Works by Gratchev, Alexei

Results: 40

Assessing the Clinical Relevance of Soluble PD-1 and PD-L1: A Multi-Cohort Study Across Diverse Tumor Types and Prognostic Implications.

Published in:

Biomedicines, 2025, v. 13, n. 2, p. 500, doi. 10.3390/biomedicines13020500

By:

Kushlinskii, Nikolay E.;
Kovaleva, Olga V.;
Gratchev, Alexei N.;
Alferov, Alexander A.;
Kuzmin, Yurii B.;
Sokolov, Nikolai Y.;
Tsekatunov, Dmitry A.;
Ryzhavskaya, Irina B.;
Kuznetsov, Igor N.;
Kushlinskii, Dmitry N.;
Mamedli, Zaman Z.;
Stilidi, Ivan S.

Publication type:

Article

Macrophage Phenotype in Combination with Tumor Microbiome Composition Predicts RCC Patients' Survival: A Pilot Study.

Published in:

Biomedicines, 2022, v. 10, n. 7, p. N.PAG, doi. 10.3390/biomedicines10071516

By:

Kovaleva, Olga V.;
Podlesnaya, Polina;
Sorokin, Maxim;
Mochalnikova, Valeria;
Kataev, Vladimir;
Khlopko, Yuriy A.;
Plotnikov, Andrey O.;
Stilidi, Ivan S.;
Kushlinskii, Nikolay E.;
Gratchev, Alexei

Publication type:

Article

Macrophages in Health and Non-Infectious Disease 2.0.

Published in:

Biomedicines, 2022, v. 10, n. 6, p. 1215, doi. 10.3390/biomedicines10061215

By:

Bezsonov, Evgeny E.;
Gratchev, Alexei;
Orekhov, Alexander N.

Publication type:

Article

Prognostic Significance of the Microbiome and Stromal Cells Phenotype in Esophagus Squamous Cell Carcinoma.

Published in:

Biomedicines, 2021, v. 9, n. 7, p. 743, doi. 10.3390/biomedicines9070743

By:

Kovaleva, Olga;
Podlesnaya, Polina;
Rashidova, Madina;
Samoilova, Daria;
Petrenko, Anatoly;
Mochalnikova, Valeria;
Kataev, Vladimir;
Khlopko, Yuri;
Plotnikov, Andrey;
Gratchev, Alexei

Publication type:

Article

NOD1-Targeted Immunonutrition Approaches: On the Way from Disease to Health.

Published in:

Biomedicines, 2021, v. 9, n. 5, p. 519, doi. 10.3390/biomedicines9050519

By:

Fernández-García, Victoria;
González-Ramos, Silvia;
Martín-Sanz, Paloma;
Laparra, José M.;
Boscá, Lisardo;
Gratchev, Alexei

Publication type:

Article

Phenotypic and Functional Heterogeneity of Low-Density and High-Density Human Lung Macrophages.

Published in:

Biomedicines, 2021, v. 9, n. 5, p. 505, doi. 10.3390/biomedicines9050505

By:

Balestrieri, Barbara;
Granata, Francescopaolo;
Loffredo, Stefania;
Petraroli, Angelica;
Scalia, Giulia;
Morabito, Paolo;
Cardamone, Chiara;
Varricchi, Gilda;
Triggiani, Massimo;
Gratchev, Alexei

Publication type:

Article

The Effects of Macrophage Phenotype on Osteogenic Differentiation of MSCs in the Presence of Polyethylene Particles.

Published in:

Biomedicines, 2021, v. 9, n. 5, p. 499, doi. 10.3390/biomedicines9050499

By:

Gao, Qi;
Rhee, Claire;
Maruyama, Masahiro;
Li, Zhong;
Shen, Huaishuang;
Zhang, Ning;
Utsunomiya, Takeshi;
Huang, Elijah Ejun;
Yao, Zhenyu;
Bunnell, Bruce A.;
Lin, Hang;
Tuan, Rocky S.;
Goodman, Stuart B.;
Gratchev, Alexei

Publication type:

Article

Macrophages in Health and Non-Infectious Disease.

Published in:

2021

By:

Bezsonov, Evgeny E.;
Gratchev, Alexei;
Orekhov, Alexander N.

Publication type:

Editorial

Deciphering the Role of Heme Oxygenase-1 (HO-1) Expressing Macrophages in Renal Ischemia-Reperfusion Injury.

