Works by Golub, Todd R


Results: 65
    1

    A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay.

    Published in:
    GigaScience, 2017, v. 6, n. 12, p. 1, doi. 10.1093/gigascience/giw014
    By:
    • Bray, Mark-Anthony;
    • Gustafsdottir, Sigrun M.;
    • Rohban, Mohammad H.;
    • Singh, Shantanu;
    • Ljosa, Vebjorn;
    • Sokolnicki, Katherine L.;
    • Bittker, Joshua A.;
    • Bodycombe, Nicole E.;
    • Dančík, Vlado;
    • Hasaka, Thomas P.;
    • Hon, Cindy S.;
    • Kemp, Melissa M.;
    • Kejie Li;
    • Walpita, Deepika;
    • Wawer, Mathias J.;
    • Golub, Todd R.;
    • Schreiber, Stuart L.;
    • Clemons, Paul A.;
    • Shamji, Alykhan F.;
    • Carpenter, Anne E.
    Publication type:
    Article
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    BRAF mutation predicts sensitivity to MEK inhibition.

    Published in:
    Nature, 2006, v. 439, n. 7074, p. 358, doi. 10.1038/nature04304
    By:
    • Solit, David B.;
    • Garraway, Levi A.;
    • Pratilas, Christine A.;
    • Sawai, Ayana;
    • Getz, Gad;
    • Basso, Andrea;
    • Qing Ye;
    • Lobo, Jose M.;
    • Yuhong She;
    • Osman, Iman;
    • Golub, Todd R.;
    • Sebolt-Leopold, Judith;
    • Sellers, William R.;
    • Rosen, Neal
    Publication type:
    Article
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    MicroRNA expression profiles classify human cancers.

    Published in:
    Nature, 2005, v. 435, n. 7043, p. 834, doi. 10.1038/nature03702
    By:
    • Lu, Jun;
    • Getz, Gad;
    • Miska, Eric A.;
    • Alvarez-Saavedra, Ezequiel;
    • Lamb, Justin;
    • Peck, David;
    • Sweet-Cordero, Alejandro;
    • Ebert, Benjamin L.;
    • Mak, Raymond H.;
    • Ferrando, Adolfo A.;
    • Downing, James R.;
    • Jacks, Tyler;
    • Horvitz, H. Robert;
    • Golub, Todd R.
    Publication type:
    Article
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    PGC-1a-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.

    Published in:
    Nature Genetics, 2003, v. 34, n. 3, p. 267, doi. 10.1038/ng1180
    By:
    • Mootha, Vamsi K;
    • Lindgren, Cecilia M;
    • Eriksson, Karl-Fredrik;
    • Subramanian, Aravind;
    • Sihag, Smita;
    • Lehar, Joseph;
    • Puigserver, Pere;
    • Carlsson, Emma;
    • Ridderstrale, Martin;
    • Laurila, Esa;
    • Houstis, Nicholas;
    • Daly, Mark J;
    • Patterson, Nick;
    • Mesirov, Jill P;
    • Golub, Todd R;
    • Tamayo, Pablo;
    • Spiegelman, Bruce;
    • Lander, Eric S;
    • Hirschhorn, Joel N
    Publication type:
    Article
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    A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers.

    Published in:
    Journal of Clinical Investigation, 2012, v. 122, n. 8, p. 2983, doi. 10.1172/JCI64400
    By:
    • Lee, Ryan S.;
    • Stewart, Chip;
    • Carter, Scott L.;
    • Ambrogio, Lauren;
    • Cibulskis, Kristian;
    • Sougnez, Carrie;
    • Lawrence, Michael S.;
    • Auclair, Daniel;
    • Mora, Jaume;
    • Golub, Todd R.;
    • Biegel, Jaclyn A.;
    • Getz, Gad;
    • Roberts, Charles W. M.
    Publication type:
    Article
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    The genomic landscape of juvenile myelomonocytic leukemia.

