Works matching AU Gontsarik, Mark


Results: 11
    1

    Thioamides Adjacent to the Ionizable Amine Headgroup in Ionizable Lipids Reduce the pK<sub>a</sub> of Lipid Nanoparticles and Enhance mRNA Transfection Efficiency in Vitro and in Vivo.

    Published in:
    Angewandte Chemie International Edition, 2025, v. 64, n. 28, p. 1, doi. 10.1002/anie.202506954
    By:
    • Chen, Yong;
    • De Lombaerde, Emily;
    • Bugler‐Lamb, Aimée;
    • Zhong, Zifu;
    • Schuijs, Martijn J.;
    • Gomez, Claudia M. Brenis;
    • De Baere, Jamie;
    • Gontsarik, Mark;
    • Lauwers, Heleen;
    • Deswarte, Kim;
    • Sanders, Niek N.;
    • Lambrecht, Bart N.;
    • Guilliams, Martin;
    • De Geest, Bruno G.
    Publication type:
    Article
    2

    Thioamides Adjacent to the Ionizable Amine Headgroup in Ionizable Lipids Reduce the pK<sub>a</sub> of Lipid Nanoparticles and Enhance mRNA Transfection Efficiency in Vitro and in Vivo.

    Published in:
    Angewandte Chemie, 2025, v. 137, n. 28, p. 1, doi. 10.1002/ange.202506954
    By:
    • Chen, Yong;
    • De Lombaerde, Emily;
    • Bugler‐Lamb, Aimée;
    • Zhong, Zifu;
    • Schuijs, Martijn J.;
    • Gomez, Claudia M. Brenis;
    • De Baere, Jamie;
    • Gontsarik, Mark;
    • Lauwers, Heleen;
    • Deswarte, Kim;
    • Sanders, Niek N.;
    • Lambrecht, Bart N.;
    • Guilliams, Martin;
    • De Geest, Bruno G.
    Publication type:
    Article
    3

    Intratumoral delivery of lipid nanoparticle-formulated mRNA encoding IL-21, IL-7, and 4-1BBL induces systemic anti-tumor immunity.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54877-9
    By:
    • Hamouda, Ahmed E. I.;
    • Filtjens, Jessica;
    • Brabants, Elisabeth;
    • Kancheva, Daliya;
    • Debraekeleer, Ayla;
    • Brughmans, Jan;
    • Jacobs, Lotte;
    • Bardet, Pauline M. R.;
    • Knetemann, Elisabeth;
    • Lefesvre, Pierre;
    • Allonsius, Lize;
    • Gontsarik, Mark;
    • Varela, Ismael;
    • Crabbé, Marian;
    • Clappaert, Emile J.;
    • Cappellesso, Federica;
    • Caro, Aarushi A.;
    • Gordún Peiró, Alícia;
    • Fredericq, Luna;
    • Hadadi, Eva
    Publication type:
    Article
    4
    5

    A Fentanyl Hapten‐Displaying Lipid Nanoparticle Vaccine that Non‐Covalently Encapsulates a TLR7/8 Agonist and T‐Helper Epitope Induces Protective Anti‐Fentanyl Immunity.

    Published in:
    Angewandte Chemie, 2025, v. 137, n. 7, p. 1, doi. 10.1002/ange.202419031
    By:
    • Zhong, Zifu;
    • Deventer, Marie H.;
    • Chen, Yong;
    • Vanhee, Stijn;
    • Lammens, Inés;
    • Deswarte, Kim;
    • Huang, Yi;
    • Ye, Tingting;
    • Wang, Haixiu;
    • Nuhn, Lutz;
    • Vandeputte, Marthe M.;
    • Gontsarik, Mark;
    • Cui, Xiaole;
    • Sanders, Niek N.;
    • Lienenklaus, Stefan;
    • N. Lambrecht, Bart;
    • Baptista, Antonio P.;
    • Stove, Christophe P.;
    • G. De Geest, Bruno
    Publication type:
    Article
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    11

    A Fentanyl Hapten‐Displaying Lipid Nanoparticle Vaccine that Non‐Covalently Encapsulates a TLR7/8 Agonist and T‐Helper Epitope Induces Protective Anti‐Fentanyl Immunity.

    Published in:
    Angewandte Chemie International Edition, 2025, v. 64, n. 7, p. 1, doi. 10.1002/anie.202419031
    By:
    • Zhong, Zifu;
    • Deventer, Marie H.;
    • Chen, Yong;
    • Vanhee, Stijn;
    • Lammens, Inés;
    • Deswarte, Kim;
    • Huang, Yi;
    • Ye, Tingting;
    • Wang, Haixiu;
    • Nuhn, Lutz;
    • Vandeputte, Marthe M.;
    • Gontsarik, Mark;
    • Cui, Xiaole;
    • Sanders, Niek N.;
    • Lienenklaus, Stefan;
    • N. Lambrecht, Bart;
    • Baptista, Antonio P.;
    • Stove, Christophe P.;
    • G. De Geest, Bruno
    Publication type:
    Article