Works by Green, Douglas R

Results: 128

The DNA-binding domain mediates both nuclear and cytosolic functions of p53.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 6, p. 535, doi. 10.1038/nsmb.2829

By:

Follis, Ariele Viacava;
Llambi, Fabien;
Ou, Li;
Baran, Katherine;
Green, Douglas R;
Kriwacki, Richard W

Publication type:

Article

BID-induced structural changes in BAK promote apoptosis.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 5, p. 589, doi. 10.1038/nsmb.2563

By:

Moldoveanu, Tudor;
Grace, Christy R;
Llambi, Fabien;
Nourse, Amanda;
Fitzgerald, Patrick;
Gehring, Kalle;
Kriwacki, Richard W;
Green, Douglas R

Publication type:

Article

Autoreactivity and self-tolerance in an invertebrate.

Published in:

Nature, 1985, v. 313, n. 6001, p. 400, doi. 10.1038/313400a0

By:

Buss, Leo W.;
Moore, Jane L.;
Green, Douglas R.

Publication type:

Article

Mechanisms of TNF-independent RIPK3-mediated cell death.

Published in:

Biochemical Journal, 2022, v. 479, n. 19, p. 2040, doi. 10.1042/BCJ20210724

By:

Tummers, Bart;
Green, Douglas R.

Publication type:

Article

Immunogenic and tolerogenic cell death.

Published in:

2009

By:

Green, Douglas R.;
Ferguson, Thomas;
Zitvogel, Laurence;
Kroemer, Guido

Publication type:

journal article

Rubicon-deficiency sensitizes mice to mixed lineage kinase domain-like (MLKL)-mediated kidney ischemia-reperfusion injury.

Published in:

Cell Death & Disease, 2022, v. 13, n. 3, p. 1, doi. 10.1038/s41419-022-04682-3

By:

Tonnus, Wulf;
Locke, Sophie;
Meyer, Claudia;
Maremonti, Francesca;
Eggert, Lena;
von Mässenhausen, Anne;
Bornstein, Stefan R.;
Green, Douglas R.;
Linkermann, Andreas

Publication type:

Article

Apoptosis therapy: driving cancers down the road to ruin.

Published in:

Nature Medicine, 2013, v. 19, n. 2, p. 131, doi. 10.1038/nm.3076

By:

Green, Douglas R.;
Walczak, Henning

Publication type:

Article

Death receptors bind SHP-1 and block cytokine-induced anti-apoptotic signaling in neutrophils.

Published in:

Nature Medicine, 2002, v. 8, n. 1, p. 61, doi. 10.1038/nm0102-61

By:

Daigle, Isabelle;
Yousefi, Shida;
Colonna, Marco;
Green, Douglas R.;
Simon, Hans-Uwe

Publication type:

Article

T cells are just dying to accept grafts.

Published in:

Nature Medicine, 1999, v. 5, n. 11, p. 1231, doi. 10.1038/15180

By:

Ferguson, Thomas A.;
Green, Douglas R.

Publication type:

Article

PB1-F2 Proteins from H5N1 and 20th Century Pandemic Influenza Viruses Cause Immunopathology.

Published in:

PLoS Pathogens, 2010, v. 6, n. 7, p. 1, doi. 10.1371/journal.ppat.1001014

By:

McAuley, Julie L.;
Chipuk, Jerry E.;
Boyd, Kelli L.;
Van De Velde, Nick;
Green, Douglas R.;
McCullers, Jonathan A.

Publication type:

Article

HYPERIMMUNITY AND THE DECISION TO BE INTOLERANT *.

Published in:

Annals of the New York Academy of Sciences, 1982, v. 392, n. 1, p. 318, doi. 10.1111/j.1749-6632.1982.tb36117.x

By:

Green, Douglas R.;
Gershon, Richard K.

Publication type:

Article

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection.

