Works by Gombart, Adrian F

Results: 38

Low Plasma Level of Cathelicidin Antimicrobial Peptide (hCAP18) Predicts Increased Infectious Disease Mortality in Patients Undergoing Hemodialysis.

Published in:

Clinical Infectious Diseases, 2009, v. 48, n. 4, p. 418, doi. 10.1086/596314

By:

Gombart, Adrian F.;
Bhan, Ishir;
Borregaard, Niels;
Tamez, Hector;
Camargo, Jr., Carlos A.;
Koeffler, H. Phillip;
Thadhani, Ravi

Publication type:

Article

Expression of bactericidal/permeability-increasing protein requires C/EBP epsilon.

Published in:

2007

By:

Tanaka, Miyuki;
Gombart, Adrian;
Koeffler, H.;
Shiohara, Masaaki;
Gombart, Adrian F;
Koeffler, H Phillip

Publication type:

journal article

Interplay between HIV-1 infection and host microRNAs.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 5, p. 2181, doi. 10.1093/nar/gkr961

By:

Sun, Guihua;
Li, Haitang;
Wu, Xiwei;
Covarrubias, Maricela;
Scherer, Lisa;
Meinking, Keith;
Luk, Brian;
Chomchan, Pritsana;
Alluin, Jessica;
Gombart, Adrian F.;
Rossi, John J.

Publication type:

Article

Positive correlation between circulating cathelicidin antimicrobial peptide (hCAP18/LL-37) and 25-hydroxyvitamin D levels in healthy adults.

Published in:

BMC Research Notes, 2012, v. 5, n. 1, p. 575, doi. 10.1186/1756-0500-5-575

By:

Dixon, Brian M.;
Barker, Tyler;
McKinnon, Toni;
Cuomo, John;
Frei, Balz;
Borregaard, Niels;
Gombart, Adrian F.

Publication type:

Article

C/EBP∊ mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 9, p. 3316, doi. 10.1172/JCI62070

By:

Kyme, Pierre;
Thoennissen, Nils H.;
Ching Wen Tseng;
Thoennissen, Gabriela B.;
Wolf, Andrea J.;
Shimada, Kenichi;
Krug, Utz O.;
Lee, Kunik;
Müller-Tidow, Carsten;
Berdel, Wolfgang E.;
Hardy, W. David;
Gombart, Adrian F.;
Koeffler, H. Phillip;
Liu, George Y.

Publication type:

Article

Total synthesis of [13C]2-, [13C]3-, and [13C]5-isotopomers of xanthohumol, the principal prenylflavonoid from hops.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2017, v. 60, n. 14, p. 639, doi. 10.1002/jlcr.3571

By:

Ellinwood, Duncan C.;
El‐Mansy, Mohamed F.;
Plagmann, Layhna S.;
Stevens, Jan F.;
Maier, Claudia S.;
Gombart, Adrian F.;
Blakemore, Paul R.

Publication type:

Article

Micronutrients to Support Vaccine Immunogenicity and Efficacy.

Published in:

Vaccines, 2022, v. 10, n. 4, p. N.PAG, doi. 10.3390/vaccines10040568

By:

Calder, Philip C.;
Berger, Mette M.;
Gombart, Adrian F.;
McComsey, Grace A.;
Martineau, Adrian R.;
Eggersdorfer, Manfred

Publication type:

Article

Antiproliferative and Cytotoxic Activity of Xanthohumol and Its Non-Estrogenic Derivatives in Colon and Hepatocellular Carcinoma Cell Lines.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 5, p. 1203, doi. 10.3390/ijms20051203

By:

Logan, Isabelle E.;
Miranda, Cristobal L.;
Lowry, Malcolm B.;
Maier, Claudia S.;
Stevens, Jan F.;
Gombart, Adrian F.

