Works by Grassmé, Heike

Results: 27

Acid sphingomyelinase-ceramide system mediates effects of antidepressant drugs.

Published in:

Nature Medicine, 2013, v. 19, n. 7, p. 934, doi. 10.1038/nm.3214

By:

Gulbins, Erich;
Palmada, Monica;
Reichel, Martin;
Lüth, Anja;
Böhmer, Christoph;
Amato, Davide;
Müller, Christian P;
Tischbirek, Carsten H;
Groemer, Teja W;
Tabatabai, Ghazaleh;
Becker, Katrin A;
Tripal, Philipp;
Staedtler, Sven;
Ackermann, Teresa F;
van Brederode, Johannes;
Alzheimer, Christian;
Weller, Michael;
Lang, Undine E;
Kleuser, Burkhard;
Grassmé, Heike

Publication type:

Article

Neutral Sphingomyelinase in Physiological and Measles Virus Induced T Cell Suppression.

Published in:

PLoS Pathogens, 2014, v. 10, n. 12, p. 1, doi. 10.1371/journal.ppat.1004574

By:

Mueller, Nora;
Avota, Elita;
Collenburg, Lena;
Grassmé, Heike;
Schneider-Schaulies, Sibylle

Publication type:

Article

Regulation of Neuronal Stem Cell Proliferation in the Hippocampus by Endothelial Ceramide.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2016, v. 39, n. 2, p. 790, doi. 10.1159/000447789

By:

Gulbins, anne;
Grassmé, Heike;
Hoehn, Richard;
Wilker, Barbara;
Soddemann, Matthias;
Kohnen, Marcus;
Edwards, Michael J.;
Kornhuber, Johannes;
Gulbins, Erich

Publication type:

Article

Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fibrosis.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2016, v. 38, n. 6, p. 2094, doi. 10.1159/000445567

By:

Tavakoli Tabazavareh, Shaghayegh;
Seitz, aaron;
Jernigan, Peter;
Sehl, Carolin;
Keitsch, Simone;
Lang, Stephan;
Kahl, Barbara C.;
Edwards, Michael;
Grassmé, Heike;
Gulbins, Erich;
Becker, Katrin anne

Publication type:

Article

Regulation of the Inflammasome by Ceramide in Cystic Fibrosis Lungs.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2014, v. 34, n. 1, p. 45, doi. 10.1159/000362983

By:

Grassmé, Heike;
Carpinteiro, alexander;
Edwards, Michael J.;
Gulbins, Erich;
Becker, Katrin anne

Publication type:

Article

Ceramide in Pseudomonas aeruginosa Infections and Cystic Fibrosis.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2010, v. 26, n. 1, p. 57, doi. 10.1159/000315106

By:

Becker, Katrin Anne;
Grassmé, Heike;
Yang Zhang;
Gulbins, Erich

Publication type:

Article

DNA Quantification and Fragmentation in Sputum after Inhalation of Recombinant Human Deoxyribonuclease.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2008, v. 22, n. 1-4, p. 347, doi. 10.1159/000149813

By:

Riethmueller, Joachim;
Vonthein, Reinhard;
Borth-Bruhns, Thomas;
Grassmé, Heike;
Eyrich, Matthias;
Schilbach, Karin;
Stern, Martin;
Gulbins, Erich

Publication type:

Article

Acid Sphingomyelinase-Ceramide System in Bacterial Infections.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2019, v. 52, n. 2, p. 280, doi. 10.33594/000000021

By:

Cao Li;
Anni Wang;
Yuqing Wu;
Gulbins, Erich;
Grassmé, Heike;
Zhigang Zhao

Publication type:

Article

Ceramide, membrane rafts and infections.

Published in:

Journal of Molecular Medicine, 2004, v. 82, n. 6, p. 357, doi. 10.1007/s00109-004-0539-y

By:

Gulbins, Erich;
Dreschers, Stephan;
Wilker, Barbara;
Grassmé, Heike

Publication type:

Article

Regulation of hematogenous tumor metastasis by acid sphingomyelinase.

