Works matching AU Goate, Alison M.

Results: 183

Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence.

Published in:

Bioinformatics, 2008, v. 24, n. 16, p. 1805, doi. 10.1093/bioinformatics/btn315

By:

Scott F. Saccone;
Nancy L. Saccone;
Gary E. Swan;
Pamela A. F. Madden;
Alison M. Goate;
John P. Rice;
Laura J. Bierut

Publication type:

Article

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.

Published in:

JAMA Neurology, 2021, v. 78, n. 1, p. 102, doi. 10.1001/jamaneurol.2020.3536

By:

Kunkle, Brian W.;
Schmidt, Michael;
Klein, Hans-Ulrich;
Naj, Adam C.;
Hamilton-Nelson, Kara L.;
Larson, Eric B.;
Evans, Denis A.;
De Jager, Phil L.;
Crane, Paul K.;
Buxbaum, Joe D.;
Ertekin-Taner, Nilufer;
Barnes, Lisa L.;
Fallin, M. Daniele;
Manly, Jennifer J.;
Go, Rodney C. P.;
Obisesan, Thomas O.;
Kamboh, M. Ilyas;
Bennett, David A.;
Hall, Kathleen S.;
Goate, Alison M.

Publication type:

Article

The Role of Cardiovascular Risk Factors and Stroke in Familial Alzheimer Disease.

Published in:

JAMA Neurology, 2016, v. 73, n. 10, p. 1231, doi. 10.1001/jamaneurol.2016.2539

By:

Tosto, Giuseppe;
Bird, Thomas D.;
Bennett, David A.;
Boeve, Bradley F.;
Brickman, Adam M.;
Cruchaga, Carlos;
Faber, Kelley;
Foroud, Tatiana M.;
Farlow, Martin;
Goate, Alison M.;
Graff-Radford, Neill R.;
Lantigua, Rafael;
Manly, Jennifer;
Ottman, Ruth;
Rosenberg, Roger;
Schaid, Daniel J.;
Schupf, Nicole;
Stern, Yaakov;
Sweet, Robert A.;
Mayeux, Richard

Publication type:

Article

Phenotypic Similarities Between Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease.

Published in:

JAMA Neurology, 2016, v. 73, n. 9, p. 1125, doi. 10.1001/jamaneurol.2016.1236

By:

Day, Gregory S.;
Musiek, Erik S.;
Roe, Catherine M.;
Norton, Joanne;
Goate, Alison M.;
Cruchaga, Carlos;
Cairns, Nigel J.;
Morris, John C.

Publication type:

Article

TREM2 Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis.

Published in:

JAMA Neurology, 2014, v. 71, n. 4, p. 449, doi. 10.1001/jamaneurol.2013.6237

By:

Cady, Janet;
Koval, Erica D.;
Benitez, Bruno A.;
Zaidman, Craig;
Jockel-Balsarotti, Jennifer;
Allred, Peggy;
Baloh, Robert H.;
Ravits, John;
Simpson, Ericka;
Appel, Stanley H.;
Pestronk, Alan;
Goate, Alison M.;
Miller, Timothy M.;
Cruchaga, Carlos;
Harms, Matthew B.

Publication type:

Article

Age-Specific Incidence Rates for Dementia and Alzheimer Disease in NIA-LOAD/NCRAD and EFIGA Families.

Published in:

JAMA Neurology, 2014, v. 71, n. 3, p. 315, doi. 10.1001/jamaneurol.2013.5570

By:

Vardarajan, Badri N.;
Faber, Kelley M.;
Bird, Thomas D.;
Bennett, David A.;
Rosenberg, Roger;
Boeve, Bradley F.;
Graff-Radford, Neill R.;
Goate, Alison M.;
Farlow, Martin;
Sweet, Robert A.;
Lantigua, Rafael;
Medrano, Martin Z.;
Ottman, Ruth;
Schaid, Daniel J.;
Foroud, Tatiana M.;
Mayeux, Richard

Publication type:

Article

C9orf72 Hexanucleotide Repeat Expansions in Clinical Alzheimer Disease.