Publication type:

Article

Tetrahydroxanthohumol, a xanthohumol derivative, attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARγ.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.66398

By:

Yang Zhang;
Bobe, Gerd;
Miranda, Cristobal L.;
Lowry, Malcolm B.;
Hsu, Victor L.;
Lohr, Christiane V.;
Wong, Carmen P.;
Jump, Donald B.;
Robinson, Matthew M.;
Sharpton, Thomas J.;
Maier, Claudia S.;
Stevens, Jan F.;
Gombart, Adrian F.

Publication type:

Article

Cytostatic effect of TNFα on cancer cells is independent of p21WAF1.

Published in:

Oncogene, 1997, v. 15, n. 13, p. 1605, doi. 10.1038/sj.onc.1201315

By:

Shiohara, Masaaki;
Gombart, Adrian F;
Berman, Jeffrey D;
Koike, Kenichi;
Komiyama, Atsushi;
Koeffler, H Phillip

Publication type:

Article

Identifying progression-associated genes in adult T-cell leukemia/lymphoma by using oligonucleotide microarrays.

Published in:

International Journal of Cancer, 2004, v. 109, n. 6, p. 875, doi. 10.1002/ijc.20028

By:

Kunihiro Tsukasaki;
Sakae Tanosaki;
Sven DeVos;
Wolf K. Hofmann;
William Wachsman;
Adrian F. Gombart;
Johannes Krebs;
Anna Jauch;
Claus R. Bartram;
Kazuhiro Nagai;
Masao Tomonaga;
Jonathan W. Said;
H. Phillip Koeffler

Publication type:

Article

Synergistic induction of human cathelicidin antimicrobial peptide gene expression by vitamin D and stilbenoids.

Published in:

Molecular Nutrition & Food Research, 2014, v. 58, n. 3, p. 528, doi. 10.1002/mnfr.201300266

By:

Guo, Chunxiao;
Sinnott, Brian;
Niu, Brenda;
Lowry, Malcolm B.;
Fantacone, Mary L.;
Gombart, Adrian F.

Publication type:

Article

Establishment of the acute myeloid leukemia cell line Kasumi-6 from a patient with a dominant-negative mutation in the DNA-binding region of the C/EBPα gene.

Published in:

Genes, Chromosomes & Cancer, 2003, v. 36, n. 2, p. 167, doi. 10.1002/gcc.10161

By:

Asou, Hiroya;
Gombart, Adrian F.;
Takeuchi, Seisho;
Tanaka, Hideo;
Tanioka, Maki;
Matsui, Hirotaka;
Kimura, Akiro;
Inaba, Toshiya;
Koeffler, H. Phillip

Publication type:

Article

Alterations of CDKN2 (p16) in non-small cell lung cancer.

Published in:

Genes, Chromosomes & Cancer, 1995, v. 14, n. 3, p. 164, doi. 10.1002/gcc.2870140303

By:

Vos, Sven De;
Miller, Carl W.;
Takeuchi, Seisho;
Gombart, Adrian F.;
Cho, Steve K.;
Koeffler, H. Phillip

Publication type:

Article

There is no evidence that vitamin D supplementation drives the progression of Alzheimer's disease.

Published in:

Aging Cell, 2023, v. 22, n. 1, p. 1, doi. 10.1111/acel.13758

By:

Gombart, Adrian F.;
Michels, Alexander J.;
Eggersdorfer, Manfred

Publication type:

Article

Multi-Level Immune Support by Vitamins C and D during the SARS-CoV-2 Pandemic.

Published in:

2022

By:

Carr, Anitra C.;
Gombart, Adrian F.

Publication type:

Editorial

Reply to "Overstated Claims of Efficacy and Safety. Comment On: Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections. Nutrients 2020, 12 , 1181".

Published in:

2020

By:

Calder, Philip C.;
Carr, Anitra C.;
Gombart, Adrian F.;
Eggersdorfer, Manfred

Publication type:

Letter to the Editor

The Effect of a Multivitamin and Mineral Supplement on Immune Function in Healthy Older Adults: A Double-Blind, Randomized, Controlled Trial.