    Published in:
    Nature Genetics, 2015, v. 47, n. 11, p. 1326, doi. 10.1038/ng.3400
    By:
    • Toretsky, Jeffrey A;
    • Olshen, Adam B;
    • Getz, Gad;
    • Gruber, Tanja A;
    • Golub, Todd R;
    • Stegmaier, Kimberly;
    • Loh, Mignon L;
    • Stieglitz, Elliot;
    • Chang, Tiffany Y;
    • Gelston, Laura C;
    • Esquivel, Emilio;
    • Yu, Ariel;
    • Archambeault, Sophie L;
    • Beckman, Kyle;
    • Cooper, Todd;
    • Dahl, Gary V;
    • Emanuel, Peter D;
    • Liu, Y Lucy;
    • Fluchel, Mark N;
    • Goyal, Rakesh K
    Publication type:
    Article
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    Liquid biopsy detection of genomic alterations in pediatric brain tumors from cell-free DNA in peripheral blood, CSF, and urine.

    Published in:
    Neuro-Oncology, 2022, v. 24, n. 8, p. 1352, doi. 10.1093/neuonc/noab299
    By:
    • Pagès, Mélanie;
    • Rotem, Denisse;
    • Gydush, Gregory;
    • Reed, Sarah;
    • Rhoades, Justin;
    • Ha, Gavin;
    • Lo, Christopher;
    • Fleharty, Mark;
    • Duran, Madeleine;
    • Jones, Robert;
    • Becker, Sarah;
    • Haller, Michaela;
    • Sinai, Claire E;
    • Goumnerova, Liliana;
    • Golub, Todd R;
    • Love, J Christopher;
    • Ligon, Keith L;
    • Wright, Karen D;
    • Adalsteinsson, Viktor A;
    • Beroukhim, Rameen
    Publication type:
    Article
    26

    Systematic profiling of conditional degron tag technologies for target validation studies.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33246-4
    By:
    • Bondeson, Daniel P.;
    • Mullin-Bernstein, Zachary;
    • Oliver, Sydney;
    • Skipper, Thomas A.;
    • Atack, Thomas C.;
    • Bick, Nolan;
    • Ching, Meilani;
    • Guirguis, Andrew A.;
    • Kwon, Jason;
    • Langan, Carly;
    • Millson, Dylan;
    • Paolella, Brenton R.;
    • Tran, Kevin;
    • Wie, Sarah J.;
    • Vazquez, Francisca;
    • Tothova, Zuzana;
    • Golub, Todd R.;
    • Sellers, William R.;
    • Ianari, Alessandra
    Publication type:
    Article
    27

    Genetic interrogation of circulating multiple myeloma cells at single-cell resolution.

    Published in:
    Science Translational Medicine, 2016, v. 8, n. 363, p. 1, doi. 10.1126/scitranslmed.aac7037
    By:
    • Lohr, Jens G.;
    • Sora Kim;
    • Gould, Joshua;
    • Knoechel, Birgit;
    • Drier, Yotam;
    • Cotton, Matthew J.;
    • Gray, Daniel;
    • Birrer, Nicole;
    • Bang Wong;
    • Gavin Ha;
    • Cheng-Zhong Zhang;
    • Guangwu Guo;
    • Meyerson, Matthew;
    • Yee, Andrew J.;
    • Boehm, Jesse S.;
    • Raje, Noopur;
    • Golub, Todd R.
    Publication type:
    Article
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    Stem cell gene expression programs influence clinical outcome in human leukemia.

    Published in:
    Nature Medicine, 2011, v. 17, n. 9, p. 1086, doi. 10.1038/nm.2415
    By:
    • Eppert, Kolja;
    • Takenaka, Katsuto;
    • Lechman, Eric R;
    • Waldron, Levi;
    • Nilsson, Björn;
    • van Galen, Peter;
    • Metzeler, Klaus H;
    • Poeppl, Armando;
    • Ling, Vicki;
    • Beyene, Joseph;
    • Canty, Angelo J;
    • Danska, Jayne S;
    • Bohlander, Stefan K;
    • Buske, Christian;
    • Minden, Mark D;
    • Golub, Todd R;
    • Jurisica, Igor;
    • Ebert, Benjamin L;
    • Dick, John E
    Publication type:
    Article
    38

    Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.

