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Study design for development of novel safety biomarkers of drug-induced liver injury by the translational safety biomarker pipeline (TransBioLine) consortium: a study protocol for a nested case–control study.
- Published in:
- Diagnostic & Prognostic Research, 2023, v. 7, n. 1, p. 1, doi. 10.1186/s41512-023-00155-z
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- Publication type:
- Article
Study design for development of novel safety biomarkers of drug-induced liver injury by the translational safety biomarker pipeline (TransBioLine) consortium: a study protocol for a nested case–control study.
- Published in:
- Diagnostic & Prognostic Research, 2023, v. 7, n. 1, p. 1, doi. 10.1186/s41512-023-00155-z
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- Publication type:
- Article
VEGF Stimulates Activation of ERK5 in the Absence of C-Terminal Phosphorylation Preventing Nuclear Localization and Facilitating AKT Activation in Endothelial Cells.
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- Cells (2073-4409), 2023, v. 12, n. 6, p. 967, doi. 10.3390/cells12060967
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- Article
The Generation, Detection, and Effects of Reactive Drug Metabolites.
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- Medicinal Research Reviews, 2013, v. 33, n. 5, p. 985, doi. 10.1002/med.21273
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- Article
The role of ERK5 in endothelial cell function.
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- Biochemical Society Transactions, 2014, v. 42, n. 6, p. 1584, doi. 10.1042/BST20140276
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- Publication type:
- Article
A MicroRNA Next-Generation-Sequencing Discovery Assay (miND) for Genome-Scale Analysis and Absolute Quantitation of Circulating MicroRNA Biomarkers.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1226, doi. 10.3390/ijms23031226
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- Article
In vivo Footprinting of the Mouse Inducible Nitric Oxide Synthase Gene: Inducible Protein Occupation of Numerous Sites Including Oct and NF-IL6.
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- Nucleic Acids Research, 1996, v. 24, n. 9, p. 1682, doi. 10.1093/nar/24.9.1682
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- Article
Development of an orthotopic syngeneic murine model of colorectal cancer for use in translational research.
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- Laboratory Animals, 2019, v. 53, n. 6, p. 598, doi. 10.1177/0023677219826165
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- Article
Critical considerations for targeting colorectal liver metastases with nanotechnology.
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- WIREs: Nanomedicine & Nanobiotechnology, 2020, v. 12, n. 2, p. N.PAG, doi. 10.1002/wnan.1588
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- Publication type:
- Article
Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds.
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- NPJ Systems Biology & Applications, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41540-018-0058-z
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- Publication type:
- Article
Circulating levels of miR-122 increase post-mortem, particularly following lethal dosing with pentobarbital sodium: implications for pre-clinical liver injury studies.
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- Toxicology Research, 2017, v. 6, n. 4, p. 406, doi. 10.1039/c6tx00442c
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- Publication type:
- Article
Glutathione- S-transferase pi as a model protein for the characterisation of chemically reactive metabolites.
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- Proteomics, 2008, v. 8, n. 2, p. 301, doi. 10.1002/pmic.200700843
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- Publication type:
- Article
Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury.
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- Archives of Toxicology, 2019, v. 93, n. 2, p. 385, doi. 10.1007/s00204-018-2354-1
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- Article
Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease.
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- Scientific Reports, 2016, p. 25187, doi. 10.1038/srep25187
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- Article
Application of porcine gastrointestinal organoid units as a potential in vitro tool for drug discovery and development.
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- Journal of Applied Toxicology, 2019, v. 39, n. 1, p. 4, doi. 10.1002/jat.3641
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- Article
Early detection of paracetamol toxicity using circulating liver microRNA and markers of cell necrosis.
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- British Journal of Clinical Pharmacology, 2014, v. 77, n. 5, p. 904, doi. 10.1111/bcp.12214
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- Article
Extract of Ginkgo biloba induces glutamate cysteine ligase catalytic subunit (GCLC).
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- Phytotherapy Research, 2008, v. 22, n. 3, p. 367, doi. 10.1002/ptr.2328
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- Publication type:
- Article
Characterization of Drug-Specific Signaling Between Primary Human Hepatocytes and Immune Cells.
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- Toxicological Sciences, 2017, v. 158, n. 1, p. 76, doi. 10.1093/toxsci/kfx069
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- Publication type:
- Article
Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication.
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- Toxicological Sciences, 2015, v. 147, n. 2, p. 412, doi. 10.1093/toxsci/kfv136
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- Article
Chemical Tuning Enhances Both Potency Toward Nrf2 and In Vitro Therapeutic Index of Triterpenoids.
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- Toxicological Sciences, 2014, v. 140, n. 2, p. 462, doi. 10.1093/toxsci/kfu080
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- Publication type:
- Article
Safety perspectives on presently considered drugs for the treatment of COVID-19.
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- 2020
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- Publication type:
- journal article
Hyporesponsiveness to lipopolysaccharide alters the composition of NF-κB binding to the regulatory regions of inducible nitric oxide synthase gene.
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- European Journal of Immunology, 1998, v. 28, n. 9, p. 2960, doi. 10.1002/(SICI)1521-4141(199809)28:09<2960::AID-IMMU2960>3.0.CO;2-B
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- Article