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Sequence Analysis of Inducible, Replication-Competent Virus Reveals No Evidence of HIV-1 Evolution During Suppressive Antiviral Therapy, Indicating a Lack of Ongoing Viral Replication.
Published in:
Open Forum Infectious Diseases, 2024, v. 11, n. 5, p. 1, doi. 10.1093/ofid/ofae212
By:
- Lee, Sook-Kyung;
- Sondgeroth, Amy;
- Xu, Yinyan;
- Warren, Joanna;
- Zhou, Shuntai;
- Gilleece, Maria;
- Hauser, Blake M;
- Gay, Cynthia L;
- Kuruc, JoAnn D;
- Archin, Nancie M;
- Eron, Joseph J;
- Margolis, David M;
- Goonetilleke, Nilu;
- Swanstrom, Ronald
Publication type:
Article
Improved detection of latent Mycobacterium tuberculosis infection in HIV-1 seropositive individuals using cultured cellular assays.
Published in:
European Journal of Immunology, 2011, v. 41, n. 1, p. 255, doi. 10.1002/eji.201040296
By:
- Campion, Suzanne;
- Cohen, Myron S.;
- McMichael, Andrew J;
- Galvin, Shannon;
- Goonetilleke, Nilu
Publication type:
Article
The HIV-1 latent reservoir is largely sensitive to circulating T cells.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.57246
By:
- Warren, Joanna A.;
- Shuntai Zhou;
- Yinyan Xu;
- Moeser, Matthew J.;
- MacMillan, Daniel R.;
- Council, Olivia;
- Kirchherr, Jennifer;
- Sung, Julia M.;
- Roan, Nadia R.;
- Adimora, Adaora A.;
- Joseph, Sarah;
- Kuruc, JoAnn D.;
- Gay, Cynthia L.;
- Margolis, David M.;
- Archin, Nancie;
- Brumme, Zabrina L.;
- Swanstrom, Ronald;
- Goonetilleke, Nilu
Publication type:
Article
Harnessing CD8+ T Cells Under HIV Antiretroviral Therapy.
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00291
By:
- Warren, Joanna A.;
- Clutton, Genevieve;
- Goonetilleke, Nilu
Publication type:
Article
Reversion and T Cell Escape Mutations Compensate the Fitness Loss of a CD8+ T Cell Escape Mutant in Their Cognate Transmitted/Founder Virus.
Published in:
PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102734
By:
- Song, Hongshuo;
- Hora, Bhavna;
- Bhattacharya, Tanmoy;
- Goonetilleke, Nilu;
- Liu, Michael K. P.;
- Wiehe, Kevin;
- Li, Hui;
- Iyer, Shilpa S.;
- McMichael, Andrew J.;
- Perelson, Alan S.;
- Gao, Feng
Publication type:
Article
Comparison of Sexual Behavior and HIV Risk between Two HIV-1 Serodiscordant Couple Cohorts: The CHAVI 002 Stu.
Published in:
PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037727
By:
- Ritchie, Adam J.;
- Kuldanek, Kristin;
- Moodie, Zoe;
- Wang, Z. Maggie;
- Fox, Julie;
- Nsubuga, Rebecca N.;
- Legg, Kenneth;
- Birabwa, Esther F.;
- Kaleebu, Pontiano;
- McMichael, Andrew J.;
- Watera, Christine;
- Goonetilleke, Nilu;
- Fidler, Sarah
Publication type:
Article
The Magnitude and Kinetics of the Mucosal HIV-Specific CD8+ T Lymphocyte Response and Virus RNA Load in Breast Milk.
Published in:
PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023735
By:
- Mahlokozera, Tatenda;
- Kang, Helen H.;
- Goonetilleke, Nilu;
- Stacey, Andrea R.;
- Lovingood, Rachel V.;
