Works by Greene, Nicholas D. E.

Results: 40

Rho GTPases in mammalian spinal neural tube closure.

Published in:

Small GTPases, 2018, v. 9, n. 4, p. 283, doi. 10.1080/21541248.2016.1235388

By:

Rolo, Ana;
Escuin, Sarah;
Greene, Nicholas D. E.;
Copp, Andrew J.

Publication type:

Article

Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non‐ketotic hyperglycinemia.

Published in:

Journal of Inherited Metabolic Disease, 2020, v. 43, n. 6, p. 1186, doi. 10.1002/jimd.12295

By:

Leung, Kit‐Yi;
De Castro, Sandra C. P.;
Santos, Chloe;
Savery, Dawn;
Prunty, Helen;
Gold‐Diaz, Diana;
Bennett, Stuart;
Heales, Simon;
Copp, Andrew J.;
Greene, Nicholas D. E.

Publication type:

Article

Aberrant methylation of Pax3 gene and neural tube defects in association with exposure to polycyclic aromatic hydrocarbons.

Published in:

Clinical Epigenetics, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13148-019-0611-7

By:

Lin, Shanshan;
Ren, Aiguo;
Wang, Linlin;
Santos, Chloe;
Huang, Yun;
Jin, Lei;
Li, Zhiwen;
Greene, Nicholas D. E.

Publication type:

Article

Genetic interaction of Pax3 mutation and canonical Wnt signaling modulates neural tube defects and neural crest abnormalities.

Published in:

Genesis: The Journal of Genetics & Development, 2021, v. 59, n. 11, p. 1, doi. 10.1002/dvg.23445

By:

Palmer, Alexandra J.;
Savery, Dawn;
Massa, Valentina;
Copp, Andrew J.;
Greene, Nicholas D. E.

Publication type:

Article

Dolutegravir and rat whole embryo culture.

Published in:

Birth Defects Research, 2022, v. 114, n. 1, p. 23, doi. 10.1002/bdr2.1969

By:

Copp, Andrew J.;
Greene, Nicholas D. E.;
Jao, Jennifer;
Zash, Rebecca;
Mohan, Haneesha;
Dontsova, Valeriya;
Serghides, Lena

Publication type:

Article

Refinement of inducible gene deletion in embryos of pregnant mice.

Published in:

Birth Defects Research, 2020, v. 112, n. 2, p. 196, doi. 10.1002/bdr2.1628

By:

Savery, Dawn;
Maniou, Eirini;
Culshaw, Lucy H.;
Greene, Nicholas D. E.;
Copp, Andrew J.;
Galea, Gabriel L.

Publication type:

Article

Dynamic acetylation profile during mammalian neurulation.

Published in:

Birth Defects Research, 2020, v. 112, n. 2, p. 205, doi. 10.1002/bdr2.1618

By:

Massa, Valentina;
Avagliano, Laura;
Grazioli, Paolo;
De Castro, Sandra C. P.;
Parodi, Chiara;
Savery, Dawn;
Vergani, Patrizia;
Cuttin, Serena;
Doi, Patrizia;
Bulfamante, Gaetano;
Copp, Andrew J.;
Greene, Nicholas D. E.

Publication type:

Article

Mouse whole embryo culture: Evaluating the requirement for rat serum as culture medium.

Published in:

Birth Defects Research, 2019, v. 111, n. 16, p. 1165, doi. 10.1002/bdr2.1538

By:

Culshaw, Lucy H.;
Savery, Dawn;
Greene, Nicholas D. E.;
Copp, Andrew J.

Publication type:

Article

A non-coding insertional mutation of Grhl2 causes gene over-expression and multiple structural anomalies including cleft palate, spina bifida and encephalocele.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 17, p. 2681, doi. 10.1093/hmg/ddad094

By:

Crane-Smith, Zoe;
Castro, Sandra C P De;
Nikolopoulou, Evanthia;
Wolujewicz, Paul;
Smedley, Damian;
Lei, Yunping;
Mather, Emma;
Santos, Chloe;
Hopkinson, Mark;
Pitsillides, Andrew A;
Consortium, Genomics England Research;
Finnell, Richard H;
Ross, M Elisabeth;
Copp, Andrew J;
Greene, Nicholas D E

Publication type:

Article

An update on the use of inositols in preventing gestational diabetes mellitus (GDM) and neural tube defects (NTDs).

Published in:

Expert Opinion on Drug Metabolism & Toxicology, 2020, v. 16, n. 12, p. 1187, doi. 10.1080/17425255.2020.1828344

By:

Facchinetti, Fabio;
Cavalli, Pietro;
Copp, Andrew J.;
D'Anna, Rosario;
Kandaraki, Eleni;
Greene, Nicholas D. E.;
Unfer, Vittorio

Publication type:

Article

Neural tube defects-disorders of neurulation and related embryonic processes.

