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Adeno-associated virus delivered CXCL9 sensitizes glioblastoma to anti-PD-1 immune checkpoint blockade.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49989-1
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- Article
Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 4043, doi. 10.1002/alz.13821
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- Article
Clinical utility of plasma Aβ42/40 ratio by LC-MS/MS in Alzheimer's disease assessment.
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- Frontiers in Neurology, 2024, p. 01, doi. 10.3389/fneur.2024.1364658
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Immune modulatory therapeutics in AD ‐ can we find the Goldilocks zone?
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.072029
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- Article
Uncovering Novel Modifiers of Tau Aggregation and Pathology using a Proximity Proteomics Approach (BioID).
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079920
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- Article
Evaluating dynamic autophagic responses to tau inclusions.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074246
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Network‐based pipeline guides knowledge‐driven prioritization and validation of therapeutic target discovery for Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073832
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- Article
Integrative omics studies to discover genetic determinants of brain cell type proportions.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080786
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Network‐based pipeline guides knowledge‐driven prioritization and validation of therapeutic target discovery for Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.073832
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- Article
Integrative omics studies to discover genetic determinants of brain cell type proportions.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080786
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- Article
Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42626-3
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- Article
Brain Targeted AAV1-GALC Gene Therapy Reduces Psychosine and Extends Lifespan in a Mouse Model of Krabbe Disease.
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- Genes, 2023, v. 14, n. 8, p. 1517, doi. 10.3390/genes14081517
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- Article
Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance.
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- NPJ Parkinson's Disease, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41531-022-00434-4
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- Article
Chimeric Phagocytic Receptors (CPR) to target Alzheimer's disease pathology.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.068704
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- Article
Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy.
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- Molecular Neurodegeneration, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13024-022-00585-1
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- Article
Investigating the functional significance of presynaptic tau in ageing and disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.065852
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- Article
Identification of Novel Modifiers of Tau Aggregation and Pathology using a Proximity Proteomics Approach.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.065671
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- Article
Common features of neurodegenerative disease: exploring the brain-eye connection and beyond (part 2): the 2021 pre-symposium of the 15th international conference on Alzheimer's and Parkinson's diseases.
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- Molecular Neurodegeneration, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13024-022-00571-7
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- Article
Common features of neurodegenerative disease: exploring the brain-eye connection and beyond (Part 1): the 2021 pre-symposium of the 15th international conference on Alzheimer's and Parkinson's diseases.
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- Molecular Neurodegeneration, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13024-022-00571-7
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- Article
LRP1 is a neuronal receptor for α-synuclein uptake and spread.
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- Molecular Neurodegeneration, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13024-022-00560-w
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- Article
Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways.
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- Alzheimer's Research & Therapy, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13195-022-01044-1
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Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice.
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- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03373-1
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Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09825-2
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- Article
AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model.
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- EMBO Molecular Medicine, 2022, v. 14, n. 4, p. 1, doi. 10.15252/emmm.201809824
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Intracerebral but Not Peripheral Infection of Live Porphyromonas gingivalis Exacerbates Alzheimer's Disease Like Amyloid Pathology in APP-TgCRND8 Mice.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 6, p. 3328, doi. 10.3390/ijms23063328
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Alzheimer's disease – the journey of a healthy brain into organ failure.
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- Molecular Neurodegeneration, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13024-022-00523-1
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- Article
Targeting aggregated tau turnover as a therapeutic strategy.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056366
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- Article
Conserved architecture of brain transcriptome changes between Alzheimer's disease and progressive supranuclear palsy in pathologically affected and unaffected regions.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054424
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- Article
Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo.
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- Life Science Alliance, 2021, v. 4, n. 7, p. 1, doi. 10.26508/lsa.202101108
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- Article
Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 6, p. 984, doi. 10.1002/alz.12254
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- Article
Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy.
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- Molecular Neurodegeneration, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13024-021-00453-4
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Precision therapeutic targets for COVID-19.
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- Virology Journal, 2021, v. 18, n. 1, p. 1, doi. 10.1186/s12985-021-01526-y
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- Article
Il-10 signaling reduces survival in mouse models of synucleinopathy.
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- NPJ Parkinson's Disease, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41531-021-00169-8
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- Article
Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions.
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- Acta Neuropathologica, 2021, v. 141, n. 3, p. 359, doi. 10.1007/s00401-021-02264-9
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- Article
Elucidating the relationship between TGF‐β signaling and Alzheimer's disease: Molecular and cell biology: Importance of Abeta/amyloid in brain changes.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043570
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Using seeding models to understand strain differences from Alzheimer's disease and pathological aging brains: Development of new models and analysis methods/seeding and spreading of proteinopathies.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043302
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- Article
Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila.
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- Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13195-020-00698-z
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- Article
Fyn depletion ameliorates tauP301L-induced neuropathology.
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- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00979-6
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Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 7, p. 1095, doi. 10.1002/alz.12059
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- Article
γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not.
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- Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13195-020-00622-5
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- Article
CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells.
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- Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.00735
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- Article
Diversity in Aβ deposit morphology and secondary proteome insolubility across models of Alzheimer-type amyloidosis.
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- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00911-y
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- Article
Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy.
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- Molecular Neurobiology, 2020, v. 57, n. 4, p. 1986, doi. 10.1007/s12035-019-01859-4
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- Article
Diffusion magnetic resonance imaging-derived free water detects neurodegenerative pattern induced by interferon-γ.
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- Brain Structure & Function, 2020, v. 225, n. 1, p. 427, doi. 10.1007/s00429-019-02017-1
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- Article
Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy.
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- Human Molecular Genetics, 2019, v. 28, n. 19, p. 3255, doi. 10.1093/hmg/ddz151
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- Article
P4‐613: SEMANTIC INTRUSION ERRORS DIFFERENTIATE AMYLOID POSITIVE AMNESTIC MILD COGNITIVE IMPAIRMENT FROM COGNITIVELY HEALTHY CONTROLS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1560, doi. 10.1016/j.jalz.2019.08.161
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P4‐614: PERCENTAGE OF INTRUSION ERRORS ON THE LASSI‐L COGNITIVE STRESS TEST DISCRIMINATES BETWEEN AMYLOID POSITIVE AND AMYLOID NEGATIVE INDIVIDUALS WITH AMNESTIC MILD COGNITIVE IMPAIRMENT AND EARLY DEMENTIA.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1560, doi. 10.1016/j.jalz.2019.08.162
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P4‐157: ROLE OF FYN IN A MOUSE MODEL OF TAU P301L TAUOPATHY.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1334, doi. 10.1016/j.jalz.2019.06.3819
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P4‐103: CELL‐TYPE SPECIFIC MECHANISTIC AND DIRECTIONAL TRANSCRIPTIONAL REGULATORY NETWORKS IN ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1314, doi. 10.1016/j.jalz.2019.06.3764
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- Article
P2‐427: THE RELATIONSHIP BETWEEN HISPANIC ETHNICITY, AMYLOID LOAD AND APOE4 CARRIER STATUS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P775, doi. 10.1016/j.jalz.2019.06.2834
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- Article