Works by Goodman, Simon L.

Results: 30

Mouse polymorphonuclear granulocyte binding to extracellular matrix molecules involves β1 integrins.

Published in:

European Journal of Immunology, 1996, v. 26, n. 12, p. 3127, doi. 10.1002/eji.1830261245

By:

Frieser, Michael;
Hallmann, Rupert;
Johansson, Staffan;
Vestweber, Dietmar;
Goodman, Simon L.;
Sorokin, Lydia

Publication type:

Article

Structural basis for pure antagonism of integrin αVβ3 by a high-affinity form of fibronectin.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 383, doi. 10.1038/nsmb.2797

By:

Van Agthoven, Johannes F;
Xiong, Jian-Ping;
Alonso, José Luis;
Rui, Xianliang;
Adair, Brian D;
Goodman, Simon L;
Arnaout, M Amin

Publication type:

Article

Verbesserte Implantatmaterialien durch die Beschichtung mit hochspezifischen, nichtpeptidischen IntegrinligandenDiese Arbeit wurde von der DFG (SFB 563) und vom Bundesministerium für Bildung und Forschung (03N4012) unterstützt.

Published in:

Angewandte Chemie, 2004, v. 116, n. 48, p. 6818, doi. 10.1002/ange.200460770

By:

Claudia Dahmen;
Jörg Auernheimer;
Axel Meyer;
Anja Enderle;
Simon L. Goodman;
Horst Kessler

Publication type:

Article

Titanium Implant Materials with Improved Biocompatibility through Coating with Phosphonate-Anchored Cyclic RGD Peptides.

Published in:

ChemBioChem, 2005, v. 6, n. 11, p. 2034, doi. 10.1002/cbic.200500031

By:

Jörg Auernheimer;
Daniel Zukowski;
Claudia Dahmen;
Martin Kantlehner;
Anja Enderle;
Simon L. Goodman;
Horst Kessler

Publication type:

Article

Surface Coating with Cyclic RGD Peptides Stimulates Osteoblast Adhesion and Proliferation as well as Bone Formation.

Published in:

ChemBioChem, 2000, v. 1, n. 2, p. 107, doi. 10.1002/1439-7633(20000818)1:2<107::AID-CBIC107>3.0.CO;2-4

By:

Kantlehner, Martin;
Schaffner, Patricia;
Finsinger, Dirk;
Meyer, Jörg;
Jonczyk, Alfred;
Diefenbach, Beate;
Nies, Berthold;
Hölzemann, Günter;
Goodman, Simon L.;
Kessler, Horst

Publication type:

Article

Monitoring multiple angiogenesis-related molecules in the blood of cancer patients shows a correlation between VEGF-A and MMP-9 levels before treatment and divergent changes after surgical vs. conservative therapy.

Published in:

International Journal of Cancer, 2006, v. 118, n. 3, p. 755, doi. 10.1002/ijc.21408

By:

Zaman, Khalil;
Driscoll, Robert;
Hahn, Diane;
Werffeli, Patricia;
Goodman, Simon L.;
Bauer, Jean;
Leyvraz, Serge;
Lejeune, Ferdy;
Stupp, Roger;
Rüegg, Curzio

Publication type:

Article

Invasion patterns in brain metastases of solid cancers.

Published in:

Neuro-Oncology, 2013, v. 15, n. 12, p. 1664, doi. 10.1093/neuonc/not112

By:

Berghoff, Anna S.;
Rajky, Orsolya;
Winkler, Frank;
Bartsch, Rupert;
Furtner, Julia;
Hainfellner, Johannes A.;
Goodman, Simon L.;
Weller, Michael;
Schittenhelm, Jens;
Preusser, Matthias

Publication type:

Article

Integrins as Therapeutic Targets: Successes and Cancers.

Published in:

Cancers, 2017, v. 9, n. 9, p. 110, doi. 10.3390/cancers9090110

By:

Raab-Westphal, Sabine;
Marshall, John F.;
Goodman, Simon L.

Publication type:

Article

Polymerase chain reaction and focal contact formation indicate integrin expression in mesangial cells.

Published in:

Kidney International, 1993, v. 44, n. 5, p. 997, doi. 10.1038/ki.1993.341

By:

Petermann, Arndt;
Fees, Hans;
Grenz, Harald;
Goodman, Simon L.;
Sterzel, R. Bernd

Publication type:

Article

α6β1 Integrin and laminin E8: An increasingly complex simple story.

Published in:

Kidney International, 1992, v. 41, n. 3, p. 650, doi. 10.1038/ki.1992.100

By:

Goodman, Simon L.

Publication type:

Article

Integrin control of the transforming growth factor-[beta] pathway in glioblastoma.

