Safety, Immunogenicity, and Efficacy of the NVX-CoV2373 COVID-19 Vaccine in Adolescents: A Randomized Clinical Trial.

    Published in:
    JAMA Network Open, 2023, v. 6, n. 4, p. e239135, doi. 10.1001/jamanetworkopen.2023.9135
    By:
    • Áñez, Germán;
    • Dunkle, Lisa M.;
    • Gay, Cynthia L.;
    • Kotloff, Karen L.;
    • Adelglass, Jeffrey M.;
    • Essink, Brandon;
    • Campbell, James D.;
    • Cloney-Clark, Shane;
    • Zhu, Mingzhu;
    • Plested, Joyce S.;
    • Roychoudhury, Pavitra;
    • Greninger, Alexander L.;
    • Patel, Nita;
    • McGarry, Alice;
    • Woo, Wayne;
    • Cho, Iksung;
    • Glenn, Gregory M.;
    • Dubovsky, Filip
    Publication type:
    Article
    46
    47

    Immunocompromised Host Pneumonia: Definitions and Diagnostic Criteria: An Official American Thoracic Society Workshop Report.

    Published in:
    Annals of the American Thoracic Society, 2023, v. 20, n. 3, p. 341, doi. 10.1513/AnnalsATS.202212-1019ST
    By:
    • Guang-Shing Cheng;
    • Crothers, Kristina;
    • Aliberti, Stefano;
    • Bergeron, Anne;
    • Boeckh, Michael;
    • Chien, Jason W.;
    • Cilloniz, Catia;
    • Cohen, Keira;
    • Dean, Nathan;
    • Cruz, Charles S. Dela;
    • Dickson, Robert P.;
    • Greninger, Alexander L.;
    • Hage, Chadi A.;
    • Hohl, Tobias M.;
    • Holland, Steven M.;
    • Jones, Barbara E.;
    • Keane, Joseph;
    • Metersky, Mark;
    • Miller, Rachel;
    • Puel, Anne
    Publication type:
    Article
    48
    49

    In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19.

    Published in:
    Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83730-y
    By:
    • Phan, Isabelle Q.;
    • Subramanian, Sandhya;
    • Kim, David;
    • Murphy, Michael;
    • Pettie, Deleah;
    • Carter, Lauren;
    • Anishchenko, Ivan;
    • Barrett, Lynn K.;
    • Craig, Justin;
    • Tillery, Logan;
    • Shek, Roger;
    • Harrington, Whitney E.;
    • Koelle, David M.;
    • Wald, Anna;
    • Veesler, David;
    • King, Neil;
    • Boonyaratanakornkit, Jim;
    • Isoherranen, Nina;
    • Greninger, Alexander L.;
    • Jerome, Keith R.
    Publication type:
    Article
    50

    CrAssphage and its bacterial host in cat feces.

    Published in:
    Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80076-9
    By:
    • Li, Yanpeng;
    • Gordon, Emilia;
    • Shean, Ryan C.;
    • Idle, Amanda;
    • Deng, Xutao;
    • Greninger, Alexander L.;
    • Delwart, Eric
    Publication type:
    Article