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The TICE Pathway: Mechanisms and Lipid-Lowering Therapies.
Published in:
Methodist DeBakey Cardiovascular Journal, 2019, v. 15, n. 1, p. 70, doi. 10.14797/mdcj-15-1-70
By:
- Grefhorst, Aldo;
- Verkade, Henkjan J.;
- Groen, Albert K.
Publication type:
Article
Physical Activity and Dietary Composition Relate to Differences in Gut Microbial Patterns in a Multi-Ethnic Cohort—The HELIUS Study.
Published in:
Metabolites (2218-1989), 2021, v. 11, n. 12, p. 858, doi. 10.3390/metabo11120858
By:
- Houttu, Veera;
- Boulund, Ulrika;
- Nicolaou, Mary;
- Holleboom, Adriaan Georgius;
- Grefhorst, Aldo;
- Galenkamp, Henrike;
- van den Born, Bert-Jan;
- Zwinderman, Koos;
- Nieuwdorp, Max
Publication type:
Article
Sex difference in thermal preference of adult mice does not depend on presence of the gonads.
Published in:
Biology of Sex Differences, 2017, v. 8, p. 1, doi. 10.1186/s13293-017-0145-7
By:
- Kaikaew, Kasiphak;
- Steenbergen, Jacobie;
- Themmen, Axel P. N.;
- Visser, Jenny A.;
- Grefhorst, Aldo
Publication type:
Article
Glucose Kinetics in the Collagen-Induced Arthritis Model: An All-in-One Model to Assess Both Efficacy and Metabolic Side Effects of Glucocorticoids.
Published in:
PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0098684
By:
- Toonen, Erik J. M.;
- Laskewitz, Anke J.;
- van Dijk, Theo H.;
- Bleeker, Aycha;
- Grefhorst, Aldo;
- Schouten, Annelies E.;
- Bastiaanssen, Ellen A. J.;
- Ballak, Dov B.;
- Koenders, Marije I.;
- van Doorn, Cindy;
- van der Vleuten, Monique A. J.;
- van Lierop, Marie-Jose C.;
- Groen, Albert K.;
- Dokter, Wim H. A.
Publication type:
Article
Unacylated Ghrelin Suppresses Grelin-Induced Neuronal Activity in the Hypothalamus and Brainstem of Male Rats.
Published in:
PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0098180
By:
- Stevanovic, Darko M.;
- Grefhorst, Aldo;
- Themmen, Axel P. N.;
- Popovic, Vera;
- Holstege, Joan;
- Haasdijk, Elize;
- Trajkovic, Vladimir;
- van der Lely, Aart-Jan;
- Delhanty, Patric J. D.
Publication type:
Article
Prospective study on blood pressure, lipid metabolism and erythrocytosis during and after androgen abuse.
Published in:
Andrologia, 2022, v. 54, n. 4, p. 1, doi. 10.1111/and.14372
By:
- Smit, Diederik L.;
- Grefhorst, Aldo;
- Buijs, Madelon M.;
- de Hon, Olivier;
- den Heijer, Martin;
- de Ronde, Willem
Publication type:
Article
Sex Difference in Corticosterone-Induced Insulin Resistance in Mice.
Published in:
Endocrinology, 2019, v. 160, n. 10, p. 2367, doi. 10.1210/en.2019-00194
By:
- Kaikaew, Kasiphak;
- Steenbergen, Jacobie;
- Dijk, Theo H van;
- Grefhorst, Aldo;
- Visser, Jenny A
Publication type:
Article
Sex Differences in Brown Adipose Tissue Function: Sex Hormones, Glucocorticoids, and Their Crosstalk.
Published in:
Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.652444
By:
- Kaikaew, Kasiphak;
- Grefhorst, Aldo;
- Visser, Jenny A.
Publication type:
Article
The Role of Lipophagy in the Development and Treatment of Non-Alcoholic Fatty Liver Disease.
Published in:
Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.601627
By:
- Grefhorst, Aldo;
- van de Peppel, Ivo P.;
- Larsen, Lars E.;
- Jonker, Johan W.;
- Holleboom, Adriaan G.
Publication type:
Article
A systems biology approach reveals the physiological origin of hepatic steatosis induced by liver X receptor activation.
Published in:
FASEB Journal, 2015, v. 29, n. 4, p. 1153, doi. 10.1096/fj.14-254656
By:
- Hijmans, Brenda S.;
- Tiemann, Christian A.;
- Grefhorst, Aldo;
- Boesjes, Marije;
- van Dijk, Theo H.;
- Tietge, Uwe J. F.;
- Kuipers, Folkert;
- van Riel, Natal A. W.;
- Groen, Albert K.;
- Oosterveer, Maaike H.
Publication type:
Article
Direct activating effects of adreno cortico tropic hormone (ACTH) on brown adipose tissue are attenuated by corticosterone.
