Works by Gong-Ping Liu

Results: 36

Overexpression of TECPR1 improved cognitive function of P301S‐tau mice via activation of autophagy in the early and late process.

Published in:

Aging Cell, 2025, v. 24, n. 3, p. 1, doi. 10.1111/acel.14404

By:

Li, Ting;
Liu, Ruijuan;
He, Ye;
Zhang, Bingge;
Rui, Xuexiang;
Yang, Xifei;
Wang, Jian‐Zhi;
Zeng, Juan;
Li, Gang;
Li, Xiao;
Liu, Gong‐Ping

Publication type:

Article

Expression of 1N3R-Tau Isoform Inhibits Cell Proliferation by Inducing S Phase Arrest in N2a Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0119865

By:

Li, Li;
Xu, Zhi-Peng;
Liu, Gong-Ping;
Xu, Cheng;
Wang, Zhi-Hao;
Li, Xiao-Guang;
Liu, En-Jie;
Zeng, Juan;
Chai, Da-Min;
Yao, Wen-Long;
Wang, Jian-Zhi

Publication type:

Article

Magnesium Protects Cognitive Functions and Synaptic Plasticity in Streptozotocin-Induced Sporadic Alzheimer’s Model.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108645

By:

Xu, Zhi-Peng;
Li, Li;
Bao, Jian;
Wang, Zhi-Hao;
Zeng, Juan;
Liu, En-Jie;
Li, Xiao-Guang;
Huang, Rong-Xi;
Gao, Di;
Li, Meng-Zhu;
Zhang, Yao;
Liu, Gong-Ping;
Wang, Jian-Zhi

Publication type:

Article

Silencing I2PP2A rescues tau pathologies and memory deficits through rescuing PP2A and inhibiting GSK-3β signaling in human tau transgenic mice.

Published in:

Frontiers in Aging Neuroscience, 2014, v. 6, p. 1, doi. 10.3389/fnagi.2014.00123

By:

Yao Zhang;
Rong-Hong Ma;
Xia-Chun Li;
Jia-Yu Zhang;
Hai-Rong Shi;
Wei Wei;
Dan-Ju Luo;
Qun Wang;
Jian-Zhi Wang;
Gong-Ping Liu

Publication type:

Article

Silencing I2PP2A rescues tau pathologies and memory deficits through rescuing PP2A and inhibiting GSK-3β signaling in human tau transgenic mice.

Published in:

Frontiers in Aging Neuroscience, 2014, v. 6, p. 1, doi. 10.3389/fnagi.2014.00123

By:

Yao Zhang;
Rong-Hong Ma;
Xia-Chun Li;
Jia-Yu Zhang;
Hai-Rong Shi;
Wei Wei;
Dan-Ju Luo;
Qun Wang;
Jian-Zhi Wang;
Gong-Ping Liu

Publication type:

Article

Targeting tau in Alzheimer's disease: from mechanisms to clinical therapy.

Published in:

Neural Regeneration Research, 2024, v. 19, n. 7, p. 1489, doi. 10.4103/1673-5374.385847

By:

Jinwang Ye;
Huali Wan;
Sihua Chen;
Gong-Ping Liu

Publication type:

Article

Upregulation of ISG15 induced by MAPT/tau accumulation represses autophagic flux by inhibiting HDAC6 activity: a vicious cycle in Alzheimer disease.

Published in:

Autophagy, 2025, v. 21, n. 4, p. 807, doi. 10.1080/15548627.2024.2431472

By:

Liu, Qian;
Wang, Xin;
Fang, Zhi-Ting;
Zhao, Jun-Ning;
Rui, Xue-Xiang;
Zhang, Bing-Ge;
He, Ye;
Liu, Rui-Juan;
Chen, Jian;
Chai, Gao-Shang;
Liu, Gong-Ping

Publication type:

Article

MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.

Published in:

Autophagy, 2020, v. 16, n. 4, p. 641, doi. 10.1080/15548627.2019.1633862

By:

Feng, Qiong;
Luo, Yu;
Zhang, Xiang-Nan;
Yang, Xi-Fei;
Hong, Xiao-Yue;
Sun, Dong-Shen;
Li, Xia-Chun;
Hu, Yu;
Li, Xiao-Guang;
Zhang, Jun-Fei;
Li, Xiao;
Yang, Ying;
Wang, Qun;
Liu, Gong-Ping;
Wang, Jian-Zhi

Publication type:

Article

Human wild-type full-length tau accumulation disrupts mitochondrial dynamics and the functions via increasing mitofusins.

Published in:

Scientific Reports, 2016, p. 24756, doi. 10.1038/srep24756

By:

Li, Xia-Chun;
Hu, Yu;
Wang, Zhi-hao;
Luo, Yu;
Zhang, Yao;
Liu, Xiu-Ping;
Feng, Qiong;
Wang, Qun;
Ye, Keqiang;
Liu, Gong-Ping;
Wang, Jian-Zhi

Publication type:

Article

Spatial training preserves associative memory capacity with augmentation of dendrite ramification and spine generation in Tg2576 mice.

Published in:

Scientific Reports, 2015, p. 9488, doi. 10.1038/srep09488

By:

Jiang, Xia;
Chai, Gao-Shang;
Wang, Zhi-Hao;
Hu, Yu;
Li, Xiao-Guang;
Ma, Zhi-Wei;
Wang, Qun;
Wang, Jian-Zhi;
Liu, Gong-Ping

Publication type:

Article

Knockdown of pp32 Increases Histone Acetylation and Ameliorates Cognitive Deficits.

Published in:

Frontiers in Aging Neuroscience, 2017, v. 9, p. 1, doi. 10.3389/fnagi.2017.00104

By:

Qiong Feng;
Gao-Shang Chai;
Zhi-Hao Wang;
Yu Hu;
Dong-Sheng Sun;
Xiao-Guang Li;
Rong-Hong Ma;
Yi-Rong Li;
Dan Ke;
Jian-Zhi Wang;
Gong-Ping Liu

Publication type:

Article

Effects of tau phosphorylation on proteasome activity

Published in:

FEBS Letters, 2007, v. 581, n. 7, p. 1521, doi. 10.1016/j.febslet.2007.02.065

By:

Ren, Qing-Guo;
Liao, Xiao-Mei;
Chen, Xiao-Qian;
Liu, Gong-Ping;
Wang, Jian-Zhi

Publication type:

Article

δ-SECRETASE–CLEAVED TAU STIMULATES Aβ PRODUCTION VIA ACTIVATING STAT1-BACE1 PATHWAY IN ALZHEIMER’S DISEASE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1305, doi. 10.1016/j.jalz.2017.06.1992

By:

Ye, Keqiang;
Zhang, Zhentao;
Wang, Jian-Zhi;
Liu, Gong-ping;
Yu, Shan-Ping;
Li, Xiao-Guang

Publication type:

Article

Glycogen synthase kinase-3beta regulates tyrosine-307 phosphorylation of protein phosphatase-2A via protein tyrosine phosphatase 1B but not Src

Published in:

2011

By:

Liu, Gong-Ping

Publication type:

Abstract

Knockdown I2PP2A attenuates tau hyperphosphorylation and the underlying mechanisms

Published in:

2010

By:

Liu, Gong-ping;
Shi, Hai-rong;
Wei, Wei;
Yao, Xiu-qing;
Wang, Qun;
Wang, Jian-zhi

Publication type:

Abstract

Glycogen synthase kinase-3 negatively regulates the level of protein phosphatase-2A catalytic subunit through camp-responsive element-binding protein-dependent pathway

Published in:

2009

By:

Yang-Yang, Yin;
Xiao-Xue, Zhang;
Xiu-Qing, Yao;
Bin, Liu;
Gong-Ping, Liu;
Jian-Zhi, Wang

Publication type:

Abstract

Tau acetylates and stabilizes β‐catenin thereby promoting cell survival.