Published in:

Nature Immunology, 2013, v. 14, n. 5, p. 480, doi. 10.1038/ni.2563

By:

Lupfer, Christopher;
Thomas, Paul G;
Anand, Paras K;
Vogel, Peter;
Milasta, Sandra;
Martinez, Jennifer;
Huang, Gonghua;
Green, Maggie;
Kundu, Mondira;
Chi, Hongbo;
Xavier, Ramnik J;
Green, Douglas R;
Lamkanfi, Mohamed;
Dinarello, Charles A;
Doherty, Peter C;
Kanneganti, Thirumala-Devi

Publication type:

Article

Metabolic checkpoints in activated T cells.

Published in:

Nature Immunology, 2012, v. 13, n. 10, p. 907, doi. 10.1038/ni.2386

By:

Wang, Ruoning;
Green, Douglas R

Publication type:

Article

Defective Dock2 expression in a subset of ASC-deficient mouse lines.

Published in:

Nature Immunology, 2012, v. 13, n. 7, p. 701, doi. 10.1038/ni.2389

By:

Ippagunta, Sirish K;
Malireddi, R K Subbarao;
Shaw, Patrick J;
Neale, Geoffrey A;
Walle, Lieselotte Vande;
Fukui, Yoshinori;
Green, Douglas R;
Lamkanfi, Mohamed;
Kanneganti, Thirumala-Devi

Publication type:

Article

The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization.

Published in:

Nature Immunology, 2011, v. 12, n. 10, p. 1010, doi. 10.1038/ni.2095

By:

Ippagunta, Sirish K;
Malireddi, R K Subbarao;
Shaw, Patrick J;
Neale, Geoffrey A;
Walle, Lieselotte Vande;
Green, Douglas R;
Fukui, Yoshinori;
Lamkanfi, Mohamed;
Kanneganti, Thirumala-Devi

Publication type:

Article

The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.

Published in:

Nature Immunology, 2011, v. 12, n. 9, p. 888, doi. 10.1038/ni.2068

By:

Yang, Kai;
Neale, Geoffrey;
Green, Douglas R;
He, Weifeng;
Chi, Hongbo

Publication type:

Article

Dynamic programming of CD8+ T lymphocyte responses.

Published in:

Nature Immunology, 2003, v. 4, n. 4, p. 361, doi. 10.1038/ni912

By:

van Stipdonk, Marianne J.B.;
Hardenberg, Gijs;
Bijker, Martijn S.;
Lemmens, Edward E.;
Droin, Nathalie M.;
Green, Douglas R.;
Schoenberger, Stephen P.

Publication type:

Article

The suicide in the thymus, a twisted trail.

Published in:

Nature Immunology, 2003, v. 4, n. 3, p. 207, doi. 10.1038/ni0303-207

By:

Green, Douglas R.

Publication type:

Article

Granzyme A: the road less traveled.

Published in:

Nature Immunology, 2003, v. 4, n. 2, p. 106, doi. 10.1038/ni0203-106

By:

Pinkoski, Michael J.;
Green, Douglas R.

Publication type:

Article

Murder by proxy.

Published in:

Nature Immunology, 2000, v. 1, n. 6, p. 461, doi. 10.1038/82701

By:

Pinkoski, Michael J.;
Green, Douglas R.

Publication type:

Article

T cell development: Some cells get all the breaks.

Published in:

Nature Immunology, 2000, v. 1, n. 1, p. 15, doi. 10.1038/76868

By:

Green, Douglas R.;
Schuler, Martin

Publication type:

Article

Loss of receptor interacting protein kinases 3 and caspase‐8 augments intrinsic apoptosis in tubular epithelial cell and promote kidney ischaemia‐reperfusion injury.

Published in:

Nephrology, 2019, v. 24, n. 6, p. 661, doi. 10.1111/nep.13487

By:

Sung, Baekjun;
Su, Ye;
Jiang, Jifu;
Mcleod, Patrick;
Liu, Weihua;
Haig, Aaron;
Green, Douglas R;
Zhang, Zhu‐Xu;
Jevnikar, Anthony M

Publication type:

Article

The evolution of a mechanism of cell suicide.