Published in:

JAMA Neurology, 2013, v. 70, n. 6, p. 736, doi. 10.1001/2013.jamaneurol.537

By:

Harms, Matthew;
Benitez, Bruno A.;
Cairns, Nigel;
Cooper, Breanna;
Cooper, Paul;
Mayo, Kevin;
Carrell, David;
Faber, Kelley;
Williamson, Jennifer;
Bird, Tom;
Diaz-Arrastia, Ramon;
Foroud, Tatiana M.;
Boeve, Bradley F.;
Graff-Radford, Neill R.;
Mayeux, Richard;
Chakraverty, Sumitra;
Goate, Alison M.;
Cruchaga, Carlos

Publication type:

Article

Reduced variability of neural progenitor cells and improved purity of neuronal cultures using magnetic activated cell sorting.

Published in:

PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0213374

By:

Bowles, Kathryn R.;
T. C. W., Julia;
Qian, Lu;
Jadow, Benjamin M.;
Goate, Alison M.

Publication type:

Article

TARDBP 3′-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy.

Published in:

Acta Neuropathologica, 2009, v. 118, n. 5, p. 633, doi. 10.1007/s00401-009-0571-7

By:

Gitcho, Michael A.;
Bigio, Eileen H.;
Mishra, Manjari;
Johnson, Nancy;
Weintraub, Sandra;
Mesulam, Marsel;
Rademakers, Rosa;
Chakraverty, Sumi;
Cruchaga, Carlos;
Morris, John C.;
Goate, Alison M.;
Cairns, Nigel J.

Publication type:

Article

Heterogeneous effects of genetic risk for Alzheimer's disease on the phenome.

Published in:

Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01518-0

By:

Wu, Hei Man;
Goate, Alison M.;
O'Reilly, Paul F.

Publication type:

Article

Functional Characterization Improves Associations between Rare Non-Synonymous Variants in CHRNB4 and Smoking Behavior.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096753

By:

Haller, Gabe;
Li, Ping;
Esch, Caroline;
Hsu, Simon;
Goate, Alison M.;
Steinbach, Joe Henry

Publication type:

Article

Cis-Regulatory Variants Affect CHRNA5 mRNA Expression in Populations of African and European Ancestry.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080204

By:

Wang, Jen-Chyong;
Spiegel, Noah;
Bertelsen, Sarah;
Le, Nhung;
McKenna, Nicholas;
Budde, John P.;
Harari, Oscar;
Kapoor, Manav;
Brooks, Andrew;
Hancock, Dana;
Tischfield, Jay;
Foroud, Tatiana;
Bierut, Laura J.;
Steinbach, Joe Henry;
Edenberg, Howard J.;
Traynor, Bryan J.;
Goate, Alison M.

Publication type:

Article

Characterizing the Role of Brain Derived Neurotrophic Factor Genetic Variation in Alzheimer’s Disease Neurodegeneration.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0076001

By:

Honea, Robyn A.;
Cruchaga, Carlos;
Perea, Rodrigo D.;
Saykin, Andrew J.;
Burns, Jeffrey M.;
Weinberger, Daniel R.;
Goate, Alison M.

Publication type:

Article

Pathway Analysis of Smoking Quantity in Multiple GWAS Identifies Cholinergic and Sensory Pathways.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0050913

By:

Harari, Oscar;
Jen-Chyong Wang;
Bucholz, Kathleen;
Edenberg, Howard J.;
Heath, Andrew;
Martin, Nicholas G.;
Pergadia, Michele L.;
Montgomery, Grant;
Schrage, Andrew;
Bierut, Laura J.;
Madden, Pamela F.;
Goate, Alison M.

Publication type:

Article

Expression of Novel Alzheimer's Disease Risk Genes in Control and Alzheimer's Disease Brains.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0050976

By:

Karch, Celeste M.;
Jeng, Amanda T.;
Nowotny, Petra;
Cady, Janet;
Cruchaga, Carlos;
Goate, Alison M.

Publication type:

Article

Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031039

By:

Cruchaga, Carlos;
Chakraverty, Sumitra;
Mayo, Kevin;
Vallania, Francesco L. M.;
Mitra, Robi D.;
Faber, Kelley;
Williamson, Jennifer;
Bird, Tom;
Diaz-Arrastia, Ramon;
Foroud, Tatiana M.;
Boeve, Bradley F.;
Graff-Radford, Neill R.;
Jean, Pamela St.;
Lawson, Michael;
Ehm, Margaret G.;
Mayeux, Richard;
Goate, Alison M.

Publication type:

Article

Fine Mapping of Genetic Variants in BIN1, CLU, CR1 and PICALM for Association with Cerebrospinal Fluid Biomarkers for Alzheimer's Disease.

Published in:

PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0015918

By:

Kauwe, John S. K.;
Cruchaga, Carlos;
Karch, Celeste M.;
Sadler, Brooke;
Mo Lee;
Mayo, Kevin;
Latu, Wayne;
S ú a, Manti;
Fagan, Anne M.;
Holtzman, David M.;
Morris, John C.;
Goate, Alison M.

Publication type:

Article

Dissection of the Phenotypic and Genotypic Associations With Nicotinic Dependence.

Published in:

Nicotine & Tobacco Research, 2012, v. 14, n. 4, p. 425

By:

Chen, Li-Shiun;
Baker, Timothy B.;
Grucza, Richard;
Wang, Jen C.;
Johnson, Eric O.;
Breslau, Naomi;
Hatsukami, Dorothy;
Smith, Stevens S.;
Saccone, Nancy;
Saccone, Scott;
Rice, John P.;
Goate, Alison M.;
Bierut, Laura J.

Publication type:

Article

The collaborative study on the genetics of alcoholism: Genetics.

Published in:

Genes, Brain & Behavior, 2023, v. 22, n. 5, p. 1, doi. 10.1111/gbb.12856

By:

Johnson, Emma C.;
Salvatore, Jessica E.;
Lai, Dongbing;
Merikangas, Alison K.;
Nurnberger, John I.;
Tischfield, Jay A.;
Xuei, Xiaoling;
Kamarajan, Chella;
Wetherill, Leah;
Rice, John P.;
Kramer, John R.;
Kuperman, Samuel;
Foroud, Tatiana;
Slesinger, Paul A.;
Goate, Alison M.;
Porjesz, Bernice;
Dick, Danielle M.;
Edenberg, Howard J.;
Agrawal, Arpana

Publication type:

Article

5. Collaborative Study on the Genetics of Alcoholism: Functional genomics.

Published in:

Genes, Brain & Behavior, 2023, v. 22, n. 5, p. 1, doi. 10.1111/gbb.12855

By:

Gameiro‐Ros, Isabel;
Popova, Dina;
Prytkova, Iya;
Pang, Zhiping P.;
Liu, Yunlong;
Dick, Danielle;
Bucholz, Kathleen K.;
Agrawal, Arpana;
Porjesz, Bernice;
Goate, Alison M.;
Xuei, Xiaoling;
Kamarajan, Chella;
Tischfield, Jay A.;
Edenberg, Howard J.;
Slesinger, Paul A.;
Hart, Ronald P.

Publication type:

Article

ERRATUM: Genome‐wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward‐related ventral striatum activity in African‐ and European‐Americans.

Published in:

2019

By:

Wetherill, Leah;
Lai, Dongbing;
Johnson, Emma C.;
Anokhin, Andrey;
Bauer, Lance;
Bucholz, Kathleen K.;
Dick, Danielle M.;
Hariri, Ahmad R.;
Hesselbrock, Victor;
Kamarajan, Chella;
Kramer, John;
Kuperman, Samuel;
Meyers, Jacquelyn L.;
Nurnberger, John I.;
Schuckit, Marc;
Scott, Denise M.;
Taylor, Robert E.;
Tischfield, Jay;
Porjesz, Bernice;
Goate, Alison M.

Publication type:

Correction Notice

Genome‐wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward‐related ventral striatum activity in African‐ and European‐Americans.

Published in:

Genes, Brain & Behavior, 2019, v. 18, n. 6, p. N.PAG, doi. 10.1111/gbb.12580

By:

Wetherill, Leah;
Lai, Dongbing;
Johnson, Emma C.;
Anokhin, Andrey;
Bauer, Lance;
Bucholz, Kathleen K.;
Dick, Danielle M.;
Hariri, Ahmad R.;
Hesselbrock, Victor;
Kamarajan, Chella;
Kramer, John;
Kuperman, Samuel;
Meyers, Jacquelyn L.;
Nurnberger, John I.;
Schuckit, Marc;
Scott, Denise M.;
Taylor, Robert E.;
Tischfield, Jay;
Porjesz, Bernice;
Goate, Alison M.