Published in:

2013

By:

Roth, Patrick;
Silginer, Manuela;
Goodman, Simon L;
Hasenbach, Kathy;
Thies, Svenja;
Maurer, Gabriele;
Schraml, Peter;
Tabatabai, Ghazaleh;
Moch, Holger;
Tritschler, Isabel;
Weller, Michael

Publication type:

Journal Article

Integrin control of the transforming growth factor-β pathway in glioblastoma.

Published in:

Brain: A Journal of Neurology, 2013, v. 136, n. 2, p. 564, doi. 10.1093/brain/aws351

By:

Roth, Patrick;
Silginer, Manuela;
Goodman, Simon L.;
Hasenbach, Kathy;
Thies, Svenja;
Maurer, Gabriele;
Schraml, Peter;
Tabatabai, Ghazaleh;
Moch, Holger;
Tritschler, Isabel;
Weller, Michael

Publication type:

Article

Multimeric Cyclic RGD Peptides as Potential Tools for Tumor Targeting: Solid-Phase Peptide Synthesis and Chemoselective Oxime Ligation.

Published in:

Chemistry - A European Journal, 2003, v. 9, n. 12, p. 2717, doi. 10.1002/chem.200204304

By:

Georgette Thumshirn;
Ulrich Hersel;
Simon L. Goodman;
Horst Kessler

Publication type:

Article

Synthesis and Biological Evaluation of Integrin Antagonists Containing trans- and cis-2,5-Disubstituted THF Rings.

Published in:

Chemistry - A European Journal, 2000, v. 6, n. 4, p. 666, doi. 10.1002/(SICI)1521-3765(20000218)6:4<666::AID-CHEM666>3.0.CO;2-Z

By:

Osterkamp, Frank;
Ziemer, Burkhard;
Koert, Ulrich;
Wiesner, Matthias;
Raddatz, Peter;
Goodman, Simon L.

Publication type:

Article

The Antibody Society's antibody validation webinar series.

Published in:

mAbs (1942-0862), 2020, v. 12, n. 1, p. 1, doi. 10.1080/19420862.2020.1794421

By:

Voskuil, Jan L.A.;
Bandrowski, Anita;
Begley, C. Glenn;
Bradbury, Andrew R.M.;
Chalmers, Andrew D.;
Gomes, Aldrin V.;
Hardcastle, Travis;
Lund-Johansen, Fridtjof;
Plückthun, Andreas;
Roncador, Giovanna;
Solache, Alejandra;
Taussig, Michael J.;
Trimmer, James S.;
Williams, Cecilia;
Goodman, Simon L.

Publication type:

Article

Glycosylated RGD-Containing Peptides: Tracer for Tumor Targeting and Angiogenesis Imaging with Improved Biokinetics.

Published in:

Journal of Nuclear Medicine, 2001, v. 42, n. 2, p. 326

By:

Haubner, Roland;
Wester, Hans-Jürgen;
Burkhart, Fred;
Senekowitsch-Schmidtke, Reingard;
Weber, Wolfgang;
Goodman, Simon L.;
Kessler, Horst;
Schwaiger, Markus

Publication type:

Article

Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment.

Published in:

Journal of Cell Biology, 2009, v. 186, n. 4, p. 589, doi. 10.1083/jcb.200905085

By:

Xiong, Jian-Ping;
Mahalingham, Bhuvaneshwari;
Alonso, Jose Luis;
Borrelli, Laura Ann;
Rui, Xianliang;
Anand, Saurabh;
Hyman, Bradley T.;
Rysiok, Thomas;
Müller-Pompalla, Dirk;
Goodman, Simon L.;
Arnaout, M. Amin

Publication type:

Article

Three-dimensional EM structure of the ectodomain of integrin αV&beta3 in a complex with fibronectin.

Published in:

Journal of Cell Biology, 2005, v. 168, n. 7, p. 1109, doi. 10.1083/jcb.200410068

By:

Adair, Brian D.;
Xiong, Jian-Ping;
Maddock, Catherine;
Goodman, Simon L.;
Arnaout, M. Amin;
Yeager, Mark

Publication type:

Article

Erratum: Immunohistochemical analysis of integrin αvβ3 expression on tumor-associated vessels of human carcinomas. Int. J. Cancer, 71, 320-324 (1997).

Published in:

International Journal of Cancer, 1997, v. 72, n. 4, p. 706, doi. 10.1002/(SICI)1097-0215(19970807)72:4<706::AID-IJC25>3.0.CO;2-7

By:

Max, Regina;
Gerritsen, Roland R.C.M.;
Nooijen, Peet T.G.A.;
Goodman, Simon L.;
Sutter, Arne;
Keilholz, U.;
Ruiter, Dirk J.;
De Waal, Robert M.W.