Published in:

BioEssays, 1999, v. 21, n. 1, p. 84, doi. 10.1002/(SICI)1521-1878(199901)21:1<84::AID-BIES11>3.0.CO;2-0

By:

Blackstone, Neil W.;
Green, Douglas R.

Publication type:

Article

Molecular definitions of autophagy and related processes.

Published in:

EMBO Journal, 2017, v. 36, n. 13, p. 1811, doi. 10.15252/embj.201796697

By:

Galluzzi, Lorenzo;
Baehrecke, Eric H;
Ballabio, Andrea;
Boya, Patricia;
Bravo‐San Pedro, José Manuel;
Cecconi, Francesco;
Choi, Augustine M;
Chu, Charleen T;
Codogno, Patrice;
Colombo, Maria Isabel;
Cuervo, Ana Maria;
Debnath, Jayanta;
Deretic, Vojo;
Dikic, Ivan;
Eskelinen, Eeva‐Liisa;
Fimia, Gian Maria;
Fulda, Simone;
Gewirtz, David A;
Green, Douglas R;
Hansen, Malene

Publication type:

Article

Dynamic metabolic reprogramming in dendritic cells: An early response to influenza infection that is essential for effector function.

Published in:

PLoS Pathogens, 2020, v. 16, n. 10, p. 1, doi. 10.1371/journal.ppat.1008957

By:

Rezinciuc, Svetlana;
Bezavada, Lavanya;
Bahadoran, Azadeh;
Duan, Susu;
Wang, Ruoning;
Lopez-Ferrer, Daniel;
Finkelstein, David;
McGargill, Maureen A.;
Green, Douglas R.;
Pasa-Tolic, Ljiljana;
Smallwood, Heather S.

Publication type:

Article

Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses.

Published in:

Science Translational Medicine, 2019, v. 11, n. 498, p. N.PAG, doi. 10.1126/scitranslmed.aat8549

By:

Zamora, Anthony E.;
Crawford, Jeremy Chase;
Allen, E. Kaitlynn;
Guo, Xi-zhi J.;
Bakke, Jesse;
Carter, Robert A.;
Abdelsamed, Hossa;
Moustaki, Ardiana;
Li, Yongjin;
Chang, Ti-Cheng;
Awad, Walid;
Dallas, Mari H.;
Mullighan, Charles G.;
Downing, James R.;
Geiger, Terrence L.;
Chen, Taosheng;
Green, Douglas R.;
Youngblood, Benjamin A.;
Zhang, Jinghui;
Thomas, Paul G.

Publication type:

Article

The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway.

Published in:

Autophagy, 2018, v. 14, n. 5, p. 796, doi. 10.1080/15548627.2017.1386820

By:

Wang, Bo;
Iyengar, Rekha;
Li-Harms, Xiujie;
Joo, Joung Hyuck;
Wright, Christopher;
Lavado, Alfonso;
Horner, Linda;
Yang, Mao;
Guan, Jun-Lin;
Frase, Sharon;
Green, Douglas R.;
Cao, Xinwei;
Kundu, Mondira

Publication type:

Article

Pharmacological manipulation of cell death: clinical applications in sight?

Published in:

Journal of Clinical Investigation, 2005, v. 115, n. 10, p. 2610, doi. 10.1172/JCI26321

By:

Green, Douglas R.;
Kroemer, Guido

Publication type:

Article

Regulation of apoptosis by oncogenes.

Published in:

Journal of Cellular Biochemistry, 1996, v. 60, n. 1, p. 33, doi. 10.1002/(SICI)1097-4644(19960101)60:1<33::AID-JCB6>3.0.CO;2-4

By:

Green, Douglas R.;
McGahon, Anne;
Martin, Seamus J.

Publication type:

Article

To the edge of cell death and back.

Published in:

FEBS Journal, 2019, v. 286, n. 3, p. 430, doi. 10.1111/febs.14714

By:

Gong, Yi‐Nan;
Crawford, Jeremy Chase;
Heckmann, Bradlee L.;
Green, Douglas R.