- Denny, Thomas N.;
- Kalilani, Linda;
- Bunn, James E. G.;
- Meshnick, Steve R.;
- Borrow, Persephone;
- Letvin, Norman L.;
- Permar, Sallie R.
Publication type:
Article
Natural T Cell-mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study.
Published in:
2015
By:
- Hayward, Andrew C;
- Wang, Lili;
- Goonetilleke, Nilu;
- Fragaszy, Ellen B;
- Bermingham, Alison;
- Copas, Andrew;
- Dukes, Oliver;
- Millett, Elizabeth R C;
- Nazareth, Irwin;
- Nguyen-Van-Tam, Jonathan S;
- Watson, John M;
- Zambon, Maria;
- Johnson, Anne M;
- McMichael, Andrew J;
- Flu Watch Group
Publication type:
journal article
Natural T Cell-mediated Protection against Seasonal and Pandemic Influenza.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 191, n. 12, p. 1422, doi. 10.1164/rccm.201411-1988OC
By:
- Hayward, Andrew C.;
- Lili Wang;
- Goonetilleke, Nilu;
- Fragaszy, Ellen B.;
- Bermingham, Alison;
- Copas, Andrew;
- Dukes, Oliver;
- Millett, Elizabeth R. C.;
- Nazareth, Irwin;
- Nguyen-Van-Tam, Jonathan S.;
- Watson, John M.;
- Zambon, Maria;
- Johnson, Anne M.;
- McMichael, Andrew J.
Publication type:
Article
Blocking Formation of the Stable HIV Reservoir: A New Perspective for HIV-1 Cure.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01966
By:
- Goonetilleke, Nilu;
- Clutton, Genevieve;
- Swanstrom, Ron;
- Joseph, Sarah B.
Publication type:
Article
OMIP‐087: Thirty‐two parameter mass cytometry panel to assess human CD4 and CD8 T cell activation, memory subsets, and helper subsets.
Published in:
Cytometry. Part A, 2023, v. 103, n. 3, p. 184, doi. 10.1002/cyto.a.24707
By:
- Sponaugle, Alexis;
- Abad‐Fernandez, Maria;
- Goonetilleke, Nilu
Publication type:
Article
A Reproducible, Objective Method Using MitoTracker® Fluorescent Dyes to Assess Mitochondrial Mass in T Cells by Flow Cytometry.
Published in:
Cytometry. Part A, 2019, v. 95, n. 4, p. 450, doi. 10.1002/cyto.a.23705
By:
- Clutton, Genevieve;
- Mollan, Katie;
- Hudgens, Michael;
- Goonetilleke, Nilu
Publication type:
Article
The immune response during acute HIV-1 infection: clues for vaccine development.
Published in:
2010
By:
- McMichael, Andrew J.;
- Borrow, Persephone;
- Tomaras, Georgia D.;
- Goonetilleke, Nilu;
- Haynes, Barton F.
Publication type:
journal article
Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.
Published in:
eLife, 2024, p. 1, doi. 10.7554/eLife.94899
By:
- Semenova, Lesia;
- Yingfan Wang;
- Falcinelli, Shane;
- Archin, Nancie;
- Cooper-Volkheimer, Alicia D.;
- Margolis, David M.;
- Goonetilleke, Nilu;
- Murdoch, David M.;
- Rudin, Cynthia D.;
- Browne, Edward P.
Publication type:
Article
Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-61878-3
By:
- Gay, Cynthia L.;
- Kuruc, Joann D.;
- Falcinelli, Shane D.;
- Warren, Joanna A.;
- Reifeis, Sarah A.;
- Kirchherr, Jennifer L.;
- James, Katherine S.;
- Dewey, Morgan G.;
- Helms, Alyson;
- Allard, Brigitte;
- Stuelke, Erin;
- Gamble, Alicia;
- Plachco, Ana;
- Gorelick, Robert J.;
