Works by Gorobets, Nikolay Yu.

Results: 11

One-pot Synthesis of Benzo[4,5]imidazo[1,2-a]pyridine Derivatives in Aqueous Conditions.

Published in:

Journal of Heterocyclic Chemistry, 2017, v. 54, n. 1, p. 753, doi. 10.1002/jhet.2617

By:

Vodolazhenko, Maria A.;
Mykhailenko, Anastasiia E.;
Gorobets, Nikolay Yu.;
Desenko, Sergey M.

Publication type:

Article

Three possible products from the reactions of gewald's amide with aromatic aldehydes.

Published in:

Journal of Heterocyclic Chemistry, 2008, v. 45, n. 2, p. 573, doi. 10.1002/jhet.5570450243

By:

Dzhavakhishvili, Sergey G.;
Gorobets, Nikolay Yu.;
Musatov, Vladimir I.;
Desenko, Sergey M.;
Paponov, Boris V.

Publication type:

Article

Generation of 500-Member Library of 10-Alkyl-2-R1,3-R2-4,10-Dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones.

Published in:

Molecules, 2009, v. 14, n. 12, p. 5223, doi. 10.3390/molecules14125223

By:

Sirko, Svetlana M.;
Gorobets, Nikolay Yu.;
Musatov, Vladimir I.;
Desenko, Sergey M.

Publication type:

Article

5-(5-Bromo-2-hydroxy-3-methoxyphenyl)-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol.

Published in:

Molbank, 2016, v. 2016, n. 2, p. m898, doi. 10.3390/M898

By:

Kondratiuk, Michael;
Gorobets, Nikolay Yu.;
Sedash, Yuriy V.;
Gümüş, Mustafa K.;
Desenko, Sergey M.

Publication type:

Article

Computational study of novel inhibitory molecule, 1-(4-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)piperazin-1-yl)-3-phenylurea, with high potential to competitively block ATP binding to the RNA dependent RNA polymerase of SARS-CoV-2 virus.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 20, p. 10162, doi. 10.1080/07391102.2021.1940281

By:

Sharma, Prem Prakash;
Kumar, Sumit;
Srivastava, Sukrit;
Srivastava, Mitul;
Jee, Babban;
Gorobets, Nikolay Yu.;
Kumar, Dhruv;
Kumar, Mukesh;
Asthana, Shailendra;
Zhang, Peng;
Poonam;
Zoltner, Martin;
Rathi, Brijesh

Publication type:

Article

In Vitro Cytotoxicity of Methano[1,2,4]Triazolo-[1,5-C][1,3,5]Benzoxadiazocine Derivatives and Their Effects on Nitrite and Prostaglandin E2 (PGE2) Levels.

Published in:

Pharmaceutical Chemistry Journal, 2022, v. 56, n. 6, p. 769, doi. 10.1007/s11094-022-02708-w

By:

Doğan, İnci Selin;
Gümüş, Mustafa Kemal;
Gorobets, Nikolay Yu.;
Reis, Rengin;
Orak, Duygu;
Sipahi, Hande;
Sari, Suat;
Chebanov, Valentyn A.

Publication type:

Article

Dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-4-ones as a new class of CK2 inhibitors.

Published in:

Molecular Diversity, 2018, v. 22, n. 4, p. 991, doi. 10.1007/s11030-018-9836-1

By:

Protopopov, Mykola V.;
Ostrynska, Olga V.;
Starosyla, Sergiy A.;
Vodolazhenko, Maria A.;
Sirko, Svetlana M.;
Gorobets, Nikolay Yu.;
Bdzhola, Volodymyr;
Desenko, Sergey M.;
Yarmoluk, Sergiy M.

Publication type:

Article

Difference between 1H NMR signals of primary amide protons as a simple spectral index of the amide intramolecular hydrogen bond strength.

Published in:

Journal of Physical Organic Chemistry, 2012, v. 25, n. 4, p. 287, doi. 10.1002/poc.1910

By:

Gorobets, Nikolay Yu.;
Yermolayev, Sergey A.;
Gurley, Thomas;
Gurinov, Andrey A.;
Tolstoy, Peter M.;
Shenderovich, Ilya G.;
Leadbeater, Nicholas E.

Publication type:

Article

Competing transformations of 2-cyanoacetanilides in reactions with derivatives of ethoxymethylenemalonic acid.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2012, p. 398

By:

Tkachova, Valeriya P.;
Gorobets, Nikolay Yu.;
Tkachov, Roman P.;
Musatov, Vladimir I.;
Dyachenko, Vladimir D.

Publication type:

Article

Reactions of diethyl 2-(ethoxymethylene)malonate with 2-cyanoacetanilides: unexpected transfer of the ethoxymethylene moiety.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2010, p. 254

By:

Tkachova, Valeriya P.;
Gorobets, Nikolay Yu.;
Tkachov, Roman P.;
Dyachenko, Oleksandr D.;
Rusanov, Eduard B.;
Dyachenko, Vladimir D.

Publication type:

Article

Structure of the intermediate in the synthesis of 6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2009, p. 23

By:

Gorobets, Nikolay Yu.;
Sedash, Yuriy V.;
Shishkina, Svetlana V.;
Shishkin, Oleg V.;
Yermolayev, Sergey A.;
Desenko, Sergey M.

Publication type:

Article

Works by Gorobets, Nikolay Yu.

One-pot Synthesis of Benzo[4,5]imidazo[1,2-a]pyridine Derivatives in Aqueous Conditions.

Three possible products from the reactions of gewald's amide with aromatic aldehydes.

Generation of 500-Member Library of 10-Alkyl-2-R<sup>1</sup>,3-R<sup>2</sup>-4,10-Dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones.

5-(5-Bromo-2-hydroxy-3-methoxyphenyl)-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol.

Computational study of novel inhibitory molecule, 1-(4-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)piperazin-1-yl)-3-phenylurea, with high potential to competitively block ATP binding to the RNA dependent RNA polymerase of SARS-CoV-2 virus.

In Vitro Cytotoxicity of Methano[1,2,4]Triazolo-[1,5-C][1,3,5]Benzoxadiazocine Derivatives and Their Effects on Nitrite and Prostaglandin E2 (PGE2) Levels.

Dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-4-ones as a new class of CK2 inhibitors.

Difference between <sup>1</sup>H NMR signals of primary amide protons as a simple spectral index of the amide intramolecular hydrogen bond strength.

Competing transformations of 2-cyanoacetanilides in reactions with derivatives of ethoxymethylenemalonic acid.

Reactions of diethyl 2-(ethoxymethylene)malonate with 2-cyanoacetanilides: unexpected transfer of the ethoxymethylene moiety.

Structure of the intermediate in the synthesis of 6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile.