Works by Gonçalves, Nélio

Results: 19

Caffeine alleviates progressive motor deficits in a transgenic mouse model of spinocerebellar ataxia.

Published in:

2017

By:

Gonçalves, Nélio;
Simões, Ana T.;
Prediger, Rui D.;
Hirai, Hirokazu;
Cunha, Rodrigo A.;
Pereira de Almeida, Luís;
Gonçalves, Nélio;
Simões, Ana T;
Pereira de Almeida, Luís

Publication type:

journal article

Nucleolin Overexpression Predicts Patient Prognosis While Providing a Framework for Targeted Therapeutic Intervention in Lung Cancer.

Published in:

Cancers, 2022, v. 14, n. 9, p. N.PAG, doi. 10.3390/cancers14092217

By:

Valério-Fernandes, Ângela;
Fonseca, Nuno A.;
Gonçalves, Nélio;
Cruz, Ana F.;
Pereira, Marta I.;
Gregório, Ana C.;
Moura, Vera;
Ladeirinha, Ana F.;
Alarcão, Ana;
Gonçalves, Joana;
Abrunhosa, Antero;
Melo, Joana B.;
Carvalho, Lina;
Simões, Sérgio;
Moreira, João N.

Publication type:

Article

The Enhanced Efficacy of Intracellular Delivery of Doxorubicin/C6-Ceramide Combination Mediated by the F3 Peptide/Nucleolin System Is Supported by the Downregulation of the PI3K/Akt Pathway.

Published in:

Cancers, 2021, v. 13, n. 12, p. 3052, doi. 10.3390/cancers13123052

By:

Cruz, Ana F.;
Caleiras, Mariana B.;
Fonseca, Nuno A.;
Gonçalves, Nélio;
Mendes, Vera M.;
Sampaio, Susana F.;
Moura, Vera;
Melo, Joana B.;
Almeida, Ramiro D.;
Manadas, Bruno;
Simões, Sérgio;
Moreira, João N.

Publication type:

Article

Caffeine and adenosine A(2A) receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado-Joseph disease.

Published in:

2013

By:

Gonçalves, Nélio;
Simoes, Ana T;
Cunha, Rodrigo A;
de Almeida, Luís Pereira;
Simões, Ana T

Publication type:

journal article

Caffeine and adenosine A2A receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado-Joseph disease.

Published in:

Annals of Neurology, 2013, v. 73, n. 5, p. 655, doi. 10.1002/ana.23866

By:

Gonçalves, Nélio;
Simões, Ana T.;
Cunha, Rodrigo A.;
Almeida, Luís Pereira

Publication type:

Article

Metabotropic glutamate type 5 receptor requires contactin-associated protein 1 to control memory formation.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 20, p. 3528, doi. 10.1093/hmg/ddy264

By:

Morató, Xavier;
Luján, Rafael;
Gonçalves, Nélio;
Watanabe, Masahiko;
Altafaj, Xavier;
Carvalho, Ana Luísa;
Fernández-Dueñas, Víctor;
Cunha, Rodrigo A;
Ciruela, Francisco

Publication type:

Article

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease.

Published in:

2012

By:

Simoes AT;
Gonçalves N;
Koeppen A;
Déglon N;
Kügler S;
Duarte CB;
Pereira de Almeida L;
Simões, Ana T;
Gonçalves, Nélio;
Koeppen, Arnulf;
Déglon, Nicole;
Kügler, Sebastian;
Duarte, Carlos Bandeira;
Pereira de Almeida, Luís

Publication type:

journal article

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado–Joseph disease.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 8, p. 2428, doi. 10.1093/brain/aws177

By:

Simões, Ana T.;
Gonçalves, Nélio;
Koeppen, Arnulf;
Déglon, Nicole;
Kügler, Sebastian;
Duarte, Carlos Bandeira;
Pereira de Almeida, Luís

Publication type:

Article

Propostas de modelos não lineares para ajuste da produção de gases in vitro em diferentes tempos de incubação em genótipos de mandioca.

Published in:

Revista Ciência e Natura, 2021, v. 43, p. 1, doi. 10.5902/2179460X39962

By:

Santos, André;
Rocha Moreira, Guilherme;
Gomes Silva, Frank;
Carlos Ramos de Brito, Cícero;
Lindomárcia Leonardo da Costa, Maria;
Cunha Filho, Moacyr;
de Oliveira Simões Saliba, Eloísa;
Caron de Oliveira, Marianne;
Cunha Gonçalves, Nélio

Publication type:

Article

Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microglia

Published in:

Journal of Neuroinflammation, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-2094-10-16

By:

Gomes, Catarina;
Ferreira, Raquel;
George, Jimmy;
Sanches, Rui;
Rodrigues, Diana I.;
Gonçalves, Nélio;
Cunha, Rodrigo A.

Publication type:

Article

Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microglia.

Published in:

2013

By:

Gomes, Catarina;
Ferreira, Raquel;
George, Jimmy;
Sanches, Rui;
Rodrigues, Diana I;
Gonçalves, Nélio;
Cunha, Rodrigo A

Publication type:

journal article

Early synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A2A receptors.