Published in:

EMBO Molecular Medicine, 2015, v. 7, n. 6, p. 714, doi. 10.15252/emmm.201404571

By:

Carpinteiro, Alexander;
Becker, Katrin Anne;
Japtok, Lukasz;
Hessler, Gabriele;
Keitsch, Simone;
Požgajovà, Miroslava;
Schmid, Kurt W;
Adams, Constantin;
Müller, Stefan;
Kleuser, Burkhard;
Edwards, Michael J;
Grassmé, Heike;
Helfrich, Iris;
Gulbins, Erich

Publication type:

Article

Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa.

Published in:

EMBO Molecular Medicine, 2014, v. 6, n. 9, p. 1205, doi. 10.15252/emmm.201404075

By:

Pewzner‐Jung, Yael;
Tavakoli Tabazavareh, Shaghayegh;
Grassmé, Heike;
Becker, Katrin Anne;
Japtok, Lukasz;
Steinmann, Jörg;
Joseph, Tammar;
Lang, Stephan;
Tuemmler, Burkhard;
Schuchman, Edward H;
Lentsch, Alex B;
Kleuser, Burkhard;
Edwards, Michael J;
Futerman, Anthony H;
Gulbins, Erich

Publication type:

Article

Role of Janus-Kinases in Major Depressive Disorder.

Published in:

NeuroSignals (Karger AG), 2016, v. 24, n. 1, p. 71, doi. 10.1159/000442613

By:

Gulbins, anne;
Grassmé, Heike;
Hoehn, Richard;
Kohnen, Marcus;
Edwards, Michael J.;
Kornhuber, Johannes;
Gulbins, Erich

Publication type:

Article

Melatonin Acts as an Antidepressant by Inhibition of the Acid Sphingomyelinase/Ceramide System.

Published in:

NeuroSignals (Karger AG), 2016, v. 24, n. 1, p. 48, doi. 10.1159/000442611

By:

Hoehn, Richard;
Monse, Marlene;
Pohl, Ella;
Wranik, Sina;
Wilker, Barbara;
Keitsch, Simone;
Soddemann, Matthias;
Kornhuber, Johannes;
Kohnen, Marcus;
Edwards, Michael J.;
Grassmé, Heike;
Gulbins, Erich

Publication type:

Article

Sphingolipids in Major Depression.

Published in:

NeuroSignals (Karger AG), 2015, v. 23, n. 1, p. 49, doi. 10.1159/000442603

By:

Jernigan, Peter L.;
Hoehn, Richard S.;
Grassmé, Heike;
Edwards, Michael J.;
Müller, Christian P;
Kornhuber, Johannes;
Gulbins, Erich

Publication type:

Article

Inhibition of Acid Sphingomyelinase by Antidepressants Counteracts Stress-Induced Activation of P38-Kinase in Major Depression.

Published in:

NeuroSignals (Karger AG), 2015, v. 23, n. 1, p. 84, doi. 10.1159/000442606

By:

Grassmé, Heike;
Jernigan, Peter L.;
Hoehn, Richard S.;
Wilker, Barbara;
Soddemann, Matthias;
Edwards, Michael J.;
Müller, Christian P.;
Kornhuber, Johannes;
Gulbins, Erich

Publication type:

Article

Ceramide-mediated clustering is required for CD95-DISC formation.

Published in:

Oncogene, 2003, v. 22, n. 35, p. 5457, doi. 10.1038/sj.onc.1206540

By:

Grassmé, Heike;
Cremesti, Aida;
Kolesnick, Richard;
Gulbins, Erich

Publication type:

Article

Fas/CD95/Apo-I activates the acidic sphingomyelinase via Caspases.

Published in:

Cell Death & Differentiation, 1998, v. 5, n. 1, p. 29, doi. 10.1038/sj.cdd.4400307

By:

Brenner, Brigit;
Ferlinz, Klaus;
Grassmé, Heike;
Weller, Michael;
Koppenhoefer, Ursula;
Dichgans, Johannes;
Sandhoff, Konrad;
Lang, Florian;
Gulbins, Erich

Publication type:

Article

The Anti-Infectious Role of Sphingosine in Microbial Diseases.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1105, doi. 10.3390/cells10051105

By:

Wu, Yuqing;
Liu, Yongjie;
Gulbins, Erich;
Grassmé, Heike;
Scholich, Klaus

Publication type:

Article

Acid Sphingomyelinase Contributes to the Control of Mycobacterial Infection via a Signaling Cascade Leading from Reactive Oxygen Species to Cathepsin D.