- Eron, Joseph J.;
- Hudgens, Michael;
- Garrido, Carolina;
- Goonetilleke, Nilu;
- DeBenedette, Mark A.;
- Tcherepanova, Irina Y.
Publication type:
Article
A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies.
Published in:
Retrovirology, 2017, v. 14, p. 1, doi. 10.1186/s12977-017-0371-4
By:
- Donglai Liu;
- Chu Wang;
- Hora, Bhavna;
- Tao Zuo;
- Goonetilleke, Nilu;
- Liu, Michael K. P.;
- Berrong, Mark;
- Ferrari, Guido;
- McMichael, Andrew J.;
- Bhattacharya, Tanmoy;
- Perelson, Alan S.;
- Feng Gao
Publication type:
Article
Interval dosing with the HDAC inhibitor vorinostat effectively reverses HIV latency.
Published in:
2017
By:
- Archin, Nancie M.;
- Kirchherr, Jennifer L.;
- Sung, Julia A. M.;
- Clutton, Genevieve;
- Sholtis, Katherine;
- Yinyan Xu;
- Allard, Brigitte;
- Stuelke, Erin;
- Kashuba, Angela D.;
- Kuruc, Joann D.;
- Eron, Joseph;
- Gay, Cynthia L.;
- Goonetilleke, Nilu;
- Margolis, David M.;
- Sung, Julia Am;
- Xu, Yinyan
Publication type:
journal article
Reliable Estimation of CD8 T Cell Inhibition of In Vitro HIV-1 Replication.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.666991
By:
- Xu, Yinyan;
- Weideman, Ann Marie;
- Abad-Fernandez, Maria;
- Mollan, Katie R.;
- Kallon, Sallay;
- Samir, Shahryar;
- Warren, Joanna A.;
- Clutton, Genevieve;
- Roan, Nadia;
- Adimora, Adaora A.;
- Archin, Nancie;
- Kuruc, JoAnn;
- Gay, Cindy;
- Hudgens, Michael G.;
- Goonetilleke, Nilu
Publication type:
Article
CD3 downregulation identifies high-avidity human CD8 T cells.
Published in:
Clinical & Experimental Immunology, 2024, v. 215, n. 3, p. 279, doi. 10.1093/cei/uxad124
By:
- Clutton, Genevieve T;
- Weideman, Ann Marie K;
- Mischell, Melissa A;
- Kallon, Sallay;
- Conrad, Shayla Z;
- Shaw, Fiona R;
- Warren, Joanna A;
- Lin, Lin;
- Kuruc, JoAnn D;
- Xu, Yinyan;
- Gay, Cynthia M;
- Armistead, Paul M;
- G. Hudgens, Michael;
- Goonetilleke, Nilu P
Publication type:
Article
Relative rate and location of intra-host HIV evolution to evade cellular immunity are predictable.
Published in:
Nature Communications, 2016, v. 7, n. 5, p. 11660, doi. 10.1038/ncomms11660
By:
- Barton, John P.;
- Goonetilleke, Nilu;
- Butler, Thomas C.;
- Walker, Bruce D.;
- McMichael, Andrew J.;
- Chakraborty, Arup K.
Publication type:
Article
The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation.
Published in:
Science Translational Medicine, 2019, v. 11, n. 513, p. 1, doi. 10.1126/scitranslmed.aaw5589
By:
- Abrahams, Melissa-Rose;
- Joseph, Sarah B.;
- Garrett, Nigel;
- Tyers, Lynn;
- Moeser, Matthew;
- Archin, Nancie;
- Council, Olivia D.;
- Matten, David;
- Zhou, Shuntai;
- Doolabh, Deelan;
- Anthony, Colin;
- Goonetilleke, Nilu;
- Karim, Salim Abdool;
- Margolis, David M.;
- Pond, Sergei Kosakovsky;
- Williamson, Carolyn;
- Swanstrom, Ronald
Publication type:
Article
Proof-of-Principle for Immune Control of Global HIV-1 Reactivation In Vivo.
Published in:
Clinical Infectious Diseases, 2015, v. 61, n. 1, p. 120, doi. 10.1093/cid/civ219
By:
- Smith, Nicola M. G.;
- Mlcochova, Petra;
- Watters, Sarah A.;
- Aasa-Chapman, Marlene M. I.;
- Rabin, Neil;
- Moore, Sally;
- Edwards, Simon G.;
- Garson, Jeremy A.;
- Grant, Paul R.;
- Ferns, R. Bridget;
- Kashuba, Angela;
- Mayor, Neema P.;
- Schellekens, Jennifer;
- Marsh, Steven G. E.;
- McMichael, Andrew J.;
- Perelson, Alan S.;
- Pillay, Deenan;
- Goonetilleke, Nilu;
- Gupta, Ravindra K.
Publication type:
Article
Cellular immune responses induced in cattle by heterologous prime–boost vaccination using recombinant viruses and bacille Calmette–Guérin.
Published in:
Immunology, 2004, v. 112, n. 3, p. 461, doi. 10.1111/j.1365-2567.2004.01903.x
By:
- Vordermeier, H. Martin;
- Rhodes, Shelley G.;
- Dean, Gillian;
- Goonetilleke, Nilu;
- Huygen, Kris;
- Hill, Adrian V. S.;
- Hewinson, R. Glyn;
- Gilbert, Sarah C.
Publication type:
Article
Vaccines: Underlying Principles of Design and Testing.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 4, p. 987, doi. 10.1002/cpt.2207
By:
- Kallon, Sallay;
- Samir, Shahryar;
- Goonetilleke, Nilu
Publication type:
Article
Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection.
Published in:
PLoS Pathogens, 2016, v. 12, n. 8, p. 1, doi. 10.1371/journal.ppat.1005805
By:
- Demers, Korey R.;
- Makedonas, George;
- Buggert, Marcus;
- Eller, Michael A.;
- Ratcliffe, Sarah J.;
- Goonetilleke, Nilu;
- Li, Chris K.;
- Eller, Leigh Anne;
- Rono, Kathleen;
- Maganga, Lucas;
- Nitayaphan, Sorachai;
- Kibuuka, Hannah;
- Routy, Jean-Pierre;
- Slifka, Mark K.;
- Haynes, Barton F.;
- McMichael, Andrew J.;
- Bernard, Nicole F.;
- Robb, Merlin L.;
- Betts, Michael R.
Publication type:
Article
Identification of Effective Subdominant Anti-HIV-1 CD8+ T Cells Within Entire Post-infection and Post-vaccination Immune Responses.
Published in:
PLoS Pathogens, 2015, v. 11, n. 2, p. 1, doi. 10.1371/journal.ppat.1004658
By:
- Hancock, Gemma;
- Yang, Hongbing;
- Yorke, Elisabeth;
- Wainwright, Emma;
- Bourne, Victoria;
- Frisbee, Alyse;
- Payne, Tamika L.;
- Berrong, Mark;
- Ferrari, Guido;
- Chopera, Denis;
- Hanke, Tomas;
- Mothe, Beatriz;
- Brander, Christian;
- McElrath, M. Juliana;
- McMichael, Andrew;
- Goonetilleke, Nilu;
- Tomaras, Georgia D.;
- Frahm, Nicole;
- Dorrell, Lucy
Publication type:
Article
Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection.
Published in:
PLoS Pathogens, 2011, v. 7, n. 2, p. 1, doi. 10.1371/journal.ppat.1001273
By:
- Ferrari, Guido;
- Korber, Bette;
- Goonetilleke, Nilu;
- Liu, Michael K. P.;
- Turnbull, Emma L.;
- Salazar-Gonzalez, Jesus F.;
- Hawkins, Natalie;
- Self, Steve;
- Watson, Sydeaka;
- Betts, Michael R.;
- Gay, Cynthia;
- McGhee, Kara;
- Pellegrino, Pierre;
- Williams, Ian;
- Tomaras, Georgia D.;
- Haynes, Barton F.;
- Gray, Clive M.;
- Borrow, Persephone;
- Roederer, Mario;
- McMichael, Andrew J.
Publication type:
Article