Publication type:

Article

Immunohistochemical analysis of integrin αvβ3 expression on tumor-associated vessels of human carcinomas.

Published in:

International Journal of Cancer, 1997, v. 71, n. 3, p. 320, doi. 10.1002/(SICI)1097-0215(19970502)71:3<320::AID-IJC2>3.0.CO;2-#

By:

Max, Regina;
Gerritsen, Roland R.C.M.;
Nooijen, Peet T.G.A.;
Goodman, Simon L.;
Sutter, Arne;
Keilholz, Ulrich;
Ruiter, Dirk J.;
De Waal, Robert M.W.

Publication type:

Article

Designed Beta-Turn Mimic Based on the Allylic-Strain Concept: Evaluation of Structural and Biological Features by Incorporation into a Cyclic RGD Peptide (Cyclo(- L-arginylglycyl- L- α-aspartyl-)).

Published in:

Helvetica Chimica Acta, 2002, v. 85, n. 12, p. 4442, doi. 10.1002/hlca.200290021

By:

Sukopp, Martin;
Marinelli, Luciana;
Heller, Markus;
Brandl, Trixi;
Goodman, Simon L.;
Hoffmann, Reinhard W.;
Kessler, Horst

Publication type:

Article

Synthesis of Unnatural Lipohilic N-(9 H-Fluoren-9-ylmethoxy)carbonyl-Substituted α-Amino Acids and Their Incorporation into Cyclic RGD-Peptides: A structure-activity study.

Published in:

Helvetica Chimica Acta, 1997, v. 80, n. 4, p. 1280, doi. 10.1002/hlca.19970800423

By:

Koppitz, Marcus;
Huenges, Martin;
Gratias, Rainer;
Kessler, Horst;
Goodman, Simon L.;
Jonczyk, Alfred

Publication type:

Article

Piltdown wasn't cricket but does the hobbit ring true?

Published in:

2006

By:

Goodman, Simon L.

Publication type:

Letter

αv-Integrin isoform expression in primary human tumors and brain metastases.

Published in:

International Journal of Cancer, 2013, v. 133, n. 10, p. 2362, doi. 10.1002/ijc.28267

By:

Vogetseder, Alexander;
Thies, Svenja;
Ingold, Barbara;
Roth, Patrick;
Weller, Michael;
Schraml, Peter;
Goodman, Simon L.;
Moch, Holger

Publication type:

Article

The αVβ3/αVβ5 integrin inhibitor cilengitide augments tumor response to melphalan isolated limb perfusion in a sarcoma model.

Published in:

International Journal of Cancer, 2013, v. 132, n. 11, p. 2694, doi. 10.1002/ijc.27940

By:

ten Hagen, Timo L.M.;
Seynhaeve, Ann L.B.;
de Wiel‐Ambagtsheer, Gisela aan;
de Bruijn, Ernst A.;
van Tiel, Sandra T.;
Ruegg, Curzio;
Meyring, Michael;
Grell, Matthias;
Goodman, Simon L.;
Eggermont, Alexander M.M.

Publication type:

Article

Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE-MRI in a longitudinal in vivo study.

Published in:

International Journal of Cancer, 2011, v. 128, n. 10, p. 2453, doi. 10.1002/ijc.25563

By:

Bäuerle, Tobias;
Komljenovic, Dorde;
Merz, Maximilian;
Berger, Martin R.;
Goodman, Simon L.;
Semmler, Wolfhard

Publication type:

Article

Radiation sensitization of glioblastoma by cilengitide has unanticipated schedule-dependency.

Published in:

International Journal of Cancer, 2009, v. 124, n. 11, p. 2719, doi. 10.1002/ijc.24240

By:

Mikkelsen, Tom;
Brodie, Chaya;
Finniss, Susan;
Berens, Michael E.;
Rennert, Jessica L.;
Nelson, Kevin;
Lemke, Nancy;
Brown, Stephen L.;
Hahn, Diane;
Neuteboom, Berend;
Goodman, Simon L.

Publication type:

Article

Improving Implant Materials by Coating with Nonpeptidic, Highly Specific Integrin LigandsThis work was supported by the DFG, Sonderforschungsbereich 563, and by the German Federal Ministry of Education and Research under No. 03N4012.

Published in:

Angewandte Chemie International Edition, 2004, v. 43, n. 48, p. 6649, doi. 10.1002/anie.200460770

By:

Claudia Dahmen;
Jörg Auernheimer;
Axel Meyer;
Anja Enderle;
Simon L. Goodman;
Horst Kessler

Publication type:

Article

Nonpeptidic α.