Published in:

WIREs: Developmental Biology, 2013, v. 2, n. 2, p. 213, doi. 10.1002/wdev.71

By:

Copp, Andrew J.;
Greene, Nicholas D. E.

Publication type:

Article

Abnormal folate metabolism in foetuses affected by neural tube defects.

Published in:

2007

By:

Dunlevy LPE;
Chitty LS;
Burren KA;
Doudney K;
Stojilkovic-Mikic T;
Stanier P;
Scott R;
Copp AJ;
Greene NDE;
Dunlevy, Louisa P E;
Chitty, Lyn S;
Burren, Katie A;
Doudney, Kit;
Stojilkovic-Mikic, Taita;
Stanier, Philip;
Scott, Rosemary;
Copp, Andrew J;
Greene, Nicholas D E

Publication type:

journal article

Abnormal folate metabolism in foetuses affected by neural tube defects.

Published in:

Brain: A Journal of Neurology, 2007, v. 130, n. 4, p. 1043

By:

Louisa P. E. Dunlevy;
Lyn S. Chitty;
Katie A. Burren;
Kit Doudney;
Taita Stojilkovic-Mikic;
Philip Stanier;
Rosemary Scott;
Andrew J. Copp;
Nicholas D. E. Greene

Publication type:

Article

Development of the vertebrate central nervous system: formation of the neural tube.

Published in:

Prenatal Diagnosis, 2009, v. 29, n. 4, p. 303, doi. 10.1002/pd.2206

By:

Greene, Nicholas D. E.;
Copp, Andrew J.

Publication type:

Article

Non-Isolated Neural Tube Defects with Comorbid Malformations Are Responsive to Population-Level Folic Acid Supplementation in Northern China.

Published in:

Biology (2079-7737), 2022, v. 11, n. 9, p. 1371, doi. 10.3390/biology11091371

By:

Che, Xiaoyu;
Liu, Jufen;
Galea, Gabriel L;
Zhang, Yali;
Greene, Nicholas D. E.;
Zhang, Le;
Jin, Lei;
Wang, Linlin;
Ren, Aiguo;
Li, Zhiwen

Publication type:

Article

The arginine methyltransferase Carm1 is necessary for heart development.

Published in:

G3: Genes | Genomes | Genetics, 2022, v. 12, n. 8, p. 1, doi. 10.1093/g3journal/jkac155

By:

Jamet, Sophie;
Seungshin Ha;
Tzu-Hua Ho;
Houghtaling, Scott;
Timms, Andrew;
Kai Yu;
Paquette, Alison;
Maga, Ali Murat;
Greene, Nicholas D. E.;
Beier, David R.

Publication type:

Article

Microtubules, polarity and vertebrate neural tube morphogenesis.

Published in:

Journal of Anatomy, 2016, v. 229, n. 1, p. 63, doi. 10.1111/joa.12468

By:

Cearns, Michael D.;
Escuin, Sarah;
Alexandre, Paula;
Greene, Nicholas D. E.;
Copp, Andrew J.

Publication type:

Article

Proteome changes associated with hippocampal MRI abnormalities in the lithium pilocarpine-induced model of convulsive status epilepticus.

Published in:

Proteomics, 2007, v. 7, n. 8, p. 1336, doi. 10.1002/pmic.200601027

By:

Greene, Nicholas D. E.;
Bamidele, Abiodun;
Choy, ManKin;
de Castro, Sandra C. P.;
Wait, Robin;
Leung, Kit-Yi;
Begum, Shajna;
Gadian, David G.;
Scott, Rod C.;
Lythgoe, Mark F.

Publication type:

Article

Could microRNAs be biomarkers for neural tube defects?

Published in:

Journal of Neurochemistry, 2012, v. 122, n. 3, p. 485, doi. 10.1111/j.1471-4159.2012.07800.x

By:

Greene, Nicholas D. E.;
Copp, Andrew J.

Publication type:

Article

The actions of methotrexate on endothelial cells are dependent on the shear stress-induced regulation of one carbon metabolism.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1209490

By:

Lang, Marie B.;
Kit-Yi Leung;
Greene, Nicholas D. E.;
Malone, Kerri M.;
Saginc, Gaye;
Randi, Anna M.;
Kiprianos, Allan;
Maughan, Robert T.;
Pericleous, Charis;
Mason, Justin C.