Published in:
FASEB Journal, 2014, v. 28, n. 11, p. 4857, doi. 10.1096/fj.14-254839
By:
- van den Beukel, Johanna C.;
- Grefhorst, Aldo;
- Quarta, Carmelo;
- Steenbergen, Jacobie;
- Mastroberardino, Pier G.;
- Lombes, Marc;
- Delhanty, Patric J.;
- Mazza, Roberta;
- Pagotto, Uberto;
- van der Lely, Aart Jan;
- Themmen, Axel P. N.
Publication type:
Article
Des-acyl ghrelin analogs prevent high-fat-diet-induced dysregulation of glucose homeostasis.
Published in:
FASEB Journal, 2013, v. 27, n. 4, p. 1690, doi. 10.1096/fj.12-221143
By:
- Delhanty, Patric J. D.;
- Huisman, Martin;
- Baldeon-Rojas, Lucy Y.;
- van den Berge, Iris;
- Grefhorst, Aldo;
- Abribat, Thierry;
- Leenen, Pieter J. M.;
- Themmen, Axel P. N.;
- van der Lely, Aart-Jan
Publication type:
Article
Next-generation sequencing to confirmclinical familial hypercholesterolemia.
Published in:
European Journal of Preventive Cardiology, 2021, v. 28, n. 8, p. 875, doi. 10.1093/eurjpc/zwaa451
By:
- Reeskamp, Laurens F.;
- Tromp, Tycho R.;
- Defesche, Joep C.;
- Grefhorst, Aldo;
- Stroes, Erik S. G.;
- Hovingh, G. Kees;
- Zuurbier, Linda
Publication type:
Article
Ursodeoxycholic Acid for Trans Intestinal Cholesterol Excretion Stimulation: A Randomized Placebo Controlled Crossover Study.
Published in:
Journal of the American Heart Association, 2024, v. 13, n. 20, p. 1, doi. 10.1161/JAHA.124.035259
By:
- Oostveen, Reindert F.;
- Kaiser, Yannick;
- Hartgers, Merel L.;
- Meessen, Emma C. E.;
- Grefhorst, Aldo;
- Hovingh, G. Kees;
- Kuipers, Folkert;
- Stroes, Erik S. G.;
- Groen, Albert K.;
- Reeskamp, Laurens F.
Publication type:
Article
Peritoneal Dialysis Aggravates and Accelerates Atherosclerosis in Uremic ApoE<sup>-/-</sup> Mice.
Published in:
Journal of the American Heart Association, 2024, v. 13, n. 14, p. 1, doi. 10.1161/JAHA.123.034066
By:
- Kane, Jamie;
- Vos, Winnie G.;
- Bosmans, Laura A.;
- van Os, Bram W.;
- den Toom, Myrthe;
- Hackmann, Sanne Hoeksema;
- Moen-de Wit, Denise;
- Gijbels, Marion J.;
- Beckers, Linda;
- Grefhorst, Aldo;
- Levels, Johannes H. M.;
- Jakulj, Lily;
- Vervloet, Marc G.;
- Lutgens, Esther;
- Eringa, Etto C.
Publication type:
Article
ANGPTL3 (Angiopoietin-Like 3) Preferentially Resides on High-Density Lipoprotein in the Human Circulation, Affecting Its Activity.
Published in:
Journal of the American Heart Association, 2023, v. 12, n. 21, p. 1, doi. 10.1161/JAHA.123.030476
By:
- Kraaijenhof, Jordan M.;
- Tromp, Tycho R.;
- Nurmohamed, Nick S.;
- Reeskamp, Laurens F.;
- Langenkamp, Marije;
- Levels, Johannes H. M.;
- Boekholdt, S. Matthijs;
- Wareham, Nicholas J.;
- Hoekstra, Menno;
- Stroes, Erik S. G.;
- Hovingh, G. Kees;
- Grefhorst, Aldo
Publication type:
Article
Estrogens increase expression of bone morphogenetic protein 8b in brown adipose tissue of mice.
Published in:
Biology of Sex Differences, 2015, v. 6, n. 1, p. 1, doi. 10.1186/s13293-015-0025-y
By:
- Grefhorst, Aldo;
- van den Beukel, Johanna C.;
- van Houten, E. Leonie A. F.;
- Steenbergen, Jacobie;
- Visser, Jenny A.;
- Themmen, Axel P. N.
Publication type:
Article
Long-Chain Fatty Acid Oxidation Is Not Essential to Drive Gluconeogenesis in Short Term Fasted Male CB57BL/6J Mice In Vivo.
Published in:
Diabetes, 2007, v. 56, p. A391
By:
- Van Dijk, Theo H.;
- Derks, Terry G.;
- Grefhorst, Aldo;
- Smit, G. Peter A.;
- Havinga, Rick;
- Kuipers, Folkert;
- Reijngoud, Dirk-Jan
Publication type:
Article
Hepatic Glucose-6-Phosphate Metabolism Is Perturbed in LXR-Alpha Null Mice.
