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A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07620-7
By:
- Sorensen, Anders B.;
- Greisen, Per Jr.;
- Madsen, Jesper J.;
- Lund, Jacob;
- Andersen, Gorm;
- Wulff-Larsen, Pernille G.;
- Pedersen, Anette A.;
- Gandhi, Prafull S.;
- Overgaard, Michael T.;
- Østergaard, Henrik;
- Olsen, Ole H.
Publication type:
Article
Improvement of a synthetic live bacterial therapeutic for phenylketonuria with biosensor-enabled enzyme engineering.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26524-0
By:
- Adolfsen, Kristin J.;
- Callihan, Isolde;
- Monahan, Catherine E.;
- Greisen, Per Jr.;
- Spoonamore, James;
- Momin, Munira;
- Fitch, Lauren E.;
- Castillo, Mary Joan;
- Weng, Lindong;
- Renaud, Lauren;
- Weile, Carl J.;
- Konieczka, Jay H.;
- Mirabella, Teodelinda;
- Abin-Fuentes, Andres;
- Lawrence, Adam G.;
- Isabella, Vincent M.
Publication type:
Article
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23609-8
By:
- Hosseinzadeh, Parisa;
- Watson, Paris R.;
- Craven, Timothy W.;
- Li, Xinting;
- Rettie, Stephen;
- Pardo-Avila, Fátima;
- Bera, Asim K.;
- Mulligan, Vikram Khipple;
- Lu, Peilong;
- Ford, Alexander S.;
- Weitzner, Brian D.;
- Stewart, Lance J.;
- Moyer, Adam P.;
- Di Piazza, Maddalena;
- Whalen, Joshua G.;
- Greisen, Per Jr.;
- Christianson, David W.;
- Baker, David
Publication type:
Article
Multi-input chemical control of protein dimerization for programming graded cellular responses.
Published in:
Nature Biotechnology, 2019, v. 37, n. 10, p. 1209, doi. 10.1038/s41587-019-0242-8
By:
- Foight, Glenna Wink;
- Wang, Zhizhi;
- Wei, Cindy T.;
- Jr Greisen, Per;
- Warner, Katrina M.;
- Cunningham-Bryant, Daniel;
- Park, Keunwan;
- Brunette, T. J.;
- Sheffler, William;
- Baker, David;
- Maly, Dustin J.
Publication type:
Article
Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers.
Published in:
PEDS: Protein Engineering, Design & Selection, 2017, v. 30, n. 4, p. 333, doi. 10.1093/protein/gzx003
By:
- Goldsmith, Moshe;
- Aggarwal, Nidhi;
- Ashani, Yacov;
- Jubran, Halim;
- Greisen, Per Jr.;
- Ovchinnikov, Sergey;
- Leader, Haim;
- Baker, David;
- Sussman, Joel L.;
- Goldenzweig, Adi;
- Fleishman, Sarel J.;
- Tawfik, Dan S.
Publication type:
Article
Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis.
Published in:
Nature Chemical Biology, 2012, v. 8, n. 3, p. 294, doi. 10.1038/nchembio.777
By:
- Khare, Sagar D;
- Kipnis, Yakov;
- Greisen, Per Jr;
- Takeuchi, Ryo;
- Ashani, Yacov;
- Goldsmith, Moshe;
- Song, Yifan;
- Gallaher, Jasmine L;
- Silman, Israel;
- Leader, Haim;
- Sussman, Joel L;
- Stoddard, Barry L;
- Tawfik, Dan S;
- Baker, David
Publication type:
Article
Computational design of N‐linked glycans for high throughput epitope profiling.
Published in:
Protein Science: A Publication of the Protein Society, 2023, v. 32, n. 10, p. 1, doi. 10.1002/pro.4726
By:
- Greisen, Per Jr.;
- Yi, Li;
- Zhou, Rong;
- Zhou, Jian;
- Johansson, Eva;
- Dong, Tiantang;
- Liu, Haimo;
- Johnsen, Laust B.;
- Lund, Søren;
- Svensson, L. Anders;
- Zhu, Haisun;
- Thomas, Nidhin;
- Yang, Zhiru;
- Østergaard, Henrik
Publication type:
Article

Found: 7

A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa.

Improvement of a synthetic live bacterial therapeutic for phenylketonuria with biosensor-enabled enzyme engineering.

Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites.

Multi-input chemical control of protein dimerization for programming graded cellular responses.

Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers.

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis.

Computational design of N‐linked glycans for high throughput epitope profiling.