Sequential CCR5-Tropic HIV-1 Reactivation from Distinct Cellular Reservoirs following Perturbation of Elite Control.
Published in:
PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0158854
By:
- Watters, Sarah A.;
- Mlcochova, Petra;
- Maldarelli, Frank;
- Goonetilleke, Nilu;
- Pillay, Deenan;
- Gupta, Ravindra K.
Publication type:
Article
Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.
Published in:
2017
By:
- Kijak, Gustavo H.;
- Sanders-Buell, Eric;
- Chenine, Agnes-Laurence;
- Eller, Michael A.;
- Goonetilleke, Nilu;
- Thomas, Rasmi;
- Leviyang, Sivan;
- Harbolick, Elizabeth A.;
- Bose, Meera;
- Pham, Phuc;
- Oropeza, Celina;
- Poltavee, Kultida;
- O’Sullivan, Anne Marie;
- Billings, Erik;
- Merbah, Melanie;
- Costanzo, Margaret C.;
- Warren, Joanna A.;
- Slike, Bonnie;
- Li, Hui;
- Peachman, Kristina K.
Publication type:
Correction Notice
Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.
Published in:
PLoS Pathogens, 2017, v. 13, n. 7, p. 1, doi. 10.1371/journal.ppat.1006510
By:
- Kijak, Gustavo H.;
- Sanders-Buell, Eric;
- Chenine, Agnes-Laurence;
- Eller, Michael A.;
- Goonetilleke, Nilu;
- Thomas, Rasmi;
- Leviyang, Sivan;
- Harbolick, Elizabeth A.;
- Bose, Meera;
- Pham, Phuc;
- Oropeza, Celina;
- Poltavee, Kultida;
- O’Sullivan, Anne Marie;
- Billings, Erik;
- Merbah, Melanie;
- Costanzo, Margaret C.;
- Warren, Joanna A.;
- Slike, Bonnie;
- Li, Hui;
- Peachman, Kristina K.
Publication type:
Article
ANTIRETROVIRAL THERAPY REPAIRS CD4 T CELL DYSREGULATION IN PEOPLE LIVING WITH HIV.
Published in:
Topics in Antiviral Medicine, 2023, v. 31, n. 2, p. 161
By:
- Sponaugle, Alexis;
- Weideman, Ann Marie;
- Ranek, Jolene;
- Atassi, Gatphan;
- Kuritzkes, Daniel;
- Andrade, Adriana;
- Adimora, Adaora;
- Archin, Nancie;
- Margolis, David;
- Gay, Cynthia;
- Vincent, Benjamin;
- Stanley, Natalie;
- Hudgens, Michael;
- Eron, Joseph J.;
- Goonetilleke, Nilu
Publication type:
Article
Cohort Profile: The Flu Watch Study.
Published in:
2017
By:
- Fragaszy, Ellen B.;
- Warren-Gash, Charlotte;
- Lili Wang;
- Copas, Andrew;
- Dukes, Oliver;
- Edmunds, W. John;
- Goonetilleke, Nilu;
- Harvey, Gabrielle;
- Johnson, Anne M.;
- Kovar, Jana;
- C. Lim, Megan S.;
- McMichael, Andrew;
- Millett, Elizabeth R. C.;
- Nazareth, Irwin;
- Nguyen-Van-Tam, Jonathan S.;
- Tabassum, Faiza;
- Watson, John M.;
- Fatima Wurie;
- Zambon, Maria;
- Hayward, Andrew C.
Publication type:
journal article
Anti‐chlamydia IgG and IgA are insufficient to prevent endometrial chlamydia infection in women, and increased anti‐chlamydia IgG is associated with enhanced risk for incident infection.
Published in:
American Journal of Reproductive Immunology, 2019, v. 81, n. 5, p. N.PAG, doi. 10.1111/aji.13103
By:
- Darville, Toni;
- Albritton, Hannah L.;
- Zhong, Wujuan;
- Dong, Li;
- O'Connell, Catherine M.;
- Poston, Taylor B.;
- Quayle, Alison J.;
- Goonetilleke, Nilu;
- Wiesenfeld, Harold C.;
- Hillier, Sharon L.;
- Zheng, Xiaojing
Publication type:
Article