Publication type:

Article

Coding variants in TREM2 increase risk for Alzheimer's disease.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 21, p. 5838, doi. 10.1093/hmg/ddu277

By:

Jin, Sheng Chih;
Benitez, Bruno A.;
Karch, Celeste M.;
Cooper, Breanna;
Skorupa, Tara;
Carrell, David;
Norton, Joanne B.;
Hsu, Simon;
Harari, Oscar;
Cai, Yefei;
Bertelsen, Sarah;
Goate, Alison M.;
Cruchaga, Carlos

Publication type:

Article

Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37437-5

By:

Brase, Logan;
You, Shih-Feng;
D'Oliveira Albanus, Ricardo;
Del-Aguila, Jorge L.;
Dai, Yaoyi;
Novotny, Brenna C.;
Soriano-Tarraga, Carolina;
Dykstra, Taitea;
Fernandez, Maria Victoria;
Budde, John P.;
Bergmann, Kristy;
Morris, John C.;
Bateman, Randall J.;
Perrin, Richard J.;
McDade, Eric;
Xiong, Chengjie;
Goate, Alison M.;
Farlow, Martin;
Sutherland, Greg T.;
Kipnis, Jonathan

Publication type:

Article

Multiple distinct CHRNB3- CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans.

Published in:

Addiction, 2014, v. 109, n. 5, p. 814, doi. 10.1111/add.12478

By:

Culverhouse, Robert C.;
Johnson, Eric O.;
Breslau, Naomi;
Hatsukami, Dorothy K.;
Sadler, Brooke;
Brooks, Andrew I.;
Hesselbrock, Victor M.;
Schuckit, Marc A.;
Tischfield, Jay A.;
Goate, Alison M.;
Saccone, Nancy L.;
Bierut, Laura J.

Publication type:

Article

CHRNB3 is more strongly associated with Fagerström Test for Cigarette Dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results.

Published in:

2012

By:

Rice, John P.;
Hartz, Sarah M.;
Agrawal, Arpana;
Almasy, Laura;
Bennett, Siiri;
Breslau, Naomi;
Bucholz, Kathleen K.;
Doheny, Kimberly F.;
Edenberg, Howard J.;
Goate, Alison M.;
Hesselbrock, Victor;
Howells, William B.;
Johnson, Eric O.;
Kramer, John;
Krueger, Robert F.;
Kuperman, Samuel;
Laurie, Cathy;
Manolio, Teri A.;
Neuman, Rosalind J.;
Nurnberger, John I.

Publication type:

Journal Article

Interplay of genetic risk factors and parent monitoring in risk for nicotine dependence.

Published in:

Addiction, 2009, v. 104, n. 10, p. 1731, doi. 10.1111/j.1360-0443.2009.02697.x

By:

Chen, Li‐Shiun;
Johnson, Eric O.;
Breslau, Naomi;
Hatsukami, Dorothy;
Saccone, Nancy L.;
Grucza, Richard A.;
Wang, Jen C.;
Hinrichs, Anthony L.;
Fox, Louis;
Goate, Alison M.;
Rice, John P.;
Bierut, Laura J.

Publication type:

Article

Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerström Test for Nicotine Dependence.

Published in:

Addiction, 2009, v. 104, n. 3, p. 471, doi. 10.1111/j.1360-0443.2008.02445.x

By:

Agrawal, Arpana;
Pergadia, Michele L.;
Balasubramanian, Sumitra;
Saccone, Scott F.;
Hinrichs, Anthony L.;
Saccone, Nancy L.;
Breslau, Naomi;
Johnson, Eric O.;
Hatsukami, Dorothy;
Martin, Nicholas G.;
Montgomery, Grant W.;
Goate, Alison M.;
Rice, John P.;
Bierut, Laura J.;
Madden, Pamela A.F.

Publication type:

Article

Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case–control study.

Published in:

Addiction, 2008, v. 103, n. 6, p. 1027, doi. 10.1111/j.1360-0443.2008.02236.x

By:

Agrawal, Arpana;
Pergadia, Michele L.;
Saccone, Scott F.;
Hinrichs, Anthony L.;
Lessov‐Schlaggar, Christina N.;
Saccone, Nancy L.;
Neuman, Rosalind J.;
Breslau, Naomi;
Johnson, Eric;
Hatsukami, Dorothy;
Montgomery, Grant W.;
Heath, Andrew C.;
Martin, Nicholas G.;
Goate, Alison M.;
Rice, John P.;
Bierut, Laura J.;
Madden, Pamela A. F.