Published in:

EMBO Reports, 2020, v. 21, n. 3, p. 1, doi. 10.15252/embr.201948328

By:

Liu, Enjie;
Zhou, Qiuzhi;
Xie, Ao‐Ji;
Li, Xiaoguang;
Li, Mengzhu;
Ye, Jinwang;
Li, Shihong;
Ke, Dan;
Wang, Qun;
Xu, Zhi‐Peng;
Li, Li;
Yang, Ying;
Liu, Gong‐Ping;
Wang, Xiao‐Chuan;
Li, Hong‐Lian;
Wang, Jian‐Zhi

Publication type:

Article

Tau accumulation triggers STAT1‐dependent memory deficits by suppressing NMDA receptor expression.

Published in:

EMBO Reports, 2019, v. 20, n. 6, p. N.PAG, doi. 10.15252/embr.201847202

By:

Li, Xiao‐Guang;
Hong, Xiao‐Yue;
Wang, Ya‐li;
Zhang, Shu‐Juan;
Zhang, Jun‐Fei;
Li, Xia‐Chun;
Liu, Yan‐Chao;
Sun, Dong‐Shen;
Feng, Qiong;
Ye, Jin‐Wang;
Gao, Yuan;
Ke, Dan;
Wang, Qun;
Li, Hong‐lian;
Ye, Keqiang;
Liu, Gong‐Ping;
Wang, Jian‐Zhi

Publication type:

Article

Recombinant human erythropoietin ameliorates cognitive dysfunction of APP/PS1 mice by attenuating neuron apoptosis via HSP90β.

Published in:

2022

By:

Wan, Hua-Li;
Zhang, Bing-Ge;
Chen, Chongyang;
Liu, Qian;
Li, Ting;
He, Ye;
Xie, Yongmei;
Yang, Xifei;
Wang, Jian-Zhi;
Liu, Gong-Ping

Publication type:

Letter

Downregulating ANP32A rescues synapse and memory loss via chromatin remodeling in Alzheimer model.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0178-8

By:

Gao-Shang Chai;
Qiong Feng;
Zhi-Hao Wang;
Yu Hu;
Dong-Sheng Sun;
Xiao-Guang Li;
Dan Ke;
Hong-Lian Li;
Gong-Ping Liu;
Jian-Zhi Wang

Publication type:

Article

Long-term Ameliorative Effects of the Antidepressant Fluoxetine Exposure on Cognitive Deficits in 3 × TgAD Mice.

Published in:

Molecular Neurobiology, 2017, v. 54, n. 6, p. 4160, doi. 10.1007/s12035-016-9952-9

By:

Jin, Li;
Gao, Li-Feng;
Sun, Dong-Sheng;
Wu, Hao;
Wang, Qun;
Ke, Dan;
Lei, Hao;
Wang, Jian-Zhi;
Liu, Gong-Ping

Publication type:

Article

Silencing PP2A Inhibitor by Lenti-shRNA Interference Ameliorates Neuropathologies and Memory Deficits in tg2576 Mice.

Published in:

Molecular Therapy, 2013, v. 21, n. 12, p. 2247, doi. 10.1038/mt.2013.189

By:

Liu, Gong-Ping;
Wei, Wei;
Zhou, Xin;
Shi, Hai-Rong;
Liu, Xing-Hua;
Chai, Gao-Shang;
Yao, Xiu-Qing;
Zhang, Jia-Yu;
Peng, Cai-Xia;
Hu, Juan;
Li, Xia-Chun;
Wang, Qun;
Wang, Jian-Zhi

Publication type:

Article

Glycogen synthase kinase-3β regulates leucine-309 demethylation of protein phosphatase-2A via PPMT1 and PME-1

Published in:

FEBS Letters, 2012, v. 586, n. 16, p. 2522, doi. 10.1016/j.febslet.2012.06.018

By:

Yao, Xiu-Qing;
Li, Xia-Chun;
Zhang, Xiao-Xue;
Yin, Yang-Yang;
Liu, Bin;
Luo, Dan-Ju;
Wang, Qun;
Wang, Jian-Zhi;
Liu, Gong-Ping

Publication type:

Article

Knockdown of phosphotyrosyl phosphatase activator induces apoptosis via mitochondrial pathway and the attenuation by simultaneous tau hyperphosphorylation.