Publication type:

Article

Glycine Cleavage System H Protein Is Essential for Embryonic Viability, Implying Additional Function Beyond the Glycine Cleavage System.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2021.625120

By:

Leung, Kit-Yi;
De Castro, Sandra C. P.;
Galea, Gabriel L.;
Copp, Andrew J.;
Greene, Nicholas D. E.

Publication type:

Article

High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 5, p. 888, doi. 10.1093/hmg/ddx004

By:

Bahous, Renata H.;
Jadavji, Nafisa M.;
Deng, Liyuan;
Cosín-Tomás, Marta;
Lu, Jessica;
Malysheva, Olga;
Kit-Yi Leung;
Ming-Kai Ho;
Pallás, Mercè;
Kaliman, Perla;
Greene, Nicholas D. E.;
Bedell, Barry J.;
Caudill, Marie A.;
Rozen, Rima

Publication type:

Article

Deficient or Excess Folic Acid Supply During Pregnancy Alter Cortical Neurodevelopment in Mouse Offspring.

Published in:

Cerebral Cortex, 2021, v. 31, n. 1, p. 635, doi. 10.1093/cercor/bhaa248

By:

Crescenzo, Angelo Harlan De;
Panoutsopoulos, Alexios A;
Tat, Lyvin;
Schaaf, Zachary;
Racherla, Shailaja;
Henderson, Lyle;
Leung, Kit-Yi;
Greene, Nicholas D E;
Green, Ralph;
Zarbalis, Konstantinos S

Publication type:

Article

Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21372-4

By:

Galea, Gabriel L.;
Maniou, Eirini;
Edwards, Timothy J.;
Marshall, Abigail R.;
Ampartzidis, Ioakeim;
Greene, Nicholas D. E.;
Copp, Andrew J.

Publication type:

Article

Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14785-0

By:

Essmann, Clara L.;
Martinez-Martinez, Daniel;
Pryor, Rosina;
Leung, Kit-Yi;
Krishnan, Kalaivani Bala;
Lui, Prudence Pokway;
Greene, Nicholas D. E.;
Brown, André E. X.;
Pawar, Vijay M.;
Srinivasan, Mandayam A.;
Cabreiro, Filipe

Publication type:

Article

Lamin B1 Polymorphism Influences Morphology of the Nuclear Envelope, Cell Cycle Progression, and Risk of Neural Tube Defects in Mice.

Published in:

PLoS Genetics, 2012, v. 8, n. 11, p. 1, doi. 10.1371/journal.pgen.1003059

By:

De Castro, Sandra C. P.;
Malhas, Ashraf;
Kit-Yi Leung;
Gustavsson, Peter;
Vaux, David J.;
Copp, Andrew J.;
Greene, Nicholas D. E.

Publication type:

Article

D-chiro-inositol is more effective than myo-inositol in preventing folate-resistant mouse neural tube defects.

Published in:

2002

By:

Cogram, Patricia;
Tesh, Sheila;
Tesh, John;
Wade, Angie;
Allan, Geoffrey;
Greene, Nicholas D. E.;
Copp, Andrew J.

Publication type:

journal article

Regulation of cell protrusions by small GTPases during fusion of the neural folds.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.13273

By:

Rolo, Ana;
Savery, Dawn;
Escuin, Sarah;
de Castro, Sandra C.;
Armer, Hannah E. J.;
Munro, Peter M. G.;
Molè, Matteo A.;
Greene, Nicholas D. E.;
Copp, Andrew J.

Publication type:

Article

Eph and Ephrin Variants in Malaysian Neural Tube Defect Families.

Published in:

Genes, 2022, v. 13, n. 6, p. 952, doi. 10.3390/genes13060952

By:

Mohd-Zin, Siti Waheeda;
Tan, Amelia Cheng Wei;
Atroosh, Wahib M.;
Thong, Meow-Keong;
Azizi, Abu Bakar;
Greene, Nicholas D. E.;
Abdul-Aziz, Noraishah Mydin

Publication type:

Article

Abstracts of papers presented at the 29<sup>th</sup> Genetic Society's Mammalian Genetics and Development Workshop held at the UCL Great Ormond Street Institute of Child Health, University College London on Thursday 29<sup>th</sup> November 2018.

Published in:

Genetics Research, 2019, v. 101, p. N.PAG, doi. 10.1017/S0016672319000016

By:

Greene, Nicholas D. E.;
Copp, Andrew J.;
Andoniadou, Cynthia L.;
Cannavo, Claudia;
Cleverley, K.;
Tosh, J. L.;
Noy, S.;
Lana-Elola, E.;
Tybulewicz, V.;
Fisher, E. M. C.;
Wiseman, F. K.;
Calderon, Lesly;
Weiss, Felix D;
Carroll, Thomas;
Irvine, Elaine E.;
Dharmalingam, Gopuraja;
Tossell, Kyoko;
De Paola, Vincenzo;
Whilding, Chad;
Ungless, Mark A.

Publication type:

Article

Abstracts of papers presented at the 25th Genetics Society's Mammalian Genetics and Development Workshop held at the Institute of Child Health, University College London on 7th November 2014.

Published in:

Genetics Research, 2015, v. 97, p. N.PAG, doi. 10.1017/S0016672314000214

By:

GREENE, NICHOLAS D. E.;
WARD, ANDREW;
COPP, ANDREW J.

Publication type:

Article

Abstracts of papers presented at the 23rd Genetics Society's Mammalian Genetics and Development Workshop held at the Institute of Child Health, University College London on 22nd November 2012.

Published in:

Genetics Research, 2012, v. 94, n. 6, p. 353, doi. 10.1017/S0016672312000572

By:

GREENE, NICHOLAS D. E.;
COPP, ANDREW J.

Publication type:

Article

Abstracts of papers presented at the 21st Genetics Society's Mammalian Genetics and Development Workshop held at the Institute of Child Health, University College London on 11 November 2010.

Published in:

Genetics Research, 2011, v. 93, n. 6, p. 433, doi. 10.1017/S0016672311000383

By:

GREENE, NICHOLAS D. E.;
COPP, ANDREW J.;
WARD, ANDREW

Publication type:

Article

Abstracts of papers presented at the seventeenth Genetics Society's Mammalian Genetics and Development Workshop held at the Institute of Child Health, University College London on 9 and 10 November 2006.

Published in:

Genetics Research, 2007, v. 89, p. 181, doi. 10.1017/S0016672307008804

By:

COPP, ANDREW J.;
GREENE, NICHOLAS D.??E.;
FISHER, ELIZABETH M.??C.

Publication type:

Article

Author Correction: Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice.

Published in:

2021

By:

Galea, Gabriel L.;
Maniou, Eirini;
Edwards, Timothy J.;
Marshall, Abigail R.;
Ampartzidis, Ioakeim;
Greene, Nicholas D. E.;
Copp, Andrew J.

Publication type:

Correction Notice

Do cells become homeless during neural tube closure?

Published in:

Cell Cycle, 2009, v. 8, n. 16, p. 2479, doi. 10.4161/cc.8.16.9272

By:

Massa, Valentina;
Greene, Nicholas D. E.;
Copp, Andrew J.

Publication type:

Article

DHFR2 RNA directly regulates dihydrofolate reductase and its expression level impacts folate one carbon metabolism.

Published in:

FASEB Journal, 2025, v. 39, n. 4, p. 1, doi. 10.1096/fj.202401039RR

By:

Drago, Paola;
Bookey, Niamh;
Leung, Kit‐Yi;
Henry, Michael;
Meleady, Paula;
Greene, Nicholas D. E.;
Parle‐McDermott, Anne

Publication type:

Article

Association of embryonic inositol status with susceptibility to neural tube defects, metabolite profile, and maternal inositol intake.

Published in:

FASEB Journal, 2024, v. 38, n. 11, p. 1, doi. 10.1096/fj.202400206R

By:

Leung, Kit‐Yi;
Weston, Eleanor;
De Castro, Sandra C. P.;
Nikolopoulou, Evanthia;
Sudiwala, Sonia;
Savery, Dawn;
Eaton, Simon;
Copp, Andrew J.;
Greene, Nicholas D. E.

Publication type:

Article

Both the folate cycle and betaine-homocysteine methyltransferase contribute methyl groups for DNA methylation in mouse blastocysts.

Published in:

FASEB Journal, 2015, v. 29, n. 3, p. 1069, doi. 10.1096/fj.14-261131

By:

Baohua Zhang;
Denomme, Michelle M.;
White, Carlee R.;
Kit-Yi Leung;
Lee, Martin B.;
Greene, Nicholas D. E.;
Mann, Mellissa R. W.;
Trasler, Jacquetta M.;
Baltz, Jay M.

Publication type:

Article

Impaired folate 1-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase-deficient mice.

Published in:

2020

By:

Santos, Chloe;
Yun Jin Pai;
Mahmood, M. Raasib;
Kit-Yi Leung;
Savery, Dawn;
Waddington, Simon N.;
Copp, Andrew J.;
Greene, Nicholas D. E.;
Pai, Yun Jin;
Leung, Kit-Yi;
Greene, Nicholas DE

Publication type:

journal article