Published in:

Angewandte Chemie International Edition, 2001, v. 40, n. 1, p. 165, doi. 10.1002/1521-3773(20010105)40:1<165::AID-ANIE165>3.0.CO;2-8

By:

Gibson, Christoph;
Sulyok, Gábor A. G.;
Hahn, Diane;
Goodman, Simon L.;
Hölzemann, Günter;
Kessler, Horst

Publication type:

Article

Carbohydrate Derivatives for Use in Drug Design: Cyclic αv-Selective RGD Peptides.

Published in:

Angewandte Chemie International Edition, 2000, v. 39, n. 15, p. 2761, doi. 10.1002/1521-3773(20000804)39:15<2761::AID-ANIE2761>3.0.CO;2-9

By:

Lohof, Elisabeth;
Planker, Eckart;
Mang, Christian;
Burkhart, Fred;
Dechantsreiter, Michael A.;
Haubner, Roland;
Wester, Hans-Jürgen;
Schwaiger, Markus;
Hölzemann, Günther;
Goodman, Simon L.;
Kessler, Horst

Publication type:

Article

Works by Goodman, Simon L.

Mouse polymorphonuclear granulocyte binding to extracellular matrix molecules involves β1 integrins.

Structural basis for pure antagonism of integrin α<sub>V</sub>β<sub>3</sub> by a high-affinity form of fibronectin.

Verbesserte Implantatmaterialien durch die Beschichtung mit hochspezifischen, nichtpeptidischen IntegrinligandenDiese Arbeit wurde von der DFG (SFB 563) und vom Bundesministerium für Bildung und Forschung (03N4012) unterstützt.

Titanium Implant Materials with Improved Biocompatibility through Coating with Phosphonate-Anchored Cyclic RGD Peptides.

Surface Coating with Cyclic RGD Peptides Stimulates Osteoblast Adhesion and Proliferation as well as Bone Formation.

Monitoring multiple angiogenesis-related molecules in the blood of cancer patients shows a correlation between VEGF-A and MMP-9 levels before treatment and divergent changes after surgical vs. conservative therapy.

Invasion patterns in brain metastases of solid cancers.

Integrins as Therapeutic Targets: Successes and Cancers.

Polymerase chain reaction and focal contact formation indicate integrin expression in mesangial cells.

α6β1 Integrin and laminin E8: An increasingly complex simple story.

Integrin control of the transforming growth factor-[beta] pathway in glioblastoma.

Integrin control of the transforming growth factor-β pathway in glioblastoma.

Multimeric Cyclic RGD Peptides as Potential Tools for Tumor Targeting: Solid-Phase Peptide Synthesis and Chemoselective Oxime Ligation.

Synthesis and Biological Evaluation of Integrin Antagonists Containing trans- and cis-2,5-Disubstituted THF Rings.

The Antibody Society's antibody validation webinar series.

Glycosylated RGD-Containing Peptides: Tracer for Tumor Targeting and Angiogenesis Imaging with Improved Biokinetics.

Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment.

Three-dimensional EM structure of the ectodomain of integrin αV&beta3 in a complex with fibronectin.

Erratum: Immunohistochemical analysis of integrin αvβ3 expression on tumor-associated vessels of human carcinomas. Int. J. Cancer, 71, 320-324 (1997).

Immunohistochemical analysis of integrin αvβ3 expression on tumor-associated vessels of human carcinomas.

Designed Beta-Turn Mimic Based on the Allylic-Strain Concept: Evaluation of Structural and Biological Features by Incorporation into a Cyclic RGD Peptide (Cyclo(- L-arginylglycyl- L- α-aspartyl-)).

Synthesis of Unnatural Lipohilic N-(9 H-Fluoren-9-ylmethoxy)carbonyl-Substituted α-Amino Acids and Their Incorporation into Cyclic RGD-Peptides: A structure-activity study.

Piltdown wasn't cricket but does the hobbit ring true?

αv-Integrin isoform expression in primary human tumors and brain metastases.

The αVβ3/αVβ5 integrin inhibitor cilengitide augments tumor response to melphalan isolated limb perfusion in a sarcoma model.

Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE-MRI in a longitudinal in vivo study.

Radiation sensitization of glioblastoma by cilengitide has unanticipated schedule-dependency.

Improving Implant Materials by Coating with Nonpeptidic, Highly Specific Integrin LigandsThis work was supported by the DFG, Sonderforschungsbereich 563, and by the German Federal Ministry of Education and Research under No. 03N4012.

Nonpeptidic α.

Carbohydrate Derivatives for Use in Drug Design: Cyclic α<sub>v</sub>-Selective RGD Peptides.