Published in:

Journal of Neurochemistry, 2014, v. 130, n. 6, p. 816, doi. 10.1111/jnc.12761

By:

Luo, Dan‐Ju;
Feng, Qiong;
Wang, Zhi‐Hao;
Sun, Dong‐Sheng;
Wang, Qun;
Wang, Jian‐Zhi;
Liu, Gong‐Ping

Publication type:

Article

Betaine attenuates Alzheimer-like pathological changes and memory deficits induced by homocysteine.

Published in:

Journal of Neurochemistry, 2013, v. 124, n. 3, p. 388, doi. 10.1111/jnc.12094

By:

Chai, Gao‐Shang;
Jiang, Xia;
Ni, Zhong‐Fei;
Ma, Zhi‐Wei;
Xie, Ao‐Ji;
Cheng, Xiang‐Shu;
Wang, Qun;
Wang, Jian‐Zhi;
Liu, Gong‐Ping

Publication type:

Article

Acetylated tau exacerbates apoptosis by disturbing mitochondrial dynamics in HEK293 cells.

Published in:

Journal of Neurochemistry, 2024, v. 168, n. 3, p. 288, doi. 10.1111/jnc.16053

By:

Zhang, Jun‐Fei;
Fang, Zhi‐Ting;
Zhao, Jun‐Ning;
Liu, Gong‐Ping;
Shen, Xin;
Jiang, Gao‐Feng;
Liu, Qian

Publication type:

Article

Acetone–butanol–ethanol (ABE) fermentation using Clostridium acetobutylicum XY16 and in situ recovery by PDMS/ceramic composite membrane.

Published in:

Bioprocess & Biosystems Engineering, 2012, v. 35, n. 7, p. 1057, doi. 10.1007/s00449-012-0721-5

By:

Wu, Hao;
Chen, Xiao-Peng;
Liu, Gong-Ping;
Jiang, Min;
Guo, Ting;
Jin, Wan-Qin;
Wei, Ping;
Zhu, Da-Wei

Publication type:

Article

Applications of multi‐omics analysis in human diseases.

Published in:

MedComm, 2023, v. 4, n. 4, p. 1, doi. 10.1002/mco2.315

By:

Chen, Chongyang;
Wang, Jing;
Pan, Donghui;
Wang, Xinyu;
Xu, Yuping;
Yan, Junjie;
Wang, Lizhen;
Yang, Xifei;
Yang, Min;
Liu, Gong‐Ping

Publication type:

Article

Multiomics analysis of human peripheral blood reveals markedmolecular profiling changes caused by one night of sleep deprivation.

Published in:

MedComm, 2023, v. 4, n. 3, p. 1, doi. 10.1002/mco2.252

By:

Chongyang Chen;
Jing Wang;
Chao Yang;
Haitao Yu;
Bingge Zhang;
Xiao Yang;
Bocheng Xiong;
Yongmei Xie;
Shupeng Li;
Zaijun Zhang;
Feiqi Zhu;
Jianjun Liu;
Gong-Ping Liu;
Xifei Yang

Publication type:

Article

Folate/vitamin-B12 Prevents Chronic Hyperhomocysteinemia-Induced Tau Hyperphosphorylation and Memory Deficits in Aged Rats.

Published in:

Journal of Alzheimer's Disease, 2011, v. 27, n. 3, p. 639, doi. 10.3233/JAD-2011-110770

By:

Wei, Wei;
Liu, Ying-Hua;
Zhang, Chang-E.;
Wang, Qun;
Wei, Zelan;
Mousseau, Darrell D.;
Wang, Jian-Zhi;
Tian, Qing;
Liu, Gong-Ping

Publication type:

Article

STAT3 ameliorates cognitive deficits by positively regulating the expression of NMDARs in a mouse model of FTDP-17.