    Published in:
    EMBO Journal, 2005, v. 24, n. 2, p. 368, doi. 10.1038/sj.emboj.7600521
    By:
    • Wang, Jing;
    • Iwasaki, Hiromi;
    • Krivtsov, Andrei;
    • Febbo, Phillip G.;
    • Thorner, Aaron R.;
    • Ernst, Patricia;
    • Anastasiadou, Ema;
    • Kutok, Jeffery L.;
    • Kogan, Scott C.;
    • Zinkel, Sandra S.;
    • Fisher, Jill K.;
    • Hess, Jay L.;
    • Golub, Todd R.;
    • Armstrong, Scott A.;
    • Akashi, Koichi;
    • Korsmeyer, Stanley J.
    Publication type:
    Article
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    Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-17440-w
    By:
    • McFarland, James M.;
    • Paolella, Brenton R.;
    • Warren, Allison;
    • Geiger-Schuller, Kathryn;
    • Shibue, Tsukasa;
    • Rothberg, Michael;
    • Kuksenko, Olena;
    • Colgan, William N.;
    • Jones, Andrew;
    • Chambers, Emily;
    • Dionne, Danielle;
    • Bender, Samantha;
    • Wolpin, Brian M.;
    • Ghandi, Mahmoud;
    • Tirosh, Itay;
    • Rozenblatt-Rosen, Orit;
    • Roth, Jennifer A.;
    • Golub, Todd R.;
    • Regev, Aviv;
    • Aguirre, Andrew J.
    Publication type:
    Article
    45

    A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.

    Published in:
    PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0125010
    By:
    • Clifton, Matthew C.;
    • Dranow, David M.;
    • Leed, Alison;
    • Fulroth, Ben;
    • Fairman, James W.;
    • Abendroth, Jan;
    • Atkins, Kateri A.;
    • Wallace, Ellen;
    • Fan, Dazhong;
    • Xu, Guoping;
    • Ni, Z. J.;
    • Daniels, Doug;
    • Van Drie, John;
    • Wei, Guo;
    • Burgin, Alex B.;
    • Golub, Todd R.;
    • Hubbard, Brian K.;
    • Serrano-Wu, Michael H.
    Publication type:
    Article
    46

    Multiplex Cytological Profiling Assay to Measure Diverse Cellular States.

    Published in:
    PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0080999
    By:
    • Gustafsdottir, Sigrun M.;
    • Ljosa, Vebjorn;
    • Sokolnicki, Katherine L.;
    • Anthony Wilson, J.;
    • Walpita, Deepika;
    • Kemp, Melissa M.;
    • Petri Seiler, Kathleen;
    • Carrel, Hyman A.;
    • Golub, Todd R.;
    • Schreiber, Stuart L.;
    • Clemons, Paul A.;
    • Carpenter, Anne E.;
    • Shamji, Alykhan F.
    Publication type:
    Article
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    Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion.

    Published in:
    Nature, 2012, v. 487, n. 7408, p. 500, doi. 10.1038/nature11183
    By:
    • Straussman, Ravid;
    • Morikawa, Teppei;
    • Shee, Kevin;
    • Barzily-Rokni, Michal;
    • Qian, Zhi Rong;
    • Du, Jinyan;
    • Davis, Ashli;
    • Mongare, Margaret M.;
    • Gould, Joshua;
    • Frederick, Dennie T.;
    • Cooper, Zachary A.;
    • Chapman, Paul B.;
    • Solit, David B.;
    • Ribas, Antoni;
    • Lo, Roger S.;
    • Flaherty, Keith T.;
    • Ogino, Shuji;
    • Wargo, Jennifer A.;
    • Golub, Todd R.
    Publication type:
    Article