The Effects of Human Immunodeficiency Virus Type 1 (HIV-1) Antigen-Expanded Specific T-Cell Therapy and Vorinostat on Persistent HIV-1 Infection in People With HIV on Antiretroviral Therapy.
Published in:
Journal of Infectious Diseases, 2024, v. 229, n. 3, p. 743, doi. 10.1093/infdis/jiad423
By:
- Gay, Cynthia L;
- Hanley, Patrick J;
- Falcinelli, Shane D;
- Kuruc, JoAnn D;
- Pedersen, Susan M;
- Kirchherr, Jennifer;
- Raines, Samuel L M;
- Motta, Cecilia M;
- Lazarski, Chris;
- Chansky, Pamela;
- Tanna, Jay;
- Shibli, Abeer;
- Datar, Anushree;
- McCann, Chase D;
- Sili, Uluhan;
- Ke, Ruian;
- Eron, Joseph J;
- Archin, Nancie;
- Goonetilleke, Nilu;
- Bollard, Catherine M
Publication type:
Article
Reduced Endometrial Ascension and Enhanced Reinfection Associated With Immunoglobulin G Antibodies to Specific Chlamydia trachomatis Proteins in Women at Risk for Chlamydia.
Published in:
2022
By:
- Liu, Chuwen;
- Hufnagel, Katrin;
- O'Connell, Catherine M;
- Goonetilleke, Nilu;
- Mokashi, Neha;
- Waterboer, Tim;
- Tollison, Tammy S;
- Peng, Xinxia;
- Wiesenfeld, Harold C;
- Hillier, Sharon L;
- Zheng, Xiaojing;
- Darville, Toni
Publication type:
journal article
Increased detection of proliferating, polyfunctional, HIV-1-specific T cells in DNA-modified vaccinia virus Ankara-vaccinated human volunteers by cultured IFN-γ ELISPOT assay.
Published in:
European Journal of Immunology, 2009, v. 39, n. 4, p. 975, doi. 10.1002/eji.200839167
By:
- Winstone, Nicola;
- Guimarães-Walker, Ana;
- Roberts, Joanna;
- Brown, Denise;
- Loach, Vanessa;
- Goonetilleke, Nilu;
- Hanke, Tomáš;
- McMichael, Andrew J.
Publication type:
Article
Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation.
Published in:
Retrovirology, 2014, v. 11, n. 1, p. 101, doi. 10.1186/s12977-014-0101-0
By:
- Donglai Liu;
- Tao Zuo;
- Hora, Bhavna;
- Song, Hongshuo;
- Wei Kong;
- Xianghui Yu;
- Goonetilleke, Nilu;
- Bhattacharya, Tanmoy;
- Perelson, Alan S;
- Haynes, Barton F;
- McMichael, Andrew J;
- Feng Gao
Publication type:
Article
Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection.
Published in:
Retrovirology, 2014, v. 11, n. 1, p. 2, doi. 10.1186/s12977-014-0069-9
By:
- Ritchie, Adam John;
- Fangping Cai;
- Smith, Nicola M. G.;
- Sheri Chen;
- Hongshuo Song;
- Brackenridge, Simon;
- Abdool Karim, Salim S.;
- Korber, Bette T.;
- McMichael, Andrew J.;
- Feng Gao;
- Goonetilleke, Nilu
Publication type:
Article
Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/ founder genome.
Published in:
Retrovirology, 2012, v. 9, n. 1, p. 89, doi. 10.1186/1742-4690-9-89
By:
- Hongshuo Song;
- Pavlicek, Jeffrey W.;
- Fangping Cai;
- Tanmoy Bhattacharya;
- Hui Li;
- Iyer, Shilpa S.;
- Bar, Katharine J.;
- Decker, Julie M.;
- Goonetilleke, Nilu;
- Liu, Michael K. P.;
- Berg, Anna;
- Hora, Bhavna;
- Drinker, Mark S.;
- Eudailey, Josh;
- Pickeral, Joy;
- Moody, M. Anthony;
- Ferrari, Guido;
- McMichael, Andrew;
- Perelson, Alan S.;
- Shaw, George M.
Publication type:
Article

