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Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28108-y
By:
- Radke, Joshua B.;
- Melillo, Bruno;
- Mittal, Payal;
- Sharma, Manmohan;
- Sharma, Amit;
- Fu, Yong;
- Uddin, Taher;
- Gonse, Arthur;
- Comer, Eamon;
- Schreiber, Stuart L.;
- Gupta, Anil K.;
- Chatterjee, Arnab K.;
- Sibley, L. David
Publication type:
Article
Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase.
Published in:
Science Translational Medicine, 2020, v. 12, n. 563, p. 1, doi. 10.1126/scitranslmed.aba8412
By:
- Vinayak, Sumiti;
- Jumani, Rajiv S.;
- Miller, Peter;
- Hasan, Muhammad M.;
- McLeod, Briana I.;
- Tandel, Jayesh;
- Stebbins, Erin E.;
- Teixeira, Jose E.;
- Borrel, Julien;
- Gonse, Arthur;
- Zhang, Mingliang;
- Yu, Xianshui;
- Wernimont, Amy;
- Walpole, Chris;
- Eckley, Sean;
- Love, Melissa S.;
- McNamara, Case W.;
- Sharma, Manmohan;
- Sharma, Amit;
- Scherer, Christina A.
Publication type:
Article
Combining recombinase polymerase amplification and DNA‐templated reaction for SARS‐CoV‐2 sensing with dual fluorescence and lateral flow assay output.
Published in:
Biopolymers, 2022, v. 113, n. 4, p. 1, doi. 10.1002/bip.23485
By:
- Farrera‐Soler, Lluc;
- Gonse, Arthur;
- Kim, Ki Tae;
- Barluenga, Sofia;
- Winssinger, Nicolas
Publication type:
Article
Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20478-5
By:
- Sharma, Manmohan;
- Malhotra, Nipun;
- Yogavel, Manickam;
- Harlos, Karl;
- Melillo, Bruno;
- Comer, Eamon;
- Gonse, Arthur;
- Parvez, Suhel;
- Mitasev, Branko;
- Fang, Francis G.;
- Schreiber, Stuart L.;
- Sharma, Amit
Publication type:
Article

Found: 4

Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase.

Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase.

Combining recombinase polymerase amplification and DNA‐templated reaction for SARS‐CoV‐2 sensing with dual fluorescence and lateral flow assay output.

Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines.