Works matching AU Graeber, Simon Y.

Results: 37

Intestinal current measurement detects age-dependent differences in CFTR function in rectal epithelium.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1537095

By:

Graeber, Simon Y.;
Sommerburg, Olaf;
Yu, Yin;
Berges, Julian;
Hirtz, Stephanie;
Scheuermann, Heike;
Berger, Jasmin;
Duerr, Julia;
Mall, Marcus A.

Publication type:

Article

Hypertonic Saline Is Effective in the Prevention and Treatment of Mucus Obstruction, but Not Airway Inflammation, in Mice with Chronic Obstructive Lung Disease.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2013, v. 49, n. 3, p. 410, doi. 10.1165/rcmb.2013-0050OC

By:

Graeber, Simon Y.;
Zhe Zhou-Suckow;
Schatterny, Jolanthe;
Hirtz, Stephanie;
Boucher, Richard C.;
Mall, Marcus A.

Publication type:

Article

A Volatile and Dynamic Longitudinal Microbiome Is Associated With Less Reduction in Lung Function in Adolescents With Cystic Fibrosis.

Published in:

Frontiers in Cellular & Infection Microbiology, 2021, v. 11, p. 1, doi. 10.3389/fcimb.2021.763121

By:

Metzger, Marisa I.;
Graeber, Simon Y.;
Stahl, Mirjam;
Sommerburg, Olaf;
Mall, Marcus A.;
Dalpke, Alexander H.;
Boutin, Sébastien

Publication type:

Article

An optimized protocol for assessment of sputum macrorheology in health and muco-obstructive lung disease.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.912049

By:

Völler, Mirjam;
Addante, Annalisa;
Rulff, Hanna;
von Lospichl, Benjamin;
Gräber, Simon Y.;
Duerr, Julia;
Lauster, Daniel;
Haag, Rainer;
Gradzielski, Michael;
Mall, Marcus A.

Publication type:

Article

Depression Symptoms in Patients with Cystic Fibrosis Fluctuate at Baseline and Improve with Elexacaftor/Tezacaftor/Ivacaftor Therapy.

Published in:

2024

By:

Piehler, Linus;
Thalemann, Ralf;
Lehmann, Christine;
Stahl, Mirjam;
Mall, Marcus A.;
Graeber, Simon Y.

Publication type:

Letter to the Editor

Pharmacological Improvement of Cystic Fibrosis Transmembrane Conductance Regulator Function Rescues Airway Epithelial Homeostasis and Host Defense in Children with Cystic Fibrosis.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2024, v. 209, n. 11, p. 1338, doi. 10.1164/rccm.202310-1836OC

By:

Loske, Jennifer;
Völler, Mirjam;
Lukassen, Sören;
Stahl, Mirjam;
Thürmann, Loreen;
Seegebarth, Anke;
Röhmel, Jobst;
Wisniewski, Sebastian;
Messingschlager, Marey;
Lorenz, Stephan;
Klages, Sven;
Eils, Roland;
Lehmann, Irina;
Mall, Marcus A.;
Graeber, Simon Y.;
Trump, Saskia

Publication type:

Article

Effects of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Lung Clearance Index and Magnetic Resonance Imaging in Patients with Cystic Fibrosis and One or Two Alleles.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2022, v. 206, n. 3, p. 311, doi. 10.1164/rccm.202201-0219OC

By:

Graeber, Simon Y.;
Renz, Diane M.;
Stahl, Mirjam;
Pallenberg, Sophia T.;
Sommerburg, Olaf;
Naehrlich, Lutz;
Berges, Julian;
Dohna, Martha;
Ringshausen, Felix C.;
Doellinger, Felix;
Vitzthum, Constanze;
Röhmel, Jobst;
Allomba, Christine;
Hämmerling, Susanne;
Barth, Sandra;
Rückes-Nilges, Claudia;
Wielpütz, Mark O.;
Hansen, Gesine;
Vogel-Claussen, Jens;
Tümmler, Burkhard

Publication type:

Article

Effects of Elexacaftor/Tezacaftor/Ivacaftor Therapy on CFTR Function in Patients with Cystic Fibrosis and One or Two Alleles.

Published in:

2022

By:

Graeber, Simon Y.;
Vitzthum, Constanze;
Pallenberg, Sophia T.;
Naehrlich, Lutz;
Stahl, Mirjam;
Rohrbach, Alexander;
Drescher, Marika;
Minso, Rebecca;
Ringshausen, Felix C.;
Rueckes-Nilges, Claudia;
Klajda, Jan;
Berges, Julian;
Yin Yu;
Scheuermann, Heike;
Hirtz, Stephanie;
Sommerburg, Olaf;
Dittrich, Anna-Maria;
Tümmler, Burkhard;
Mall, Marcus A.;
Yu, Yin

Publication type:

journal article

Effects of Elexacaftor/Tezacaftor/Ivacaftor Therapy on CFTR Function in Patients with Cystic Fibrosis and One or Two F508del Alleles.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2022, v. 205, n. 5, p. E1, doi. 10.1164/rccm.202110-2249oc

By:

Graeber, Simon Y.;
Vitzthum, Constanze;
Pallenberg, Sophia T.;
Naehrlich, Lutz;
Stahl, Mirjam;
Rohrbach, Alexander;
Drescher, Marika;
Minso, Rebecca;
Ringshausen, Felix C.;
Rueckes-Nilges, Claudia;
Klajda, Jan;
Berges, Julian;
Yin Yu;
Scheuermann, Heike;
Hirtz, Stephanie;
Sommerburg, Olaf;
Dittrich, Anna-Maria;
Tümmler, Burkhard;
Mall, Marcus A.

Publication type:

Article

Magnetic Resonance Imaging Detects Progression of Lung Disease and Impact of Newborn Screening in Preschool Children with Cystic Fibrosis.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2021, v. 204, n. 8, p. E1, doi. 10.1164/rccm.202102-0278oc

By:

Stahl, Mirjam;
Steinke, Eva;
Graeber, Simon Y.;
Joachim, Cornelia;
Seitz, Christoph;
Kauczor, Hans-Ulrich;
Eichinger, Monika;
Hämmerling, Susanne;
Sommerburg, Olaf;
Wielpütz, Mark O.;
Mall, Marcus A.

Publication type:

Article

Magnetic Resonance Imaging Detects Progression of Lung Disease and Impact of Newborn Screening in Preschool Children with Cystic Fibrosis.

Published in:

2021

By:

Stahl, Mirjam;
Steinke, Eva;
Graeber, Simon Y.;
Joachim, Cornelia;
Seitz, Christoph;
Kauczor, Hans-Ulrich;
Eichinger, Monika;
Hämmerling, Susanne;
Sommerburg, Olaf;
Wielpüz, Mark O.;
Mall, Marcus A.;
Wielpütz, Mark O

Publication type:

journal article

Comparison of Organoid Swelling and Biomarkers of CFTR Function to Determine Effects of Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for the F508del Mutation.

Published in:

2020

By:

Graeber, Simon Y.;
van Mourik, Peter;
Vonk, Annelotte M.;
Kruisselbrink, Evelien;
Hirtz, Stephanie;
van der Ent, Cornelis K.;
Mall, Marcus A.;
Beekman, Jeffrey M

Publication type:

research

Preventive Inhalation of Hypertonic Saline in Infants with Cystic Fibrosis (PRESIS). A Randomized, Double-Blind, Controlled Study.

Published in:

2019

By:

Stahl, Mirjam;
Wielpütz, Mark O;
Ricklefs, Isabell;
Dopfer, Christian;
Barth, Sandra;
Schlegtendal, Anne;
Graeber, Simon Y;
Sommerburg, Olaf;
Diekmann, Gesa;
Hüsing, Johannes;
Koerner-Rettberg, Cordula;
Nährlich, Lutz;
Dittrich, Anna-Maria;
Kopp, Matthias V;
Mall, Marcus A

Publication type:

journal article

Effects of Lumacaftor-Ivacaftor Therapy on Cystic Fibrosis Transmembrane Conductance Regulator Function in Phe508del Homozygous Patients with Cystic Fibrosis.

Published in:

2018

By:

Graeber, Simon Y.;
Dopfer, Christian;
Naehrlich, Lutz;
Gyulumyan, Lena;
Scheuermann, Heike;
Hirtz, Stephanie;
Wege, Sabine;
Mairbäurl, Heimo;
Dorda, Marie;
Hyde, Rebecca;
Bagheri-Hanson, Azadeh;
Rueckes-Nilges, Claudia;
Fischer, Sebastian;
Mall, Marcus A.;
Tümmler, Burkhard

Publication type:

journal article

Comparison of Lung Clearance Index and Magnetic Resonance Imaging for Assessment of Lung Disease in Children with Cystic Fibrosis.

Published in:

2017

By:

Stahl, Mirjam;
Wielpütz, Mark O.;
Graeber, Simon Y.;
Joachim, Cornelia;
Sommerburg, Olaf;
Kauczor, Hans-Ulrich;
Puderbach, Michael;
Eichinger, Monika;
Mall, Marcus A.