Published in:

Nutrients, 2020, v. 12, n. 8, p. 2447, doi. 10.3390/nu12082447

By:

Fantacone, Mary L.;
Lowry, Malcolm B.;
Uesugi, Sandra L.;
Michels, Alexander J.;
Choi, Jaewoo;
Leonard, Scott W.;
Gombart, Sean K.;
Gombart, Jeffrey S.;
Bobe, Gerd;
Gombart, Adrian F.

Publication type:

Article

Reply to "Comment on: Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections. Nutrients 2020, 12, 1181".

Published in:

2020

By:

Calder, Philip C.;
Carr, Anitra C.;
Gombart, Adrian F.;
Eggersdorfer, Manfred

Publication type:

Letter

Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections.

Published in:

Nutrients, 2020, v. 12, n. 4, p. 1181, doi. 10.3390/nu12041181

By:

Calder, Philip C.;
Carr, Anitra C.;
Gombart, Adrian F.;
Eggersdorfer, Manfred

Publication type:

Article

A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection.

Published in:

Nutrients, 2020, v. 12, n. 1, p. 236, doi. 10.3390/nu12010236

By:

Gombart, Adrian F.;
Pierre, Adeline;
Maggini, Silvia

Publication type:

Article

The anti-proliferative effects of 1α,25(OH)2D3 on breast and prostate cancer cells are associated with induction of BRCA1 gene expression.

Published in:

Oncogene, 2000, v. 19, n. 44, p. 5091, doi. 10.1038/sj.onc.1203888

By:

Campbell, Moray J;
Gombart, Adrian F;
Kwok, Scott H;
Park, Susan;
Koeffler, H Phillip

Publication type:

Article

Xanthohumol Requires the Intestinal Microbiota to Improve Glucose Metabolism in Diet‐Induced Obese Mice.

Published in:

Molecular Nutrition & Food Research, 2021, v. 65, n. 21, p. 1, doi. 10.1002/mnfr.202100389

By:

Logan, Isabelle E.;
Shulzhenko, Natalia;
Sharpton, Thomas J.;
Bobe, Gerd;
Liu, Kitty;
Nuss, Stephanie;
Jones, Megan L.;
Miranda, Cristobal L.;
Vasquez‐Perez, Stephany;
Pennington, Jamie M.;
Leonard, Scott W.;
Choi, Jaewoo;
Wu, Wenbin;
Gurung, Manoj;
Kim, Joyce P.;
Lowry, Malcolm B.;
Morgun, Andrey;
Maier, Claudia S.;
Stevens, Jan F.;
Gombart, Adrian F.

Publication type:

Article

Targeting the Liver‐Brain Axis with Hop‐Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice.

Published in:

Molecular Nutrition & Food Research, 2020, v. 64, n. 15, p. 1, doi. 10.1002/mnfr.202000341

By:

Paraiso, Ines L.;
Revel, Johana S.;
Choi, Jaewoo;
Miranda, Cristobal L.;
Lak, Parnian;
Kioussi, Chrissa;
Bobe, Gerd;
Gombart, Adrian F.;
Raber, Jacob;
Maier, Claudia S.;
Stevens, Jan F.

Publication type:

Article

Front Cover: Targeting the Liver‐Brain Axis with Hop‐Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice.

Published in:

Molecular Nutrition & Food Research, 2020, v. 64, n. 15, p. 1, doi. 10.1002/mnfr.202070034

By:

Paraiso, Ines L.;
Revel, Johana S.;
Choi, Jaewoo;
Miranda, Cristobal L.;
Lak, Parnian;
Kioussi, Chrissa;
Bobe, Gerd;
Gombart, Adrian F.;
Raber, Jacob;
Maier, Claudia S.;
Stevens, Jan F.