Found: 39

Sequence Analysis of Inducible, Replication-Competent Virus Reveals No Evidence of HIV-1 Evolution During Suppressive Antiviral Therapy, Indicating a Lack of Ongoing Viral Replication.

Improved detection of latent Mycobacterium tuberculosis infection in HIV-1 seropositive individuals using cultured cellular assays.

The HIV-1 latent reservoir is largely sensitive to circulating T cells.

Harnessing CD8<sup>+</sup> T Cells Under HIV Antiretroviral Therapy.

Reversion and T Cell Escape Mutations Compensate the Fitness Loss of a CD8<sup>+</sup> T Cell Escape Mutant in Their Cognate Transmitted/Founder Virus.

Comparison of Sexual Behavior and HIV Risk between Two HIV-1 Serodiscordant Couple Cohorts: The CHAVI 002 Stu.

The Magnitude and Kinetics of the Mucosal HIV-Specific CD8+ T Lymphocyte Response and Virus RNA Load in Breast Milk.

Natural T Cell-mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study.

Natural T Cell-mediated Protection against Seasonal and Pandemic Influenza.

Blocking Formation of the Stable HIV Reservoir: A New Perspective for HIV-1 Cure.

OMIP‐087: Thirty‐two parameter mass cytometry panel to assess human CD4 and CD8 T cell activation, memory subsets, and helper subsets.

A Reproducible, Objective Method Using MitoTracker® Fluorescent Dyes to Assess Mitochondrial Mass in T Cells by Flow Cytometry.

The immune response during acute HIV-1 infection: clues for vaccine development.

Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.

Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection.

A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies.

Interval dosing with the HDAC inhibitor vorinostat effectively reverses HIV latency.

Reliable Estimation of CD8 T Cell Inhibition of In Vitro HIV-1 Replication.

CD3 downregulation identifies high-avidity human CD8 T cells.

Relative rate and location of intra-host HIV evolution to evade cellular immunity are predictable.

The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation.

Proof-of-Principle for Immune Control of Global HIV-1 Reactivation In Vivo.

Cellular immune responses induced in cattle by heterologous prime–boost vaccination using recombinant viruses and bacille Calmette–Guérin.

Vaccines: Underlying Principles of Design and Testing.

Temporal Dynamics of CD8<sup>+</sup> T Cell Effector Responses during Primary HIV Infection.

Identification of Effective Subdominant Anti-HIV-1 CD8+ T Cells Within Entire Post-infection and Post-vaccination Immune Responses.

Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection.

Sequential CCR5-Tropic HIV-1 Reactivation from Distinct Cellular Reservoirs following Perturbation of Elite Control.

Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.

Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.

ANTIRETROVIRAL THERAPY REPAIRS CD4 T CELL DYSREGULATION IN PEOPLE LIVING WITH HIV.

Cohort Profile: The Flu Watch Study.

Anti‐chlamydia IgG and IgA are insufficient to prevent endometrial chlamydia infection in women, and increased anti‐chlamydia IgG is associated with enhanced risk for incident infection.

The Effects of Human Immunodeficiency Virus Type 1 (HIV-1) Antigen-Expanded Specific T-Cell Therapy and Vorinostat on Persistent HIV-1 Infection in People With HIV on Antiretroviral Therapy.

Reduced Endometrial Ascension and Enhanced Reinfection Associated With Immunoglobulin G Antibodies to Specific Chlamydia trachomatis Proteins in Women at Risk for Chlamydia.

Increased detection of proliferating, polyfunctional, HIV-1-specific T cells in DNA-modified vaccinia virus Ankara-vaccinated human volunteers by cultured IFN-γ ELISPOT assay.

Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation.

Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection.

Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/ founder genome.