Published in:

Nature Communications, 2016, v. 7, n. 6, p. 11915, doi. 10.1038/ncomms11915

By:

Viana da Silva, Silvia;
Haberl, Matthias Georg;
Zhang, Pei;
Bethge, Philipp;
Lemos, Cristina;
Gonçalves, Nélio;
Gorlewicz, Adam;
Malezieux, Meryl;
Gonçalves, Francisco Q.;
Grosjean, Noëlle;
Blanchet, Christophe;
Frick, Andreas;
Nägerl, U Valentin;
Cunha, Rodrigo A.;
Mulle, Christophe

Publication type:

Article

Increased ATP Release and Higher Impact of Adenosine A2A Receptors on Corticostriatal Plasticity in a Rat Model of Presymptomatic Parkinson's Disease.

Published in:

Molecular Neurobiology, 2023, v. 60, n. 3, p. 1659, doi. 10.1007/s12035-022-03162-1

By:

Gonçalves, Francisco Q.;
Matheus, Filipe C.;
Silva, Henrique B.;
Real, Joana I.;
Rial, Daniel;
Rodrigues, Ricardo J.;
Oses, Jean-Pierre;
Silva, António C.;
Gonçalves, Nélio;
Prediger, Rui D.;
Tomé, Ângelo R.;
Cunha, Rodrigo A.

Publication type:

Article

Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 19, p. 5451, doi. 10.1093/hmg/ddv271

By:

Duarte-Neves, Joana;
Gonçalves, Nélio;
Cunha-Santos, Janete;
Simões, Ana Teresa;
den Dunnen, Wilfred F. A.;
Hirokazu Hirai;
Kügler, Sebastian;
Cavadas, Cláudia;
de Almeida, Luís Pereira

Publication type:

Article

Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado–Joseph disease.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 18, p. 4932, doi. 10.1093/hmg/ddu209

By:

Simões, Ana Teresa;
Gonçalves, Nélio;
Nobre, Rui Jorge;
Duarte, Carlos Bandeira;
Pereira de Almeida, Luís

Publication type:

Article

Adenosine A2A Receptors Contribute to the Radial Migration of Cortical Projection Neurons through the Regulation of Neuronal Polarization and Axon Formation.

Published in:

Cerebral Cortex, 2021, v. 31, n. 12, p. 5652, doi. 10.1093/cercor/bhab188

By:

Alçada-Morais, Sofia;
Gonçalves, Nélio;
Moreno-Juan, Verónica;
Andres, Belén;
Ferreira, Sofia;
Marques, Joana M;
Magalhães, Joana;
Rocha, João M M;
Xu, Xinli;
Partidário, Matilde;
Cunha, Rodrigo A;
López-Bendito, Guillermina;
Rodrigues, Ricardo J

Publication type:

Article

Cancer Stem Cells and Nucleolin as Drivers of Carcinogenesis.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 1, p. 60, doi. 10.3390/ph14010060

By:

Carvalho, Laura Sofia;
Gonçalves, Nélio;
Fonseca, Nuno André;
Moreira, João Nuno

Publication type:

Article

Adenosine A2A receptors control synaptic remodeling in the adult brain.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-18884-4

By:

Xu, Xinli;
Beleza, Rui O.;
Gonçalves, Francisco Q.;
Valbuena, Sergio;
Alçada-Morais, Sofia;
Gonçalves, Nélio;
Magalhães, Joana;
Rocha, João M. M.;
Ferreira, Sofia;
Figueira, Ana S. G.;
Lerma, Juan;
Cunha, Rodrigo A.;
Rodrigues, Ricardo J.;
Marques, Joana M.

Publication type:

Article

Depression as a Glial-Based Synaptic Dysfunction.

Published in:

Frontiers in Cellular Neuroscience, 2016, p. 1

By:

Rial, Daniel;
Lemos, Cristina;
Pinheiro, Helena;
Duarte, Joana M.;
Gonçalves, Francisco Q.;
Real, Joana I.;
Prediger, Rui D.;
Gonçalves, Nélio;
Gomes, Catarina A.;
Canas, Paula M.;
Agostinho, Paula;
Cunha, Rodrigo A.

Publication type:

Article

Works by Gonçalves, Nélio

Caffeine alleviates progressive motor deficits in a transgenic mouse model of spinocerebellar ataxia.

Nucleolin Overexpression Predicts Patient Prognosis While Providing a Framework for Targeted Therapeutic Intervention in Lung Cancer.

The Enhanced Efficacy of Intracellular Delivery of Doxorubicin/C6-Ceramide Combination Mediated by the F3 Peptide/Nucleolin System Is Supported by the Downregulation of the PI3K/Akt Pathway.

Caffeine and adenosine A(2A) receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado-Joseph disease.

Caffeine and adenosine A<sub>2A</sub> receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado-Joseph disease.

Metabotropic glutamate type 5 receptor requires contactin-associated protein 1 to control memory formation.

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease.

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado–Joseph disease.

Propostas de modelos não lineares para ajuste da produção de gases in vitro em diferentes tempos de incubação em genótipos de mandioca.

Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A<sub>2A</sub> receptor-dependent manner: A<sub>2A</sub> receptor blockade prevents BDNF release and proliferation of microglia

Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microglia.

Early synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A<sub>2A</sub> receptors.

Increased ATP Release and Higher Impact of Adenosine A<sub>2A</sub> Receptors on Corticostriatal Plasticity in a Rat Model of Presymptomatic Parkinson's Disease.

Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.

Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado–Joseph disease.

Adenosine A2A Receptors Contribute to the Radial Migration of Cortical Projection Neurons through the Regulation of Neuronal Polarization and Axon Formation.

Cancer Stem Cells and Nucleolin as Drivers of Carcinogenesis.

Adenosine A<sub>2A</sub> receptors control synaptic remodeling in the adult brain.

Depression as a Glial-Based Synaptic Dysfunction.