Publication type:

Article

Improvements in Metabolic Syndrome by Xanthohumol Derivatives Are Linked to Altered Gut Microbiota and Bile Acid Metabolism.

Published in:

Molecular Nutrition & Food Research, 2020, v. 64, n. 1, p. N.PAG, doi. 10.1002/mnfr.201900789

By:

Zhang, Yang;
Bobe, Gerd;
Revel, Johana S.;
Rodrigues, Richard R.;
Sharpton, Thomas J.;
Fantacone, Mary L.;
Raslan, Kareem;
Miranda, Cristobal L.;
Lowry, Malcolm B.;
Blakemore, Paul R.;
Morgun, Andrey;
Shulzhenko, Natalia;
Maier, Claudia S.;
Stevens, Jan F.;
Gombart, Adrian F.

Publication type:

Article

Front Cover: Improvements in Metabolic Syndrome by Xanthohumol Derivatives Are Linked to Altered Gut Microbiota and Bile Acid Metabolism.

Published in:

Molecular Nutrition & Food Research, 2020, v. 64, n. 1, p. N.PAG, doi. 10.1002/mnfr.202070003

By:

Zhang, Yang;
Bobe, Gerd;
Revel, Johana S.;
Rodrigues, Richard R.;
Sharpton, Thomas J.;
Fantacone, Mary L.;
Raslan, Kareem;
Miranda, Cristobal L.;
Lowry, Malcolm B.;
Blakemore, Paul R.;
Morgun, Andrey;
Shulzhenko, Natalia;
Maier, Claudia S.;
Stevens, Jan F.;
Gombart, Adrian F.

Publication type:

Article

Reductive Metabolism of Xanthohumol and 8‐Prenylnaringenin by the Intestinal Bacterium Eubacterium ramulus.

Published in:

Molecular Nutrition & Food Research, 2019, v. 63, n. 2, p. N.PAG, doi. 10.1002/mnfr.201800923

By:

Paraiso, Ines L.;
Plagmann, Layhna S.;
Yang, Liping;
Zielke, Ryszard;
Gombart, Adrian F.;
Maier, Claudia S.;
Sikora, Aleksandra E.;
Blakemore, Paul R.;
Stevens, Jan F.

Publication type:

Article

Back cover: Reductive Metabolism of Xanthohumol and 8‐Prenylnaringenin by the Intestinal Bacterium Eubacterium ramulus.

Published in:

Molecular Nutrition & Food Research, 2019, v. 63, n. 2, p. N.PAG, doi. 10.1002/mnfr.201970006

By:

Paraiso, Ines L.;
Plagmann, Layhna S.;
Yang, Liping;
Zielke, Ryszard;
Gombart, Adrian F.;
Maier, Claudia S.;
Sikora, Aleksandra E.;
Blakemore, Paul R.;
Stevens, Jan F.

Publication type:

Article

Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3.

Published in:

FASEB Journal, 2005, v. 19, n. 9, p. 1067, doi. 10.1096/fj.04-3284com

By:

Gombart, Adrian F.;
Borregaard, Niels;
Koeffler, H. Phillip

Publication type:

Article

Engineered Exosomes Containing Cathelicidin/LL‐37 Exhibit Multiple Biological Functions.

Published in:

Advanced Healthcare Materials, 2022, v. 11, n. 20, p. 1, doi. 10.1002/adhm.202200849

By:

Su, Yajuan;
Sharma, Navatha Shree;
John, Johnson V.;
Ganguli‐Indra, Gitali;
Indra, Arup K.;
Gombart, Adrian F.;
Xie, Jingwei

Publication type:

Article

Deficiency of CCAAT/Enhancer Binding Protein-Epsilon Reduces Atherosclerotic Lesions in LDLR−/− Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0085341

By:

Okamoto, Ryoko;
Gery, Sigal;
Gombart, Adrian F.;
Wang, Xuping;
Castellani, Lawrence W.;
Akagi, Tadayuki;
Chen, Shuang;
Arditi, Moshe;
Ho, Quoc;
Lusis, Aldons J.;
Li, Quanlin;
Koeffler, H. Phillip

Publication type:

Article

In Vivo Deficiency of Both C/EBPβ and C/EBPϵ Results in Highly Defective Myeloid Differentiation and Lack of Cytokine Response.

