Works by Gray, Nora E.

Results: 35

α -klotho as a biomarker of amyloid β levels in the cerebrospinal fluid.

Published in:

Frontiers in Aging Neuroscience, 2025, p. 1, doi. 10.3389/fnagi.2025.1599402

By:

Raber, Jacob;
Pederson, Alexandra;
Bunnell, Emily;
Mattek, Nora;
Gray, Nora E.;
Kohama, Steven G.;
Weiss, Alison R.;
Quinn, Joseph F.;
Urbanski, Henryk F.

Publication type:

Article

Integration of mass spectral fingerprinting analysis with precursor ion (MS1) quantification for the characterisation of botanical extracts: application to extracts of Centella asiatica (L.) Urban.

Published in:

Phytochemical Analysis, 2020, v. 31, n. 6, p. 722, doi. 10.1002/pca.2936

By:

Alcazar Magana, Armando;
Wright, Kirsten;
Vaswani, Ashish;
Caruso, Maya;
Reed, Ralph L.;
Bailey, Conner F.;
Nguyen, Thuan;
Gray, Nora E.;
Soumyanath, Amala;
Quinn, Joseph;
Stevens, Jan F.;
Maier, Claudia S.

Publication type:

Article

Withania somnifera (Ashwagandha) Improves Spatial Memory, Anxiety and Depressive-like Behavior in the 5xFAD Mouse Model of Alzheimer's Disease.

Published in:

Antioxidants, 2024, v. 13, n. 10, p. 1164, doi. 10.3390/antiox13101164

By:

Gladen-Kolarsky, Noah;
Monestime, Olivia;
Bollen, Melissa;
Choi, Jaewoo;
Yang, Liping;
Magaña, Armando Alcazar;
Maier, Claudia S.;
Soumyanath, Amala;
Gray, Nora E.

Publication type:

Article

Age-Associated DNA Methylation Patterns Are Shared Between the Hippocampus and Peripheral Blood Cells.

Published in:

Frontiers in Genetics, 2020, v. 11, p. 1, doi. 10.3389/fgene.2020.00111

By:

Harris, Christopher J.;
Davis, Brett A.;
Zweig, Jonathan A.;
Nevonen, Kimberly A.;
Quinn, Joseph F.;
Carbone, Lucia;
Gray, Nora E.

Publication type:

Article

Amelioration of age-related cognitive decline and anxiety in mice by Centella asiatica extract varies by sex, dose and mode of administration.

Published in:

Frontiers in Aging Neuroscience, 2024, p. 01, doi. 10.3389/fragi.2024.1357922

By:

Gray, Nora E.;
Hack, Wyatt;
Brandes, Mikah S.;
Zweig, Jonathan A.;
Liping Yang;
Marney, Luke;
Jaewoo Choi;
Magana, Armando Alcazar;
Cerruti, Natasha;
McFerrin, Janis;
Seiji Koike;
Thuan Nguyen;
Raber, Jacob;
Quinn, Joseph F.;
Maier, Claudia S.;
Soumyanath, Amala

Publication type:

Article

The Role of the NRF2 Pathway in Maintaining and Improving Cognitive Function.

Published in:

Biomedicines, 2022, v. 10, n. 8, p. N.PAG, doi. 10.3390/biomedicines10082043

By:

Gray, Nora E.;
Farina, Marcelo;
Tucci, Paolo;
Saso, Luciano

Publication type:

Article

Multi-Omics Analysis in Mouse Primary Cortical Neurons Reveals Complex Positive and Negative Biological Interactions Between Constituent Compounds of Centella asiatica.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 1, p. 19, doi. 10.3390/ph18010019

By:

Chamberlin, Steven R.;
Zweig, Jonathan A.;
Neff, Cody J.;
Marney, Luke;
Choi, Jaewoo;
Yang, Liping;
Maier, Claudia S.;
Soumyanath, Amala;
McWeeney, Shannon;
Gray, Nora E.

Publication type:

Article

Centella asiatica Promotes Antioxidant Gene Expression and Mitochondrial Oxidative Respiration in Experimental Autoimmune Encephalomyelitis.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 12, p. 1681, doi. 10.3390/ph17121681

By:

Kundu, Payel;
Yasuhara, Kanon;
Brandes, Mikah S.;
Zweig, Jonathan A.;
Neff, Cody J.;
Holden, Sarah;
Kessler, Kat;
Matsumoto, Steven;
Offner, Halina;
Waslo, Carin S.;
Vandenbark, Arthur;
Soumyanath, Amala;
Sherman, Larry S.;
Raber, Jacob;
Gray, Nora E.;
Spain, Rebecca I.

Publication type:

Article

Angiopoietin-like 4 (Angptl4) A glucocorticoid-dependent gatekeeper of fatty acid flux during fasting.

Published in:

Adipocyte, 2012, v. 1, n. 3, p. 182, doi. 10.4161/adip.20787

By:

Koliwad, Suneil K.;
Gray, Nora E.;
Wang, Jen-Chywan

Publication type:

Article

Centella asiatica Alters Metabolic Pathways Associated With Alzheimer's Disease in the 5xFAD Mouse Model of ß -Amyloid Accumulation.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.788312

By:

Speers, Alex B.;
García-Jaramillo, Manuel;
Feryn, Alicia;
Matthews, Donald G.;
Lichtenberg, Talia;
Caruso, Maya;
Wright, Kirsten M.;
Quinn, Joseph F.;
Stevens, Jan F.;
Maier, Claudia S.;
Soumyanath, Amala;
Gray, Nora E.

Publication type:

Article

Centella asiatica Attenuates Mitochondrial Dysfunction and Oxidative Stress in Aβ-Exposed Hippocampal Neurons.

Published in:

Oxidative Medicine & Cellular Longevity, 2017, p. 1, doi. 10.1155/2017/7023091

By:

Gray, Nora E.;
Zweig, Jonathan A.;
Matthews, Donald G.;
Caruso, Maya;
Quinn, Joseph F.;
Soumyanath, Amala

Publication type:

Article

Peripheral Blood DNA Methylation Changes in Response to Centella asiatica Treatment in Aged Mice.

Published in:

Biology (2079-7737), 2025, v. 14, n. 1, p. 52, doi. 10.3390/biology14010052

By:

Monestime, Olivia;
Davis, Brett A.;
Layman, Cora;
Wheeler, Kandace J.;
Hack, Wyatt;
Zweig, Jonathan A.;
Soumyanath, Amala;
Carbone, Lucia;
Gray, Nora E.

Publication type:

Article

Oral Asiatic Acid Improves Cognitive Function and Modulates Antioxidant and Mitochondrial Pathways in Female 5xFAD Mice.

Published in:

Nutrients, 2025, v. 17, n. 4, p. 729, doi. 10.3390/nu17040729

By:

Varada, Samantha;
Chamberlin, Stephen R.;
Bui, Lillie;
Brandes, Mikah S.;
Gladen-Kolarsky, Noah;
Harris, Christopher J.;
Hack, Wyatt;
Neff, Cody J.;
Brumbach, Barbara H.;
Soumyanath, Amala;
Quinn, Joseph F.;
Gray, Nora E.

Publication type:

Article

Caffeoylquinic Acids in Centella asiatica Reverse Cognitive Deficits in Male 5XFAD Alzheimer's Disease Model Mice.

Published in:

Nutrients, 2020, v. 12, n. 11, p. 3488, doi. 10.3390/nu12113488

By:

Matthews, Donald G.;
Caruso, Maya;
Alcazar Magana, Armando;
Wright, Kirsten M.;
Maier, Claudia S.;
Stevens, Jan F.;
Gray, Nora E.;
Quinn, Joseph F.;
Soumyanath, Amala

Publication type:

Article

Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella asiatica Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized Clinical Trial.

Published in:

Antioxidants, 2022, v. 11, n. 2, p. 215, doi. 10.3390/antiox11020215

By:

Wright, Kirsten M.;
Bollen, Melissa;
David, Jason;
Speers, Alex B.;
Brandes, Mikah S.;
Gray, Nora E.;
Alcázar Magaña, Armando;
McClure, Christine;
Stevens, Jan F.;
Maier, Claudia S.;
Quinn, Joseph F.;
Soumyanath, Amala

Publication type:

Article

NRF2 Activation Ameliorates Oxidative Stress and Improves Mitochondrial Function and Synaptic Plasticity, and in A53T α-Synuclein Hippocampal Neurons.

Published in:

Antioxidants, 2022, v. 11, n. 1, p. 26, doi. 10.3390/antiox11010026

By:

Brandes, Mikah S.;
Zweig, Jonathan A.;
Tang, Anita;
Gray, Nora E.

Publication type:

Article

Peripheral Blood NRF2 Expression as a Biomarker in Human Health and Disease.