Publication type:

Article

MK-STYX, a Catalytically Inactive Phosphatase Regulating Mitochondrially Dependent Apoptosis.

Published in:

Molecular & Cellular Biology, 2011, v. 31, n. 7, p. 1357, doi. 10.1128/MCB.00788-10

By:

Niemi, Natalie M.;
Lanning, Nathan J.;
Klomp, Jeff A.;
Tait, Stephen W.;
Yong Xu;
Dykema, Karl J.;
Murphy, Leon O.;
Gaither, L. Alex;
Xu, H. Eric;
Furge, Kyle A.;
Green, Douglas R.;
MacKeigan, Jeffrey P.

Publication type:

Article

Immunometabolism at the crossroads of obesity and cancer—a Keystone Symposia report.

Published in:

Annals of the New York Academy of Sciences, 2023, v. 1523, n. 1, p. 38, doi. 10.1111/nyas.14976

By:

Cable, Jennifer;
Rathmell, Jeffrey C.;
Pearce, Erika L.;
Ho, Ping‐Chih;
Haigis, Marcia C.;
Mamedov, Murad R.;
Wu, Meng‐Ju;
Kaech, Susan M.;
Lynch, Lydia;
Febbraio, Mark A.;
Bapat, Sagar P.;
Hong, Hanna S.;
Zou, Weiping;
Belkaid, Yasmine;
Sullivan, Zuri A.;
Keller, Andrea;
Wculek, Stefanie K.;
Green, Douglas R.;
Postic, Catherine;
Amit, Ido

Publication type:

Article

Death deceiver.

Published in:

Nature, 1998, v. 396, n. 6712, p. 629, doi. 10.1038/25248

By:

Green, Douglas R.

Publication type:

Article

Another face of RIPK1.

Published in:

EMBO Reports, 2015, v. 16, n. 6, p. 674, doi. 10.15252/embr.201540470

By:

Green, Douglas R

Publication type:

Article

p53-dependent radiation-induced crypt intestinal epithelial cells apoptosis is mediated in part through TNF-TNFR1 system.

Published in:

Oncogene, 2001, v. 20, n. 7, p. 812, doi. 10.1038/sj.onc.1204172

By:

Inagaki-Ohara, Kyoko;
Yada, Shinichiro;
Takamura, Noriaki;
Reaves, Miriam;
Yu, Xiaohong;
Liu, Erdong;
Rooney, Isabelle;
Nicholas, Shelby;
Castro, Arturo;
Ware, Carl F;
Green, Douglas R;
Lin, Tesu

Publication type:

Article

Bcl-2-independent Bcr–Abl-mediated resistance to apoptosis: protection is correlated with up regulation of Bcl-xL.

Published in:

Oncogene, 1998, v. 16, n. 11, p. 1383, doi. 10.1038/sj.onc.1201664

By:

Amarante-Mendes, Gustavo P;
McGahon, Anne J;
Nishioka, Walter K;
Afar, Daniel EH;
Witte, Owen N;
Green, Douglas R

Publication type:

Article

Immunoregulatory circuits which modulate responsiveness to suppressor cell signals: characterization of an effector cell in the contrasuppressor circuit.

Published in:

European Journal of Immunology, 1981, v. 11, n. 12, p. 973, doi. 10.1002/eji.1830111205

By:

Green, Douglas R.;
Eardley, Diane D.;
Kimura, Art;
Murphy, Donal B.;
Yamauchi, Katsumi;
Gershon, Richard K.

Publication type:

Article

Immunoregulatory circuits which modulate responsiveness to suppressor cell signals: contrasuppressor cells can convert an in vivo tolerogenic signal into an immunogenic one.

Published in:

European Journal of Immunology, 1981, v. 11, n. 12, p. 980, doi. 10.1002/eji.1830111206

By:

Ptak, Wlodzimierz;
Green, Douglas R.;
Durum, Scott K.;
Kimura, Art;
Murphy, Donal B.;
Gershon, Richard K.

