Works by Goralski, Kerry B.

Results: 26

Downregulation of mdr 1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin.

Published in:

British Journal of Pharmacology, 2003, v. 139, n. 1, p. 35, doi. 10.1038/sj.bjp.0705227

By:

Goralski, Kerry B.;
Hartmann, Georgy;
Piquette-Miller, Micheline;
Renton, Kenneth W.

Publication type:

Article

Jadomycin B Acts Synergistically with NSAIDs to Produce Cytotoxic Effects in Human Breast Cancer Cells in vitro.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2942

By:

McKeown, Brendan T.;
Goralski, Kerry B.

Publication type:

Article

Suppression of NNK Metabolism by Anthocyanin-Rich Haskap Berry Supplementation Through Modulation of P450 Enzymes.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 12, p. 1615, doi. 10.3390/ph17121615

By:

Amararathna, Madumani;
Hoskin, David W.;
Goralski, Kerry B.;
Rupasinghe, H. P. Vasantha

Publication type:

Article

Biliopancreatic diversion with duodenal switch modifies plasma chemerin in early and late post-operative periods.

Published in:

2015

By:

Parlee, Sebastian D;
Wang, Yan;
Poirier, Paul;
Lapointe, Marc;
Martin, Julie;
Bastien, Marjorie;
Cianflone, Katherine;
Goralski, Kerry B

Publication type:

journal article

Biliopancreatic diversion with duodenal switch modifies plasma chemerin in early and late post-operative periods.

Published in:

Obesity (19307381), 2015, v. 23, n. 6, p. 1201, doi. 10.1002/oby.21084

By:

Parlee, Sebastian D.;
Wang, Yan;
Poirier, Paul;
Lapointe, Marc;
Martin, Julie;
Bastien, Marjorie;
Cianflone, Katherine;
Goralski, Kerry. B.

Publication type:

Article

Jadomycins: A potential chemotherapy for multi-drug resistant metastatic breast cancer.

Published in:

Pharmacology Research & Perspectives, 2021, v. 9, n. 6, p. 1, doi. 10.1002/prp2.886

By:

Bonitto, Esther P.;
McKeown, Brendan T.;
Goralski, Kerry B.

Publication type:

Article

Jadomycin breast cancer cytotoxicity is mediated by a copper-dependent, reactive oxygen species-inducing mechanism.

Published in:

Pharmacology Research & Perspectives, 2015, v. 3, n. 2, p. n/a, doi. 10.1002/prp2.110

By:

Hall, Steven R.;
Blundon, Heather L.;
Ladda, Matthew A.;
Robertson, Andrew W.;
Martinez‐Farina, Camilo F.;
Jakeman, David L.;
Goralski, Kerry B.

Publication type:

Article

More Than an Adipokine: The Complex Roles of Chemerin Signaling in Cancer.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 19, p. 4778, doi. 10.3390/ijms20194778

By:

Goralski, Kerry B.;
Jackson, Ashley E.;
McKeown, Brendan T.;
Sinal, Christopher J.

Publication type:

Article

Isolation of a jadomycin incorporating L-ornithine, analysis of antimicrobial activity and jadomycin reactive oxygen species (ROS) generation in MDA-MB-231 breast cancer cells.

Published in:

Journal of Antibiotics, 2018, v. 71, n. 8, p. 722, doi. 10.1038/s41429-018-0060-0

By:

Forget, Stephanie M.;
Robertson, Andrew W.;
Hall, Steven R.;
MacLeod, Jeanna M.;
Overy, David P.;
Kerr, Russell G.;
Goralski, Kerry B.;
Jakeman, David L.

Publication type:

Article

Systematic review of Health Canada approved clinical therapeutic trials for the treatment or prevention of coronavirus disease 2019 (COVID-19).

Published in:

Canadian Journal of Physiology & Pharmacology, 2025, v. 103, n. 5, p. 146, doi. 10.1139/cjpp-2024-0055

By:

Diab, Antonios M.;
Stack, Hailey M.;
McKeown, Brendan T.;
Carleton, Bruce C.;
Goralski, Kerry B.

Publication type:

Article

Pharmacological interactions of jadomycin B with topoisomerase poisons in MDA-MB-231 human breast cancer cells.

Published in:

Canadian Journal of Physiology & Pharmacology, 2025, v. 103, n. 1, p. 36, doi. 10.1139/cjpp-2024-0232

By:

McKeown, Brendan T.;
Goralski, Kerry B.

Publication type:

Article

Correction: Pilot study of jadomycin B pharmacokinetics and anti-tumoral effects in zebrafish larvae and mouse breast cancer xenograft models.

Published in:

2023

By:

McKeown, Brendan T.;
Relja, Nicholas J.;
Hall, Steven R.;
Gebremeskel, Simon;
MacLeod, Jeanna M.;
Veinotte, Chansey J.;
Bennett, Leah G.;
Ohlund, Leanne B.;
Sleno, Lekha;
Jakeman, David L.;
Berman, Jason N.;
Johnston, Brent;
Goralski, Kerry B.

Publication type:

Correction Notice

Pilot study of jadomycin B pharmacokinetics and anti-tumoral effects in zebrafish larvae and mouse breast cancer xenograft models.