Published in:

PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0015419

By:

Akagi, Tadayuki;
Thoennissen, Nils H.;
George, Ann;
Crooks, Gay;
Jee Hoon Song;
Okamoto, Ryoko;
Nowak, Daniel;
Gombart, Adrian F.;
Koeffler, H. Phillip

Publication type:

Article

C/EBPα and the Vitamin D Receptor Cooperate in the Regulation of Cathelicidin in Lung Epithelial Cells.

Published in:

Journal of Cellular Physiology, 2015, v. 230, n. 2, p. 464, doi. 10.1002/jcp.24729

By:

Dhawan, Puneet;
Wei, Ran;
Sun, Cheng;
Gombart, Adrian F.;
Koeffler, H. Phillip;
Diamond, Gill;
Christakos, Sylvia

Publication type:

Article

Tumor necrosis factor α: Posttranscriptional stabilization of WAF1 mRNA in p53-deficient human leukemic cells.

Published in:

Journal of Cellular Physiology, 1996, v. 166, n. 3, p. 568, doi. 10.1002/(SICI)1097-4652(199603)166:3<568::AID-JCP11>3.0.CO;2-3

By:

Shiohara, Masaaki;
Akashi, Makoto;
Gombart, Adrian F.;
Yang, Rong;
Koeffler, H. Phillip

Publication type:

Article

Germ-Free Swiss Webster Mice on a High-Fat Diet Develop Obesity, Hyperglycemia, and Dyslipidemia.

Published in:

Microorganisms, 2020, v. 8, n. 4, p. 520, doi. 10.3390/microorganisms8040520

By:

Logan, Isabelle E.;
Bobe, Gerd;
Miranda, Cristobal L.;
Vasquez-Perez, Stephany;
Choi, Jaewoo;
Lowry, Malcolm B.;
Sharpton, Thomas J.;
Morgun, Andrey;
Maier, Claudia S.;
Stevens, Jan F.;
Shulzhenko, Natalia;
Gombart, Adrian F.

Publication type:

Article

Upregulating Human Cathelicidin Antimicrobial Peptide LL-37 Expression May Prevent Severe COVID-19 Inflammatory Responses and Reduce Microthrombosis.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.880961

By:

Aloul, Karim M.;
Nielsen, Josefine Eilsø;
Defensor, Erwin B.;
Lin, Jennifer S.;
Fortkort, John A.;
Shamloo, Mehrdad;
Cirillo, Jeffrey D.;
Gombart, Adrian F.;
Barron, Annelise E.

Publication type:

Article

Exaptation of an ancient Alu short interspersed element provides ahighly conserved vitamin D-mediated innate immune response inhumans and primates.

Published in:

BMC Genomics, 2009, v. 10, p. 321, doi. 10.1186/1471-2164-10-321

By:

Gombart, Adrian F.;
Saito, Tsuyako;
Koeffler, H. Phillip

Publication type:

Article

Works by Gombart, Adrian F

Low Plasma Level of Cathelicidin Antimicrobial Peptide (hCAP18) Predicts Increased Infectious Disease Mortality in Patients Undergoing Hemodialysis.

Expression of bactericidal/permeability-increasing protein requires C/EBP epsilon.

Interplay between HIV-1 infection and host microRNAs.

Positive correlation between circulating cathelicidin antimicrobial peptide (hCAP18/LL-37) and 25-hydroxyvitamin D levels in healthy adults.

C/EBP∊ mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice.

Total synthesis of [<sup>13</sup>C]<sub>2</sub>-, [<sup>13</sup>C]<sub>3</sub>-, and [<sup>13</sup>C]<sub>5</sub>-isotopomers of xanthohumol, the principal prenylflavonoid from hops.

Micronutrients to Support Vaccine Immunogenicity and Efficacy.

Antiproliferative and Cytotoxic Activity of Xanthohumol and Its Non-Estrogenic Derivatives in Colon and Hepatocellular Carcinoma Cell Lines.

Tetrahydroxanthohumol, a xanthohumol derivative, attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARγ.

Cytostatic effect of TNFα on cancer cells is independent of p21<sup>WAF1</sup>.

Identifying progression-associated genes in adult T-cell leukemia/lymphoma by using oligonucleotide microarrays.

Synergistic induction of human cathelicidin antimicrobial peptide gene expression by vitamin D and stilbenoids.

Establishment of the acute myeloid leukemia cell line Kasumi-6 from a patient with a dominant-negative mutation in the DNA-binding region of the C/EBPα gene.

Alterations of CDKN2 (p16) in non-small cell lung cancer.

There is no evidence that vitamin D supplementation drives the progression of Alzheimer's disease.

Multi-Level Immune Support by Vitamins C and D during the SARS-CoV-2 Pandemic.

Reply to "Overstated Claims of Efficacy and Safety. Comment On: Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections. Nutrients 2020, 12 , 1181".

The Effect of a Multivitamin and Mineral Supplement on Immune Function in Healthy Older Adults: A Double-Blind, Randomized, Controlled Trial.

Reply to "Comment on: Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections. Nutrients 2020, 12, 1181".

Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections.

A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection.

The anti-proliferative effects of 1α,25(OH)<sub>2</sub>D<sub>3</sub> on breast and prostate cancer cells are associated with induction of BRCA1 gene expression.

Xanthohumol Requires the Intestinal Microbiota to Improve Glucose Metabolism in Diet‐Induced Obese Mice.

Targeting the Liver‐Brain Axis with Hop‐Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice.

Front Cover: Targeting the Liver‐Brain Axis with Hop‐Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice.

Improvements in Metabolic Syndrome by Xanthohumol Derivatives Are Linked to Altered Gut Microbiota and Bile Acid Metabolism.

Front Cover: Improvements in Metabolic Syndrome by Xanthohumol Derivatives Are Linked to Altered Gut Microbiota and Bile Acid Metabolism.

Reductive Metabolism of Xanthohumol and 8‐Prenylnaringenin by the Intestinal Bacterium Eubacterium ramulus.

Back cover: Reductive Metabolism of Xanthohumol and 8‐Prenylnaringenin by the Intestinal Bacterium Eubacterium ramulus.

Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D<sub>3</sub>.

Engineered Exosomes Containing Cathelicidin/LL‐37 Exhibit Multiple Biological Functions.

Deficiency of CCAAT/Enhancer Binding Protein-Epsilon Reduces Atherosclerotic Lesions in LDLR−/− Mice.

In Vivo Deficiency of Both C/EBPβ and C/EBP<sub>ϵ</sub> Results in Highly Defective Myeloid Differentiation and Lack of Cytokine Response.

C/EBPα and the Vitamin D Receptor Cooperate in the Regulation of Cathelicidin in Lung Epithelial Cells.

Tumor necrosis factor α: Posttranscriptional stabilization of WAF1 mRNA in p53-deficient human leukemic cells.

Germ-Free Swiss Webster Mice on a High-Fat Diet Develop Obesity, Hyperglycemia, and Dyslipidemia.

Upregulating Human Cathelicidin Antimicrobial Peptide LL-37 Expression May Prevent Severe COVID-19 Inflammatory Responses and Reduce Microthrombosis.

Exaptation of an ancient Alu short interspersed element provides ahighly conserved vitamin D-mediated innate immune response inhumans and primates.