Publication type:

Article

Biological events and molecular signaling following MLKL activation during necroptosis.

Published in:

Cell Cycle, 2017, v. 16, n. 19, p. 1748, doi. 10.1080/15384101.2017.1371889

By:

Gong, Yi-Nan;
Guy, Cliff;
Crawford, Jeremy Chase;
Green, Douglas R.

Publication type:

Article

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

Published in:

EMBO Journal, 1998, v. 17, n. 1, p. 37, doi. 10.1093/emboj/17.1.37

By:

Bossy-Wetzel, Ella;
Newmeyer, Donald D.;
Green, Douglas R.

Publication type:

Article

Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system.

Published in:

EMBO Journal, 1997, v. 16, n. 15, p. 4639, doi. 10.1093/emboj/16.15.4639

By:

Kluck, Ruth M.;
Martin, Seamus J.;
Hoffman, Brian M.;
Zhou, Jian S.;
Green, Douglas R.;
Newmeyer, Donald D.

Publication type:

Article

Egr Family Members Regulate Nonlymphoid Expression of Fas Ligand, TRAIL, and Tumor Necrosis Factor during Immune Responses.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 21, p. 7638, doi. 10.1128/MCB.23.21.7638-7647.2003

By:

Droin, Nathalie M.;
Pinkoski, Michael J.;
Dejardin, Emmanuel;
Green, Douglas R.

Publication type:

Article

Differential requirements for myeloid leukemia IFN-γ conditioning determine graft-versus-leukemia resistance and sensitivity.

Published in:

2017

By:

Matte-Martone, Catherine;
Jinling Liu;
Meng Zhou;
Chikina, Maria;
Green, Douglas R.;
Harty, John T.;
Shlomchik, Warren D.;
Liu, Jinling;
Zhou, Meng

Publication type:

journal article

T Cell-Derived Antigen Binding Molecules (TABM): Molecular and Functional Properties.

Published in:

International Reviews of Immunology, 1988, v. 3, n. 3, p. 205, doi. 10.3109/08830188809051189

By:

Cone, Robert E.;
Zheng, Heguang;
Chue, Ben;
Beaman, Kenneth;
Ferguson, Thomas;
Green, Douglas R.

Publication type:

Article

Cell death and the immune system: getting to how and why.

Published in:

Immunological Reviews, 2017, v. 277, n. 1, p. 4, doi. 10.1111/imr.12553

By:

Green, Douglas R.

Publication type:

Article

Caspase-8: regulating life and death.

Published in:

Immunological Reviews, 2017, v. 277, n. 1, p. 76, doi. 10.1111/imr.12541

By:

Tummers, Bart;
Green, Douglas R.

Publication type:

Article

Metabolic reprogramming and metabolic dependency in T cells.

Published in:

Immunological Reviews, 2012, v. 249, n. 1, p. 14, doi. 10.1111/j.1600-065X.2012.01155.x

By:

Wang, Ruoning;
Green, Douglas R.

Publication type:

Article

Armed response: how dying cells influence T-cell functions.

Published in:

Immunological Reviews, 2011, v. 241, n. 1, p. 77, doi. 10.1111/j.1600-065X.2011.01006.x

By:

Ferguson, Thomas A.;
Choi, Jayoung;
Green, Douglas R.

Publication type:

Article

Toll-like receptor signaling in the lysosomal pathways.

Published in:

Immunological Reviews, 2009, v. 227, n. 1, p. 203, doi. 10.1111/j.1600-065X.2008.00732.x

By:

Sanjuan, Miguel A.;
Milasta, Sandra;
Green, Douglas R.

Publication type:

Article

Overview: apoptotic signaling pathways in the immune system.

Published in:

Immunological Reviews, 2003, v. 193, n. 1, p. 5, doi. 10.1034/j.1600-065X.2003.00045.x

By:

Green, Douglas R.

Publication type:

Article