Published in:
Diabetes, 2007, v. 56, p. A39
By:
- Oosterveer, Maaike H.;
- Van Dijk, Theo H.;
- Grefhorst, Aldo;
- Havinga, Rick;
- Kuipers, Folkert;
- Reijngoud, Dirk-Jan
Publication type:
Article
Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity.
Published in:
Diabetes, 2007, v. 56, n. 5, p. 1341, doi. 10.2337/db06-1619
By:
- Aerts, Johannes M.;
- Ottenhoff, Roelof;
- Powlson, Andrew S.;
- Grefhorst, Aldo;
- Eijk, Marco van;
- Dubbelhuis, Peter F.;
- Aten, Jan;
- Kuipers, Folkert;
- Serlie, Mireille J.;
- Wennekes, Tom;
- Sethi, Jaswinder K.;
- O'Rahilly, Stephen;
- Overkleeft, Hermen S.
Publication type:
Article
Does aerobic exercise reduce NASH and liver fibrosis in patients with non-alcoholic fatty liver disease? A systematic literature review and meta-analysis.
Published in:
Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.1032164
By:
- Houttu, Veera;
- Bouts, Julia;
- Vali, Yasaman;
- Daams, Joost;
- Grefhorst, Aldo;
- Nieuwdorp, Max;
- Holleboom, Adriaan G.
Publication type:
Article
The role of the gut microbiome and exercise in non-alcoholic fatty liver disease.
Published in:
Therapeutic Advances in Gastroenterology, 2020, v. 13, p. 1, doi. 10.1177/1756284820941745
By:
- Houttu, Veera;
- Boulund, Ulrika;
- Grefhorst, Aldo;
- Soeters, Maarten R.;
- Pinto-Sietsma, Sara-Joan;
- Nieuwdorp, Max;
- Holleboom, Adriaan G.
Publication type:
Article
Transient impairment of the adaptive response to fasting in FXR-deficient mice
Published in:
FEBS Letters, 2005, v. 579, n. 19, p. 4076, doi. 10.1016/j.febslet.2005.06.033
By:
- Cariou, Bertrand;
- van Harmelen, Kirsten;
- Duran-Sandoval, Daniel;
- van Dijk, Theo;
- Grefhorst, Aldo;
- Bouchaert, Emmanuel;
- Fruchart, Jean-Charles;
- Gonzalez, Frank J.;
- Kuipers, Folkert;
- Staels, Bart
Publication type:
Article
Anaerobutyricum soehngenii Reduces Hepatic Lipogenic Pathways and Increases Intestinal Gluconeogenic Gene Expression in Metabolic-Dysfunction-Associated Steatotic Liver Disease (MASLD) Mice.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 6, p. 3481, doi. 10.3390/ijms25063481
By:
- Mak, Anne Linde;
- Augustijn, Quinten J. J.;
- Heymann, Clément J. F.;
- Havik, Stefan;
- Verdoes, Xanthe;
- Rios-Morales, Melany;
- Bosmans, Laura A.;
- Verheij, Joanne;
- Meijnikman, Abraham S.;
- de Jonge, Patrick A.;
- Herrema, Hilde;
- de Vos, Willem M.;
- Nieuwdorp, Max;
- Grefhorst, Aldo;
- Holleboom, Adriaan G.
Publication type:
Article
Women have more potential to induce browning of perirenal adipose tissue than men.
Published in:
Obesity (19307381), 2015, v. 23, n. 8, p. 1671, doi. 10.1002/oby.21166
By:
- van den Beukel, Johanna C.;
- Grefhorst, Aldo;
- Hoogduijn, Martin J.;
- Steenbergen, Jacobie;
- Mastroberardino, Pier G.;
- Dor, Frank J.M.F.;
- Themmen, Axel P.N.
Publication type:
Article
Severe Dyslipidemia Mimicking Familial Hypercholesterolemia Induced by High-Fat, Low-Carbohydrate Diets: A Critical Review.
Published in:
Nutrients, 2023, v. 15, n. 4, p. 962, doi. 10.3390/nu15040962
By:
- Houttu, Veera;
- Grefhorst, Aldo;
- Cohn, Danny M.;
- Levels, Johannes H. M.;
- Roeters van Lennep, Jeanine;
- Stroes, Erik S. G.;
- Groen, Albert K.;
- Tromp, Tycho R.
Publication type:
Article
The role of the gut microbiome and exercise in non-alcoholic fatty liver disease.
Published in:
Therapeutic Advances in Gastroenterology, 2020, v. 13, p. 1, doi. 10.1177/1756284820941745
By:
- Houttu, Veera;
- Boulund, Ulrika;
- Grefhorst, Aldo;
- Soeters, Maarten R.;
- Pinto-Sietsma, Sara-Joan;
- Nieuwdorp, Max;
- Holleboom, Adriaan G.
Publication type:
Article

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