Published in:

Biomedicines, 2021, v. 9, n. 3, p. 306, doi. 10.3390/biomedicines9030306

By:

Rossi, Maxime;
Korpak, Kéziah;
Doerfler, Arnaud;
Zouaoui Boudjeltia, Karim;
Gratchev, Alexei

Publication type:

Article

Fetal Macrophages Exposed to Salmonella Antigens Elicit Protective Immunity Against Overwhelming Salmonella Challenge in A Murine Model.

Published in:

Biomedicines, 2021, v. 9, n. 3, p. 245, doi. 10.3390/biomedicines9030245

By:

Chen, Jeng-Chang;
Ou, Liang-Shiou;
Kuo, Ming-Ling;
Tseng, Li-Yun;
Chang, Hsueh-Ling;
Chen, Shiang-Chi;
Chiu, Cheng-Hsun;
Gratchev, Alexei

Publication type:

Article

Statins Directly Influence the Polarization of Adipose Tissue Macrophages: A Role in Chronic Inflammation.

Published in:

Biomedicines, 2021, v. 9, n. 2, p. 211, doi. 10.3390/biomedicines9020211

By:

Kauerova, Sona;
Bartuskova, Hana;
Muffova, Barbora;
Janousek, Libor;
Fronek, Jiri;
Petras, Marek;
Poledne, Rudolf;
Kralova Lesna, Ivana;
Gratchev, Alexei;
Jeon, Byeong Hwa

Publication type:

Article

Netrin-1 in Atherosclerosis: Relationship between Human Macrophage Intracellular Levels and In Vivo Plaque Morphology.

Published in:

Biomedicines, 2021, v. 9, n. 2, p. 168, doi. 10.3390/biomedicines9020168

By:

Fiorelli, Susanna;
Cosentino, Nicola;
Porro, Benedetta;
Fabbiocchi, Franco;
Niccoli, Giampaolo;
Fracassi, Francesco;
Capra, Nicolò;
Barbieri, Simone;
Crea, Filippo;
Marenzi, Giancarlo;
Cavalca, Viviana;
Tremoli, Elena;
Eligini, Sonia;
Gratchev, Alexei;
Orekhov, Alexander N.

Publication type:

Article

Lung Microbiome Differentially Impacts Survival of Patients with Non-Small Cell Lung Cancer Depending on Tumor Stroma Phenotype.

Published in:

Biomedicines, 2020, v. 8, n. 9, p. 349, doi. 10.3390/biomedicines8090349

By:

Kovaleva, Olga;
Podlesnaya, Polina;
Rashidova, Madina;
Samoilova, Daria;
Petrenko, Anatoly;
Zborovskaya, Irina;
Mochalnikova, Valeria;
Kataev, Vladimir;
Khlopko, Yuri;
Plotnikov, Andrey;
Gratchev, Alexei

Publication type:

Article

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.

Published in:

2011

By:

Schledzewski, Kai;
Géraud, Cyrill;
Arnold, Bernd;
Shijun Wang;
Gröne, Hermann-Josef;
Kempf, Tubor;
Wollert, Kai C.;
Straub, Beate K.;
Schirmacher, Peter;
Demory, Alexandra;
Schönhaber, Hiltrud;
Gratchev, Alexei;
Dietz, Lisa;
Thierse, Hermann-Josef;
Kzhyshkowska, Julia;
Goerdt, Sergij;
Géraud, Cyrill;
Wang, Shijun;
Gröne, Hermann-Josef;
Kempf, Tibor

Publication type:

journal article

Harnessing the Multifunctionality in Nature: A Bioactive Agent Release System with Self-Antimicrobial and Immunomodulatory Properties.

Published in:

Advanced Healthcare Materials, 2015, v. 4, n. 13, p. 2026, doi. 10.1002/adhm.201500546

By:

Özçelik, Hayriye;
Vrana, Nihal Engin;
Gudima, Alexandru;
Riabov, Vladimir;
Gratchev, Alexei;
Haikel, Youssef;
Metz‐Boutigue, Marie‐Hélène;
Carradò, Adele;
Faerber, Jacques;
Roland, Thierry;
Klüter, Harald;
Kzhyshkowska, Julia;
Schaaf, Pierre;
Lavalle, Philippe

Publication type:

Article

Expression of Osteoarthritis Marker YKL-39 is Stimulated by Transforming Growth Factor Beta (TGF-beta) and IL-4 in Differentiating Macrophages.