Published in:

Cells (2073-4409), 2020, v. 9, n. 11, p. 2406, doi. 10.3390/cells9112406

By:

Wu, Yuqing;
Li, Cao;
Peng, Huiming;
Swaidan, Ashraf;
Riehle, Andrea;
Pollmeier, Barbara;
Zhang, Yang;
Gulbins, Erich;
Grassmé, Heike

Publication type:

Article

Reduced Sphingosine in Cystic Fibrosis Increases Susceptibility to Mycobacterium abscessus Infections.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 14004, doi. 10.3390/ijms241814004

By:

Schnitker, Fabian;
Liu, Yongjie;
Keitsch, Simone;
Soddemann, Matthias;
Verhasselt, Hedda Luise;
Kehrmann, Jan;
Grassmé, Heike;
Kamler, Markus;
Gulbins, Erich;
Wu, Yuqing

Publication type:

Article

Mycobacterial Infection is Promoted by Neutral Sphingomyelinase 2 Regulating a Signaling Cascade Leading to Activation of β1-Integrin.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2018, v. 51, n. 4, p. 1815, doi. 10.1159/000495683

By:

Wu, Yuqing;
Li, Cao;
Riehle, Andrea;
Pollmeier, Barbara;
Gulbins, Erich;
Grassmé, Heike

Publication type:

Article

Sphingosine kills Mycobacteria and suppresses mycobacterial lung infections.

Published in:

Journal of Molecular Medicine, 2025, v. 103, n. 5, p. 547, doi. 10.1007/s00109-025-02534-z

By:

Wu, Yuqing;
Schnitker, Fabian;
Liu, Yongjie;
Keitsch, Simone;
Caicci, Federico;
Schumacher, Fabian;
Riehle, Andrea;
Pollmeier, Barbara;
Kehrmann, Jan;
Kleuser, Burkhard;
Kamler, Markus;
Szabo, Ildiko;
Grassmé, Heike;
Gulbins, Erich

Publication type:

Article

Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis.

Published in:

Journal of Molecular Medicine, 2015, v. 93, n. 6, p. 675, doi. 10.1007/s00109-014-1246-y

By:

Peng, Huiming;
Li, Cao;
Kadow, Stephanie;
Henry, Brian;
Steinmann, Jörg;
Becker, Katrin;
Riehle, Andrea;
Beckmann, Natalie;
Wilker, Barbara;
Li, Pin-Lan;
Pritts, Timothy;
Edwards, Michael;
Zhang, Yang;
Gulbins, Erich;
Grassmé, Heike

Publication type:

Article

Role of CD95 in pulmonary inflammation and infection in cystic fibrosis.

Published in:

Journal of Molecular Medicine, 2012, v. 90, n. 9, p. 1011, doi. 10.1007/s00109-012-0867-2

By:

Becker, Katrin;
Henry, Brian;
Ziobro, Regan;
Tümmler, Burkhard;
Gulbins, Erich;
Grassmé, Heike

Publication type:

Article

Ceramide in bacterial infections and cystic fibrosis.

Published in:

Biological Chemistry, 2008, v. 389, n. 11, p. 1371, doi. 10.1515/BC.2008.162

By:

Grassmé, Heike;
Becker, Katrin Anne;
Zhang, Yang;
Gulbins, Erich

Publication type:

Article

The function of sphingomyelinases in mycobacterial infections.

Published in:

Biological Chemistry, 2018, v. 399, n. 10, p. 1125, doi. 10.1515/hsz-2018-0179

By:

Yuqing Wu;
Gulbins, Erich;
Grassmé, Heike

Publication type:

Article

Ceramide and sphingosine in pulmonary infections.

Published in:

Biological Chemistry, 2015, v. 396, n. 6/7, p. 611, doi. 10.1515/hsz-2014-0285

By:

Seitz, Aaron P.;
Grassmé, Heike;
Edwards, Michael J.;
Pewzner-Jung, Yael;
Gulbins, Erich

Publication type:

Article