Publication type:

journal article

Intestinal Current Measurements Detect Activation of Mutant CFTR in Patients with Cystic Fibrosis with the G551D Mutation Treated with Ivacaftor.

Published in:

2015

By:

Graeber, Simon Y.;
Hug, Martin J.;
Sommerburg, Olaf;
Hirtz, Stephanie;
Hentschel, Julia;
Heinzmann, Andrea;
Dopfer, Christian;
Schulz, Angela;
Mainz, Jochen G.;
Tümmler, Burkhard;
Mall, Marcus A.

Publication type:

Letter

Multicystic Interstitial Lung Disease Due to a Novel Biallelic C‐C Chemokine Receptor Type 2 Variant.

Published in:

Pediatric Pulmonology, 2025, v. 60, n. 5, p. 1, doi. 10.1002/ppul.71135

By:

Herkner, Moritz;
Rapp, Christina;
Graeber, Simon Y.;
Marx, Charlotte;
Rambuscheck, Carlotta;
Reu‐Hofer, Simone;
Emiralioglu, Nagehan;
Kiper, Nural;
Gilea, Alexandru I.;
Notaroberto, Ilenia;
Baruffini, Enrico;
Temmesfeld‐Wollbrück, Bettina;
Klein, Christoph;
Wen, Han;
Stahl, Mirjam;
Griese, Matthias;
Gothe, Florian

Publication type:

Article

Potential of Intestinal Current Measurement for Personalized Treatment of Patients with Cystic Fibrosis.

Published in:

Journal of Personalized Medicine, 2021, v. 11, n. 5, p. 384, doi. 10.3390/jpm11050384

By:

Graeber, Simon Y.;
Vitzthum, Constanze;
Mall, Marcus A.;
van der Ent, Cornelis K.;
Heijerman, Harry G. M.

Publication type:

Article

Perinatal dysfunction of innate immunity in cystic fibrosis.

Published in:

Science Translational Medicine, 2025, v. 17, n. 782, p. 1, doi. 10.1126/scitranslmed.adk9145

By:

Jaudas, Florian;
Bartenschlager, Florian;
Shashikadze, Bachuki;
Santamaria, Gianluca;
Reichart, Daniel;
Schnell, Alexander;
Stöckl, Jan Bernd;
Degroote, Roxane L.;
Cambra, Josep M.;
Graeber, Simon Y.;
Bähr, Andrea;
Kartmann, Heike;
Stefanska, Monika;
Liu, Huan;
Naumann-Bartsch, Nora;
Bruns, Heiko;
Berges, Johannes;
Hanselmann, Lea;
Stirm, Michael;
Krebs, Stefan

Publication type:

Article

Personalized CFTR Modulator Therapy for G85E and N1303K Homozygous Patients with Cystic Fibrosis.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 15, p. 12365, doi. 10.3390/ijms241512365

By:

Graeber, Simon Y.;
Balázs, Anita;
Ziegahn, Niklas;
Rubil, Tihomir;
Vitzthum, Constanze;
Piehler, Linus;
Drescher, Marika;
Seidel, Kathrin;
Rohrbach, Alexander;
Röhmel, Jobst;
Thee, Stephanie;
Duerr, Julia;
Mall, Marcus A.;
Stahl, Mirjam

Publication type:

Article

Lack of Neutrophil Elastase Reduces Inflammation, Mucus Hypersecretion, and Emphysema, but Not Mucus Obstruction, in Mice with Cystic Fibrosis-like Lung Disease.

Published in:

2014

By:

Gehrig, Stefanie;
Duerr, Julia;
Weitnauer, Michael;
Wagner, Claudius J;
Graeber, Simon Y;
Schatterny, Jolanthe;
Hirtz, Stephanie;
Belaaouaj, Abderrazzaq;
Dalpke, Alexander H;
Schultz, Carsten;
Mall, Marcus A

Publication type:

Journal Article

Lack of Neutrophil Elastase Reduces Inflammation, Mucus Hypersecretion, and Emphysema, but Not Mucus Obstruction, in Mice with Cystic Fibrosis-like Lung Disease.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2014, v. 189, n. 9, p. 1082, doi. 10.1164/rccm.201311-1932oc

By:

Gehrig, Stefanie;
Duerr, Julia;
Weitnauer, Michael;
Wagner, Claudius J.;
Graeber, Simon Y.;
Schatterny, Jolanthe;
Hirtz, Stephanie;
Belaaouaj, Abderrazzaq;
Dalpke, Alexander H.;
Schultz, Garsten;
Mall, Marcus A.