Published in:

Biomarker Insights, 2008, n. 3, p. 39, doi. 10.1177/117727190800300003

By:

Gratchev, Alexei;
Schmuttermaier, Christina;
Mamidi, Srinivas;
LiMing Gooi;
Goerdt, Sergij;
Kzhyshkowska, Julia

Publication type:

Article

Characterization of Three XPG-Defective Patients Identifies Three Missense Mutations that Impair Repair and Transcription.

Published in:

Journal of Investigative Dermatology, 2013, v. 133, n. 7, p. 1841, doi. 10.1038/jid.2013.54

By:

Schäfer, Annika;
Schubert, Steffen;
Gratchev, Alexei;
Seebode, Christina;
Apel, Antje;
Laspe, Petra;
Hofmann, Lars;
Ohlenbusch, Andreas;
Mori, Toshio;
Kobayashi, Nobuhiko;
Schürer, Anke;
Schön, Michael P;
Emmert, Steffen

Publication type:

Article

CHID1 Is a Novel Prognostic Marker of Non-Small Cell Lung Cancer.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 450, doi. 10.3390/ijms22010450

By:

Kovaleva, Olga V.;
Rashidova, Madina A.;
Samoilova, Daria V.;
Podlesnaya, Polina A.;
Tabiev, Rasul M.;
Mochalnikova, Valeria V.;
Gratchev, Alexei

Publication type:

Article

Role of Phagocytosis in the Pro-Inflammatory Response in LDL-Induced Foam Cell Formation; a Transcriptome Analysis.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 3, p. 817, doi. 10.3390/ijms21030817

By:

Orekhov, Alexander N.;
Nikiforov, Nikita G.;
Sukhorukov, Vasily N.;
Kubekina, Marina V.;
Sobenin, Igor A.;
Wu, Wei-Kai;
Foxx, Kathy K.;
Pintus, Sergey;
Stegmaier, Philip;
Stelmashenko, Daria;
Kel, Alexander;
Gratchev, Alexei N.;
Melnichenko, Alexandra A.;
Wetzker, Reinhard;
Summerhill, Volha I.;
Manabe, Ichiro;
Oishi, Yumiko

Publication type:

Article

Perspectives for Monocyte/Macrophage-Based Diagnostics of Chronic Inflammation.

Published in:

Transfusion Medicine & Hemotherapy, 2016, v. 43, n. 2, p. 66, doi. 10.1159/000444943

By:

Kzhyshkowska, Julia;
Gudima, alexandru;
Moganti, Kondaiah;
Gratchev, alexei;
Orekhov, alexander

Publication type:

Article

Human Lung Microbiome on the Way to Cancer.

Published in:

2019

By:

Kovaleva, Olga V.;
Romashin, Daniil;
Zborovskaya, Irina B.;
Davydov, Mikhail M.;
Shogenov, Murat S.;
Gratchev, Alexei

Publication type:

journal article

The expression of metastasis suppressor MIM/MTSS1 is regulated by DNA methylation.

Published in:

International Journal of Cancer, 2006, v. 119, n. 10, p. 2287, doi. 10.1002/ijc.22106

By:

Utikal, Jochen;
Gratchev, Alexei;
Muller-Molinet, Isabelle;
Oerther, Sandra;
Kzhyshkowska, Julia;
Arens, Norbert;
Grobholz, Rainer;
Kannookadan, Sheila;
Goerdt, Sergij

Publication type:

Article

Differential gene expression in colon carcinoma cells and tissues detected with a cDNA array.

Published in:

International Journal of Cancer, 1999, v. 82, n. 6, p. 868, doi. 10.1002/(SICI)1097-0215(19990909)82:6<868::AID-IJC16>3.0.CO;2-W

By:

Backert, Steffen;
Gelos, Marcos;
Kobalz, Ursula;
Hanski, Marie-Luise;
Böhm, Christian;
Mann, Benno;
Lövin, Nicole;
Gratchev, Alexei;
Mansmann, Ulrich;
Moyer, Mary Pat;
Riecken, Ernst-Otto;
Hanski, Christoph

Publication type:

Article

Macrophages of Human First Trimester Decidua Express Markers Associated to Alternative Activation.

Published in:

American Journal of Reproductive Immunology, 2004, v. 51, n. 2, p. 117, doi. 10.1046/j.8755-8920.2003.00128.x

By:

Cupurdija, Kristijan;
Azzola, Dagmar;
Hainz, Ursula;
Gratchev, Alexei;
Heitger, Andreas;
Takikawa, Osamu;
Goerdt, Sergij;
Wintersteiger, Reinhold;
Dohr, Gottfried;
Sedlmayr, Peter

Publication type:

Article

Xeroderma Pigmentosum-Variant Patients from America, Europe, and Asia.