Published in:

Antioxidants, 2021, v. 10, n. 1, p. 28, doi. 10.3390/antiox10010028

By:

Neilson, Lee E.;
Quinn, Joseph F.;
Gray, Nora E.

Publication type:

Article

Centella Asiatica Improves Memory and Promotes Antioxidative Signaling in 5XFAD Mice.

Published in:

Antioxidants, 2019, v. 8, n. 12, p. 630, doi. 10.3390/antiox8120630

By:

Matthews, Donald G;
Caruso, Maya;
Murchison, Charles F;
Zhu, Jennifer Y;
Wright, Kirsten M;
Harris, Christopher J;
Gray, Nora E;
Quinn, Joseph F;
Soumyanath, Amala

Publication type:

Article

Centella asiatica and its caffeoylquinic acid and triterpene constituents increase dendritic arborization of mouse primary hippocampal neurons and improve age-related locomotion deficits in Drosophila.

Published in:

Frontiers in Endocrinology, 2024, p. 1, doi. 10.3389/fragi.2024.1374905

By:

Rowe, Karon;
Gray, Nora E.;
Zweig, Jonathan A.;
Law, Alexander;
Techen, Natascha;
Maier, Claudia S.;
Soumyanath, Amala;
Kretzschmar, Doris

Publication type:

Article

Editorial: Plant-derived natural products: towards novel interventions for neurodegenerative diseases.

Published in:

Frontiers in Neuroscience, 2024, p. 01, doi. 10.3389/fnins.2024.1422351

By:

Alza, Natalia P.;
Salvador, Gabriela A.;
Gray, Nora E.;
Kaur, Ginpreet

Publication type:

Article

Mode of administration influences plasma levels of active Centella asiatica compounds in 5xFAD mice while markers of neuroinflammation remain unaltered.

Published in:

Frontiers in Neuroscience, 2024, p. 1, doi. 10.3389/fnins.2024.1277626

By:

Speers, Alex B.;
Wright, Kirsten M.;
Brandes, Mikah S.;
Kedjejian, Nareg;
Matthews, Donald G.;
Caruso, Maya;
Harris, Christopher J.;
Seiji Koike;
Thuan Nguyen;
Quinn, Joseph F.;
Soumyanath, Amala;
Gray, Nora E.

Publication type:

Article

The CD74 inhibitor DRhQ improves short-term memory and mitochondrial function in 5xFAD mouse model of Aβ accumulation.

Published in:

Metabolic Brain Disease, 2025, v. 40, n. 1, p. 1, doi. 10.1007/s11011-024-01433-5

By:

Gladen-Kolarsky, Noah;
Neff, Cody J.;
Hack, Wyatt;
Brandes, Mikah S.;
Wiedrick, Jack;
Meza-Romero, Roberto;
Lockwood, Denesa R.;
Quinn, Joseph F.;
Offner, Halina;
Vandenbark, Arthur A.;
Gray, Nora E.

Publication type:

Article

Centella asiatica increases hippocampal synaptic density and improves memory and executive function in aged mice.

Published in:

Brain & Behavior, 2018, v. 8, n. 7, p. 1, doi. 10.1002/brb3.1024

By:

Gray, Nora E.;
Zweig, Jonathan A.;
Caruso, Maya;
Martin, Marjoen D.;
Zhu, Jennifer Y.;
Quinn, Joseph F.;
Soumyanath, Amala

Publication type:

Article

DRhQ: a novel therapeutic that improves cognition and mitochondrial function and reduces neuroinflammation in beta‐amyloid overexpressing Mice.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072159

By:

Gray, Nora E;
Lockwood, Denesa R;
Hack, Wyatt E;
Brandes, Mikah S;
Meza‐Romero, Robert E;
Neff, Cody E;
Gladen‐Kolarsky, Noah E;
Quinn, Joseph F;
Vandenbark, Arthur A

Publication type:

Article

Investigating the effects of centella asiatica on neuroinflammation in beta‐amyloid overexpressing mice.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.064289

By:

Speers, Alex B;
Brandes, Mikah S;
Kedjejian, Nareg E;
Matthews, Donald G;
Caruso, Maya;
Wright, Kirsten M;
Quinn, Joseph F;
Soumyanath, Amala;
Gray, Nora E

Publication type:

Article

Asiatic improves brain mitochondrial function, activates antioxidant response and attenuates cognitive deficits in beta amyloid overexpressing mice.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.062432

By:

