Works by Granier, Sebastien

Results: 21

Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases**.

Published in:

Angewandte Chemie, 2022, v. 134, n. 2, p. 1, doi. 10.1002/ange.202109967

By:

Healey, Robert D.;
Saied, Essa M.;
Cong, Xiaojing;
Karsai, Gergely;
Gabellier, Ludovic;
Saint‐Paul, Julie;
Del Nero, Elise;
Jeannot, Sylvain;
Drapeau, Marion;
Fontanel, Simon;
Maurel, Damien;
Basu, Shibom;
Leyrat, Cedric;
Golebiowski, Jérôme;
Bossis, Guillaume;
Bechara, Cherine;
Hornemann, Thorsten;
Arenz, Christoph;
Granier, Sebastien

Publication type:

Article

Innenrücktitelbild: Selective and Wash‐Resistant Fluorescent Dihydrocodeinone Derivatives Allow Single‐Molecule Imaging of μ‐Opioid Receptor Dimerization (Angew. Chem. 15/2020).

Published in:

Angewandte Chemie, 2020, v. 132, n. 15, p. 6348, doi. 10.1002/ange.202002281

By:

Gentzsch, Christian;
Seier, Kerstin;
Drakopoulos, Antonios;
Jobin, Marie‐Lise;
Lanoiselée, Yann;
Koszegi, Zsombor;
Maurel, Damien;
Sounier, Rémy;
Hübner, Harald;
Gmeiner, Peter;
Granier, Sébastien;
Calebiro, Davide;
Decker, Michael

Publication type:

Article

Selective and Wash‐Resistant Fluorescent Dihydrocodeinone Derivatives Allow Single‐Molecule Imaging of μ‐Opioid Receptor Dimerization.

Published in:

Angewandte Chemie, 2020, v. 132, n. 15, p. 6014, doi. 10.1002/ange.201912683

By:

Gentzsch, Christian;
Seier, Kerstin;
Drakopoulos, Antonios;
Jobin, Marie‐Lise;
Lanoiselée, Yann;
Koszegi, Zsombor;
Maurel, Damien;
Sounier, Rémy;
Hübner, Harald;
Gmeiner, Peter;
Granier, Sébastien;
Calebiro, Davide;
Decker, Michael

Publication type:

Article

Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases**.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 2, p. 1, doi. 10.1002/anie.202109967

By:

Healey, Robert D.;
Saied, Essa M.;
Cong, Xiaojing;
Karsai, Gergely;
Gabellier, Ludovic;
Saint‐Paul, Julie;
Del Nero, Elise;
Jeannot, Sylvain;
Drapeau, Marion;
Fontanel, Simon;
Maurel, Damien;
Basu, Shibom;
Leyrat, Cedric;
Golebiowski, Jérôme;
Bossis, Guillaume;
Bechara, Cherine;
Hornemann, Thorsten;
Arenz, Christoph;
Granier, Sebastien

Publication type:

Article

Inside Back Cover: Selective and Wash‐Resistant Fluorescent Dihydrocodeinone Derivatives Allow Single‐Molecule Imaging of μ‐Opioid Receptor Dimerization (Angew. Chem. Int. Ed. 15/2020).

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 15, p. 6289, doi. 10.1002/anie.202002281

By:

Gentzsch, Christian;
Seier, Kerstin;
Drakopoulos, Antonios;
Jobin, Marie‐Lise;
Lanoiselée, Yann;
Koszegi, Zsombor;
Maurel, Damien;
Sounier, Rémy;
Hübner, Harald;
Gmeiner, Peter;
Granier, Sébastien;
Calebiro, Davide;
Decker, Michael

Publication type:

Article

Selective and Wash‐Resistant Fluorescent Dihydrocodeinone Derivatives Allow Single‐Molecule Imaging of μ‐Opioid Receptor Dimerization.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 15, p. 5958, doi. 10.1002/anie.201912683

By:

Gentzsch, Christian;
Seier, Kerstin;
Drakopoulos, Antonios;
Jobin, Marie‐Lise;
Lanoiselée, Yann;
Koszegi, Zsombor;
Maurel, Damien;
Sounier, Rémy;
Hübner, Harald;
Gmeiner, Peter;
Granier, Sébastien;
Calebiro, Davide;
Decker, Michael

Publication type:

Article

Structure, dynamics and transferability of the metal-dependent polyhistidine tetramerization motif TetrHis for single-chain Fv antibodies.

Published in:

Communications Chemistry, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42004-023-00962-x

By:

Healey, Robert D.;
Couillaud, Louise;
Hoh, François;
Mouhand, Assia;
Fouillen, Aurelien;
Couvineau, Pierre;
Granier, Sébastien;
Leyrat, Cédric

Publication type:

Article

Amphipols in G Protein-Coupled Receptor Pharmacology: What Are They Good For?

Published in:

Journal of Membrane Biology, 2014, v. 247, n. 9/10, p. 853, doi. 10.1007/s00232-014-9665-9

By:

Mary, Sophie;
Damian, Marjorie;
Rahmeh, Rita;
Mouillac, Bernard;
Marie, Jacky;
Granier, Sébastien;
Banères, Jean-Louis

Publication type:

Article

Structure des récepteurs mu et delta des opiacés.

Published in:

Médecine Sciences, 2012, v. 28, n. 10, p. 870, doi. 10.1051/medsci/20122810016

By:

Granier, Sébastien

Publication type:

Article

Signaling from β<sub>1</sub>- and β<sub>2</sub>-adrenergic receptors is defined by differential interactions with PDE4.