Publication type:

Article

Ion mobility-tandem mass spectrometry of mucin-type O-glycans.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46825-4

By:

Bechtella, Leïla;
Jin Chunsheng;
Fentker, Kerstin;
Ertürk, Güney R.;
Safferthal, Marc;
Polewski, Łukasz;
Götze, Michael;
Graeber, Simon Y.;
Vos, Gaël M.;
Struwe, Weston B.;
Mall, Marcus A.;
Mertins, Philipp;
Karlsson, Niclas G.;
Pagel, Kevin

Publication type:

Article

Polyglycerol‐Based Mucus‐Inspired Hydrogels.

Published in:

Macromolecular Rapid Communications, 2021, v. 42, n. 20, p. 1, doi. 10.1002/marc.202100303

By:

Sharma, Antara;
Thongrom, Boonya;
Bhatia, Sumati;
von Lospichl, Benjamin;
Addante, Annalisa;
Graeber, Simon Y.;
Lauster, Daniel;
Mall, Marcus A.;
Gradzielski, Michael;
Haag, Rainer

Publication type:

Article

Progress of personalized medicine of cystic fibrosis in the times of efficient CFTR modulators.

Published in:

Molecular & Cellular Pediatrics, 2025, v. 12, n. 1, p. 1, doi. 10.1186/s40348-025-00194-0

By:

Tümmler, Burkhard;
Pallenberg, Sophia Theres;
Dittrich, Anna-Maria;
Graeber, Simon Y.;
Naehrlich, Lutz;
Sommerburg, Olaf;
Mall, Marcus A.

Publication type:

Article

CFTR Modulator Therapy with Lumacaftor/Ivacaftor Alters Plasma Concentrations of Lipid-Soluble Vitamins A and E in Patients with Cystic Fibrosis.

Published in:

Antioxidants, 2021, v. 10, n. 3, p. 483, doi. 10.3390/antiox10030483

By:

Sommerburg, Olaf;
Hämmerling, Susanne;
Schneider, S. Philipp;
Okun, Jürgen;
Langhans, Claus-Dieter;
Leutz-Schmidt, Patricia;
Wielpütz, Mark O.;
Siems, Werner;
Gräber, Simon Y.;
Mall, Marcus A.;
Stahl, Mirjam;
Bendich, Adrianne

Publication type:

Article

Effects of lumacaftor--ivacaftor therapy on cystic fibrosis transmembrane conductance regulator function in F508del homozygous patients with cystic fibrosis aged 2-11 years.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1188051

By:

Berges, Julian;
Graeber, Simon Y.;
Hämmerling, Susanne;
Yin Yu;
Krümpelmann, Arne;
Stahl, Mirjam;
Hirtz, Stephanie;
Scheuermann, Heike;
Mall, Marcus A.;
Sommerburg, Olaf

Publication type:

Article

Effects of elexacaftor/tezacaftor/ ivacaftor therapy on mental health of patients with cystic fibrosis.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1179208

By:

Piehler, Linus;
Thalemann, Ralf;
Lehmann, Christine;
Thee, Stephanie;
Röhmel, Jobst;
Syunyaeva, Zulfiya;
Stahl, Mirjam;
Mall, Marcus A.;
Graeber, Simon Y.

Publication type:

Article

Long-term effects of lumacaftor/ivacaftor on paranasal sinus abnormalities in children with cystic fibrosis detected with magnetic resonance imaging.

Published in:

Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1161891

By:

Wucherpfennig, Lena;
Wuennemann, Felix;
Eichinger, Monika;
Seitz, Angelika;
Baumann, Ingo;
Stahl, Mirjam;
Graeber, Simon Y.;
Shengkai Zhao;
Jaehi Chung;
Schenk, Jens-Peter;
Alrajab, Abdulsattar;
Kauczor, Hans-Ulrich;
Mall, Marcus A.;
Sommerburg, Olaf;
Wielpütz, Mark O.

Publication type:

Article

Comparison of Microbiomes from Different Niches of Upper and Lower Airways in Children and Adolescents with Cystic Fibrosis.

Published in:

PLoS ONE, 2015, v. 10, n. 1, p. 1, doi. 10.1371/journal.pone.0116029

By:

Boutin, Sébastien;
Graeber, Simon Y.;
Weitnauer, Michael;
Panitz, Jessica;
Stahl, Mirjam;
Clausznitzer, Diana;
Kaderali, Lars;
Einarsson, Gisli;
Tunney, Michael M.;
Elborn, J. Stuart;
Mall, Marcus A.;
Dalpke, Alexander H.