Gray, Nora E;
Chamberlin, Steven R;
Bui, Lillie E;
Brandes, Mikah S;
Brumbach, Barbara H;
Quinn, Joseph F

Publication type:

Article

From source to bedside: Translational studies of centella asiatica for Alzheimer's disease: Human/Human trials: Other.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041268

By:

Wright, Kirsten M.;
Magana, Armando Alcazar;
Bollen, Melissa;
Caruso, Maya;
Gray, Nora E.;
Matthews, Donald G;
David, Jason C.;
Mepham, Brigitte;
Stevens, Jan F.;
Maier, Claudia S.;
Quinn, Joseph F.;
Soumyanath, Amala

Publication type:

Article

P1‐084: CENTELLA ASIATICA IMPROVES MEMORY IN TG2576 AND 5XFAD MICE WITH GENDER‐DEPENDENT DIFFERENCES IN DOSE RESPONSE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P303, doi. 10.1016/j.jalz.2018.06.086

By:

Matthews, Donald G.;
Caruso, Maya;
Gray, Nora E.;
Zhu, Jennifer Y.;
Wright, Kirsten M.;
Quinn, Joseph F.;
Soumyanath, Amala

Publication type:

Article

URSODEOXYCHOLIC ACID FOR THE TREATMENT OF TAUOPATHIES.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1270, doi. 10.1016/j.jalz.2017.06.1902

By:

Quinn, Joseph F.;
Harris, Christopher;
Gray, Carly;
Debarber, Andrea;
Gray, Nora E.;
Matthews, Don;
Caruso, Maya;
Soumyanath, Amala

Publication type:

Article

CENTELLA ASIATICA ATTENUATES Aβ-INDUCED OXIDATIVE DAMAGE AND MITOCHONDRIAL DYSFUNCTION AND RESTORES SYNAPTIC PLASTICITY IN HIPPOCAMPAL NEURONS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P672, doi. 10.1016/j.jalz.2017.06.824

By:

Gray, Nora E.;
Zweig, Jonathan A.;
Kawamoto, Colleen;
Quinn, Joseph F.;
Soumyanath, Amala

Publication type:

Article

EXPLORING THE EFFECT OF CENTELLA ASIATICA ON MITOCHONDRIAL BIOGENESIS IN THE MOUSE BRAIN.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P663, doi. 10.1016/j.jalz.2017.06.794

By:

Matthews, Donald G.;
Gray, Nora E.;
Meshul, Charles;
Caruso, Maya;
Moore, Cynthia;
Murchison, Charles F.;
Harris, Christopher;
Quinn, Joseph F.;
Soumyanath, Amala

Publication type:

Article

A Combined Computational and Experimental Approach to Studying Tropomyosin Kinase Receptor B Binders for Potential Treatment of Neurodegenerative Diseases.

Published in:

Molecules, 2024, v. 29, n. 17, p. 3992, doi. 10.3390/molecules29173992

By:

Nguyen, Duc D.;
Mansur, Shomit;
Ciesla, Lukasz;
Gray, Nora E.;
Zhao, Shan;
Bao, Yuping

Publication type:

Article

Integrating High-Resolution Mass Spectral Data, Bioassays and Computational Models to Annotate Bioactives in Botanical Extracts: Case Study Analysis of C. asiatica Extract Associates Dicaffeoylquinic Acids with Protection against Amyloid-β Toxicity.

Published in:

Molecules, 2024, v. 29, n. 4, p. 838, doi. 10.3390/molecules29040838

By:

Alcázar Magaña, Armando;
Vaswani, Ashish;
Brown, Kevin S.;
Jiang, Yuan;
Alam, Md Nure;
Caruso, Maya;
Lak, Parnian;
Cheong, Paul;
Gray, Nora E.;
Quinn, Joseph F.;
Soumyanath, Amala;
Stevens, Jan F.;
Maier, Claudia S.

Publication type:

Article

NRF2 as a Therapeutic Target in Neurodegenerative Diseases.

Published in:

ASN Neuro, 2020, v. 12, p. N.PAG, doi. 10.1177/1759091419899782

By:

Brandes, Mikah S.;
Gray, Nora E.

Publication type:

Article

NRF2 as a Therapeutic Target in Neurodegenerative Diseases.

Published in:

ASN Neuro, 2020, v. 12, p. 1, doi. 10.1177/1759091419899782

By:

Brandes, Mikah S.;
Gray, Nora E.

Publication type:

Article