Published in:

Canadian Journal of Physiology & Pharmacology, 2022, v. 100, n. 11, p. 1065, doi. 10.1139/cjpp-2022-0152

By:

McKeown, Brendan T.;
Relja, Nicholas J.;
Hall, Steven R.;
Gebremeskel, Simon;
MacLeod, Jeanna M.;
Veinotte, Chansey J.;
Bennett, Leah G.;
Ohlund, Leanne B.;
Sleno, Lekha;
Jakeman, David L.;
Berman, Jason N.;
Johnston, Brent;
Goralski, Kerry B.

Publication type:

Article

COVID-19 pathophysiology and pharmacology: what do we know and how did Canadians respond? A review of Health Canada authorized clinical vaccine and drug trials.

Published in:

Canadian Journal of Physiology & Pharmacology, 2021, v. 99, n. 6, p. 577, doi. 10.1139/cjpp-2021-0038

By:

Diab, Antonios M.;
Carleton, Bruce C.;
Goralski, Kerry B.

Publication type:

Article

Chipping away at gallstones.

Published in:

Nature Medicine, 2004, v. 10, n. 12, p. 1301, doi. 10.1038/nm1204-1301

By:

Goralski, Kerry B.;
Sinal, Christopher J.

Publication type:

Article

Type 2 diabetes and cardiovascular disease: getting to the fat of the matter.

Published in:

Canadian Journal of Physiology & Pharmacology, 2007, v. 85, n. 1, p. 113, doi. 10.1139/Y06-092

By:

Goralski, Kerry B.;
Sinal, Christopher J.

Publication type:

Article

Perturbation of rat renal tubule transport of the organic cation amantadine in recent onset streptozotocin-induced diabetes and in uninephrectomy.

Published in:

Canadian Journal of Physiology & Pharmacology, 2001, v. 79, n. 1, p. 18, doi. 10.1139/y00-104

By:

Goralski, Kerry B;
Stupack, Dwayne G;
Hatch, Grant M;
Sitar, Daniel S

Publication type:

Article

The impact of COVID-19 infection on cytochrome P450 3A4-mediated drug metabolism and drug interactions.

Published in:

2023

By:

Villemure, Samuel;
Trenaman, Shanna C;
Goralski, Kerry B

Publication type:

Editorial

Characterization of the anticancer pharmacology of novel jadomycin molecules.

Published in:

FASEB Journal, 2013, v. 27, p. 671.3, doi. 10.1096/fasebj.27.1_supplement.671.3

By:

Hall, Steven Robert;
Robertson, Andrew;
Jakeman, David L.;
Goralski, Kerry B.

Publication type:

Article

Metabolism and pharmacokinetics of a novel polyphenol fatty acid ester phloridzin docosahexaenoate in Balb/c female mice.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-78369-0

By:

Fernando, Wasundara;
Goralski, Kerry B.;
Hoskin, David W.;
Rupasinghe, H. P. Vasantha

Publication type:

Article

Elastase and Tryptase Govern TNFα-Mediated Production of Active Chemerin by Adipocytes.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051072

By:

Parlee, Sebastian D.;
McNeil, Jenna O.;
Muruganandan, Shanmugam;
Sinal, Christopher J.;
Goralski, Kerry B.

Publication type:

Article

Paradoxical Cyclosporine A Requirements in Pediatric Renal Transplants Receiving High-Dose Steroids.

Published in:

Journal of Clinical Pharmacology, 2005, v. 45, n. 2, p. 161, doi. 10.1177/0091270004271403

By:

Hardy, Karolyn W.;
Crocker, John F. S.;
McLellan, Heather;
Goralski, Kerry B.;
Renton, Ken W.;
Acott, Philip D.

Publication type:

Article

Les effets d’une réaction inflammatoire induite par chirurgie sur la distribution de morphine et de ses métabolites dans le liquide céphalorachidien : une étude observationnelle.

Published in:

2017

By:

Wang, Yan;
Goralski, Kerry;
Roberts, Derek;
Landry, Kathryn;
Issa, Mark;
Sleno, Lekha;
Julien, Lisa;
Wood, Jeremy;
Hall, Richard;
Goralski, Kerry B;
Roberts, Derek J;
Issa, Mark E;
Julien, Lisa C;
Hall, Richard I

Publication type:

journal article

Antitumor Activity of Abnormal Cannabidiol and Its Analog O-1602 in Taxol-Resistant Preclinical Models of Breast Cancer.

Published in:

Frontiers in Pharmacology, 2019, p. 1, doi. 10.3389/fphar.2019.01124

By:

Tomko, Andrea;
O'Leary, Lauren;
Trask, Hilary;
Achenbach, John C.;
Hall, Steven R.;
Goralski, Kerry B.;
Ellis, Lee D.;
Dupré, Denis J.

Publication type:

Article

An evaluation of oral dabigatran etexilate pharmacokinetics and pharmacodynamics in hemodialysis.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 8, p. 901, doi. 10.1002/jcph.335

By:

Wilson, Jo‐Anne S.;
Goralski, Kerry B.;
Soroka, Steven D.;
Morrison, Matthew;
Mossop, Paula;
Sleno, Lekha;
Wang, Yan;
Anderson, David R.

Publication type:

Article

S100B as a biomarker of blood–brain barrier disruption after thoracoabdominal aortic aneurysm repair: a secondary analysis from a prospective cohort study.

Published in:

Canadian Journal of Anaesthesia / Journal Canadien d'Anesthésie, 2021, v. 68, n. 12, p. 1756, doi. 10.1007/s12630-021-02110-2

By:

Roberts, Derek J.;
Hall, Richard I.;
Wang, Yan;
Julien, Lisa C.;
Wood, Jeremy;
Goralski, Kerry B.

Publication type:

Article