Publication type:

Article

Identification and Characterization of a Rare Exon 22 Duplication in CFTR in Two Families.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4487, doi. 10.3390/ijms26104487

By:

Ahting, Simone;
Henn, Constance;
vom Hove, Maike;
Strehlow, Vincent;
Duffek, Patricia;
Behrendt, Sophie;
Drukewitz, Stephan;
Berger, Jasmin;
Graeber, Simon Y.;
Hentschel, Julia

Publication type:

Article

Automated lung segmentation on chest MRI in children with cystic fibrosis.

Published in:

Frontiers in Medicine, 2024, p. 1, doi. 10.3389/fmed.2024.1401473

By:

Ringwald, Friedemann G.;
Wucherpfennig, Lena;
Hagen, Niclas;
Mücke, Jonas;
Kaletta, Sebastian;
Eichinger, Monika;
Stahl, Mirjam;
Triphan, Simon M. F.;
Leutz-Schmidt, Patricia;
Gestewitz, Sonja;
Graeber, Simon Y.;
Kauczor, Hans-Ulrich;
Alrajab, Abdulsattar;
Schenk, Jens-Peter;
Sommerburg, Olaf;
Mall, Marcus A.;
Knaup, Petra;
Wielpütz, Mark O.;
Eisenmann, Urs

Publication type:

Article

Changes in Microbiome Dominance Are Associated With Declining Lung Function and Fluctuating Inflammation in People With Cystic Fibrosis.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.885822

By:

Frey, Dario L.;
Bridson, Calum;
Dittrich, Susanne;
Graeber, Simon Y.;
Stahl, Mirjam;
Wege, Sabine;
Herth, Felix;
Sommerburg, Olaf;
Schultz, Carsten;
Dalpke, Alexander;
Mall, Marcus A.;
Boutin, Sébastien

Publication type:

Article

Longitudinal Magnetic Resonance Imaging of Changes in Lung Morphology and Perfusion in Children with Cystic Fibrosis from Infancy through Adolescence.

Published in:

Annals of the American Thoracic Society, 2025, v. 22, n. 1, p. 93, doi. 10.1513/AnnalsATS.202404-396OC

By:

Wielpütz, Mark O.;
Stahl, Mirjam;
Triphan, Simon M. F.;
Wucherpfennig, Lena;
Leutz-Schmidt, Patricia;
Gestewitz, Sonja;
Steinke, Eva;
Graeber, Simon Y.;
Kauczor, Hans-Ulrich;
Eichinger, Monika;
Puderbach, Michael U.;
Alrajab, Abdulsattar;
Schenk, Jens-Peter;
Sommerburg, Olaf;
Mall, Marcus A.

Publication type:

Article

Longitudinal Magnetic Resonance Imaging Detects Onset and Progression of Chronic Rhinosinusitis from Infancy to School Age in Cystic Fibrosis.

Published in:

Annals of the American Thoracic Society, 2023, v. 20, n. 5, p. 687, doi. 10.1513/AnnalsATS.202209-763OC

By:

Wucherpfennig, Lena;
Wuennemann, Felix;
Eichinger, Monika;
Schmitt, Niclas;
Seitz, Angelika;
Baumann, Ingo;
Stahl, Mirjam;
Graeber, Simon Y.;
Jaehi Chung;
Schenk, Jens-Peter;
Alrajab, Abdulsattar;
Kauczor, Hans-Ulrich;
Mall, Marcus A.;
Sommerburg, Olaf;
Wielpütz, Mark O.

Publication type:

Article

Effects of Lumacaftor-Ivacaftor on Lung Clearance Index, Magnetic Resonance Imaging, and Airway Microbiome in Phe508del Homozygous Patients with Cystic Fibrosis.

Published in:

2021

By:

Graeber, Simon Y.;
Boutin, Sébastien;
Wielpütz, Mark O.;
Joachim, Cornelia;
Frey, Dario L.;
Wege, Sabine;
Sommerburg, Olaf;
Kauczor, Hans-Ulrich;
Stahl, Mirjam;
Dalpke, Alexander H.;
Mall, Marcus A.

Publication type:

journal article

Comparison of Oropharyngeal Microbiota from Children with Asthma and Cystic Fibrosis.

Published in:

Mediators of Inflammation, 2017, p. 1, doi. 10.1155/2017/5047403

By:

Boutin, Sébastien;
Depner, Martin;
Stahl, Mirjam;
Graeber, Simon Y.;
Dittrich, Susanne A.;
Legatzki, Antje;
von Mutius, Erika;
Mall, Marcus;
Dalpke, Alexander H.

Publication type:

Article