Published in:

EMBO Journal, 2008, v. 27, n. 2, p. 384, doi. 10.1038/sj.emboj.7601968

By:

Richter, Wito;
Day, Peter;
Agrawal, Rani;
Bruss, Matthew D;
Granier, Sébastien;
Wang, Yvonne L.;
Rasmussen, Søren G. F.;
Horner, Kathleen;
Ping Wang;
Tao Lei;
Patterson, Andrew J.;
Kobilka, Brian;
Conti, Marco

Publication type:

Article

Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.72555

By:

Lambey, Paul;
Otun, Omolade;
Xiaojing Cong;
Hoh, François;
Brunel, Luc;
Verdié, Pascal;
Grison, Claire M.;
Peysson, Fanny;
Jeannot, Sylvain;
Durroux, Thierry;
Bechara, Cherine;
Granier, Sébastien;
Leyrat, Cédric

Publication type:

Article

Discovery of GPCR ligands for probing signal transduction pathways.

Published in:

Frontiers in Pharmacology, 2014, v. 5, p. 1, doi. 10.3389/fphar.2014.00255

By:

Brogi, Simone;
Tafi, Andrea;
Désaubry, Laurent;
Nebigil, Canan G.;
Pilc, Andrzej;
Granier, Sebastien;
Schmidhammer, Helmut

Publication type:

Article

Structure of the ?-opioid receptor bound to naltrindole.

Published in:

Nature, 2012, v. 485, n. 7398, p. 400, doi. 10.1038/nature11111

By:

Granier, Sébastien;
Manglik, Aashish;
Kruse, Andrew C.;
Kobilka, Tong Sun;
Thian, Foon Sun;
Weis, William I.;
Kobilka, Brian K.

Publication type:

Article

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist.

Published in:

Nature, 2012, v. 485, n. 7398, p. 321, doi. 10.1038/nature10954

By:

Manglik, Aashish;
Kruse, Andrew C.;
Kobilka, Tong Sun;
Thian, Foon Sun;
Mathiesen, Jesper M.;
Sunahara, Roger K.;
Pardo, Leonardo;
Weis, William I.;
Kobilka, Brian K.;
Granier, Sébastien

Publication type:

Article

Bringing GPCR Structural Biology to Medical Applications: Insights from Both V2 Vasopressin and Mu-Opioid Receptors.

Published in:

Membranes, 2023, v. 13, n. 6, p. 606, doi. 10.3390/membranes13060606

By:

Fouillen, Aurélien;
Bous, Julien;
Granier, Sébastien;
Mouillac, Bernard;
Sounier, Remy

Publication type:

Article

A new era of GPCR structural and chemical biology.

Published in:

Nature Chemical Biology, 2012, v. 8, n. 8, p. 670, doi. 10.1038/nchembio.1025

By:

Granier, Sébastien;
Kobilka, Brian

Publication type:

Article

Propagation of conformational changes during μ-opioid receptor activation.

Published in:

Nature, 2015, v. 524, n. 7565, p. 375, doi. 10.1038/nature14680

By:

Sounier, Rémy;
Mas, Camille;
Steyaert, Jan;
Laeremans, Toon;
Manglik, Aashish;
Huang, Weijiao;
Kobilka, Brian K.;
Déméné, Héléne;
Granier, Sébastien

Publication type:

Article

Structural insights into µ-opioid receptor activation.

Published in:

Nature, 2015, v. 524, n. 7565, p. 315, doi. 10.1038/nature14886

By:

Huang, Weijiao;
Manglik, Aashish;
Venkatakrishnan, A. J.;
Laeremans, Toon;
Feinberg, Evan N.;
Sanborn, Adrian L.;
Kato, Hideaki E.;
Livingston, Kathryn E.;
Thorsen, Thor S.;
Kling, Ralf C.;
Granier, Sébastien;
Gmeiner, Peter;
Husbands, Stephen M.;
Traynor, John R.;
Weis, William I.;
Steyaert, Jan;
Dror, Ron O.;
Kobilka, Brian K.

Publication type:

Article

Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design.

Published in:

Scientific Reports, 2016, p. 30797, doi. 10.1038/srep30797

By:

Broad, John;
Maurel, Damien;
Kung, Victor W. S.;
Hicks, Gareth A.;
Schemann, Michael;
Barnes, Michael R.;
Kenakin, Terrence P.;
Granier, Sébastien;
Sanger, Gareth J.

Publication type:

Article

Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07864-w

By:

Vasiliauskaité-Brooks, Ieva;
Healey, Robert D.;
Rochaix, Pascal;
Saint-Paul, Julie;
Sounier, Rémy;
Grison, Claire;
Waltrich-Augusto, Thierry;
Fortier, Mathieu;
Hoh, François;
Saied, Essa M.;
Arenz, Christoph;
Basu, Shibom;
Leyrat, Cédric;
Granier, Sébastien

Publication type:

Article

H, C and N backbone chemical shift assignments of camelid single-domain antibodies against active state µ-opioid receptor.

Published in:

Biomolecular NMR Assignments, 2017, v. 11, n. 1, p. 117, doi. 10.1007/s12104-017-9733-z

By:

Sounier, Remy;
Yang, Yinshan;
Hagelberger, Joanna;
Granier, Sébastien;
Déméné, Hélène

Publication type:

Article