Publication type:

Article

Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology.

Published in:

2022

By:

Morris, John C;
Weiner, Michael;
Xiong, Chengjie;
Beckett, Laurel;
Coble, Dean;
Saito, Naomi;
Aisen, Paul S;
Allegri, Ricardo;
Benzinger, Tammie L S;
Berman, Sarah B;
Cairns, Nigel J;
Carrillo, Maria C;
Chui, Helena C;
Chhatwal, Jasmeer P;
Cruchaga, Carlos;
Fagan, Anne M;
Farlow, Martin;
Fox, Nick C;
Ghetti, Bernardino;
Goate, Alison M

Publication type:

journal article

Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's Disease.

Published in:

Annals of Neurology, 2024, v. 95, n. 4, p. 625, doi. 10.1002/ana.26864

By:

Vance, Jeffery M.;
Farrer, Lindsay A.;
Huang, Yadong;
Cruchaga, Carlos;
Hyman, Bradley T.;
Pericak‐Vance, Margaret A.;
Goate, Alison M.;
Greicius, Michael D.;
Griswold, Anthony J.;
Haines, Jonathan L.;
TCW, Julia;
Schellenberg, Gerard D.;
Tsai, Li‐Huei;
Herz, Joachim;
Holtzman, David M.

Publication type:

Article

Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome.

Published in:

Annals of Neurology, 2021, v. 89, n. 1, p. 54, doi. 10.1002/ana.25918

By:

Andrews, Shea J.;
Fulton‐Howard, Brian;
O'Reilly, Paul;
Marcora, Edoardo;
Goate, Alison M.;
Farrer, Lindsay A.;
Haines, Jonathan L.;
Mayeux, Richard;
Naj, Adam C.;
Pericak‐Vance, Margaret A.;
Schellenberg, Gerard D.;
Wang, Li‐San

Publication type:

Article

Evaluating brain age using functional connectivity in autosomal dominant Alzheimer disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S9, p. 1, doi. 10.1002/alz.093634

By:

Macharia, Kiana Angela;
Gordon, Brian A.;
Wisch, Julie K.;
Metcalf, Nicholas V;
Roman, June;
Benzinger, Tammie L.S.;
Cruchaga, Carlos;
Goate, Alison M.;
Hassenstab, Jason J.;
Ibanez, Laura;
Karch, Celeste M.;
Llibre‐Guerra, Jorge J.;
Morris, John C.;
Perrin, Richard J.;
Renton, Alan E.;
Supnet, Charlene B;
Xiong, Chengjie;
Bateman, Randall J.;
McDade, Eric;
Ances, Beau

Publication type:

Article

Modeling the influence of presenilin‐1 mutation position on primary outcomes of a gantenerumab trial: findings from the DIAN‐TU‐001 study.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S8, p. 1, doi. 10.1002/alz.095570

By:

McCullough, Austin A.;
Cao, Yuchen;
Chen, Charles D.;
Gordon, Brian A.;
Cruchaga, Carlos;
Goate, Alison M.;
Hassenstab, Jason J.;
Ibanez, Laura;
Li, Yan;
Perrin, Richard J.;
Renton, Alan E.;
Xiong, Chengjie;
Salloway, Stephen;
Llibre‐Guerra, Jorge J.;
Clifford, David B.;
McDade, Eric;
Bateman, Randall J.;
Benzinger, Tammie L.S.;
Wang, Guoqiao;
Joseph‐Mathurin, Nelly

Publication type:

Article

Use of human iPSC lines to model Alzheimer's genetic risk and understand disease mechanism.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S6, p. 1, doi. 10.1002/alz.087340

By:

Goate, Alison M.;
Münch, Alexandra;
Molina, Carmen Romero;
Podlesny‐Drabiniok, Anna;
Peppler, Grace;
Garretti, Francesca;
Patel, Tulsi;
Lee, Hyo;
Marcora, Edoardo

Publication type:

Article

Beyond GWAS: Investigating Structural Variants and Their Segregation in Familial Alzheimer's Disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S2, p. 1, doi. 10.1002/alz.092677

By:

Gunasekaran, Tamil Iniyan;
Reyes‐Dumeyer, Dolly;
Corvelo, André;
Clarke, Wayne E.;
Evani, Uday S.;
Byrska‐Bishop, Marta S.;
Basile, Anna O.;
Runnels, Alexi;
Musunuri, Rajeeva O.;
Narzisi, Giuseppe;
Faber, Kelley M.;
Goate, Alison M.;
Boeve, Brad F.;
Cruchaga, Carlos;
Pericak‐Vance, Margaret A.;
Haines, Jonathan L.;
Rosenberg, Roger N;
Tsuang, Debby W;
Mejia, Diones Rivera;
Medrano, Martin

Publication type:

Article

Identification of genetically driven Therapeutic Targets for Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.093138

By:

Goate, Alison M.;
Marcora, Edoardo;
Cruchaga, Carlos

Publication type:

Article

Systematic dissection of the genomic mechanisms underlying differential tauopathy risks associated with the human 17q21.31 locus.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.089768

By:

Qi, Le;
Pedicone, Chiara;
Bowles, Kathryn;
Yin, Jiani;
Goate, Alison M.;
Geschwind, Daniel H.

Publication type:

Article

Mitochondrial DNA depletion induces AD like phenotypes in neuronal and glial cells.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.089073

By:

Molina, Carmen Romero;
Lysaker, Colton R;
Roberts, Anysja;
Gilmore, Caleb;
See, Wen Yi;
Liu, Yiyuan;
Pa, Judy;
Swerdlow, Russell H;
Goate, Alison M.;
Andrews, Shea J;
Wilkins, Heather M

Publication type:

Article

Elucidating the role of mitochondrial Alzheimer's Disease risk gene LACTB in myeloid cells.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.086622

By:

Molina, Carmen Romero;
See, Wen Yi;
Patel, Tulsi;
Liu, Yiyuan;
Marcora, Edoardo;
Goate, Alison M.

Publication type:

Article

Cognitive reserve influences symptom onset and longitudinal decline in Dominantly Inherited Alzheimer's Disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.086295

By:

Llibre‐Guerra, Jorge J.;
Lu, Ruijin;
Renton, Alan E.;
Gordon, Brian A.;
Benzinger, Tammie L.S.;
Aschenbrenner, Andrew J.;
Hassenstab, Jason J.;
Xiong, Chengjie;
Perrin, Richard J.;
Ibanez, Laura;
Goate, Alison M.;
Cruchaga, Carlos;
Morris, John C.;
Daniels, Alisha;
McDade, Eric;
Bateman, Randall J.

Publication type:

Article

Novel avenues of tau research.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 2240, doi. 10.1002/alz.13533

By:

Sexton, Claire E.;
Bitan, Gal;
Bowles, Kathryn R.;
Brys, Miroslaw;
Buée, Luc;
Maina, Mahmoud Bukar;
Clelland, Claire D.;
Cohen, Ann D.;
Crary, John F.;
Dage, Jeffrey L.;
Diaz, Kristophe;
Frost, Bess;
Gan, Li;
Goate, Alison M;
Golbe, Lawrence I.;
Hansson, Oskar;
Karch, Celeste M.;
Kolb, Hartmuth C.;
La Joie, Renaud;
Lee, Suzee E.

Publication type:

Article

Validation of newly derived polygenic risk scores for dementia in a prospective study of older individuals.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 12, p. 5333, doi. 10.1002/alz.13113

By:

Yu, Chenglong;
Ryan, Joanne;
Orchard, Suzanne G.;
Robb, Catherine;
Woods, Robyn L.;
Wolfe, Rory;
Renton, Alan E.;
Goate, Alison M.;
Brodtmann, Amy;
Shah, Raj C.;
Chong, Trevor T.‐J.;
Sheets, Kerry;
Kyndt, Christopher;
Sood, Ajay;
Storey, Elsdon;
Murray, Anne M.;
McNeil, John J.;
Lacaze, Paul

Publication type:

Article

APOE and immunity: Research highlights.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 6, p. 2677, doi. 10.1002/alz.13020

By:

Kloske, Courtney M.;
Barnum, Christopher J.;
Batista, Andre F.;
Bradshaw, Elizabeth M.;
Brickman, Adam M.;
Bu, Guojun;
Dennison, Jessica;
Gearon, Mary D.;
Goate, Alison M.;
Haass, Christian;
Heneka, Michael T.;
Hu, William T.;
Huggins, Lenique K. L.;
Jones, Nahdia S.;
Koldamova, Radosveta;
Lemere, Cynthia A.;
Liddelow, Shane A.;
Marcora, Edoardo;
Marsh, Samuel E.;
Nielsen, Henrietta M.