Published in:

Journal of Investigative Dermatology, 2008, v. 128, n. 8, p. 2055, doi. 10.1038/jid.2008.48

By:

Inui, Hiroki;
Oh, Kyu-Seon;
Nadem, Carine;
Ueda, Takahiro;
Khan, Sikandar G.;
Metin, Ahmet;
Gozukara, Engin;
Emmert, Steffen;
Slor, Hanoch;
Busch, David B.;
Baker, Carl C.;
DiGiovanna, John J.;
Tamura, Deborah;
Seitz, Cornelia S.;
Gratchev, Alexei;
Wu, Wen Hao;
Chung, Kee Yang;
Chung, Hye Jin;
Azizi, Esther;
Woodgate, Roger

Publication type:

Article

Functional Characterization of the Epidermal Cholinergic System In Vitro.

Published in:

Journal of Investigative Dermatology, 2006, v. 126, n. 11, p. 2458, doi. 10.1038/sj.jid.5700443

By:

Kurzen, Hjalmar;
Henrich, Carmen;
Booken, Dirk;
Poenitz, Nina;
Gratchev, Alexei;
Klemke, Claus-Detlev;
Engstner, Monika;
Goerdt, Sergij;
Maas-Szabowski, Nicole

Publication type:

Article

Phenotypical and Molecular Profiling of the Extraneuronal Cholinergic System of the Skin.

Published in:

Journal of Investigative Dermatology, 2004, v. 123, n. 5, p. 937, doi. 10.1111/j.0022-202X.2004.23425.x

By:

Kurzen, Hjalmar;
Berger, Hans;
Jäger, Claudia;
Hartschuh, Wolfgang;
Näher, Helmut;
Gratchev, Alexei;
Goerdt, Sergij;
Deichmann, Martin

Publication type:

Article

A TNF-Regulated Recombinatorial Macrophage Immune Receptor Implicated in Granuloma Formation in Tuberculosis.

Published in:

PLoS Pathogens, 2011, v. 7, n. 11, p. 1, doi. 10.1371/journal.ppat.1002375

By:

Beham, Alexander W.;
Puellmann, Kerstin;
Laird, Rebecca;
Fuchs, Tina;
Streich, Roswita;
Breysach, Caroline;
Raddatz, Dirk;
Oniga, Septimia;
Peccerella, Teresa;
Findeisen, Peter;
Kzhyshkowska, Julia;
Gratchev, Alexei;
Schweyer, Stefan;
Saunders, Bernadette;
Wessels, Johannes T.;
Möbius, Wiebke;
Keane, Joseph;
Becker, Heinz;
Ganser, Arnold;
Neumaier, Michael

Publication type:

Article

A Novel GGA-Binding Site Is Required for Intracellular Sorting Mediated by Stabilin-1.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 22, p. 11, doi. 10.1128/MCB.00505-09

By:

Jingjing Zhang;
Gratchev, Alexei;
Riabov, Vladimir;
Mamidi, Srinivas;
Schmuttermaier, Christina;
Krusell, Liis;
Kremmer, Elisabeth;
Workman, Gail;
Sage, E. Helene;
Jalkanen, Sirpa;
Goerdt, Sergij;
Kzhyshkowska, Julia

Publication type:

Article

SI‐CLP inhibits the growth of mouse mammary adenocarcinoma by preventing recruitment of tumor‐associated macrophages.

Published in:

International Journal of Cancer, 2020, v. 146, n. 5, p. 1396, doi. 10.1002/ijc.32685

By:

Yin, Shuiping;
Wang, Nan;
Riabov, Vladimir;
Mossel, Dieuwertje M.;
Larionova, Irina;
Schledzewski, Kai;
Trofimova, Olga;
Sevastyanova, Tatyana;
Zajakina, Anna;
Schmuttermaier, Christina;
Gratchev, Alexei;
Flatley, Andrew;
Kremmer, Elisabeth;
Zavyalova, Marina;
Cherdyntseva, Nadezhda;
Simon‐Keller, Katja;
Marx, Alexander;
Klüter, Harald;
Goerdt, Sergij;
Kzhyshkowska, Julia

Publication type:

Article

Die kutanen Non-Langerhans-Zell-Histiozytosen.