Published in:

Signal Transduction & Targeted Therapy, 2020, v. 5, n. 1, p. 1, doi. 10.1038/s41392-020-00290-9

By:

Hong, Xiao-Yue;
Wan, Hua-Li;
Li, Ting;
Zhang, Bing-Ge;
Li, Xiao-Guang;
Wang, Xin;
Li, Xiao;
Liu, Qian;
Chen, Chong-Yang;
Yang, Ying;
Wang, Qun;
Li, Shu-Peng;
Yu, Hao;
Wang, Jian-Zhi;
Yang, Xi-Fei;
Liu, Gong-Ping

Publication type:

Article

Melatonin ameliorates cognitive deficits through improving mitophagy in a mouse model of Alzheimer's disease.

Published in:

Journal of Pineal Research, 2021, v. 71, n. 4, p. 1, doi. 10.1111/jpi.12774

By:

Chen, Chongyang;
Yang, Chao;
Wang, Jing;
Huang, Xi;
Yu, Haitao;
Li, Shangming;
Li, Shupeng;
Zhang, Zaijun;
Liu, Jianjun;
Yang, Xifei;
Liu, Gong‐Ping

Publication type:

Article

Upregulation of astrocytes protein phosphatase-2A stimulates astrocytes migration via inhibiting p38 MAPK in tg2576 mice.

Published in:

Glia (0894-1491), 2012, v. 60, n. 9, p. 1279, doi. 10.1002/glia.22347

By:

Liu, Xiu-Ping;
Zheng, Hong-Yun;
Qu, Min;
Zhang, Yao;
Cao, Fu-Yuan;
Wang, Qun;
Ke, Dan;
Liu, Gong-Ping;
Wang, Jian-Zhi

Publication type:

Article

R13 preserves motor performance in SOD1G93A mice by improving mitochondrial function.

Published in:

Theranostics, 2021, v. 11, n. 15, p. 7294, doi. 10.7150/thno.56070

By:

Xiao Li;
Chongyang Chen;
Xu Zhan;
Binyao Li;
Zaijun Zhang;
Shupeng Li;
Yongmei Xie;
Xiangrong Song;
Yuanyuan Shen;
Jianjun Liu;
Ping Liu;
Gong-Ping Liu;
Xifei Yang

Publication type:

Article

STAT3 ameliorates cognitive deficits via regulation of NMDAR expression in an Alzheimer's disease animal model.

Published in:

Theranostics, 2021, v. 11, n. 11, p. 5511, doi. 10.7150/thno.56541

By:

Hua-Li Wan;
Xiao-Yue Hong;
Zai-Hua Zhao;
Ting Li;
Bing-Ge Zhang;
Qian Liu;
Qun Wang;
Shi Zhao;
Jian-Zhi Wang;
Xue-Feng Shen;
Gong-Ping Liu

Publication type:

Article

Repeated Restraint Stress Led to Cognitive Dysfunction by NMDA Receptor-Mediated Hippocampal CA3 Dendritic Spine Impairments in Juvenile Sprague-Dawley Rats.

Published in:

Frontiers in Molecular Neuroscience, 2020, v. 13, p. N.PAG, doi. 10.3389/fnmol.2020.552787

By:

Sun, Dong-sheng;
Zhong, Gang;
Cao, Hong-Xia;
Hu, Yu;
Hong, Xiao-Yue;
Li, Ting;
Li, Xiao;
Liu, Qian;
Wang, Qun;
Ke, Dan;
Liu, Gong-ping;
Ma, Rong-Hong;
Luo, Dan-Ju

Publication type:

Article

Works by Gong-Ping Liu

Overexpression of TECPR1 improved cognitive function of P301S‐tau mice via activation of autophagy in the early and late process.

Expression of 1N3R-Tau Isoform Inhibits Cell Proliferation by Inducing S Phase Arrest in N2a Cells.

Magnesium Protects Cognitive Functions and Synaptic Plasticity in Streptozotocin-Induced Sporadic Alzheimer’s Model.