Publication type:

Article

Discovery and validation of dominantly Inherited Alzheimer's Disease mutations in populations from Latin America.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.060433

By:

Llibre‐Guerra, Jorge J;
Takada, Leonel Tadao;
Verson, Carmen Alaez;
Burgute, Bhagyashri;
Nitrini, Ricardo;
Sosa‐Ortiz, Ana Luisa;
Castilhos, Raphael Machado;
Chaves, Marcia L Fagundes;
Ibarrola, Mariana Longoria;
Carrillo‐Sanchez, Karol;
Brucki, Sonia Maria Dozzi;
Flores‐Lagunes, Luis Leonardo;
Molina, Carolina;
Olivares, Marcos Jimenez;
Ziegemeier, Ellen;
Goate, Alison M.;
Cruchaga, Carlos;
Renton, Alan E.;
Fernandez, Maria Victoria;
Day, Gregory S

Publication type:

Article

Current directions in tau research: Highlights from Tau 2020.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 988, doi. 10.1002/alz.12452

By:

Sexton, Claire;
Snyder, Heather;
Beher, Dirk;
Boxer, Adam L.;
Brannelly, Pat;
Brion, Jean‐Pierre;
Buée, Luc;
Cacace, Angela M.;
Chételat, Gaël;
Citron, Martin;
DeVos, Sarah L.;
Diaz, Kristophe;
Feldman, Howard H.;
Frost, Bess;
Goate, Alison M.;
Gold, Michael;
Hyman, Bradley;
Johnson, Keith;
Karch, Celeste M.;
Kerwin, Diana R.

Publication type:

Article

The location of PSEN1 pathogenic variants in transmembrane vs. cytoplasmic domains may alter neurodegenerative and cognitive trajectories: Findings from the DIAN study.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.050864

By:

Schultz, Stephanie A.;
Schultz, Aaron P.;
Joseph‐Mathurin, Nelly;
McDade, Eric;
Klunk, William E.;
Fox, Nick C.;
Levin, Johannes;
Hassenstab, Jason;
Goate, Alison M.;
Hanseeuw, Bernard J;
Lee, Jae‐Hong;
Fitzpatrick, Colleen D.;
Jucker, Mathias;
Allegri, Ricardo Francisco;
Benzinger, Tammie L.S.;
Berman, Sarah;
Chui, Helena C.;
Cruchaga, Carlos;
Fagan, Anne M.;
Gordon, Brian A.

Publication type:

Article

Systematic validation of variants of unknown significance in PSEN1.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.058686

By:

Burgute, Bhagyashri;
Renton, Alan E.;
Ziegemeier, Ellen;
Cruchaga, Carlos;
Goate, Alison M.;
McDade, Eric;
Llibre‐Guerra, Jorge J;
Karch, Celeste M.

Publication type:

Article

An enrichment of rare variants and the lysosomal pathways are important contributors to early onset Alzheimer disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055341

By:

Fernandez, Victoria;
Pottier, Cyril P;
Budde, John P.;
Wang, Fengxian;
Norton, Joanne;
Gentsch, Jen;
Morris, John C.;
Goate, Alison M.;
Beecham, Gary W.;
Reitz, Christiane;
Ertekin‐Taner, Nilufer;
Dickson, Dennis W;
Graff‐Radford, Neill R.;
Boeve, Bradley F.;
Petersen, Ronald C.;
Kauwe, John;
Holstege, Henne;
Hulsman, Marc;
Bellenguez, Céline;
Lambert, Jean‐Charles

Publication type:

Article

Defining the role of PLD3 in Alzheimer disease pathology.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054611

By:

Rosene, Matthew J;
Hsu, Simon;
Martinez, Rita;
Norton, Joanne;
Yan, Ping;
Cirrito, John R;
Lee, Jin‐Moo;
Cuervo, Ana Maria;
Goate, Alison M.;
Cruchaga, Carlos;
Karch, Celeste M.

Publication type:

Article