Published in:

Journal der Deutschen Dermatologischen Gesellschaft, 2003, v. 1, n. 6, p. 471, doi. 10.1046/j.1610-0387.2003.03551.x

By:

Erstautoren*, Jochen Utikalgleichberechtigte;
Klemke*, Claus-Detlev;
Gratchev, Alexei;
Goerdt, Sergij

Publication type:

Article

Novel adapter protein AP162 connects a sialyl-Le<sup>x</sup>-positive mucin with an apoptotic signal transduction pathway.

Published in:

Glycoconjugate Journal, 2001, v. 18, n. 11/12, p. 915, doi. 10.1023/A:1022256610674

By:

Hartel-Schenk, Sabine;
Gratchev, Alexei;
Hanski, Marie-Luise;
Ogorek, Dieter;
Trendelenburg, George;
Hummel, Michael;
Höpfner, Michael;
Scherübl, Hans;
Zeitz, Martin;
Hanski, Christoph

Publication type:

Article

A unique chromosomal in-frame deletion identified among seven XP-C patients.

Published in:

Photodermatology, Photoimmunology & Photomedicine, 2016, v. 32, n. 5/6, p. 276, doi. 10.1111/phpp.12251

By:

Schubert, Steffen;
Rieper, Petra;
Ohlenbusch, Andreas;
Seebode, Christina;
Lehmann, Janin;
Gratchev, Alexei;
Emmert, Steffen

Publication type:

Article

Functional and molecular genetic analyses of nine newly identified XPD-deficient patients reveal a novel mutation resulting in TTD as well as in XP/ CS complex phenotypes.

Published in:

Experimental Dermatology, 2013, v. 22, n. 7, p. 486, doi. 10.1111/exd.12166

By:

Schäfer, Annika;
Gratchev, Alexei;
Seebode, Christina;
Hofmann, Lars;
Schubert, Steffen;
Laspe, Petra;
Apel, Antje;
Ohlenbusch, Andreas;
Tzvetkov, Mladen;
Weishaupt, Carsten;
Oji, Vinzenz;
Schön, Michael P.;
Emmert, Steffen

Publication type:

Article

Molecular genetic analysis of 16 XP- C patients from Germany: environmental factors predominately contribute to phenotype variations.

Published in:

Experimental Dermatology, 2013, v. 22, n. 1, p. 24, doi. 10.1111/exd.12052

By:

Schäfer, Annika;
Hofmann, Lars;
Gratchev, Alexei;
Laspe, Petra;
Schubert, Steffen;
Schürer, Anke;
Ohlenbusch, Andreas;
Tzvetkov, Mladen;
Hallermann, Christian;
Reichrath, Jörg;
Schön, Michael P.;
Emmert, Steffen

Publication type:

Article

Molecular genetics of Xeroderma pigmentosum variant.

Published in:

Experimental Dermatology, 2003, v. 12, n. 5, p. 529, doi. 10.1034/j.1600-0625.2003.00124.x

By:

Gratchev, Alexei;
Strein, Pamela;
Utikal, Jochen;
Goerdt, Sergij

Publication type:

Article

Immunosuppressive Phenotype of Esophagus Tumors Stroma.

Published in:

Analytical Cellular Pathology: Cellular Oncology, 2020, p. 1, doi. 10.1155/2020/5424780

By:

Kovaleva, Olga V.;
Rashidova, Madina A.;
Samoilova, Daria V.;
Podlesnaya, Polina A.;
Mochalnikova, Valeria V.;
Gratchev, Alexei

Publication type:

Article

Tumor Associated Macrophages in Kidney Cancer.

Published in:

Analytical Cellular Pathology: Cellular Oncology, 2016, p. 1, doi. 10.1155/2016/9307549

By:

Kovaleva, Olga V.;
Samoilova, Daria V.;
Shitova, Maria S.;
Gratchev, Alexei

Publication type:

Article

Cutaneous leiomyosarcoma with myxoid alteration arising in a setting of multiple cutaneous smooth muscle neoplasms.

Published in:

Journal of Cutaneous Pathology, 2006, v. 33, p. 20, doi. 10.1111/j.1600-0560.2006.00491.x

By:

Utikal, Jochen;
Haus, Georg;
Poenitz, Nina;
Koenen, Wolfgang;
Back, Walter;
Dippel, Edgar;
Gratchev, Alexei;
Goerdt, Sergij

Publication type:

Article

Resident Microbiome of Kidney Tumors.

Published in:

Oncology Reviews, 2024, p. 1, doi. 10.3389/or.2024.1393664

By:

Kovaleva, Olga;
Podlesnaya, Polina;
Gratchev, Alexei

Publication type:

Article