Silencing I<sub>2</sub><sup>PP2A</sup> rescues tau pathologies and memory deficits through rescuing PP2A and inhibiting GSK-3β signaling in human tau transgenic mice.

Silencing I<sub>2</sub><sup>PP2A</sup> rescues tau pathologies and memory deficits through rescuing PP2A and inhibiting GSK-3β signaling in human tau transgenic mice.

Targeting tau in Alzheimer's disease: from mechanisms to clinical therapy.

Upregulation of ISG15 induced by MAPT/tau accumulation represses autophagic flux by inhibiting HDAC6 activity: a vicious cycle in Alzheimer disease.

MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.

Human wild-type full-length tau accumulation disrupts mitochondrial dynamics and the functions via increasing mitofusins.

Spatial training preserves associative memory capacity with augmentation of dendrite ramification and spine generation in Tg2576 mice.

Knockdown of pp32 Increases Histone Acetylation and Ameliorates Cognitive Deficits.

Effects of tau phosphorylation on proteasome activity

δ-SECRETASE–CLEAVED TAU STIMULATES Aβ PRODUCTION VIA ACTIVATING STAT1-BACE1 PATHWAY IN ALZHEIMER’S DISEASE.

Glycogen synthase kinase-3beta regulates tyrosine-307 phosphorylation of protein phosphatase-2A via protein tyrosine phosphatase 1B but not Src

Knockdown I2PP2A attenuates tau hyperphosphorylation and the underlying mechanisms

Glycogen synthase kinase-3 negatively regulates the level of protein phosphatase-2A catalytic subunit through camp-responsive element-binding protein-dependent pathway

Tau acetylates and stabilizes β‐catenin thereby promoting cell survival.

Tau accumulation triggers STAT1‐dependent memory deficits by suppressing NMDA receptor expression.

Recombinant human erythropoietin ameliorates cognitive dysfunction of APP/PS1 mice by attenuating neuron apoptosis via HSP90β.

Downregulating ANP32A rescues synapse and memory loss via chromatin remodeling in Alzheimer model.

Long-term Ameliorative Effects of the Antidepressant Fluoxetine Exposure on Cognitive Deficits in 3 × TgAD Mice.

Silencing PP2A Inhibitor by Lenti-shRNA Interference Ameliorates Neuropathologies and Memory Deficits in tg2576 Mice.

Glycogen synthase kinase-3β regulates leucine-309 demethylation of protein phosphatase-2A via PPMT1 and PME-1

Knockdown of phosphotyrosyl phosphatase activator induces apoptosis via mitochondrial pathway and the attenuation by simultaneous tau hyperphosphorylation.

Betaine attenuates Alzheimer-like pathological changes and memory deficits induced by homocysteine.

Acetylated tau exacerbates apoptosis by disturbing mitochondrial dynamics in HEK293 cells.

Acetone–butanol–ethanol (ABE) fermentation using Clostridium acetobutylicum XY16 and in situ recovery by PDMS/ceramic composite membrane.

Applications of multi‐omics analysis in human diseases.

Multiomics analysis of human peripheral blood reveals markedmolecular profiling changes caused by one night of sleep deprivation.

Folate/vitamin-B12 Prevents Chronic Hyperhomocysteinemia-Induced Tau Hyperphosphorylation and Memory Deficits in Aged Rats.

STAT3 ameliorates cognitive deficits by positively regulating the expression of NMDARs in a mouse model of FTDP-17.

Melatonin ameliorates cognitive deficits through improving mitophagy in a mouse model of Alzheimer's disease.

Upregulation of astrocytes protein phosphatase-2A stimulates astrocytes migration via inhibiting p38 MAPK in tg2576 mice.

R13 preserves motor performance in SOD1<sup>G93A</sup> mice by improving mitochondrial function.

STAT3 ameliorates cognitive deficits via regulation of NMDAR expression in an Alzheimer's disease animal model.

Repeated Restraint Stress Led to Cognitive Dysfunction by NMDA Receptor-Mediated Hippocampal CA3 Dendritic Spine Impairments in Juvenile Sprague-Dawley Rats.